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Start Over Topic enzyme activation Topic hydroxylation Publication Type Academic Journals

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1. Deazaflavins as mediators in light-driven cytochrome P450 catalyzed hydroxylationsElectronic supplementary information (ESI) available: Experimental details and additional control experiments. See DOI: 10.1039/b913863c.

Author

Felipe E. ZillyThese authors contributed equally to this paper., Andreas Taglieber, Frank Schulz, Frank Hollmann, and Manfred T. Reetz

Subjects
*FLAVINS, *CYTOCHROME P-450, *ADENINE nucleotides, *HYDROXYLATION, *ENZYME activation
Abstract

A light-driven deazaflavin-dependent direct enzyme regeneration system has been developed for a P450-BM3 catalyzed CH-activating hydroxylation, thereby avoiding the need for the expensive NADPH cofactor. [ABSTRACT FROM AUTHOR]

Published
2009
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