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1. From plant to drug: ionic liquids for the reactive dissolution of biomassElectronic supplementary information (ESI) available: Calibration curves, copies of chromatograms and spectra of pure and crude active components 2–4. See DOI: 10.1039/c1gc15058hThis paper was published as part of the themed issue of contributions from the Green Solvents – Alternative Fluids in Science and Application conference held in Berchtesgaden, October 2010.

Author

Ressmann, Anna K., Gaertner, Peter, and Bica, Katharina

Subjects
*IONIC liquids, *SOLUTION (Chemistry), *INTERMEDIATES (Chemistry), *ORGANIC synthesis, *ANTIVIRAL agents, *ILLICIUM verum, *BIOMASS
Abstract

We present an ionic liquid (IL) strategy for the reactive dissolution of star anise seeds using different Brønsted-acidic ionic liquids as the solvent and reaction media towards the isolation of important pharmaceutical intermediates; this procedure provides a single-step, higher yielding and environmentally benign strategy towards the synthesis of the anti-influenza drug Tamiflu™. [ABSTRACT FROM AUTHOR]

Published
2011
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