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In order to improve the image quality of a coded-aperture-based gamma-ray imaging apparatus, a method for removing Compton scattered and other multipixel events is presented that removes inaccurate position estimations from the data stream. In coded-aperture gamma-ray imaging detectors, scattering events that are shared between different partitions in the active medium can result in the inaccurate determination of the initial gamma-ray interaction position, the result of which is distortion in the angular reconstruction mapping. For coded-aperture system in which the rapid localization and identification of the emitting source is important, the distortion due to scattered radiation can increase the integration time of the system. We show, in both software and hardware implementations using a cerium-doped gadolinium aluminum gallium garnet pixelated scintillator array, that filtering the data to remove multipixel events can improve the image quality despite the efficiency loss associated with not utilizing all of the interactions within the detector. [ABSTRACT FROM AUTHOR]

Y2SiO5: Ce (YSO) scintillation with characteristics of high light yield, fast decay time, and high Compton scattering fraction shows good application potential for Compton imaging. In this article, we propose a 3-D scintillator detector, which is segmented by the YSO monolithic rods and pixelated by subsurface laser engraving (SSLE) in the depth direction. Two arrays of silicon photomultipliers are optically coupled to the YSO array at each end, in which the pixels are designed for a one-to-one match. By identifying the location number of array pixels and measuring the depth of interaction (DOI) of pixelated scintillator rods, the interaction coordinates of gamma photon can be obtained accurately. After energy-consistent calibration, the energy resolutions of the pixels in the 3-D detector were evaluated. The imaging test results indicate that the detector has the capability to locate a 0.1-μSv/h 137-Cs gamma-ray source within 90 s in 4π field of view (FOV). The efficiency of the imaging events is 2.2%. By using the maximum-likelihood expectation–maximization (MLEM) algorithm with ten iterations, the full width at half maximum (FWHM) of the reconstructed hotspot decreases to less than 9.0°. This configuration mainly simplifies the calculation of interaction coordinates compared to the center of the gravity method. Moreover, the higher segment precision for DOI estimation is realized due to the SSLE technique. The 3-D scintillator detector achieves 4π Compton imaging with high detection efficiency and high localization accuracy. [ABSTRACT FROM AUTHOR]

Image-reconstruction with Compton-scattered photons is a nonlinear problem, because it involves both the linear process of scattering and the exponential pre- and post-scatter attenuation. For thin and light objects and with high-energy photons, the exponential terms can be ignored, rendering the problem linear. We show that when attenuation is significant, linearity can also be accomplished by considering scattering as a scaling factor and with subsequent logarithmic transformation, the image-reconstruction problem is converted into a transmission-like problem along the travel lines of incident and scattered radiation. It is shown that this formulation produces images qualitatively reflecting object features in a manner similar to that of backprojection in conventional computed tomography. This is done without the need for calibration or scaling of measurements. The theoretical aspects of the introduced mathematical formulation are developed for idealized pencil-beams, adapted approximately to fan-beam configurations, and applied to imaging with laboratory-acquired measurements. The introduced transmission-like formulation and calibration-free aspects should promote wider use of scatter imaging. [ABSTRACT FROM AUTHOR]

To improve the quantitative accuracy of linear attenuation coefficients measured by computed tomography (CT), we used a single scatter model to estimate the Compton scatter distribution and then a polychromatic image reconstruction algorithm, namely the iterative maximum-likelihood polychromatic algorithm for CT (IMPACT), was implemented to include scatter correction (SC). To perform the IMPACT, the X-ray spectra of a tube were estimated via an expectation-maximization (EM) algorithm with SC. To test the accuracy of the estimated spectra, the projection images of cubic phantoms containing different depths of polymethylmethacrylate (PMMA) were acquired. The percentage of root mean square errors (%RMSE) of the measured transmission data and calculated transmission values were used to evaluate the accuracy of the estimated spectra. In addition, a hydroxylapatite (HA) phantom was used to study streak artifacts and evaluate the accuracy of the linear attenuation coefficients estimated using the IMPACT with SC. The %RMSE of the EM-with-SC estimated spectra were all lower than 1% and were also smaller than that without SC. The error in the quantification of the HA linear attenuation was only about 3% after SC. Our results showed that the quantitative accuracy of the linear attenuation coefficients measured with a cone beam CT was improved when the IMPACT with SC was used. [ABSTRACT FROM AUTHOR]

The Rotating Scatter Mask (RSM) system is an inexpensive retrofit that provides imaging capabilities to scintillating detectors. Unlike traditional collimator systems that primarily absorb photons in order to form an image, this system primarily scatters the photons. Over a single rotation, there is a unique, smooth response curve for each defined source position. Testing was conducted using MCNPX simulations. Image reconstruction was performed using a chi-squared reconstruction technique. A simulated 100 uCi, Cs-137 source at 10 meters was detected after a single, 50-second rotation when a uniform terrestrial background was present. A Cs-137 extended source was also tested. The RSM field-of-view is 360 degrees azimuthally as well as 54 degrees above and 54 degrees below the horizontal plane. Since the RSM is built from polyethylene, the overall cost and weight of the system is low. The system was designed to search for lost or stolen radioactive material, also known as the orphan source problem. [ABSTRACT FROM PUBLISHER]

The requirement to scope and analyze hidden parts of the human body and the limitations of current imaging technologies is motivating the development of novel approaches. In clinical PET/CT systems, the attenuation and activity maps of the studied body region are recovered from measurements. However, the modeling of Compton scattering enables to obtain the attenuation map through the electron density directly from transmission data, thus obviating the need of a CT scan. In this context, a bimodality imaging approach (gamma-ray transmission/emission imaging) using scattered radiation referred to as Compton scattering tomography (CST) is presented. This concept is modeled by two generalized Radon transforms and proposes to reconstruct the electron density, the attenuation map, and the activity concentration of the studied body region. Simulation results demonstrate the feasibility and viability of this novel imaging concept. The present approach could be an interesting alternative to current tomographic imaging techniques. [ABSTRACT FROM PUBLISHER]

Imaging processes built on the Compton scattering effect are currently under intense investigation. However, despite many innovative contributions, this topic still pose a formidable mathematical and technical challenge. In this work, we argue that, in the framework of single-photon emission imaging, collecting Compton scattered radiation from an emitting object, allows to image the radiotracer distribution in vivo. Data is acquired by a stationary collimated gamma camera under the form of compounded conical projections of the activity density function. Mathematically, the image formation process is described by the so-called Compounded Conical Radon Transform (CCRT) and three-dimensional object reconstruction is based on an inversion formula of the CCRT. We perform numerical simulations to show the feasibility of this new imaging modality, which offers the remarkable advantage of operating in stationary mode without the need of bulky and cumbersome spatial rotational mechanism of conventional gamma cameras. This is highly attractive for applications in medical imaging, industrial non-destructive evaluation, nuclear waste storage surveillance and homeland security monitoring. Finally, to improve drastically the sensitivity, we introduce a new feature allowing to acquire data without mechanical collimation and support the findings with some preliminary simulation results. [ABSTRACT FROM AUTHOR]

Today we face serious threats from radiological dispersion devices, improvised nuclear devices, and unsecured nuclear materials. Detectors which are currently used to detect and characterize these radioactive materials (or the radioactive materials within larger assemblies) suffer from large background rates. In addition, these detectors have only minimal ability to localize the position of the source without the use of mechanical collimators - which reduce efficiency. Imaging detectors using the Compton scattering process have the potential to provide greatly improved sensitivity through their ability to reject off-source background by localizing the source. We are developing a prototype device using readily available detector systems to explore Compton imaging technology. Our aim is to build a proof-of-concept device to study the Compton technology and to benchmark simulation efforts that will guide development of larger, more efficient devices that would be needed for deployment in the field. Here we discuss the concept of our detector design and results from Monte Carlo simulations of our prototype detector. We present an extension of an imaging technique used for gamma-ray astronomy to near-field sources [ABSTRACT FROM PUBLISHER]

A 3-D X-ray imaging system that eliminates the rotation process associated with tomographic systems is introduced. The system relies on measuring the intensity of Compton scattered radiation in two directions mutually perpendicular to an incident beam that rectilinearly scans the object. These measurements, along with transmission measurements obtained from one-side exposure of the object are utilized to reconstruct 3-D images of three physical parameters: two attenuation coefficients corresponding to the incident and scattered energies, and the electron-density in each voxel. This part of the paper addresses the theoretical and physical aspects associated with the image reconstruction process, and presents examples of images reconstructed from experimental results. [ABSTRACT FROM AUTHOR]