17 results on '"Yang, Huiqiang"'
Search Results
2. Targeting TAM-secreted S100A9 effectively enhances the tumor-suppressive effect of metformin in treating lung adenocarcinoma
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Sui, Qihai, Hu, Zhengyang, Liang, Jiaqi, Lu, Tao, Bian, Yunyi, Jin, Xing, Li, Ming, Huang, Yiwei, Yang, Huiqiang, Wang, Qun, Lin, Zongwu, Chen, Zhencong, and Zhan, Cheng
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- 2024
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3. Efficient removal of aqueous organic pollutants by well-ordered layered manganese oxide nanocomposites: Impacts of interlayer spacing and nanoconfinement
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Wang, Zhiqiang, Shi, Yafang, Yang, Kangjie, Yang, Huiqiang, Zhao, Haoran, Xi, Mengning, Zhang, Chi, Zhu, Lingyan, and Jia, Hanzhong
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- 2023
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4. Construction and preliminary investigation of a novel dengue serotype 4 chimeric virus using Japanese encephalitis vaccine strain SA14-14-2 as the backbone
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Li, Zhushi, Yang, Huiqiang, Yang, Jian, Lin, Hua, Wang, Wei, Liu, Lina, Zhao, Yu, Liu, Li, Zeng, Xianwu, Yu, Yongxin, and Li, Yuhua
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- 2014
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5. Development of a molten salt thermal conductivity model and database for advanced energy systems.
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Yang, Huiqiang, Gallagher, Ryan, Chartrand, Patrice, and Gheribi, Aïmen E.
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THERMAL conductivity , *FUSED salts , *DATABASES , *HEAT storage , *THERMOPHYSICAL properties - Abstract
A theoretical model for predicting the temperature-dependent thermal conductivity of pure molten salts, both simple and complex, is presented. The model is based on kinetic theory and incorporates Einstein's concept of minimum thermal conductivity. The proposed formulation can consider the magnitude of thermal conductivity for separate salts, including complex and polymerizing salts. The model's thermal conductivity predictions were compared to reliable experimental data in the literature and a previously recommended thermal conductivity model using the Bland–Altman method. The comparison showed accurate thermal conductivity predictions relative to the reliable experimental data, with an average deviation of 10% or less. The model's predictions were also compared to the experimental data on an individual basis for halide, divalent halide, carbonate, nitrate, nitrite, sulfate, and hydroxide molten salts, demonstrating reliable predictions for the molten salts studied and improved accuracy over the previous model. Lastly, a database of simple and complex molten salts, with the necessary parameters for modeling their thermal conductivity, is recommended. • A database for the thermal conductivity of more than 60 molten salts is presented. • The model is developed based on the kinetic theory. • Few key thermophysical properties are required for the model parameterization. • The predictive capability of the model is found to be very good. • The model is valid from the melting temperature up to 75% of the boiling temperature. [ABSTRACT FROM AUTHOR]
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- 2023
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6. Energy efficient k-barrier coverage in limited mobile wireless sensor networks
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Ma, Huan, Li, Deying, Chen, Wenping, Zhu, Qinghua, and Yang, Huiqiang
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- 2012
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7. Fault-tolerant routing: [formula omitted]-inconnected many-to-one routing in wireless networks
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Li, Deying, Wang, Yuexuan, Zhu, Qinghua, and Yang, Huiqiang
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- 2011
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8. A novel flux mapping system for high-flux solar simulators based on the indirect method.
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Xiao, Jun, Yang, Huiqiang, Wei, Xiudong, and Li, Zengyao
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CARTOGRAPHY , *SOLAR radiation , *DETECTOR circuits , *ERROR analysis in mathematics , *OPTICAL beam induced current - Abstract
Highlights • A novel flux mapping system which featured two Lambertian targets was first introduced and developed. • The design principle and the hardware implementation were presented in detail. • The performance of a multi-lamps high-flux solar simulator was evaluated by the flux mapping system. • The repeatability precision and the relative error of the flux mapping system were tested and analyzed. Abstract It is an important and challenging work to measure the energy flux density distribution of the concentrated radiation during the concentrating solar power applications. In order to evaluate the performance of a multi-lamps high-flux solar simulator, a novel flux mapping system based on the indirect method has been developed. It features two Lambertian targets. One is a stationary water-cooled Lambertian target where there is a circular hole in the center used to install a flux sensor. The other is a movable Lambertian target used to cover the flux sensor when shooting the concentrated light beam image. This kind of design can obtain the gray value of flux sensor region directly and does not require the interpolation in the sensor-influencing area. The design theory and principle, the hardware implementation and the experimental validation of this flux mapping system have been presented in detail. The repeatability experiments and the error analyses showed that the total relative errors of this flux mapping system were ±8.1% with a repeatability of 1.1%, and ±8.5% with a repeatability of 2.7%, for evaluating the flux and the total radiant power, respectively. [ABSTRACT FROM AUTHOR]
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- 2019
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9. Japanese encephalitis virus/yellow fever virus chimera is safe and confers full protection against yellow fever virus in intracerebrally challenged mice.
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Yang, Huiqiang, Yang, Huan, Li, Zhushi, Liu, Lina, Wang, Wei, He, Ting, Fan, Fengming, Sun, Yan, Liu, Jie, Li, Yuhua, and Zeng, Xianwu
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JAPANESE B encephalitis , *VACCINE effectiveness , *MEDICATION safety , *PUBLIC health , *LABORATORY mice , *VACCINATION - Abstract
Yellow fever (YF) is an acute viral haemorrhagic disease caused by the yellow fever virus (YFV), which remains a potential threat to public health. The live-attenuated YF vaccine (17D strain) is a safe and highly effective measure against YF. However, increasing adverse events have been associated with YF vaccinations in recent years; thus, safer, alternative vaccines are needed. In this study, using the Japanese encephalitis live vaccine strain SA14-14–2 as a backbone, a novel chimeric virus was constructed by replacing the pre-membrane (prM) and envelope (E) genes with their YFV 17D counterparts.The chimeric virus exhibited a reduced growth rate and a much smaller plaque morphology than did either parental virus. Furthermore, the chimera was much less neurovirulent than was YF17D and protected mice that were challenged with a lethal dose of the YF virus. These results suggest that this chimera has potential as a novel attenuated YF vaccine. [ABSTRACT FROM AUTHOR]
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- 2018
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10. Trace determination of organophosphate esters in white wine, red wine, and beer samples using dispersive liquid-liquid microextraction combined with ultra-high-performance liquid chromatography–tandem mass spectrometry.
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Pang, Long, Yang, Huiqiang, Yang, Peijie, Zhang, Hongzhong, and Zhao, Jihong
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WINE analysis , *LIQUID-liquid extraction , *LIQUID chromatography-mass spectrometry , *ESTERS , *BEER analysis , *PHOSPHATES - Abstract
In this study, dispersive liquid-liquid microextraction coupled with ultra-high-performance liquid chromatography–tandem mass spectrometry was developed for the analysis of five representative organophosphate esters (OPEs) in wine samples. Under optimized conditions, the proposed method resulted in good linearity ( R 2 > 0.9933) over the range of 0.1–100 μg L −1 , with limits of detection (LODs, S/N = 3) and quantification (LOQs, S/N = 10) in the ranges of 0.48–18.8 ng L −1 and 1.58–62.5 ng L −1 , respectively. Inter- and intra-assay precisions of RSD% ranged from 3.21% to 6.13% and from 1.69% to 7.63%, respectively. The spiked recoveries of target OPEs from white wine, red wine, and beer samples were in the ranges of 80–122%, 76–120%, and 76–110%, respectively, at two different concentration levels. The total concentrations of five OPEs found in white wine, red wine, and beer samples were in the ranges of 0.29–0.85 μg L −1 , 1.00–3.05 μg L −1 , and 0.86–1.47 μg L −1 , respectively. [ABSTRACT FROM AUTHOR]
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- 2017
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11. Price and Quality Management with Strategic Consumers: Whether to Introduce a High or Low Product Variant.
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Ye, Taofeng and Yang, Huiqiang
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DIRECT costing , *COST structure , *CONSUMER behavior , *PRODUCT quality , *CONSUMERS - Abstract
• Markdown only is not optimal for firms in most cases. • Sometimes, the firm is best to simultaneous markup/markdown and upgrade. • Firm's strategies on price and quality are contingent on quality cost structure. We consider a firm that sells a product to strategic consumers sensitive to both price and quality over two periods. The firm can change its product quality and must determine its prices in both periods as well as whether and how to change product quality in the second period. In equilibrium, the firm would choose one strategy from the following four: simultaneous markdown and downgrade, markdown only, simultaneous markup and upgrade, and simultaneous markdown and upgrade. Such a policy structure holds irrespective of whether the firm is patient. However, the policy set shrinks when the marginal cost changes from quadratic to linear in quality and expands when customer types are uncertain in the sense that the firm is not certain about the upper bound of the support of the customer type. In the latter, the equilibrium policy is same when the uncertainty is the highest as when uncertainty is absent. [ABSTRACT FROM AUTHOR]
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- 2020
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12. Application of Fe3O4@MIL-100 (Fe) core-shell magnetic microspheres for evaluating the sorption of organophosphate esters to dissolved organic matter (DOM).
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Pang, Long, Yang, Peijie, Yang, Huiqiang, Ge, Liming, Xiao, Jingwen, and Zhou, Yifan
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DISSOLVED organic matter , *POLLUTANTS , *BIOAVAILABILITY , *POROSITY , *MAGNETIC fields - Abstract
Organophosphate esters (OPEs) are widely used as flame retardants and plasticizers in many products and materials. Because of the potential biologic toxicity on human beings, OPEs are regarded as a class of emerging pollutants. Dissolved organic matters (DOM) have significant effects on the bioavailability and toxicity of the pollutants in the environment. Negligible-depletion solid-phase microextraction (nd-SPME) is an efficient way for measuring the freely dissolved pollutants but suffers from long equilibrium time. Metal-organic frameworks (MOFs) are a class of porous crystalline materials with unique properties such as high pore volume, regular porosity, and tunable pore size, being widely used for the extraction of various organic compounds. Here we developed a novel method for quick determination the sorption coefficients of OPEs to DOM in aquatic phase using Fe 3 O 4 @MIL-100 (Fe) core-shell magnetic microspheres. The mesoporous structures of the as-synthesized microspheres hindered the extraction of OPEs which associated with humic acid due to the volume exclusion effect. However, the freely dissolved OPEs can access into the mesoporous and then were extracted by MIL-100 (Fe). Due to the small pore size (4.81 nm), large surface area (141 m 2 g −1 ), high pore volume (0.17 g 3 g −1 ), and ultra-thin MOFs layers, Fe 3 O 4 @MIL-100 (Fe) core-shell magnetic microspheres have large contact area for the analytes in aqueous phase and therefore the diffusion distance was largely shortened. Besides, the microspheres can be collected conveniently after the extraction process by applying a magnetic field. Compared to the nd-SPME method with 35 h equilibration time ( t 90% ), the proposed method for these studied OPEs only need 24 min to achieve equilibration. The sorption coefficients (log K DOC ) of the OPEs to humic acid were ranged from 3.84–5.28, which were highly consistent with the results by using polyacrylate-coated fiber and polydimethylsiloxane-coated fiber with nd-SPME. [ABSTRACT FROM AUTHOR]
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- 2018
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13. A scalable field study using leaves as a novel passive air sampler to evaluate the potential source of organophosphate esters in street dust.
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Pang, Long, Huang, Ziling, Yang, Huiqiang, Pang, Rong, Wu, Mingkai, and Jin, Baodan
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PASSIVE sampling devices (Environmental sampling) , *AIR sampling apparatus , *DUST , *ATMOSPHERIC deposition , *TRIBUTYL phosphate , *PLASTICIZERS , *MINERAL dusts - Abstract
Organophosphate esters (OPEs) are widely used as flame retardants and plasticizers in industrial and commercial products. It is generally believed that OPEs in street dust mainly originate from road traffic and anthropogenic activities. The influence of atmospheric deposition is still unknown. In this study, leaves were employed as a novel passive air sampler to collect particle matters (PM) in 12 cities in the central province of Henan, China. Similar compositional profiles of OPEs were found in street dust and PM samples. The concentrations of individual OPEs in PM were 1–4 times higher than in street dust. Chlorinated OPEs concentration in PM shows a moderate correlation (r 2 = 0.538, p < 0.01) with that in street dust. The concentration of alkyl OPEs in PM has a high correlation (r 2 = 0.843, p < 0.01) with that in street dust. No significant correlation (r 2 = 0.133, p = 0.132) was found on the aryl OPEs concentrations between street dust and PM. Spearman correlation reveals that the emission sources of tricresyl phosphate (TCrP) and triethyl phosphate (TEP) may be different from other OPEs in dust and PM samples. Principle component analysis (PCA) provides an appropriate explanation that tris (2-chloroethyl) phosphate (TCEP), triphenyl phosphate (TPhP), tris (chloropropyl) phosphate (TCPP), tributyl phosphate (TnBP), and TEP in street dust and PM may be emitted from the same sources, suggesting that PM has a significant influence on the occurrence of OPEs in street dust. The estimated dry deposition fluxes of particle-bound OPEs show a significant correlation (R 2 = 0.969, p < 0.01) with OPEs concentrations in street dust, revealing that the input of atmospheric deposition could be a major source of OPEs in street dust. [Display omitted] • Spatial phytosampling was used to study the potential source of OPEs in street dust. • Leaves were used as passive sampler for comparative applications. • Most OPEs in PM had positive correlation with those in the street dust. • The input of atmospheric deposition is a major source of OPEs in street dust. [ABSTRACT FROM AUTHOR]
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- 2023
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14. The gas phase retention volume behavior of organophosphate esters on polyurethane foam.
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Pang, Long, Zhang, Yanyan, Yang, Huiqiang, Zhang, Meijuan, Huang, Ziling, Wang, Haozhao, and Jin, Baodan
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RF values (Chromatography) , *URETHANE foam , *HEATS of vaporization , *POLYCYCLIC aromatic hydrocarbons , *SUBCOOLED liquids , *ESTERS , *VAPORIZATION - Abstract
In this study, the gas-phase retention volume behavior of four highly volatile organophosphate esters (OPEs) on polyurethane foam (PUF) was studied using a frontal chromatogram. The breakthrough volumes (V B) of trimethyl phosphate (TMP), triethyl phosphate (TEP), tripropyl phosphate (TPrP), and tri-n-butyl phosphate (TnBP) were 0.33, 0.59, 10.5, and 32.4 m3, respectively. A significant negative correlation was found between the logarithm value of V B and the subcooled liquid vapor pressure (P L) with an r 2 of 0.905, indicating that the vapor penetration depends on both the volatility and total air volume. The enthalpy of desorption and vaporization (Δ H S −Δ H V) showed a significant difference between the tested OPEs and polycyclic aromatic hydrocarbons (PAHs), revealing that the strength of the sorption interaction of the tested OPEs vapor on PUF should be different from that of PAHs. The PUF-air partition coefficients (K PUF-air) of the tested OPEs ranged from 4.3 to 8.1, which were lower than those of three-to four-ring PAHs (7.02–10.2) and organochlorines (8.01–9.72), revealing that the partition of highly volatile OPEs on PUF is lower than that of low-volatile compounds. The PUF/XAD cartridge improved the absorption efficiency of the tested OPEs; however, its sorptive capacity was still limited. [Display omitted] • The breakthrough volumes of four high volatile OPEs on PUF column were determined by frontal chromatograms. • The breakthrough volumes of the tested OPEs are much lower than three to four ring PAHs. • There are significant differences in the sorption interaction on PUF between the tested OPEs and low volatile compounds. • XAD resins can improve the sorptive capacity for high volatile OPEs. [ABSTRACT FROM AUTHOR]
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- 2022
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15. A state-of-art review on the redox activity of persistent free radicals in biochar.
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Xie, Jia, Latif, Junaid, Yang, Kangjie, Wang, Zhiqiang, Zhu, Lang, Yang, Huiqiang, Qin, Jianjun, Ni, Zheng, Jia, Hanzhong, Xin, Wang, and Li, Xing
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FREE radicals , *BIOCHAR , *ELECTRON paramagnetic resonance , *OXIDATION-reduction reaction , *REACTIVE oxygen species , *METAL defects - Abstract
• •The identification and determination methods of biochar-PFRs were outlined. • •The redox activity of biochar-PFRs was discussed. • •The consumption and generation mechanism of biochar-PFRs were summarized in detail. • •The dilemma of evaluating the redox activity of biochar-PFRs was pointed out. • •Strategies of determining the redox activity of biochar-PFRs were proposed. Biochar-bound persistent free radicals (biochar-PFRs) attract much attention because they can directly or indirectly mediate the transformation of contaminants in large-scale wastewater treatment processes. Despite this, a comprehensive top-down understanding of the redox activity of biochar-PFRs, particularly consumption and regeneration mechanisms, as well as challenges in redox activity assessment, is still lacking. To tackle this challenge, this review outlines the identification and determination methods of biochar-PFRs, which serve as a prerequisite for assessing the redox activity of biochar-PFRs. Recent developments concerning biochar-PFRs are discussed, with a main emphasis on the reaction mechanisms (both non-free radical and free radical pathways) and their effectiveness in removing contaminants. Importantly, the review delves into the mechanism of biochar-PFRs regeneration, triggered by metal cations, reactive oxygen species, and ultraviolet radiations. Furthermore, this review thoroughly explores the dilemma in appraising the redox activity of biochar-PFRs. Components with unpaired electrons (particular defects and metal ions) interfere with biochar-PFRs signals in electron paramagnetic resonance spectra. Scavengers and extractants of biochar-PFRs also inevitably modify the active ingredients of biochar. Based on these analyses, a practical strategy is proposed to precisely determine the redox activity of biochar-PFRs. Finally, the review concludes by presenting current gaps in knowledge and offering suggestions for future research. This comprehensive examination aims to provide new and significant insights into the redox activity of biochar-PFRs. [Display omitted] [ABSTRACT FROM AUTHOR]
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- 2024
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16. A novel amino acid site closely associated with the neurovirulence of live, attenuated Japanese encephalitis vaccine (SA14-14-2 strain).
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Yang, Huan, Fan, Fengming, Liu, Lina, Liu, Jie, Sun, Yan, Xie, Anping, Shi, Xiaoling, Liu, Li, Yu, Yongxin, Li, Yuhua, Ge, Yonghong, Zeng, Xianwu, and Yang, Huiqiang
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ANTISENSE DNA , *JAPANESE B encephalitis , *JAPANESE encephalitis viruses , *AMINO acids , *AMINO acid residues , *VACCINES - Abstract
• Mutation of 244-site (G → E) enhances the virulence of JEV SA14-14-2 in mice. • JEV E244 (G → E) exhibits different virulence in the context of JE vaccine. • Minor mutations in vaccine cannot be detected by Sanger sequencing. • Minor variants in vaccine do not develop to the dominant population. Japanese encephalitis (JE) poses a serious threat to the world's public health yet without a cure, the only way to prevent Japanese encephalitis virus (JEV) infection is vaccination. Live attenuated vaccine (SA14-14-2 strain) is the most widely used JE vaccine, and clinical data have confirmed its safety and effectiveness. Eight sitesassociated with virulence in the Envelope (E) protein are often the focus of quality control of JE vaccine. However, sequences retrieved from NCBI, as well as our previous results showed that the wild strain SA14 may harbor two different amino acids at amino acid residue 244 of the E glycoprotein (E244), and it may be related to virulence. In this study, we introduced a single mutation at nt1708 (G → A) in the full-length cDNA clone of SA14-14-2, replacing a Gly with Glu at amino acid residue 244 of the E glycoprotein, and successfully constructed the mutant virus (JEV E244). JEV E244 exhibited a similar plaque morphology and growth characteristics to JEV SA14-14-2 in cell culture. However, it had lethal neurovirulence in mice and could enter the brain following intraperitoneal inoculation. Moreover, the virulence of JEV E244 in the context of vaccine in mice is significantly different from that of the JEV E244 alone. These results suggested that E244 site should be included in the assessment of the genetic stability of the attenuated JE vaccine. The detection of minor mutations in vaccine population and influence on the safety of vaccine is discussed. [ABSTRACT FROM AUTHOR]
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- 2020
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17. Toxic effects and primary source of the aged micro-sized artificial turf fragments and rubber particles: Comparative studies on laboratory photoaging and actual field sampling.
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Xie, Linyang, Zhu, Kecheng, Jiang, Wenjun, Lu, Haodong, Yang, Huiqiang, Deng, Yongxi, Jiang, Yuanren, and Jia, Hanzhong
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POISONS , *SYNTHETIC sporting surfaces , *POLYCYCLIC aromatic hydrocarbons , *REACTIVE oxygen species , *HEAVY metals , *RUBBER , *CHEMICAL plants - Abstract
[Display omitted] • MATF and MRP enriched substantial heavy metals and PAHs from the environment. • MATF and MRP from actual artificial turf had significantly higher cytotoxicity. • EPFRs and ROS had limited contributions to the cytotoxicity of aged MATF and MRP. • Heavy metals and PAHs played important roles in the toxicity of MATF and MRP. Numerous micro-sized artificial turf fragments (MATF) and rubber particles (MRP) are generated and accumulated during the use of the artificial playing field. However, attention has rarely been paid to the potential toxic effects of MATF and MRP on sportsmen. In this study, the active components and chemical composition of aged MATF and MRP derived from laboratory photoaging and actual field sampling were detected, and their effects on cytotoxicity were examined correspondingly. Laboratory photoaging significantly increased environmental persistent free radicals (EPFRs), reactive oxygen species (ROS) abundances and oxidative potential (OP) levels on MATF and MRP, but they have limited cytotoxicity. Unfortunately, in the actual field, aged MATF and MRP with higher heavy metals and polycyclic aromatic hydrocarbons (PAHs) contents exhibited markedly higher cytotoxicity with the survival rate of cells of 78 % and 26 % (p < 0.05), although they had lower EPFRs and ROS yields. Correlation analysis revealed that the cell viability was closely linked to heavy metals of MATF (p < 0.05), and to organic hydroperoxide (OHP), PAHs and heavy metals of MRP (p < 0.05). By systematically considering the above results, heavy metals and PAHs enriched on MATF and MRP from the surrounding environment played the important role in the cytotoxicity, which was different from conventional perspectives. Our findings demonstrate that MATF and MRP associated with an artificial turf field contain potent mixtures of pollutants and can, therefore, be relevant yet underestimated factors contributing to the health risks. [ABSTRACT FROM AUTHOR]
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- 2022
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