1. Diterpenes, sesquiterpenes, and a C15-acetogenin from the marine red alga Laurencia mariannensis.
- Author
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Ji NY, Li XM, Li K, Ding LP, Gloer JB, and Wang BG
- Subjects
- Acetogenins chemistry, Acetogenins pharmacology, Anti-Bacterial Agents chemistry, Anti-Bacterial Agents pharmacology, Antifungal Agents chemistry, Antifungal Agents pharmacology, Aspergillus niger drug effects, Candida albicans drug effects, China, Diterpenes chemistry, Diterpenes pharmacology, Escherichia coli drug effects, Hydrocarbons, Brominated chemistry, Hydrocarbons, Brominated pharmacology, Marine Biology, Microbial Sensitivity Tests, Molecular Structure, Sesquiterpenes chemistry, Sesquiterpenes pharmacology, Staphylococcus aureus drug effects, Acetogenins isolation & purification, Anti-Bacterial Agents isolation & purification, Antifungal Agents isolation & purification, Diterpenes isolation & purification, Hydrocarbons, Brominated isolation & purification, Laurencia chemistry, Sesquiterpenes isolation & purification
- Abstract
In addition to 10 known compounds (7- 16), one new brominated diterpene, 10-hydroxykahukuene B (1), two new sesquiterpenes, 9-deoxyelatol (2) and isodactyloxene A (3), one new brominated C 15-acetogenin, laurenmariallene (4), and two new naturally occurring halogenated sesquiterpenes (5 and 6) that were previously obtained as intermediates in a biomimetic synthetic study of rhodolaureol and rhodolauradiol have been isolated and identified from the organic extract of the marine red alga Laurencia mariannensis. The structures of these compounds were established by spectroscopic methods. The antibacterial and antifungal activities of new compounds 1-4 were evaluated.
- Published
- 2007
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