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ObjectiveThis study aimed to investigate the diagnostic value of luteinizing hormone (LH) basal values and sex hormone-binding globulin (SHBG) for rapidly progressive central precocious puberty (RP-CPP).MethodsA total of 121 girls presenting with secondary sexual characteristics were selected from the Department of Pediatric Endocrinology, Lianyungang Clinical Medical College of Nanjing Medical University, from May 2021 to June 2023. The children were followed up for 6 months and were divided into three groups: RP-CPP group (n=40), slowly progressive central precocious puberty (SP-CPP) group (n=40), and premature thelarche (PT) group (n=41). The differences in LH basal values and SHBG among girls in the three groups were compared. ROC curves were drawn to analyze the value of LH basal values and SHBG in identifying RP-CPP.ResultsSignificant differences were observed in age, height, predicted adult height (PAH), weight, body mass index (BMI), bone age (BA), BA-chronological age (CA), LH basal, LH peak, FSH basal, LH peak/FSH peak, estradiol (E2), testosterone, and SHBG levels between the RP-CPP group and the SP-CPP and PT groups (P < 0.05). The LH basal value in the RP-CPP group was higher than that in the SP-CPP group and the PT group, while SHBG levels were lower than in the latter two groups, and these differences were statistically significant (P < 0.05). When the LH basal value was ≥0.58 IU/L and SHBG was ≤58.79 nmol/L, the sensitivity for diagnosing RP-CPP was 77.5% and 67.5%, and the specificity was 66.7% and 74.1%.ConclusionDetection of basal LH and SHBG levels allows for early diagnosis of the progression of central precocious puberty.

Objective: This study aimed to investigate the diagnostic value of luteinizing hormone (LH) basal values and sex hormone-binding globulin (SHBG) for rapidly progressive central precocious puberty (RP-CPP). Methods: A total of 121 girls presenting with secondary sexual characteristics were selected from the Department of Pediatric Endocrinology, Lianyungang Clinical Medical College of Nanjing Medical University, from May 2021 to June 2023. The children were followed up for 6 months andwere divided into three groups: RP-CPP group (n=40), slowly progressive central precocious puberty (SP-CPP) group (n=40), and premature thelarche (PT) group (n=41). The differences in LH basal values and SHBG among girls in the three groups were compared. ROC curves were drawn to analyze the value of LH basal values and SHBG in identifying RP-CPP. Results: Significant differences were observed in age, height, predicted adult height (PAH), weight, body mass index (BMI), bone age (BA), BA-chronological age (CA), LH basal, LH peak, FSH basal, LH peak/FSH peak, estradiol (E2), testosterone, and SHBG levels between the RP-CPP group and the SP-CPP and PT groups (P < 0.05). The LH basal value in the RP-CPP group was higher than that in the SP-CPP group and the PT group, while SHBG levels were lower than in the latter two groups, and these differenceswere statistically significant (P < 0.05). When the LH basal valuewas =0.58 IU/L and SHBG was =58.79 nmol/L, the sensitivity for diagnosing RP-CPP was 77.5% and 67.5%, and the specificity was 66.7% and 74.1%. Conclusion: Detection of basal LH and SHBG levels allows for early diagnosis of the progression of central precocious puberty. [ABSTRACT FROM AUTHOR]

To replace the frequent and laborsome manual label feeding in the cigarette packing process, an automatic label feeding system was designed. The system mainly consists of a positioning and picking device, a kraft paper cutting and reclaiming device, a lifting and buffering device, an overhead conveyor, and a visual label hopper. The positioning and picking device uses a collaborative robot and a 3D industrial camera to complete the accurate positioning and automatic picking of label stacks. According to the results of finite element analysis, the thickness of the cutter in the kraft paper cutting and reclaiming device is determined to be 0.7 mm with a blade angle of 15°. The unpacked label stacks are lifted and stored in the buffering device temporarily, prior to entering the visual label hopper via the overhead conveyor. The automatic label feeding system was tested on a ZB25 packer in Shifang Cigarette Factory. The results showed that the average feeding labor time was reduced from 2 hours/shift to 0. This technology supports the promotion of automation of packing equipment. [ABSTRACT FROM AUTHOR]

The rheological, physicomechanical, and thermomechanical properties of the binders based on an ED-20 epoxy resin and KhT-152 B, Etal-450, and Iso-MTHPA curing agents have been studied. The rheological properties of binders are practically comparable. The KhT-152 B binder-based compound exhibited the highest durability. The Iso-MTHPA based binder exhibits the highest tensile strength among all studied compounds. The studied binders are comparable in terms of thermomechanical properties, and their glass-transition temperature is 100–110°C. [ABSTRACT FROM AUTHOR]