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2. Evaluation of Dried Blood and Cerebrospinal Fluid Filter Paper Spots for Storing and Transporting Clinical Material for the Molecular Diagnosis of Invasive Meningococcal Disease.
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Kwambana-Adams, Brenda A., Clark, Stephen A., Tay, Nicole, Agbla, Schadrac, Chaguza, Chrispin, Kagucia, Eunice W., Borrow, Ray, and Heyderman, Robert S.
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MENINGOCOCCAL infections , *FILTER paper , *MOLECULAR diagnosis , *CEREBROSPINAL fluid examination , *CEREBROSPINAL fluid , *NEISSERIA meningitidis , *NUCLEOTIDE sequencing , *WHOLE genome sequencing - Abstract
To improve the storage and transport of clinical specimens for the diagnosis of Neisseria meningitidis (Nm) infections in resource-limited settings, we have evaluated the performance of dried blood spot (DBS) and dried cerebrospinal fluid spot (DCS) assays. DBS and DCS were prepared on filter paper from liquid specimens previously tested for Nm in the United Kingdom. Nm was detected and genogrouped by real-time PCR performed on crude genomic DNA extracted from the DBS (n = 226) and DCS (n = 226) specimens. Targeted whole-genome sequencing was performed on a subset of specimens, DBS (n = 4) and DCS (n = 6). The overall agreement between the analysis of liquid and dried specimens was (94.2%; 95% CI 90.8–96.7) for blood and (96.4%; 95% CI 93.5–98.0) for cerebrospinal fluid. Relative to liquid specimens as the reference, the DBS and DCS assays had sensitivities of (89.1%; 95% CI 82.7–93.8) and (94.2%; 95% CI 88.9–97.5), respectively, and both assays had specificities above 98%. A genogroup was identified by dried specimen analysis for 81.9% of the confirmed meningococcal infections. Near full-length Nm genome sequences (>86%) were obtained for all ten specimens tested which allowed determination of the sequence type, clonal complex, presence of antimicrobial resistance and other meningococcal genotyping. Dried blood and CSF filter spot assays offer a practical alternative to liquid specimens for the molecular and genomic characterisation of invasive meningococcal diseases in low-resource settings. [ABSTRACT FROM AUTHOR]
- Published
- 2022
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3. Developing a disease-specific patient reported outcome measure to enhance understanding of the lived experiences of ANCA associated vasculitis: A protocol paper.
- Author
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Floyd, Lauren, Dhaygude, Ajay, Mitra, Sandip, and Rowland, Christine
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- *
PATIENT reported outcome measures , *PATIENT experience , *RENAL replacement therapy , *ANTINEUTROPHIL cytoplasmic antibodies , *PATIENTS' attitudes - Abstract
Anti-neutrophil cytoplasmic antibody (ANCA) associated vasculitis (AAV) is a chronic, relapsing-remitting condition associated with increased morbidity. Previous research has shown patients with AAV report high levels of fatigue, pain, depression and anxiety. Over recent years successful work has been carried out to improve clinical outcomes, resulting in reduced mortality and end stage kidney disease (ESKD). Despite this, little work has been done to better understand the role of the patient within this condition. The prevalence of AAV is increasing and to date, there is a shortage of specific tools that assess and measure key features relating to patient reported outcomes (PROs). This protocol details how we can better understand the lived experiences of those with AAV through the development of a disease specific, patient reported outcome measure (PROM), to be used in clinic practice. This will allow us to recognise and validate PROs and the impact the disease and its treatment has on patients' health related quality of life (HRQoL). In addition, we aim to identify potential differences in PRO's between demographics, organ involvement and treatment subgroups in AAV as well as outcomes relating to the patient experience. Patients from a single centre in the UK will be recruited to take part in the exploratory qualitative study which will include focus groups and semi-structured interviews. The inclusion criteria comprise anyone with a diagnosis of AAV and willing to participate, including those who have active or relapsing disease, those are economically active, unemployed, retired and patients receiving renal replacement therapy. The aim of the project is to identify key issues patients experience in relation to their disease and its management and how these can be better assessed in a new PROM developed for use in the clinic setting. This will enable better delivery of individualised care and inform shared decision making, while also serving as a platform for future research looking at PROs in other glomerulonephritides. [ABSTRACT FROM AUTHOR]
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- 2024
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4. "The Will to Survive": The Lives of Young People with "No Papers" in the United Kingdom.
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Deveci, Yeṣim
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YOUNG adults , *WELL-being , *RESEARCH personnel - Abstract
This article considers how undocumented youth in the UK survive and construct their everyday lives in precarious circumstances. Drawing on multiple in-depth narrative interviews with (n = 7) undocumented youth, I illustrate how these young people focus on the future and engage in purposeful activities as a way of enduring the everyday challenges of living with no papers. I reflect on the relationships, which young people draw on to enable them to endure adversity and rebuild their everyday lives. I conclude that the presence of love and community is critical for young people's survival, safety and wellbeing, and I suggest how practitioners and researchers might make use of these findings. [ABSTRACT FROM AUTHOR]
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- 2024
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5. High stakes. Commentary on the 2023 United Kingdom government white paper on gambling reform.
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Rogers J, Roberts A, Sharman S, Dymond S, Ludvig EA, and Tunney RJ
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- Humans, Government, Advertising, United Kingdom, Gambling
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- 2023
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6. Management of Impacted Fetal Head at Caesarean Birth: Scientific Impact Paper No. 73 (June 2023).
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Cornthwaite, Katie, Bahl, Rachna, Winter, Cathy, Wright, Alison, Kingdom, John, Walker, Kate F., Tydeman, Graham, Briley, Annette, Schmidt‐Hansen, Mia, and Draycott, Tim
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BRAIN injuries , *PENILE prostheses , *INFANTS , *CLINICAL prediction rules , *PELVIS , *UTERUS - Abstract
Plain language summary: Over one‐quarter of women in the UK have a caesarean birth (CB). More than one in 20 of these births occurs near the end of labour, when the cervix is fully dilated (second stage). In these circumstances, and when labour has been prolonged, the baby's head can become lodged deep in the maternal pelvis making it challenging to deliver the baby. During the caesarean birth, difficulty in delivery of the baby's head may result – this emergency is known as impacted fetal head (IFH). These are technically challenging births that pose significant risks to both the woman and baby. Complications for the woman include tears in the womb, serious bleeding and longer hospital stay. Babies are at increased risk of injury including damage to the head and face, lack of oxygen to the brain, nerve damage, and in rare cases, the baby may die from these complications. Maternity staff are increasingly encountering IFH at CB, and reports of associated injuries have risen dramatically in recent years. The latest UK studies suggest that IFH may complicate as many as one in 10 unplanned CBs (1.5% of all births) and that two in 100 babies affected by IFH die or are seriously injured. Moreover, there has been a sharp increase in reports of babies having brain injuries when their birth was complicated by IFH. When an IFH occurs, the maternity team can use different approaches to help deliver the baby's head at CB. These include: an assistant (another obstetrician or midwife) pushing the head up from the vagina; delivering the baby feet first; using a specially designed inflatable balloon device to elevate the baby's head and/or giving the mother a medicine to relax the womb. However, there is currently no consensus for how best to manage these births. This has resulted in a lack of confidence among maternity staff, variable practice and potentially avoidable harm in some circumstances. This paper reviews the current evidence regarding the prediction, prevention and management of IFH at CB, integrating findings from a systematic review commissioned from the National Guideline Alliance. [ABSTRACT FROM AUTHOR]
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- 2023
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7. The UK Gambling White Paper: comments on implementation and timing.
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Chamberlain SR, Ioannidis K, and Bowden-Jones H
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- Humans, United Kingdom epidemiology, Gambling diagnosis, Gambling epidemiology
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- 2023
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8. Multidisciplinary paper on patient blood management in cardiothoracic surgery in the UK: perspectives on practice during COVID-19.
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Al-Attar N, Gaer J, Giordano V, Harris E, Kirk A, Loubani M, Meybohm P, Sayeed R, Stock U, Travers J, and Whiteman B
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- Humans, State Medicine, Blood Transfusion, United Kingdom, COVID-19, Specialties, Surgical
- Abstract
The coronavirus (COVID-19) pandemic disrupted all surgical specialties significantly and exerted additional pressures on the overburdened United Kingdom (UK) National Health Service. Healthcare professionals in the UK have had to adapt their practice. In particular, surgeons have faced organisational and technical challenges treating patients who carried higher risks, were more urgent and could not wait for prehabilitation or optimisation before their intervention. Furthermore, there were implications for blood transfusion with uncertain patterns of demand, reductions in donations and loss of crucial staff because of sickness and public health restrictions. Previous guidelines have attempted to address the control of bleeding and its consequences after cardiothoracic surgery, but there have been no targeted recommendations in light of the recent COVID-19 challenges. In this context, and with a focus on the perioperative period, an expert multidisciplinary Task Force reviewed the impact of bleeding in cardiothoracic surgery, explored different aspects of patient blood management with a focus on the use of haemostats as adjuncts to conventional surgical techniques and proposed best practice recommendations in the UK., (© 2023. The Author(s).)
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- 2023
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9. Methods for living guidelines: early guidance based on practical experience. Paper 2: consumer engagement in living guidelines.
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Synnot A, Hill K, Davey J, English K, Whittle SL, Buchbinder R, May S, White H, Meredith A, Horton E, Randall R, Patel A, O'Brien S, and Turner T
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- Humans, Australia, United Kingdom, Patients, Caregivers
- Abstract
Objectives: To describe and reflect on the consumer engagement approaches used in five living guidelines from the perspectives of consumers (i.e., patients, carers, the public, and their representatives) and guideline developers., Study Design and Setting: In a descriptive report, we used a template to capture engagement approaches and the experiences of consumers and guideline developers in living guidelines in Australia and the United Kingdom. Responses were summarized using descriptive synthesis., Results: One guideline used a Consumer Panel, three included two to three consumers in the guideline development group, and one did both. Much of our experience was common to all guidelines (e.g., consumers felt welcomed but that their role initially lacked clarity). We identified six challenges and opportunities specific to living guidelines: managing the flow of work; managing engagement in online environments; managing membership of the panel; facilitating more flexibility, variety and depth in engagement; recruiting for specific skills-although these can be built over time; developing living processes to improve; and adapting consumer engagement together., Conclusion: Consumer engagement in living guidelines should follow established principles of consumer engagement in guidelines. Conceiving the engagement as living, underpinned by a living process evaluation, allows the approach to be developed with consumers over time., (Copyright © 2023 The Authors. Published by Elsevier Inc. All rights reserved.)
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- 2023
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10. Worth the paper it's written on? A cross-sectional study of Medical Certificate of Stillbirth accuracy in the UK.
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Rimmer MP, Henderson I, Parry-Smith W, Raglan O, Tamblyn J, Heazell AEP, and Higgins LE
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- Infant, Newborn, Female, Pregnancy, Humans, Cross-Sectional Studies, Fetal Death etiology, Gestational Age, United Kingdom epidemiology, Stillbirth epidemiology, Placenta
- Abstract
Background: The Medical Certificate of Stillbirth (MCS) records data about a baby's death after 24 weeks of gestation but before birth. Major errors that could alter interpretation of the MCS were widespread in two UK-based regional studies., Methods: A multicentre evaluation was conducted, examining MCS issued 1 January 2018 to 31 December 2018 in 76 UK obstetric units. A systematic case-note review of stillbirths was conducted by Obstetric and Gynaecology trainees, generating individual 'ideal MCSs' and comparing these to the actual MCS issued. Anonymized central data analysis described rates and types of error, agreement and factors associated with major errors., Results: There were 1120 MCSs suitable for assessment, with 126 additional submitted data sets unsuitable for accuracy analysis (total 1246 cases). Gestational age demonstrated 'substantial' agreement [K = 0.73 (95% CI 0.70-0.76)]. Primary cause of death (COD) showed 'fair' agreement [K = 0.26 (95% CI 0.24-0.29)]. Major errors [696/1120; 62.1% (95% CI 59.3-64.9%)] included certificates issued for fetal demise at <24 weeks' gestation [23/696; 3.3% (95% CI 2.2-4.9%)] or neonatal death [2/696; 0.3% (95% CI 0.1-1.1%)] or incorrect primary COD [667/696; 95.8% (95% CI 94.1-97.1%)]. Of 540/1246 [43.3% (95% CI 40.6-46.1%)] 'unexplained' stillbirths, only 119/540 [22.0% (95% CI 18.8-25.7%)] remained unexplained; the majority were redesignated as either fetal growth restriction [FGR: 195/540; 36.1% (95% CI 32.2-40.3%)] or placental insufficiency [184/540; 34.1% (95% CI 30.2-38.2)]. Overall, FGR [306/1246; 24.6% (95% CI 22.3-27.0%)] was the leading primary COD after review, yet only 53/306 [17.3% (95% CI 13.5-22.1%)] FGR cases were originally attributed correctly., Conclusion: This study demonstrates widespread major errors in MCS completion across the UK. MCS should only be completed following structured case-note review, with particular attention on the fetal growth trajectory., (© The Author(s) 2022. Published by Oxford University Press on behalf of the International Epidemiological Association.)
- Published
- 2023
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11. 'As straight as they come': Expressions of masculinities within digital sex markets.
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Rand, Helen M
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INTERNET marketing ,QUEER theory ,MASCULINITY ,GENDER identity ,ELECTRONIC paper ,DATA privacy ,MASCULINE identity ,DESIRE - Abstract
The research presented in this paper supports claims by feminists and queer theorists that there are numerous and diverse sex/gender/desire categories (Bem, 1995). Taken from a broader digital ethnography of digital sex markets in the United Kingdom, the findings are based on ten in-depth interviews with those who identified as men or 'gender flexible' and who buy and/or sell sex within digital markets. The participants featured in this paper used digital sex markets as a space to explore and express non-normative/subversive sexual and gender identities. Yet for many of them, these subversive acts were bounded by the market, so they were able to uphold masculine heterosexual identities outside of sex markets. The relative privacy of digital sex markets empowered them to maintain heterosexist power, reducing the social risks of stigmatisation and ostracisation associated with subversive sexual and gender identities. The thematic analysis revealed the limitations of heteronormative and homonormative labels and assumptions of sex work relations, thus, prompting the need to write this paper. Framing sex markets in narrow binary terms, as either homosexual or heterosexual markets, or research participants as customers or workers do not reflect the fluidity and diversity evident in this small yet revealing sample. The study shows multiple and fluid expressions of sex/gender/desire; and a duality in market roles as workers and/or customers amongst men engaged in digital sex markets. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
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12. Microfibrillated cellulose films for mending translucent paper: an assessment of film preparation and treatment application options.
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Henniges, Ute, Angelova, Lora, Schwoll, Sonja, Smith, Holly, and Brückle, Irene
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JAPANESE films ,NATIONAL archives ,OPTICAL properties - Abstract
Copyright of Journal of the Institute of Conservation is the property of Routledge and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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- 2022
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13. Impact of sampling and data collection methods on maternity survey response: a randomised controlled trial of paper and push-to-web surveys and a concurrent social media survey.
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Harrison, Siân, Alderdice, Fiona, and Quigley, Maria A.
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RANDOMIZED controlled trials ,SOCIAL media ,ACQUISITION of data - Abstract
Background: Novel survey methods are needed to tackle declining response rates. The 2020 National Maternity Survey included a randomised controlled trial (RCT) and social media survey to compare different combinations of sampling and data collection methods with respect to: response rate, respondent representativeness, prevalence estimates of maternity indicators and cost. Methods: A two-armed parallel RCT and concurrent social media survey were conducted. Women in the RCT were sampled from ONS birth registrations and randomised to either a paper or push-to-web survey. Women in the social media survey self-selected through online adverts. The primary outcome was response rate in the paper and push-to-web surveys. In all surveys, respondent representativeness was assessed by comparing distributions of sociodemographic characteristics in respondents with those of the target population. External validity of prevalence estimates of maternity indicators was assessed by comparing weighted survey estimates with estimates from national routine data. Cost was also compared across surveys. Results: The response rate was higher in the paper survey (n = 2,446) compared to the push-to-web survey (n = 2,165)(30.6% versus 27.1%, difference = 3.5%, 95%CI = 2.1–4.9, p < 0.0001). Compared to the target population, respondents in all surveys were less likely to be aged < 25 years, of Black or Minority ethnicity, born outside the UK, living in disadvantaged areas, living without a partner and primiparous. Women in the social media survey (n = 1,316) were less representative of the target population compared to women in the paper and push-to-web surveys. For some maternity indicators, weighted survey estimates were close to estimates from routine data, for other indicators there were discrepancies; no survey demonstrated consistently higher external validity than the other two surveys. Compared to the paper survey, the cost saving per respondent was £5.45 for the push-to-web survey and £22.42 for the social media survey. Conclusions: Push-to-web surveys may cost less than paper surveys but do not necessarily result in higher response rates. Social media surveys cost significantly less than paper and push-to-web surveys, but sample size may be limited by eligibility criteria and recruitment window and respondents may be less representative of the target population. However, reduced representativeness does not necessarily introduce more bias in weighted survey estimates. [ABSTRACT FROM AUTHOR]
- Published
- 2023
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14. Digital geographies of everyday multiculturalism: 'Let's go Nando's!'.
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Bennett, Katy, Gardner, Zoe, and De Sabbata, Stefano
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MULTICULTURALISM , *ELECTRONIC paper , *CITIES & towns , *GEOGRAPHY , *SOCIAL media - Abstract
As UK cities and towns become increasingly ethnically and culturally diverse, researchers have tuned into how people inhabit multiculturalism. Ethnographic approaches have focused on the kind of togetherness that people generate as they go about their everyday lives, observing the affective textures of interactions and happenings of the here and now in granular detail. Missing from these accounts is what crowdsourced data might add to understandings of how multicultural places are experienced. What is vital about this kind of data is that it is 'big', involving a diversity of voices similarly intent on messaging their experiences, presenting opportunities to scale up the affect of encounters and to quantify what is difficult to qualify. This paper brings Digital Geographies into conversation with research on everyday multiculturalism to examine qualitatively and quantitatively how social media use folds into and expresses various practices of sociality and connection. Our paper involves Twitter, Nando's and the city of Leicester in the UK to challenge and advance ways of understanding everyday multiculturalism in an era of global migration and ethnically complex populations. [ABSTRACT FROM AUTHOR]
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- 2023
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15. Why do health professionals need to know about the nutrition and health claims regulation? Summary of an Academy of Nutrition Sciences' Position Paper.
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Stanner, Sara, Ashwell, Margaret, and Williams, Christine M.
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HEALTH insurance reimbursement laws , *GOVERNMENT regulation , *DIET , *ORGANIZATIONAL goals , *MEDICAL protocols , *HEALTH insurance reimbursement , *INTERPROFESSIONAL relations - Abstract
The article presents the discussion on claims about the nutritional and health benefits of foods and drinks Position Paper emphasises the learnings gaining through the implementation of the European Food Safety Authority evidence‐based process for assessment of proposed claims; and main audience for the Academy's work is the nutrition science community/profession and its stakeholders.
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- 2023
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16. Bourdieu's field theory applied to the story of the UK radiography profession: A discussion paper.
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Louise McKnight K
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- Humans, United Kingdom, Radiography
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Objectives: There are many suggestions offered within the literature to decide if a job type is a profession, some using tick box type trait and characteristics analyses to compare the actions and qualities of individuals to a predefined list. However, there is no specific way to resolve what makes or defines a profession. Writers in many disciplines, including radiography, have used these different models, sometimes with conflicting results. This paper explores the use of Bourdieu's replacement of the concept of profession with that of a 'field', meaning a network of occupants with common attributes, in this case radiographers, in an attempt to resolve this issue., Findings: In the UK, radiography practitioners and professional bodies generally use the term profession to describe radiography, and this paper explores a defence of the term for radiography. Using Bourdieu's field theory not only helps define a profession, but also explains the difficulties at the boundaries of professions, and the work needed to protect a profession as a credible entity., Conclusion: This paper supports the argument that radiography is a profession when using Bourdieu's field theory. Radiography continues to work to maintain its status by increasing its symbolic capital by increasing the research output and evidence base of the profession and through role extension., Implications for Practice: Radiographers can perhaps be assured that radiography is a profession when using Bourdieu's field theory. This paper shows how theoretical frameworks and concepts from outside radiography can be used to support new ways of thinking within the profession., Competing Interests: Declarations of competing interest This article is based on a thesis successfully submitted for a Professional Doctorate of Education (EdD) at Birmingham City University which was funded by Birmingham City University., (Copyright © 2022 The College of Radiographers. Published by Elsevier Ltd. All rights reserved.)
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- 2023
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17. Diversity of authors in the British Journal of Orthodontics and Journal of Orthodontics over the last 50 years.
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Harrison, Jayne E.
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BRITISH authors ,ORTHODONTICS ,ODDS ratio ,PERSONAL names ,ELECTRONIC information resource searching - Abstract
Aims: To explore any changes in the perceived gender and affiliation of first authors of papers published in the British Journal of Orthodontics (BJO) and Journal of Orthodontics (JO), over the last 50 years. Methods: Electronic hand searches of the BJO and JO from 1973 to 2021, were undertaken to identify research and clinical papers published the first volume of the BJO (1973-74) and then the first two volumes of each subsequent decade i.e. 1980-81; 1990-91 to 2020-21. Articles such as Editorials, Product Updates and Abstract summaries, were excluded. The perceived gender of the first author was identified from their forename, internet sources and/or personal knowledge, where possible. The country of the first author's affiliation was identified from the author details stated in the papers. The countries were then grouped into geographical areas. Results: A total of 385 papers were identified with a steady increase from 1973 to 2021. There was a statistically significant increase in papers published by authors who were perceived to be female (odds ratio 8.33; 95% CI 4.75, 14.64). The increase in papers published by non-UK affiliated first authors was significant (odds ratio 5.01; 95% CI 2.78, 9.02). Conclusions: The Journal has seen a significant change, over the last 50 years, in its authorship profile from nearly exclusively male, UK based authors to more than 60% of published papers having a first author who was perceived as being female and 37% originating from outside the UK. [ABSTRACT FROM AUTHOR]
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- 2023
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18. Institutional choice among medical applicants: a profile paper for The United Kingdom Medical Applicant Cohort Study (UKMACS) prospective longitudinal cohort study.
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Harrison D, McManus IC, Rees EL, and Woolf K
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- Career Choice, Cohort Studies, Cross-Sectional Studies, Humans, Longitudinal Studies, Prospective Studies, Schools, Medical, United Kingdom, School Admission Criteria, Students, Medical
- Abstract
Purpose: To generate a large cohort of those in 2019 seriously considering applying to study Medicine, collecting data on a range of socioeconomic and other demographic factors that influence choice of medical schools and to link to other datasets to form a longitudinal study of progress through medical school and careers in medicine., Design: Cross-sectional questionnaire studies, part of the longitudinal UK Medical Applicant Cohort Study (UKMACS)., Setting: UK medical school admissions in 2020., Participants: UK residents aged 16+ and seriously considering applying to study Medicine. The cohort was primarily drawn from those registering in 2019 for the U(K)CAT (University Clinical Aptitude Test (formerly the UK Clinical Aptitude Test)) with additional potential applicants responding to an open call. Participants consented to their data being linked within the UK Medical Education Database., Findings to Date: UKMACS Wave 1 questionnaire respondents consisted of 6391 consenting respondents from across the UK. In 2019, 14 980 of the 17 470 UK-domiciled medicine applicants were first-time applicants. The questionnaires show that many of these applicants have a need for more help and guidance to make informed choices, with less advantaged groups reporting themselves as being at a disadvantage when applying due to limited understanding of information and limited access to guidance to enable informed and effective decision-making., Future Plans: To link the cohort with successive Universities and Colleges Admissions Service and other datasets to analyse outcomes of applications and establish national longitudinal evidence to understand how medical choices are made and how they impact on educational, career and workforce outcomes., Competing Interests: Competing interests: None declared., (© Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.)
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- 2022
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19. Preventing unscheduled hospitalisations from asthma: a retrospective cohort study using routine primary and secondary care data in the UK (The PUSH-Asthma Study)-protocol paper.
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Simms-Williams N, Nagakumar P, Thayakaran R, Adderley N, Hotham R, Mansur A, Nirantharakumar K, and Haroon S
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- Adrenal Cortex Hormones therapeutic use, Hospitalization, Humans, Retrospective Studies, United Kingdom epidemiology, Asthma drug therapy, Asthma epidemiology, Secondary Care
- Abstract
Introduction: Asthma is the most common chronic respiratory disease in children and adults. Asthma results in significant disease-related morbidity, healthcare costs and, in some cases, death. Despite efforts through implementation of national guidelines to improve asthma care, the UK has one of the highest asthma-related morbidity and mortality rates in the western world. New approaches are necessary to prevent asthma attacks in children and adults. The objectives of this study are to assess the association between demographic and clinical factors and asthma-related hospital admissions in children and adults, describe the epidemiology of asthma phenotypes among hospital attenders, and externally validate existing asthma risk prediction models., Methods and Analysis: This is a retrospective cohort study of children and adults with asthma. Data will be extracted from the Clinical Practice Research Datalink (CPRD) Aurum database, which holds anonymised primary care data for over 13 million actively registered patients and covers approximately 19% of the UK population. The primary outcome will be asthma-related hospital admissions. The secondary outcomes will be prescriptions of short courses of oral corticosteroids (as a surrogate measure for asthma exacerbations), a composite outcome measure including hospital admissions and prescriptions of short courses of oral corticosteroids and delivery of asthma care management following hospital discharge. The primary analysis will use a Poisson regression model to assess the association between demographic and clinical risk factors and the primary and secondary outcomes. Latent class analysis will be used to identify distinct subgroups, which will further our knowledge on potential phenotypes of asthma among patients at high risk of asthma-related hospital admissions. A Concordance statistic (C-statistic) and logistic regression model will also be used to externally validate existing risk prediction models for asthma-related hospitalisations to allow for the optimal model to be identified and evaluated provide evidence for potential use of the optimal performing risk prediction model in primary care., Ethics and Dissemination: This study was approved by the CPRD Independent Scientific Advisory Committee (reference number: 21_000512). Findings from this study will be published in a peer-reviewed journal and disseminated at national and international conferences., Competing Interests: Competing interests: None declared., (© Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.)
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- 2022
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20. Measuring the online attention to business research papers: An altmetric study of selected journals with high impact factor.
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Verma, Manoj Kumar and Yuvaraj, Mayank
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- *
ALTMETRICS , *SOCIAL media in business , *BUSINESS ethics , *CITATION analysis , *KRUSKAL-Wallis Test , *STATISTICAL software - Abstract
The present study is aimed toward examining the attention received by research papers through social and electronic media in business research. In recent years, altmetrics has emerged as a complementary measure of the impact of research works besides citation analysis and bibliometrics. Using the altmetric attention score (AAS) the paper is the first research of its kind to shed light on the characteristics of 100 papers receiving the highest online attention. Various predictors of online engagement with articles in business research journals having an impact factor greater than 6 are discussed. Data was collected from the Dimensions.ai database and analyzed using R statistical software. It is found that the Journal of Business Ethics contributed maximum papers with the highest AAS followed by the Journal of Business Research. Using the Kruskal-Wallis rank-sum test it was determined that AAS in business research is dependent upon article type, topics, and journal of publication. Most of the papers in high impact factor business journals have been contributed by the authors of USA, UK and China. [ABSTRACT FROM AUTHOR]
- Published
- 2022
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21. Review Papers Examining accountability in relation to local football communities.
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Burns, John Edward and Jollands, Stephen
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SOCCER ,VALUE (Economics) ,DELIBERATION - Abstract
Purpose: Most football clubs were founded by members of the local community within which they are based. The success of a club is built on the time, effort and resources given by these locals, which is offered due to the benefits that football promises to the community in return. However, the game has increasingly been dominated by a focus on financial (monetary) value, at the expense of such benefits being delivered to the clubs' local communities. This article examines a need for deliberation over what accountability is owed by football clubs to their local communities in the context of questioning what and for whom football is for. Design/methodology/approach: This exploration is undertaken within the context of the English game, where a series of issues has resulted in the UK Government undertaking a "fan led review of football governance". The report produced by this review is analysed to understand whether the contents and recommendations enters the debate over what accountability is owed to local communities. Findings: While the UK Government's fan led review recognises the pivotal role of local communities in the formation of the English game, its focus and resulting recommendations are mostly on the financial sustainability of the clubs. The analysis demonstrates that, due to their focus on financial value, the implementation of the report's recommendations is more likely to exacerbate the underlying issues rather than resolving them. Originality/value: The call for deliberation over whether and what accountability is owed to local communities has been repeated over time. The UK Government's fan led review provided an important opportunity to engage in that deliberation. However, the dominance of financial value within football has all but silenced any call for and action regarding this. [ABSTRACT FROM AUTHOR]
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- 2024
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22. Management of children and adults with all stages of nodular lymphocyte predominant Hodgkin lymphoma - All StAGEs: A consensus-based position paper from the Hodgkin lymphoma subgroup of the UK National Cancer Research Institute.
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Shankar A, Hall GW, McKay P, Gallop-Evans E, Fielding P, and Collins GP
- Subjects
- Academies and Institutes, Adult, Child, Consensus, Humans, Lymphocytes pathology, United Kingdom epidemiology, Hodgkin Disease drug therapy, Hodgkin Disease therapy
- Abstract
A consensus statement for the management for patients of all ages with all stages of nodular lymphocyte predominant Hodgkin lymphoma (NLPHL) - All StAGEs - is proposed by representatives of the UK National Cancer Research Institute (NCRI) Hodgkin lymphoma study group and the Children's Cancer & Leukaemia Group. Based on current practices and published evidence, a consensus has been reached regarding diagnosis, staging and risk-ik7 stratified management which includes active surveillance, low- and standard-dose immunochemotherapy and radiotherapy., (© 2022 British Society for Haematology and John Wiley & Sons Ltd.)
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- 2022
- Full Text
- View/download PDF
23. Festschrift for Mike Jackson: Call for papers for a special issue of Systems Research and Behavioral Science.
- Author
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Flood, Robert L. and Midgley, Gerald
- Subjects
CRITICAL thinking ,SYSTEM analysis ,SPECIAL days - Abstract
The article announces the submission of papers about systems thinking and operational research in commemoration of the contribution of Emeritus Professor Mike Jackson.
- Published
- 2022
- Full Text
- View/download PDF
24. Evaluating misoprostol and mechanical methods for induction of labour: Scientific Impact Paper No. 68 April 2022.
- Author
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Weeks, Andrew D., Lightly, Kate, Mol, Ben W., Frohlich, Julie, Pontefract, Sarah, and Williams, Myfanwy J.
- Subjects
- *
INDUCED labor (Obstetrics) , *MISOPROSTOL , *ARTIFICIAL membranes , *DRUG standards , *DINOPROSTONE - Abstract
Plain language summary: Increasingly, births around the world are started artificially using medications or other methods. This process is known as induction of labour. As it becomes more common, methods are needed to meet the different clinical needs and birth preferences of women. Induction of labour typically includes a combination of the medication dinoprostone inserted into the vagina, artificial rupture of membranes ('releasing the waters'), and synthetic oxytocin (hormone given via a drip). This paper reviews some of the methods less commonly used for induction in the UK, namely a drug called misoprostol, which can be given orally or vaginally, and 'mechanical' methods, where labour is started by stretching the cervix (neck of the womb), most commonly with a soft silicone tube with a balloon near the tip, filled with water. Low‐dose oral misoprostol tablets are now commercially available in the UK. Other methods for labour induction are not reviewed in detail in this paper. The evidence suggests mechanical induction of labour (using a balloon catheter) and misoprostol are both at least as safe and effective as using the standard drug, dinoprostone. There is evidence to suggest a balloon catheter may reduce the chance of serious negative outcomes for babies when compared with dinoprostone, and that giving low‐dose oral misoprostol results in fewer caesarean births. Where possible and after informed consent, the method of induction of labour should be personalised to suit the individual woman, her clinical condition, and the setting in which she is giving birth. Local contexts and resources also need to be taken into account. To date, research into women's perspectives and experiences of induction of labour have been significantly lacking. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
- View/download PDF
25. The Nature of Contemporary Studies of Education: An Analysis of Articles Published in Leading Journals.
- Author
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Croll, Paul
- Subjects
AUTHORSHIP ,PUBLISHED articles ,EDUCATION research ,GLOBALIZATION ,QUALITATIVE research ,SOCIAL classes - Abstract
The article is based on a Keynote Lecture at the 2022 Colloquium of the Society for Educational Studies. It analyses the articles published in four leading journals in 2021 and compares these with the same journals 20 years earlier. Key findings include a considerable increase in authorship and multiple authorship and a very strong international dimension to authorship in current UK-based journals. Two-thirds of the papers were empirical, and by far the most common type of research design was qualitative interview studies, often of a very small-scale nature. Aspects of the teaching profession were the most common form of content, and there was also a focus on social class and multi-cultural issues. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
26. Worth the paper they are printed on? Findings from an independent evaluation of the understandability of patient information leaflets for antiseizure medications.
- Author
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Noble, Adam J., Haddad, Sara, Coleman, Niamh, and Marson, Anthony G.
- Subjects
- *
READABILITY (Literary style) , *PEOPLE with epilepsy , *PAMPHLETS , *DRUGS , *PREGABALIN , *COLLEGE students - Abstract
Objective: The Patient Information Leaflet (PIL) is an authoritative document that all people with epilepsy in the EU receive when prescribed antiseizure medication (ASM). We undertook the first independent, comprehensive assessment to determine how understandable they are. Regulators state that when patients are asked comprehension questions about them, ≥80% should answer correctly. Also, recommended is that PILs have a maximum reading requirement of US grade 8. Methods: Study 1: We obtained 140 current ASM PILs written in English. "Readability" was assessed using four tests, with and without adjustment for influence of familiar, polysyllabic words. A total of 179 online materials on epilepsy were also assessed. Study 2: Two PILs from Study 1 were randomly selected (Pregabalin Focus; Inovelon) and shown to 35 people from the UK epilepsy population. Their comprehension was assessed. Study 3: To understand whether the student population provides an accessible alternative population for future examination of ASM PILs, Study 3 was completed, using the same methods as Study 2, except that participants were 262 UK university students. Results: Study 1: No PIL had a reading level of grade 8. Median was grade 11. Adjusting for context, the PILs were still at grade 10.5. PILs for branded ASMs were most readable. PILs were no more readable than (unregulated) online materials. Study 2: Users struggled to comprehend the PILs' key messages. The eight questions asked about pregabalin were typically answered correctly by 54%. For Inovelon, it was 62%. Study 3: Most student participants comprehended the PILs' key messages. The questions about Inovelon were answered correctly by 90%; for pregabalin it was 86%. Significance: This is the first independent and comprehensive examination of ASM PILs. It found that PILs being used fail to meet recommendations and regulatory requirements and risk not being understandable to a substantial proportion of users. In finding that people from the epilepsy population differ markedly in comprehension of PILs compared to students, this study highlights the importance of completing user testing with the target population. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
- View/download PDF
27. Reporting transparency and completeness in trials: Paper 3 - trials conducted using administrative databases do not adequately report elements related to use of databases.
- Author
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Imran M, Mc Cord K, McCall SJ, Kwakkenbos L, Sampson M, Fröbert O, Gale C, Hemkens LG, Langan SM, Moher D, Relton C, Zwarenstein M, Juszczak E, and Thombs BD
- Subjects
- Canada, Databases, Factual, Humans, Randomized Controlled Trials as Topic, United Kingdom, Research Report
- Abstract
Objective: We evaluated reporting completeness and transparency in randomized controlled trials (RCTs) conducted using administrative data based on 2021 CONSORT Extension for Trials Conducted Using Cohorts and Routinely Collected Data (CONSORT-ROUTINE) criteria., Study Design and Setting: MEDLINE and the Cochrane Methodology Register were searched (2011 and 2018). Eligible RCTs used administrative databases for identifying eligible participants or collecting outcomes. We evaluated reporting based on CONSORT-ROUTINE, which modified eight items from CONSORT 2010 and added five new items., Results: Of 33 included trials (76% used administrative databases for outcomes, 3% for identifying participants, 21% both), most were conducted in the United States (55%), Canada (18%), or the United Kingdom (12%). Of eight items modified in the extension; six were adequately reported in a majority (>50%) of trials. For the CONSORT-ROUTINE modification portion of those items, three items were reported adequately in >50% of trials, two in <50%, two only applied to some trials, and one only had wording modifications and was not evaluated. For five new items, four that address use of routine data in trials were reported inadequately in most trials., Conclusion: How administrative data are used in trials is often sub-optimally reported. CONSORT-ROUTINE uptake may improve reporting., Competing Interests: Declaration of Competing Interests All authors have completed the ICJME uniform disclosure form and declare: no support from any organisation for the submitted work; no financial relationships with any organisations that might have an interest in the submitted work in the previous three years, (Copyright © 2021. Published by Elsevier Inc.)
- Published
- 2022
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28. Correctness and Completeness of Breast Cancer Diagnoses Recorded in UK CPRD Aurum and CPRD GOLD Databases: Comparison to Hospital Episode Statistics and Cancer Registry (Companion Paper 2).
- Author
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Hagberg, Katrina Wilcox, Vasilakis-Scaramozza, Catherine, Persson, Rebecca, Neasham, David, Kafatos, George, and Jick, Susan
- Subjects
CANCER diagnosis ,HOSPITAL statistics ,GOLD ,MEDICAL coding - Abstract
Purpose: To evaluate the new Clinical Practice Research Datalink (CPRD) Aurum database, we estimated 'correctness' (ie accuracy, validity) and 'completeness' (ie presence, missingness) of malignant breast cancer diagnoses recorded in CPRD Aurum compared to external linked data sources: Hospital Episode Statistics (HES) Admitted Patient Care (APC), HES Outpatient (OP), and Cancer Registry (CR), and to the previously validated CPRD GOLD.Methods: Linkage-eligible, female patients with incident malignant breast cancer diagnosis recorded in at least one study data source were selected. Correctness was the proportion of malignant breast cancer cases recorded in CPRD Aurum or GOLD who also had a diagnosis recorded in HES APC/OP (2004– 2019) or CR (2004– 2016). Completeness was estimated by identifying all malignant breast cancer diagnoses in HES APC/OP or CR and calculating the proportion with a concordant diagnosis in CPRD Aurum or GOLD.Results: Compared to HES APC/OP, there were 85,659 and 31,452 eligible patients in CPRD Aurum and GOLD, respectively. Correctness estimates were high (CPRD Aurum 83.5%, GOLD 81.7%). Compared to CR, there were 70,190 and 29,597 eligible patients in CPRD Aurum and GOLD, respectively: correctness was 89.1% for CPRD Aurum and 88.2% for GOLD. Completeness estimates for CPRD Aurum and GOLD were high (> 90%). Diagnoses were recorded in CPRD Aurum within − 7 to 74 days of those in the linked sources. Reasons for discordant diagnostic coding included presence of treatment or other clinical codes only, diagnosis coded after end of follow-up, non-malignant breast cancer in linked data, and administrative codes in lieu of diagnostic codes.Conclusion: These results indicate that correctness and completeness of malignant breast cancer diagnoses in CPRD Aurum were high and similar to CPRD GOLD. This provides confidence in use of CPRD Aurum for research purposes. Where complete case capture is important, researchers should consider linkage to HES APC or CR. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
29. Presence of Breast Cancer Information Recorded in United Kingdom Primary Care Databases: Comparison of CPRD Aurum and CPRD GOLD (Companion Paper 1).
- Author
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Hagberg, Katrina Wilcox, Vasilakis-Scaramozza, Catherine, Persson, Rebecca, Neasham, David, Kafatos, George, and Jick, Susan
- Subjects
BREAST cancer ,PRIMARY care ,MEDICAL record databases ,CANCER diagnosis ,BREAST cancer research ,GOLD ,FORCEPS - Abstract
Purpose: To evaluate the presence of data elements related to diagnosis and treatment of malignant breast cancer in CPRD Aurum compared to those in the previously validated CPRD GOLD.Methods: Females in CPRD Aurum or GOLD with a first-time code for malignant breast cancer, mastectomy, or ≥ 1 prescription for tamoxifen or aromatase inhibitors (2004– 2019) were selected. We compared the presence of the codes for breast cancer diagnosis, surgeries (mastectomy, lumpectomy), tamoxifen and aromatase inhibitor prescriptions, radiation, chemotherapy, and supporting clinical codes (suspected breast cancer, lump symptoms, biopsy, lumpectomy, cancer care, referral/visit to specialist, palliative care). Age standardized incidence rates of breast cancer diagnosis in CPRD Aurum and GOLD were calculated.Results: There were 131,936 eligible patients in CPRD Aurum and 69,102 patients in GOLD. A similar proportion of patients in CPRD Aurum and GOLD had codes for breast cancer diagnosis, mastectomy, drug prescriptions, lump, biopsy, lumpectomy, chemotherapy, and cancer and palliative care coded in their electronic record during follow-up. However, suspected breast cancer, radiation, and referral/visits to specialists were coded more frequently in patients in CPRD Aurum compared to GOLD. Age-standardized incidence rates were similar for CPRD Aurum and GOLD.Conclusion: Overall, there was consistency between data elements related to malignant breast cancer recorded in CPRD Aurum and GOLD, particularly for the most informative clinical details. These findings provide reassurance that breast cancer information recorded in CPRD Aurum is generally comparable to that recorded in the previously validated CPRD GOLD and support the use of CPRD Aurum for breast cancer research. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
30. Synthesising nutrition science into dietary guidelines for populations amidst the challenge of fake news: Summary of an Academy of Nutrition Sciences position paper.
- Author
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Williams CM, Buttriss JL, and Whelan K
- Subjects
- Evidence-Based Medicine history, Evidence-Based Medicine methods, Evidence-Based Medicine standards, Evidence-Based Medicine trends, History, 20th Century, Humans, Social Media standards, United Kingdom epidemiology, Academies and Institutes, Noncommunicable Diseases prevention & control, Nutrition Policy, Nutritional Sciences, Research Report
- Published
- 2021
- Full Text
- View/download PDF
31. Serious Funny Papers: A Contextual Examination into the Making of an Acadomic.
- Author
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Lawrence, Julian
- Subjects
- *
DIGITAL technology , *GRAPHIC novels , *COVID-19 pandemic , *ACADEMIC discourse , *COMIC books, strips, etc. - Abstract
In this academic comic (or acadomic) I reflect on impacts to the creative process when reconceptualizing and recontextualizing a comics-based research (CBR) project as an acadomic for an edited book during the Covid-19 pandemic. The lockdowns intensified computer-mediated-communication (CMC) and I am compelled by two years of virtually exclusive engagement with digital technologies to explore the impact unrestrained online activities have on my creative comics practice, on my conceptions of research, and on my experiences as a teacher. Analysis of this process and its impacts is realized through a mixed research methodology that explores the impacts of conceptualizing and making an earlier acadomic, which in turn documents a comics-based research project between university students and a national charity as they successfully collaborate on the creation of a graphic novel. I probe the boundaries of academic writing by visualizing and performing Baudrillard's theoretical violence to critique digital intensification through metaphor, semiotics, and comics. The work for this article was undertaken during the rolling pandemic lockdowns in the UK and around the world from 2020 to 2022. Academic theory and the medium of comics problematize the digital simulacrum as I action a utopian pedagogy that supports balance between traditional and digital techniques. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
- View/download PDF
32. Risk‐Reducing Salpingo‐Oophorectomy and the Use of Hormone Replacement Therapy Below the Age of Natural Menopause: Scientific Impact Paper No. 66.
- Author
-
Manchanda, R, Gaba, F, Talaulikar, V, Pundir, J, Gessler, S, Davies, M, and Menon, U
- Subjects
- *
HORMONE therapy , *SALPINGO-oophorectomy , *BREAST self-examination , *MENOPAUSE , *BRCA genes , *FALLOPIAN tubes , *CANCER hormone therapy - Abstract
Plain language summary: This paper deals with the use of hormone replacement therapy (HRT) after the removal of fallopian tubes and ovaries to prevent ovarian cancer in premenopausal high risk women. Some women have an alteration in their genetic code, which makes them more likely to develop ovarian cancer. Two well‐known genes which can carry an alteration are the BRCA1 and BRCA2 genes. Examples of other genes associated with an increased risk of ovarian cancer include RAD51C, RAD51D, BRIP1, PALB2 and Lynch syndrome genes. Women with a strong family history of ovarian cancer and/or breast cancer, may also be at increased risk of developing ovarian cancer. Women at increased risk can choose to have an operation to remove the fallopian tubes and ovaries, which is the most effective way to prevent ovarian cancer. This is done after a woman has completed her family. However, removal of ovaries causes early menopause and leads to hot flushes, sweats, mood changes and bone thinning. It can also cause memory problems and increases the risk of heart disease. It may reduce libido or impair sexual function. Guidance on how to care for women following preventative surgery who are experiencing early menopause is needed. HRT is usually advisable for women up to 51 years of age (average age of menopause for women in the UK) who are undergoing early menopause and have not had breast cancer, to minimise the health risks linked to early menopause. For women with a womb, HRT should include estrogen coupled with progestogen to protect against thickening of the lining of the womb (called endometrial hyperplasia). For women without a womb, only estrogen is given. Research suggests that, unlike in older women, HRT for women in early menopause does not increase breast cancer risk, including in those who are BRCA1 and BRCA2 carriers and have preventative surgery. For women with a history of receptor‐negative breast cancer, the gynaecologist will liaise with an oncology doctor on a case‐by‐case basis to help to decide if HRT is safe to use. Women with a history of estrogen receptor‐positive breast cancer are not normally offered HRT. A range of other therapies can be used if a woman is unable to take HRT. These include behavioural therapy and non‐hormonal medicines. However, these are less effective than HRT. Regular exercise, healthy lifestyle and avoiding symptom triggers are also advised. Whether to undergo surgery to reduce risk or not and its timing can be a complex decision‐making process. Women need to be carefully counselled on the pros and cons of both preventative surgery and HRT use so they can make informed decisions and choices. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
- View/download PDF
33. The most 100 cited papers in addiction research on cannabis, heroin, cocaine and psychostimulants. A bibliometric cross-sectional analysis.
- Author
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Valderrama Zurián JC, Bueno Cañigral FJ, Castelló Cogollos L, and Aleixandre-Benavent R
- Subjects
- Cross-Sectional Studies, Humans, United Kingdom, United States, Bibliometrics, Biomedical Research trends, Central Nervous System Stimulants, Cocaine-Related Disorders, Heroin Dependence, Marijuana Abuse
- Abstract
The number of citations a peer-reviewed article receives is often used as a measure of its importance and scientific impact. This paper identifies, describes and categorizes the highly cited papers in addiction research on cannabis, heroin, cocaine and psychostimulants. Highly cited papers were identified in the Web of Science Core Collection database. Several bibliometric indicators were calculated. Social network analysis was applied to draw groups of authors and institutions with the greatest number of collaborations and co-words. The number of citations for the top 100 cited articles ranged from 649 to 4,672. The articles were published in 40 journals. The subject category Substance Abuse included 10 papers. The United States was the most productive country (79 papers), followed by the United Kingdom (9). The main funding institutions were the National Institutes of Health in the United States. The network of collaboration between authors distributes the 352 researchers into 53 groups. The three most cited works address the neural basis of drug craving as an incentive-sensitization theory of addiction, the clinical and research uses of the Addiction Severity Index, and the neurocircuitry of addiction. Scientific literature on addictions is widely dispersed both in multidisciplinary and specific journals of neurology, psychiatry and addictions, with relatively few publications providing most of the citations. An ongoing challenge for this field is the concentration of highly cited papers coming from a select number of countries, with the United States being the research hub of the world, with the highest volume of publications and total citations., (Copyright © 2021. Published by Elsevier B.V.)
- Published
- 2021
- Full Text
- View/download PDF
34. Bibliometric Analysis of ChatGPT's Applications in Medicine: A Comprehensive Assessment of its Impact and Potential.
- Author
-
K. K., Mueen Ahmed and M., Chaman Sab
- Subjects
CHATGPT ,BIBLIOMETRICS ,LANGUAGE models ,DATABASES ,GRAPHIC methods in statistics - Abstract
Purpose: The purpose of the paper "Bibliometric Analysis of ChatGPT's Applications in Medicine: A Comprehensive Assessment of its Impact and Potential" is to conduct a systematic evaluation of how ChatGPT, an AI language model, has been applied in the field of medicine. The study aims to assess the impact of ChatGPT's applications in medicine and explore its potential contributions to the healthcare domain. Materials and Methods: The Scopus database was selected and the search query (All (ChatGPT AND Medicine) was developed on 11, July 2023 to retrieve all the bibliographic records on the domine of interest. From each record, we retrieved data on the title, author, organizations, journals, publications type, source, country, collaboration, etc. They were exported to MS-Excel for bibliometric analysis and VOSviewer software was used for analyzing Co-Occurrence networks and the data and descriptive analysis were classified, collected one by one, and loaded into the Bibliometric R-package program to create science maps and statistical graphs. Results: ChatGPT - related Medicine papers in the Scopus database constitute 532 papers. these publications received 1046 citations, these authored by 1771 authors published 203 article type and etc. Average citations per document 1966 received and 111 (20.86%) received extremal funding support from 62+ research agencies supporting research in this area. selected 65 significant keywords appearing in ChatGPT and Medicine. USA and UK were contributed the highest papers. Medicine is the broad subject of the study were published highest number of papers (312). Conclusion: The findings from this study can help researchers, practitioners, and policymakers better understand the impact and potential of ChatGPT in advancing medical knowledge, patient care, and healthcare practices. Additionally, the paper may contribute to identifying knowledge gaps and guide further research in this rapidly evolving field at the intersection of AI and medicine. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
35. Scriptural interpretation and the formation of a popular women's movement in Britain: The Bible Readings column of the Women's Penny Paper.
- Author
-
Hetherington, Naomi
- Subjects
WOMEN'S rights ,WOMEN - Published
- 2021
36. The JCCP's response to the DHSC licensing of non-surgical cosmetic procedures first consultation paper.
- Author
-
Sines, David
- Subjects
WORK experience (Employment) ,MEDICAL quality control ,PROFESSIONS ,PROFESSIONAL licenses ,GOVERNMENT regulation ,PROFESSIONAL employee training ,PLASTIC surgery ,ESTHETICIANS (Skin care) ,CONTINUING education ,GOVERNMENT agencies ,CLINICAL competence ,MEDICAL practice ,POLITICAL participation ,PROFESSIONAL associations ,SUPERVISION of employees - Abstract
The JCCP has presented its response to the Government's first public consultation document with the aim of informing and determining the standard, type and content of the new practitioner licence [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
37. Transformational Learning: Using Equality and Diversity Marketing Client Briefs to Foster Awareness, Application and Action
- Author
-
Everett, Sally, Gunduc, Melisa, Junjunia, Maimoona, Kroener, Laura, Maise, Jakob, Scott-Hyde, Katrina, Salem, Lara, and Simsek, Asli
- Abstract
This paper reports a study coauthored with second-year undergraduate students that examines student experiences of undertaking real-life, client-set marketing assessments with an equality and inclusion remit. Students were set a marketing assessment with an explicit social justice focus, thereby prompting them to reflect on their own backgrounds and unconscious biases whilst addressing issues of societal injustice. This study explores the impact on students of closely engaging with this material and how the assessment, which involved them interviewing experts and developing actionable recommendations, altered their views and career plans. Data were generated via focus groups with students who undertook the assessment, supplemented by some alumni and client interviews. The findings are presented as a "3A" framework of Awareness, Application, and Action: first, the assessment raised "Awareness" of broader societal issues and fostered transformation in terms of personal views; second, students developed core skills and networks they could "Apply" in their future careers; and third, "Action" describes the way students felt empowered to make a positive difference to their client and wider society. The 3A model provides simple design principles that educators could implement if they want to introduce transformational experiences based on social justice issues into the marketing curriculum.
- Published
- 2023
- Full Text
- View/download PDF
38. Infrastructure and operating processes of PIONEER, the HDR-UK Data Hub in Acute Care and the workings of the Data Trust Committee: a protocol paper.
- Author
-
Gallier S, Price G, Pandya H, McCarmack G, James C, Ruane B, Forty L, Crosby BL, Atkin C, Evans R, Dunn KW, Marston E, Crawford C, Levermore M, Modhwadia S, Attwood J, Perks S, Doal R, Gkoutos G, Dormer R, Rosser A, Fanning H, and Sapey E
- Subjects
- Humans, Research Design, United Kingdom, Critical Care methods, Databases, Factual standards, State Medicine organization & administration, State Medicine statistics & numerical data
- Abstract
Introduction: Health Data Research UK designated seven UK-based Hubs to facilitate health data use for research. PIONEER is the Hub in Acute Care. PIONEER delivered workshops where patients/public citizens agreed key principles to guide access to unconsented, anonymised, routinely collected health data. These were used to inform the protocol., Methods: This paper describes the PIONEER infrastructure and data access processes. PIONEER is a research database and analytical environment that links routinely collected health data across community, ambulance and hospital healthcare providers. PIONEER aims ultimately to improve patient health and care, by making health data discoverable and accessible for research by National Health Service, academic and commercial organisations. The PIONEER protocol incorporates principles identified in the public/patient workshops. This includes all data access requests being reviewed by the Data Trust Committee, a group of public citizens who advise on whether requests should be supported prior to licensed access., Ethics and Dissemination: East Midlands-Derby REC (20/EM/0158): Confidentiality Advisory Group (20/CAG/0084). www.PIONEERdatahub.co.uk., Competing Interests: Competing interests: SG, GP, HP, GMC, CJ, BR, LF, BLC, CA, KWD, EM, CC, ML, SM, SP, JA, RDoal, RDormer, AR and HF have no conflicts of interest. GG reports funding from HDR-UK. ES reports funding from the Wellcome Trust, MRC, HDR-UK, Alpha 1 Foundation (A1F), British Lung Foundation and NIHR., (© Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY. Published by BMJ.)
- Published
- 2021
- Full Text
- View/download PDF
39. British Association of Critical Care Nurses: Evidence‐based consensus paper for oral care within adult critical care units.
- Author
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Collins, Tim, Plowright, Catherine, Gibson, Vanessa, Stayt, Louise, Clarke, Sarah, Caisley, Jo, Watkins, Claire Harcourt, Hodges, Emily, Leaver, Gillian, Leyland, Sarah, McCready, Patricia, Millin, Sara, Platten, Julie, Scallon, Michelle, Tipene, Patsy, and Wilcox, Gabby
- Subjects
- *
PNEUMONIA , *CONSENSUS (Social sciences) , *ORAL hygiene , *CRITICALLY ill , *TOOTH care & hygiene , *PATIENTS , *NOSOCOMIAL infections , *VENTILATOR-associated pneumonia , *EVIDENCE-based nursing - Abstract
Background: Patients who are critically ill are at increased risk of hospital acquired pneumonia and ventilator associated pneumonia. Effective evidence based oral care may reduce the incidence of such iatrogenic infection. Aim: To provide an evidence‐based British Association of Critical Care Nurses endorsed consensus paper for best practice relating to implementing oral care, with the intention of promoting patient comfort and reducing hospital acquired pneumonia and ventilator associated pneumonia in critically ill patients. Design: A nominal group technique was adopted. A consensus committee of adult critical care nursing experts from the United Kingdom met in 2018 to evaluate and review the literature relating to oral care, its application in reducing pneumonia in critically ill adults and to make recommendations for practice. An elected national board member for the British Association of Critical Care Nurses chaired the round table discussion. Methods: The committee focused on 5 aspects of oral care practice relating to critically ill adult patients. The evidence was evaluated for each practice within the context of reducing pneumonia in the mechanically ventilated patient or pneumonia in the non‐ventilated patient. The five practices included the frequency for oral care; tools for oral care; oral care technique; solutions used and oral care in the non‐ventilated patient who is critically ill and is at risk of aspiration. The group searched the best available evidence and evaluated this using the Grading of Recommendations Assessment, Development, and Evaluation system to assess the quality of evidence from high to very low, and to formulate recommendations as strong, moderate, weak, or best practice consensus statement when applicable. Results: The consensus group generated recommendations, delineating an approach to best practice for oral care in critically ill adult patients. Recommendations included guidance for frequency and procedure for oral assessment, toothbrushing, and moisturising the mouth. Evidence on the use of chlorhexidine is not consistent and caution is advised with its routine use. Conclusion: Oral care is an important part of the care of critically ill patients, both ventilated and non‐ventilated. An effective oral care programme reduces the incidence of pneumonia and promotes patient comfort. Relevance to Clinical practice: Effective oral care is integral to safe patient care in critical care. [ABSTRACT FROM AUTHOR]
- Published
- 2021
- Full Text
- View/download PDF
40. An innovative multi-agency consultation model for harmful sexual behaviour displayed by children and young people: practice paper.
- Author
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Ibrahim, Jeyda
- Subjects
- *
RISK-taking behavior , *COUNSELING , *HUMAN sexuality , *MATHEMATICAL models , *MENTAL health , *THEORY , *MEDICAL referrals , *HEALTH care teams , *INTERPROFESSIONAL relations , *SUPPORT groups , *SOCIAL case work - Abstract
Harmful Sexual Behaviour (HSB) has been regularly documented as a demanding area of practice within the United Kingdom (UK). The aim of this paper is to share a practice model developed in an under-resourced inner London borough. The HSB forum is formed of a multi-agency group of professionals and runs monthly providing a platform for practitioners to seek consultation for young people they are working with who are displaying HSB's. Initial feedback for the forum from practitioners has been consistently positive and they have valued specifically the opportunity to formulate, have clear directions, and the multi-disciplinary perspective. In addition, most reported feeling empowered to implement the recommendations suggested. Given the shared vulnerability factors between those displaying HSB's and other at-risk young people such as those who are being sexually exploited, this model provides an innovative way that practitioners can be supported by multiple agencies where there is a lack of specialist services. [ABSTRACT FROM AUTHOR]
- Published
- 2021
- Full Text
- View/download PDF
41. Modern slavery statements and the UK's largest housebuilding companies: an exploratory research paper.
- Author
-
Jones, Peter and Comfort, Daphne
- Subjects
CORPORATE websites ,SLAVERY ,MODERN literature ,POINT set theory ,SUBCONTRACTING - Abstract
Purpose: Modern slavery has been identified as a problem in the construction industry, but the issue has received very limited attention in the academic literature. This exploratory paper looks to explore one of the ways in which the United Kingdom (UK)'s largest housebuilding companies have publicly addressed the issue by reviewing their modern slavery statements. Design/methodology/approach: The paper adopts a simple methodological approach to review the modern slavery statements of the largest housebuilding companies within the UK and offers some reflections on these statements. Findings: The findings identified a number of policy and practice responses, which characterised the selected housebuilding companies' approaches to modern slavery. The companies' approaches to modern slavery statements were seen as aspirational and perhaps best described as a work in progress. Research limitations/implications: The authors recognise that the paper has a number of limitations. The empirical material for the review is drawn exclusively from the corporate websites of the selected housebuilding companies at a set point in time and does not include any primary information supplied by, or obtained from, the companies' executives, managers or employees or any information obtained from the companies' contractors, subcontractors or suppliers. Originality/value: The paper offers an exploratory review of the modern slavery statements published by the largest housebuilding companies within the UK. As such, the review makes a small contribution to addressing a gap in the academic literature on modern slavery within the housebuilding industry and will hopefully stimulate future research in the field. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
- View/download PDF
42. What do we mean when we say 'sport'?
- Author
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McDowell, Matthew L.
- Subjects
HISTORY of sports ,SPORTS ,CONFERENCE papers ,PHYSICAL education ,ANNUAL meetings - Abstract
This article examines the evolving historiography of 'sport' vis-à-vis the British Society of Sports History (BSSH), as per fluid and shifting definitions of what the term 'sport' means. It begins by discussing broad themes within the previous historiography of UK sport. Afterwards, it roughly quantifies the content of articles the BSSH's journal The Sports Historian/Sport in History during the period 1993–2021, with an emphasis on sporting forms and emerging trends. Finally, the author provides a similar discussion of the topics of conference papers at annual meetings of the BSSH during the period 2011–21. Throughout this article, the author, Chair of the Society from 2017 to 2019, attempts to provide some causal explanations for why certain sporting forms are popular points of discussion, how others are pushing the envelope of the term 'sport', and issues therein. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
- View/download PDF
43. Coastal impacts of storm surges on a changing climate: a global bibliometric analysis.
- Author
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Leal, Karine Bastos, Robaina, Luís Eduardo de Souza, and De Lima, André de Souza
- Subjects
STORM surges ,SEA level ,CLIMATE change ,ABSOLUTE sea level change ,CYCLONES ,BIBLIOMETRICS - Abstract
An increase in the global mean sea level is predicted during the twenty-first century, as a consequence of global average rising temperature projections. In addition, changes in the strength of atmospheric cyclonic storms may alter the development of storm surges, exacerbating the risks to coastal communities. Based on the fact that the interest and range of papers on this topic are growing, this study aims to present the status of the global scientific production on studies that have correlated climate change and the impact of storm surges on the coastal zone leading to erosion and flooding (inundation) via a bibliometric analysis. We analyzed 429 papers published in journals between January 1991 and February 2021 from the Scopus database. Through the VOSviewer and Bibliometrix R package, we describe the most relevant countries, affiliations, journals, authors, and keywords. Our results demonstrate that there has been an exponential growth in the research topic and that authors from the USA and the United Kingdom are the most prolific. Among the 1454 authors found, ten researchers published at least five papers on the topic and obtained at least 453 citations in the period. The most represented journals were the Journal of Coastal Research, Climatic Change, and Natural Hazards. We also found and discuss the lack of standardization in the choice of keywords, of which climate change, storm surge, and sea-level rise are the most frequent. Finally, we have written a guide to facilitate the authors' bibliographic review. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
- View/download PDF
44. Medical journal's refusal to retract paper used to restrict abortion in US sparks independence row.
- Author
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Davies, Madlen
- Subjects
ABORTION laws ,ABORTION in the United States ,HEALTH services accessibility ,ETHICS ,SERIAL publications ,PROFESSIONAL autonomy ,MIFEPRISTONE ,MISINFORMATION ,MEDICAL literature - Published
- 2023
- Full Text
- View/download PDF
45. British Lymphology Society's position paper for management of people with lymphoedema in presence of deep vein thrombosis: a summary.
- Author
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O'Neill, Catriona and Elwell, Rebecca
- Subjects
- *
LYMPHEDEMA treatment , *PULMONARY embolism , *VENOUS thrombosis , *MEDICAL protocols , *COMPRESSION therapy , *PROFESSIONAL associations , *PATIENT education , *DISEASE management , *POSTTHROMBOTIC syndrome , *DISEASE risk factors , *SYMPTOMS , *DISEASE complications - Abstract
There is some confusion surrounding the management of people with lymphoedema in the presence of deep vein thrombosis (DVT). This may be in relation to the suitability of commencing compression therapy or regarding the continuation of compression therapy in those who develop DVT. The purpose of this British Lymphology Society position paper is to support evidence-based practice and debunk the myths surrounding the management of DVT and lymphoedema. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
- View/download PDF
46. Community initiatives for well‐being in the United Kingdom and their role in developing social capital and addressing loneliness: A scoping review.
- Author
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Tierney, Stephanie, Rowe, Rosie, Connally, Emily L, Roberts, Nia W, Mahtani, Kamal R, and Gorenberg, Jordan
- Subjects
WELL-being ,CINAHL database ,MEDICAL information storage & retrieval systems ,SOCIAL support ,SYSTEMATIC reviews ,SOCIAL capital ,COMMUNITY support ,MENTAL health ,SOCIAL isolation ,LONELINESS ,DESCRIPTIVE statistics ,INTERPERSONAL relations ,RESEARCH funding ,SOCIAL attitudes ,LITERATURE reviews ,MEDLINE ,SOCIAL skills ,TRUST - Abstract
Introduction: Loneliness can have a negative impact on people's physical and psychological well‐being; building social capital is a potential means of addressing this connection. Community initiatives (e.g. groups, clubs, neighbourhood activities) may be a route that enables people to build social capital to tackle loneliness. Understanding what is known, and where gaps in knowledge exist, is important for advancing research on this topic. Methods: A scoping review was undertaken to explore the question – What community initiatives, with a focus on well‐being, have been evaluated in the United Kingdom that include information about social capital and loneliness? Four databases (Medline, CINAHL, ASSIA and Embase) were searched for relevant research papers. References were screened by two researchers to identify if they met the review's inclusion criteria. Data were summarised as a narrative and in tables. Results: Five papers met the review's inclusion criteria. They all used qualitative methods. Findings suggested that social capital could be developed through creating a sense of trust, group cohesion and reciprocity among participants in the community initiatives. This connection enabled people to experience a sense of belonging and to feel they had a meaningful relationship with others, which appeared to alleviate feelings of loneliness. Conclusion: More research is warranted on the review topic, including studies that have employed quantitative or mixed methods. Clarity around definitions of social capital and loneliness in future research is required. Engagement with community initiatives can provide a formalised route to help people develop connections and counteract limitations in their social networks. However, individuals may be wary about attending community initiatives, needing support and encouragement to do so. Social prescribing link workers are one means of motivating people to access groups, events or organisations that could improve their well‐being. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
47. The financial action taskforce and money laundering: critical analysis of the Panama papers and the role of the United Kingdom.
- Author
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Al-Emadi, Aisha Hassan
- Subjects
MONEY laundering ,DUE diligence - Abstract
Purpose: This paper aims to study the effectiveness of the implementation of the Financial Action Task Force (FATF) recommendations in the UK in an attempt to combat the laundering of proceeds of corruption. Design/methodology/approach: A desk review of secondary resources was conducted to analyze available literature to examine the research topic. Findings: The leakage of 11.5 million documents, known as the Panama papers, has revealed that the UK functioned as a safe haven for illicit and corrupt money. In an attempt to address this, the country called for a public registry of beneficial owners to disclose the identities of the owners of the incorporated corporations and to extend them to individuals abroad holding UK property. The FATF report recognizes the UK's far-reaching regulation. Despite the measures taken, UK still faces serious risks with regard to the laundering of criminal proceeds, which demonstrates that technical compliance with FATF rules is not enough to effectively curb money laundering. Originality/value: This study suggests that FATF rules' effectiveness in identifying instances of laundering the proceeds of corruption is limited because of the deeply rooted system vulnerabilities and the rapid changes in money laundering trends. [ABSTRACT FROM AUTHOR]
- Published
- 2021
- Full Text
- View/download PDF
48. RESEMIOTISING TEXT MEANINGS: The UK Law Commission and the summary of consultation paper on surrogacy.
- Author
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PENNISI, GIULIA ADRIANA
- Subjects
LAW reform ,COMMUNICATION laws ,COMMUNICATION in law ,INTERPERSONAL relations ,LEGISLATION drafting ,INTERPERSONAL communication ,SURROGATE mothers - Abstract
Modern legislative drafting theory urges legislative drafters in common law jurisdictions to bare the text from preliminary provisions and to start as early as possible with the regulatory message that the government is trying to convey to citizens. In line with the present legislation needs, the UK Law Commission Annual Report 2018-2019 states that "We have a statutory duty to promote the reform of the law and continue to work hard in this area", alongside the production of graphics, infographics, images and pictures "to explain in plain English each new law reform project". In this paper, O'Halloran et al.'s 2016 concept of intersemiotic translation, which takes place within and across the semiotic products or artefacts resulting from resemiotisation processes (Iedema 2003), provides the theoretical basis for the research conducted on the UK Summary of Consultation Paper "Building Families Through Surrogacy. A New Law" (2018-2019). From the analysis of the semiotic resources deployed in the Summary, it is possible to see how they function as system of meanings (i.e. experiential, logical, interpersonal and textual) and are processed at various levels (Halliday 1978, 2013; Halliday, Hasan 1985; Halliday, Matthiessen 2014). As the analysis shows, the Law Commission of England and Wales and the Scottish Law Commission develop an innovative cultural/informative communication to propose a law reform project, and deploy different semiotic resources to construct a layman's experience of the world, and the interpersonal relations, through a resemiotisation process. [ABSTRACT FROM AUTHOR]
- Published
- 2021
- Full Text
- View/download PDF
49. "It's the Best Job on the Paper" – The Courts Beat During the Journalism Crisis.
- Author
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Jones, Richard
- Subjects
JOURNALISM ,PRESS ,FREEDOM of the press ,LAW reports, digests, etc. ,TELEVISION journalists ,LAYOFFS - Abstract
Local journalism in the UK has been described as being in "crisis". Local newspapers have experienced years of declining circulations and staff cuts, leading to questions about how effectively those institutions can continue to perform normative functions of journalism. One of those is to report on the courts. Through analysis of 22 semi-structured interviews with local newspaper reporters who cover the courts beat, agency court reporters who supply the local press, as well as broadcast journalists involved in both local and national court coverage, this paper helps to establish how the daily newswork of court journalists has developed amid a turbulent period in journalism, especially local journalism. The research finds that court reporting has been less affected than other news beats but faces a series of challenges related to financial cuts and other pressures. While the local press has become even more essential to the provision of court reporting, a central part of the news media's fourth estate role, those challenges affect the ability of court reporters to perform this function. This paper recommends that policymakers consider using a form of public funding to guarantee the future of court reporting at the local level. [ABSTRACT FROM AUTHOR]
- Published
- 2021
- Full Text
- View/download PDF
50. Nurses leading male lower urinary tract symptom (LUTS) clinics: A scoping review.
- Author
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Middleton, Claire and Dunleavy, Stephanie
- Subjects
FERTILITY clinics ,CINAHL database ,RESEARCH ,UROLOGICAL nursing ,BLADDER ,NURSING ,HEALTH services accessibility ,URINARY tract infections ,SYSTEMATIC reviews ,TREATMENT effectiveness ,NURSES ,QUALITY of life ,HEALTH care teams ,DESCRIPTIVE statistics ,LITERATURE reviews ,MEDLINE ,NURSE practitioners ,SYMPTOMS - Abstract
Nurse‐led clinics are known to positively impact and benefit patients; however, there is little understanding of the role of the nurse in a nurse‐led male Lower Urinary Tract Symptoms (LUTS) clinic. LUTS affect up to 30% of males over 65 in the United Kingdom and can significantly impact the quality of life of the person experiencing them. LUTS can be managed with conservative changes, as well as with medication and surgical intervention. The aim of this scoping review is to map what is known about the role of the nurse in a nurse‐led male LUTS clinic and what research tells us regarding, the barriers and enablers in nurses leading a male LUTS clinic. This scoping review follows the Preferred Reporting Items for Systematic Reviews and Meta‐Analyses extension for Scoping Reviews (PRISMA‐SCR) checklist and the methodological guidelines set out by the Joanna Briggs institute. A literature search was carried out over three databases (CINAHL, Medline Ovid, ProQuest health and medical collection) and systematically searched from 2000 to 2021. Grey literature was also searched, and citation chaining was undertaken. Following a systematic review of the literature, four papers met the inclusion criteria for this scoping review. The emergent themes across the four papers consisted of structure, assessment and resources, and effectiveness of the nurse‐led male LUTS clinic. There was clear agreement across the literature regarding the investigations and assessment the nurse should carry out. Ongoing practical, theoretical, and observational training and education is required to ensure the nurse is competent in running a male LUTS clinic. The papers reviewed showed the nurse provided a supportive role to the consultant. However, there is evidence indicating there is a move towards autonomous practice. There is a dearth of the current research relating to the role of the nurse in nurse‐led male LUTS clinics and the enablers and barriers in nurses leading male LUTS clinics. Further research should be considered to gain a better understanding of where nurse‐led male LUTS clinics currently take place, what the role of the nurse is in leading a LUTS clinic and what enablers and barriers exist. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
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