1. Factors associated with extubation failure in an intensive care unit: a case-control study.
- Author
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Braga Arcanjo, Ana Beatriz and Marinilza Beccaria, Lúcia
- Subjects
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INTENSIVE care units , *STATISTICS , *CRITICALLY ill , *MULTIVARIATE analysis , *PATIENTS , *CASE-control method , *RETROSPECTIVE studies , *QUANTITATIVE research , *FISHER exact test , *MANN Whitney U Test , *EXTUBATION , *TREATMENT failure , *T-test (Statistics) , *CHI-squared test , *STATISTICAL hypothesis testing , *DESCRIPTIVE statistics , *VENTILATOR weaning , *DATA analysis software , *LOGISTIC regression analysis , *LONGITUDINAL method - Abstract
Objective: to investigate the factors associated with extubation failure of patients in the intensive care unit. Method: unpaired, longitudinal, retrospective and quantitative case-control with the participation of 480 patients through clinical parameters for ventilator weaning. Data were analyzed by: Fisher's exact test or the chi-square test; unpaired two-tailed Student's t test; and Mann-Whitney test. Significant P values lower than or equal to 0.05 were admitted. Results: of the patients, 415 (86.5%) were successful and 65 (13.5%) failed. Success group: the most negative fluid balance, APACHE II in 20 (14-25), weak cough in 58 (13.9%). Failure group: the most positive fluid balance, APACHE II in 23 (19-29), weak cough in 31 (47.7%), abundant amount of pulmonary secretions in 47.7%. Conclusion: positive fluid balance and the presence of inefficient cough or inability to clear the airway were predictors of extubation failure. [ABSTRACT FROM AUTHOR]
- Published
- 2023
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