38 results on '"MEN who have sex with men"'
Search Results
2. Continuing Low Awareness and Use of Pre-exposure Prophylaxis (PrEP) for HIV among People Who Inject Drugs (PWID), San Francisco, 2022.
- Author
-
Suprasert, Bow, Tate, Moranda, Reagan, Danyion, Ruiz, Raul, Gao, Katherine, McNaughton, Katherine, Miller, Kassandra, Marr, Alexander, Taylor, Kelly D., Wilson, Erin C., and McFarland, Willi
- Subjects
HIV prevention ,HEALTH literacy ,HEALTH services accessibility ,STATISTICAL models ,RESEARCH funding ,HUMAN sexuality ,INTERVIEWING ,QUESTIONNAIRES ,FISHER exact test ,MULTIPLE regression analysis ,AGE distribution ,DESCRIPTIVE statistics ,CHI-squared test ,PRE-exposure prophylaxis ,ODDS ratio ,MEN who have sex with men ,HEROIN ,HARM reduction ,SURVEYS ,SEX customs ,METROPOLITAN areas ,CONFIDENCE intervals ,MEDICAL screening ,DATA analysis software ,INTRAVENOUS drug abusers ,PSYCHOSOCIAL factors ,PEOPLE with disabilities - Abstract
Clinical trials provide evidence that pre-exposure prophylaxis (PrEP) prevents HIV acquisition including through sharing of injection equipment among people who inject drugs (PWID). However, uptake among many populations at risk for HIV has been slow, particularly among PWID. We examined data from the National HIV Behavioral Surveillance (NHBS) from San Francisco in 2022 to measure PrEP uptake and identify factors associated with PrEP awareness among PWID. Of 479 PWID with HIV-negative or unknown HIV status, 54.9% were aware of PrEP, 5.9% had discussed PrEP with a healthcare provider, and 1.5% had used PrEP in the past year. Lack of PrEP awareness was associated with being age 50 years and older (adjusted odds ratio [aOR] 0.40, 95% CI 0.27–0.60), being men who have sex with women (vs. men who have sex with men, aOR 0.47, 95% CI 0.24–0.92), having a disability (aOR 0.58, 95% CI 0.35–0.95), using heroin as their most frequently injected drug (aOR 0.51, 95% CI, 0.34–0.78), not having tested for HIV, HCV, or an STD in the past year (aOR 0.43, 95% CI 0.28–0.64), and not having access to new sterile needles in the past year (aOR 0.28, 95%CI 0.08–1.00). We found negligible change in the awareness and uptake of PrEP among PWID since previously measured in NHBS in 2018. Low PrEP use among PWID may be addressed by increasing provider discussion of PrEP with their PWID patients and clients during routine care, expanding testing for injection-related infections among PWID, and integrating PrEP access into harm reduction programs. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
3. Strategies to Close the PrEP Uptake Gap Among Transgender People and Men Who Have Sex with Men in Tshwane, South Africa: Perspectives from the Community.
- Author
-
Perez-Urbano, India, Dilraj, Athmanundh, Pitsi, Annah, Hlongwane, Naomi, Abdelatif, Nada, Dietrich, Janan, and Ahmed, Khatija
- Subjects
HIV prevention ,CROSS-sectional method ,COMMUNITY health services ,RESEARCH funding ,INTERVIEWING ,LOGISTIC regression analysis ,DESCRIPTIVE statistics ,PRE-exposure prophylaxis ,MEN who have sex with men ,THEMATIC analysis ,CISGENDER people ,RESEARCH methodology ,PUBLIC health ,TRANS women ,HEALTH promotion - Abstract
HIV Pre-exposure Prophylaxis (PrEP) uptake among transgender (TG) people and gay men and other men who have sex with men (MSM) remains low, despite South Africa being the first African country to approve PrEP. This mixed-methods study used a two-phase explanatory sequential design: (1) quantitative analysis of cross-sectional surveys followed by (2) qualitative in-depth interviews. This study explored facilitators and barriers to PrEP uptake to identify strategies to increase utilization in these key populations. We conducted 202 cross-sectional surveys and 20 in-depth interviews between July 2021 and March 2022 in Soshanguve, Tshwane, Gauteng. Quantitative data were analyzed using univariate logistic regression; thematic analysis was performed for qualitative data. Findings show high willingness to use PrEP but low PrEP uptake. We outline strategies to facilitate PrEP use: (1) demystify daily PrEP by deploying community-engaged PrEP education campaigns; (2) capitalize on existing peer networks; and (3) expand accessible and culturally responsive PrEP service delivery models. We provide feasible recommendations to close the PrEP uptake gap in these key populations in South Africa. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
4. Low Self-Perceived Need for PrEP and Behavioral Indications of MSM Who Recently Refused Daily PrEP: A Mixed Methods Study in Three U.S. Cities.
- Author
-
Kota, Krishna Kiran, Gelaude, Deborah, Carnes, Neal, Schoua-Glusberg, Alisú, Frew, Paula M., Randall, Laura, Gale, Bryan, Betley, Valerie, and Mansergh, Gordon
- Subjects
HIV prevention ,HEALTH literacy ,SEXUAL partners ,THERAPEUTICS ,HEALTH attitudes ,RISK-taking behavior ,RESEARCH funding ,INTERVIEWING ,HUMAN sexuality ,CONFIDENCE ,DESCRIPTIVE statistics ,MEN who have sex with men ,PRE-exposure prophylaxis ,ATTITUDE (Psychology) ,THEMATIC analysis ,SEX customs ,CONDOMS ,AIDS serodiagnosis ,PATIENT refusal of treatment ,COMPARATIVE studies ,SEXUAL minorities ,PATIENTS' attitudes ,PREVENTIVE health services ,SELF-perception - Abstract
Copyright of AIDS & Behavior is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2024
- Full Text
- View/download PDF
5. Variations in HIV Prevention Coverage in Subpopulations of Australian Gay and Bisexual Men, 2017–2021: Implications for Reducing Inequities in the Combination Prevention Era.
- Author
-
Holt, Martin, Chan, Curtis, Broady, Timothy R., MacGibbon, James, Mao, Limin, Smith, Anthony K. J., Rule, John, and Bavinton, Benjamin R.
- Subjects
HIV infection epidemiology ,HIV prevention ,CROSS-sectional method ,SEXUAL partners ,HEALTH services accessibility ,RISK assessment ,VIRAL load ,RESEARCH funding ,GAY men ,BISEXUALITY ,HUMAN sexuality ,EVALUATION of human services programs ,QUESTIONNAIRES ,PRE-exposure prophylaxis ,PSYCHOLOGY of HIV-positive persons ,SEX customs ,MEN who have sex with men ,CONDOMS ,HOMOSEXUALITY ,SAFE sex ,BISEXUAL people ,SEXUAL minorities ,PSYCHOSOCIAL factors - Abstract
Copyright of AIDS & Behavior is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2024
- Full Text
- View/download PDF
6. PrEP to Party: Exploring MSM's PrEP Use and Interest in the Context of Sexually Themed Events.
- Author
-
Weinstein, Elliott R., Puccinelli, Marc, Cardenas, Nicolas, Safren, Steven A., and Harkness, Audrey
- Subjects
HIV prevention ,ATTITUDES toward AIDS (Disease) ,RESEARCH funding ,HUMAN sexuality ,LOGISTIC regression analysis ,DESCRIPTIVE statistics ,MEN who have sex with men ,PRE-exposure prophylaxis ,SPECIAL days ,SEX customs ,RESEARCH methodology ,DATA analysis software - Abstract
Sexually themed events present a unique opportunity for scaling up pre-exposure prophylaxis (PrEP) to men who have sex with men (MSM). This study descriptively explored PrEP uptake among MSM who anticipated attending a week-long major South Florida sexually themed event and examined potential facilitators and barriers to PrEP engagement among potential attendees. Of the participating HIV-negative MSM (n = 96), 66.7% were currently taking PrEP. Prior attendance at sexually themed events was significantly associated with current PrEP engagement and almost 75% of HIV-negative MSM not on PrEP reported high interest in taking PrEP if offered for free at future events. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
7. Pilot Randomized Controlled Trial of Game Plan for PrEP: A Brief, Web and Text Message Intervention to Help Sexual Minority Men Adhere to PrEP and Reduce Their Alcohol Use.
- Author
-
Wray, Tyler B., Chan, Philip A., Kahler, Christopher W., Ocean, Erik M. S., and Nittas, Vasileios
- Subjects
PREVENTION of alcoholism ,HIV prevention ,PATIENT compliance ,SELF-evaluation ,MOBILE apps ,RESEARCH funding ,MEDICAL care ,GAY men ,STATISTICAL sampling ,PILOT projects ,DIGITAL health ,BRIEF psychotherapy ,INTERNET ,UNSAFE sex ,RANDOMIZED controlled trials ,TREATMENT effectiveness ,PRE-exposure prophylaxis ,TELEMEDICINE ,MEN who have sex with men ,MEN'S health ,DRUGS ,TEXT messages ,SEXUAL minorities ,BIOMARKERS - Abstract
Suboptimal adherence to oral PrEP medications, particularly among younger sexual minority men (SMM), continues to be a key barrier to achieving more substantial declines in new HIV infections. Although variety of interventions, including web and text-message-based applications, have successfully addressed PrEP adherence, very few have addressed the potential influence of alcohol. This pilot study explored whether the Game Plan for PrEP, a brief, web-based and text messaging intervention, helped promote PrEP persistence and adherence and reduced condomless sex and alcohol use. Seventy-three heavy-drinking SMM on PrEP were recruited online from states with Ending the HIV Epidemic jurisdictions and randomly assigned 1:1 to receive either the Game Plan for PrEP intervention or an attention-matched control. We collected online surveys assessing primary outcomes at one, three, and six months post-enrollment. As secondary outcomes, we also collected dried blood spot samples at baseline, three, and six months to analyze for biomarkers of PrEP and alcohol use. Our results showed that the odds of stopping PrEP or experiencing a clinically meaningful lapse in PrEP adherence (≥ 4 consecutive missed doses) were not different across the two conditions. We also did not find evidence of any differences in condomless sex or drinking outcomes across conditions, although participants in both conditions reported drinking less often over time. These findings were consistent across both self-reported outcomes and biomarkers. Overall, we did not find evidence that our brief, web and text messaging intervention encouraged more optimal PrEP coverage or moderate their alcohol use. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
8. Dynamicity of HIV Pre-exposure Prophylaxis Usage Pattern and Association with Executed Adherence in MSM: An Implementation Study in Hong Kong.
- Author
-
Wong, Ngai Sze, Chan, Denise Pui-Chung, Kwan, Tsz Ho, Lui, Grace Chung-Yan, Lee, Krystal Chi-Kei, and Lee, Shui Shan
- Subjects
CLINICAL drug trials ,HIV prevention ,PATIENT compliance ,RESEARCH funding ,HUMAN sexuality ,LOGISTIC regression analysis ,DESCRIPTIVE statistics ,MULTIVARIATE analysis ,MEN who have sex with men ,PRE-exposure prophylaxis ,ODDS ratio ,STATISTICS ,DATA analysis software ,CONFIDENCE intervals ,PREVENTIVE health services - Abstract
Pre-exposure prophylaxis (PrEP) use has been shown to be effective for HIV prevention in men who have sex with men (MSM). PrEP use coverage aside, maintenance of high PrEP adherence is crucial in ensuring the achievement of HIV prevention. In this PrEP implementation study in Hong Kong, we examined the patterns of PrEP use in MSM and evaluated their association with prevention-effective adherence for HIV prevention. In January 2020–June 2021 in Hong Kong, 312 recruited MSM (median 30 years old) were followed up for 1 year, with HIV and creatinine testing, consultation, and PrEP refill. No HIV breakthrough infection was observed. As a measure of prevention-effective adherence, executed adherence (EA) was expressed as the proportion of days with HIV risk that were protected by PrEP and/or condom in 6 months. In 65,585 diary entries of 215 MSM, the median proportion of EA achieved was 89% (IQR 84–93%). Three latent classes of PrEP users were identified by latent class analysis. Taking Class 1 "daily dominant PrEP" (n = 113, 53%) as reference, Class 2 "episodic PrEP" (n = 76, 35%) was adopted by MSM with less sexual activity, had less PrEP refill and lower EA level, while Class 3 "mixed PrEP schedule" (n = 26, 12%) MSM were more sexually active but with a similar EA level. The study findings showed varied and dynamic PrEP usage patterns in the real-world setting. Strategies for promoting adherence are needed to ensure the maintenance of high EA level among PrEP-using MSM especially those on episodic PrEP schedule. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
9. Condomless Anal Sex Between Male Sex Workers and Clients in the Age of Hookup Apps.
- Author
-
Siegel, Karolynn, Cabán, María, Brown-Bradley, Courtney J., and Schrimshaw, Eric W.
- Subjects
HIV infection epidemiology ,PREVENTION of sexually transmitted diseases ,HIV prevention ,EPIDEMIOLOGY of sexually transmitted diseases ,HEAT ,SUBSTANCE abuse ,HUMAN sexuality ,MOBILE apps ,SEX work ,INTERVIEWING ,RISK assessment ,PRE-exposure prophylaxis ,QUALITATIVE research ,INCOME ,HOMOSEXUALITY ,SEX customs ,SEXUAL minorities ,ALCOHOL drinking ,RESEARCH funding ,ANAL sex ,MEN who have sex with men ,SEXUAL partners ,DATING (Social customs) ,UNSAFE sex ,CUSTOMER satisfaction - Abstract
Copyright of AIDS & Behavior is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2024
- Full Text
- View/download PDF
10. Latent Class Analysis of Online Platforms for Partner-Seeking and Sexual Behaviors Among Men Who Have Sex with Men from Central Kentucky.
- Author
-
Pravosud, Vira, Ballard, April M, Holloway, Ian W, and Young, April M
- Subjects
HIV prevention ,CONFIDENCE intervals ,HUMAN sexuality ,MOBILE apps ,PRE-exposure prophylaxis ,RISK assessment ,SEX customs ,RESEARCH funding ,SEXUAL partners ,MEN who have sex with men ,LOGISTIC regression analysis ,ANAL sex ,CONDOMS ,LATENT structure analysis - Abstract
Copyright of AIDS & Behavior is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2024
- Full Text
- View/download PDF
11. Interpersonal and Community-Level Influences Across the PrEP Cascade Among Young Adult Latinx Men who Have Sex with Men Living in a US-Mexico Border Region: A Qualitative Study.
- Author
-
Wells, Kristen J., Gordon, Janna R., Carrizosa, Claudia M., Mozo, Eduardo Hernandez, Lucido, Nicholas C., Cobian Aguilar, Rosa A., Brady, John P., Rojas, Sarah A., Ramers, Christian B., Nogg, Kelsey A., Fahey, Kalina M. L., Jones, Isaiah J., Rivera, David B., and Blashill, Aaron J.
- Subjects
HIV prevention ,HEALTH services accessibility ,HUMAN research subjects ,HISPANIC Americans ,CROSS-sectional method ,SELF-evaluation ,RESEARCH methodology ,INTERVIEWING ,SOCIAL stigma ,PRE-exposure prophylaxis ,QUALITATIVE research ,INFORMED consent (Medical law) ,SURVEYS ,DRUGS ,INTERPERSONAL relations ,SEXUAL minorities ,INTERSECTIONALITY ,DESCRIPTIVE statistics ,RESEARCH funding ,MEN who have sex with men ,PATIENT compliance ,JUDGMENT sampling ,CONTENT analysis ,DATA analysis software ,ADULTS - Abstract
Latinx men who have sex with men (MSM) are an at-risk population for new HIV diagnoses. Pre-exposure prophylaxis (PrEP) is a suite of biomedical approaches to prevent HIV infection. Latinx MSM are less likely to take PrEP compared to non-Latinx White MSM. This qualitative study identified interpersonal- and community-level barriers and facilitators of PrEP among young adult Latinx MSM. Using stratified purposeful sampling, 27 Latinx men, ages 19–29 years and living in a US-Mexico border region, completed self-report demographic surveys and participated in semi-structured in-depth interviews assessing barriers and facilitators to PrEP. Directed content analysis was used to identify both a priori and emerging themes. Most participants reported that other people, including peers, friends, partners, and health care providers were both supportive and discouraging of PrEP use. Participants' intersectional identities as members of both Latinx and LGBTQ+ (Lesbian, Gay, Bisexual, Transgender, Queer) communities both hindered and facilitated PrEP use. Resumen: Los hombres latinx que tienen sexo con hombres (latinx HSH) son una población en riesgo para nuevos diagnósticos de VIH. La profilaxis preexposición (PrEP) es un conjunto de propuestas biomédicas para prevenir la infección por VIH. Los latinx HSH son menos propensos a tomar PrEP en comparación con hombres blancos no latinx, que tiene sexo con hombres. Este estudio cualitativo identificó barreras interpersonales y comunitarias, así como facilitadores de la PrEP entre jóvenes latinx HSH. Usando un muestreo intencional estratificado, 27 hombres latinx, de 19 a 29 años y que viven en una región fronteriza de EE. UU. y México, completaron encuestas demográficas de autoinforme y participaron en entrevistas en profundidad, semiestructuradas, para evaluar las barreras y los facilitadores de PrEP. Se utilizó el análisis de contenido dirigido para identificar temas a priori y emergentes. La mayoría de los participantes informaron que otras personas, incluyendo compañeros, amigos, parejas y proveedores de atención médica, tanto apoyaban como desalentaban el uso de la PrEP. Las identidades interseccionales de los participantes como miembros de comunidades latinx y LGBTQ+ (lesbianas, gays, bisexuales, transgénero, queer) obstaculizaron y facilitaron el uso de PrEP. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
12. Psychological and Behavioural Within-participant Predictors of Adherence to Oral HIV Pre-Exposure Prophylaxis (PrEP).
- Author
-
Taylor, Alison, Hayes, Rosalie, Nwokolo, Nneka, Whitlock, Gary, Dosekun, Olamide, McCormack, Sheena, Gafos, Mitzy, and Evangeli, Michael
- Subjects
CLINICAL drug trials ,HIV prevention ,ORAL drug administration ,CROSS-sectional method ,HUMAN behavior models ,FISHER exact test ,PRE-exposure prophylaxis ,T-test (Statistics) ,PSYCHOSOCIAL factors ,DESCRIPTIVE statistics ,QUESTIONNAIRES ,EMTRICITABINE-tenofovir ,SCALE analysis (Psychology) ,CHI-squared test ,RESEARCH funding ,PATIENT compliance ,MEN who have sex with men ,STATISTICAL sampling ,DATA analysis ,GAY men ,BISEXUAL people - Abstract
Oral PrEP's effectiveness relies on adequate adherence during periods of substantial HIV risk. Since most PrEP users will miss doses, understanding predictors within participants can help to explain adherence. We used a cross-sectional, within-participant design with 67 gay, bisexual, and other men who have sex with men taking PrEP daily. Using a questionnaire, informed by the Information Motivation Behavioral Skills Model, participants were asked about an adherent and a non-adherent episode. PrEP non-adherence was associated with non-normality of the day (p <.001), being out of the home (p <.001), weekend days (p =.01), having company (p =.02), using substances (p = 0.02), not using reminders (p =.03), lower PrEP information (p =.04), lower behavioural skills (p <.001) and less positive affect (p =.002). PrEP adherence assessment could focus on situational variations, supporting the construction of alternative strategies to facilitate adherence in these situations. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
13. Identifying HIV PrEP Attributes to Increase PrEP Use Among Different Groups of Gay, Bisexual, and Other Men Who Have Sex with Men: A Latent Class Analysis of a Discrete Choice Experiment.
- Author
-
Dawit, Rahel, Predmore, Zachary, Raifman, Julia, Chan, Philip A., Skinner, Alexandra, Napoleon, Siena, Zanowick-Marr, Alexandra, Le Brazidec, Danielle, Almonte, Alexi, and Dean, Lorraine T.
- Subjects
HIV prevention ,STRUCTURAL equation modeling ,TIME ,TRAVEL ,MEDICAL care costs ,CONSUMER attitudes ,PRE-exposure prophylaxis ,PSYCHOLOGY of gay people ,PSYCHOSOCIAL factors ,QUESTIONNAIRES ,DESCRIPTIVE statistics ,HEALTH insurance ,RESEARCH funding ,MEN who have sex with men ,LOGISTIC regression analysis ,BISEXUAL people - Abstract
Daily pre-exposure prophylaxis (PrEP) is highly effective at preventing HIV among gay, bisexual, and other men who have sex with men (GBMSM), although uptake remains suboptimal. By identifying the features of PrEP that appeal to various subgroups of GBMSM, this study aimed to improve PrEP uptake by examining preferences for PrEP use. Adults ≥ 18 years old in six New England states completed an online discrete choice experiment survey. A latent class analysis (LCA) was conducted to identify groups of GBMSM based on four attributes of choices for PrEP (cost, time, side effects, and mode of administration). Multinominal logistic regression was conducted to compare the association between sociodemographic and behavioral characteristics and class memberships. Data from 675 GBMSM were analyzed. A 3-Class model was selected as the best fit model. Class 1 (47.7% of individuals) was identified as having "no specific preferences". Class 2 (18.5% of individuals) were "Cost- and time-conscious" and were significantly more likely to be older, have prior sexually transmitted infection (STI) testing, have low household income, private insurance, and have extreme concerns about HIV risk than those with no specific preference (Class 1). Finally, Class 3 (34.1% of individuals) were "Side effects-conscious" and were more likely to have low income, private insurance, and have moderate and extreme concerns about HIV risk than those with no specific preference (Class 1). Findings indicate that outreach to GBMSM who have never used PrEP should emphasize low cost and short travel times to increase potential PrEP use. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
14. Collaborative PrEP Implementation Strategies for Latino Men Who have Sex with Men: A Health Center-Community Consensus Process.
- Author
-
Ross, Jonathan, Betancourt, Gabriela S., Andrade, Elí A., Klein, Augustus, Marrero, Lissette, Morales, Gustavo A., Rivera, Sage, Watnick, Dana L., and Patel, Viraj V.
- Subjects
- *
HIV prevention , *CONSENSUS (Social sciences) , *HEALTH facilities , *BRAINSTORMING , *FOCUS groups , *HISPANIC Americans , *SOCIAL media , *COMMUNITY health services , *PRE-exposure prophylaxis , *HUMAN services programs , *INTERPROFESSIONAL relations , *RESEARCH funding , *COMMUNICATION , *MEN who have sex with men , *COLLECTION & preservation of biological specimens , *DELPHI method , *TELEMEDICINE - Abstract
Community-based organizations (CBOs) deliver services in culturally-responsive ways, and could effectively partner with health centers to deliver HIV pre-exposure prophylaxis (PrEP) to Latino men who have sex with men (LMSM). However, few such models exist. We conducted a planning study in collaboration with three CBOs serving LMSM to identify optimal PrEP delivery strategies for health centers and CBOs to implement jointly. We established a Community Expert Panel (CEP) of eight client-facing CBO and health center staff. Over 6 months, the panel met monthly to identify collaborative strategies for PrEP delivery, using a modified Delphi method consisting of the following steps: (1) brainstorming strategies; (2) rating strategies on acceptability, appropriateness and feasibility; (3) review of data from qualitative focus group discussions with CBO clients; and (4) final strategy selection. The panel initially identified 25 potential strategies spread across three categories: improving communication between health centers and CBOs; using low-barrier PrEP options (e.g. telemedicine), and developing locally-relevant, culturally-sensitive outreach materials. Focus groups with CBO clients highlighted a desire for flexible options for PrEP-related care and emphasized trust in CBOs. The final package of strategies consisted of: (1) a web-based referral tool; (2) telemedicine appointments; (3) geographically-convenient options for lab specimen collection; (4) tailored print and social media; and (5) regular coaching sessions with CBO staff. Through a community-engaged process, we identified a package of PrEP delivery strategies that CBOs and health centers can implement in partnership, which have the potential to overcome barriers to PrEP for LMSM. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
15. Cannabis Use Frequency is Associated with PrEP Cessation and Self-reported HIV Diagnosis.
- Author
-
Morgan, Ethan, Eaton, Lisa A., and Watson, Ryan J.
- Subjects
CLINICAL drug trials ,HIV prevention ,HIV infection risk factors ,SUBSTANCE abuse ,CANNABIS (Genus) ,MEN'S health ,CONFIDENCE intervals ,HISPANIC Americans ,SELF-evaluation ,GENDER-nonconforming people ,PRE-exposure prophylaxis ,RISK assessment ,SEXUAL minorities ,RESEARCH funding ,DESCRIPTIVE statistics ,PATIENT compliance ,MEN who have sex with men ,TRANS men ,ODDS ratio ,AFRICAN Americans ,SECONDARY analysis ,GAY men ,DISEASE complications - Abstract
To achieve stated targets in the United States of Ending the HIV Epidemic by 2030, it is necessary to decrease rates of pre-exposure prophylaxis use (PrEP) cessation. In particular, it is key to assess PrEP use and cannabis use frequency given the recent wave of cannabis decriminalization across the U.S., particularly among sexual minority men and gender diverse (SMMGD) individuals. We used data from the baseline visit of a national study of Black and Hispanic/Latino SMMGD. Among participants reporting any lifetime cannabis use, we further assessed the association between frequency of cannabis use in the past 3 months and: (1) self-reported PrEP use, (2) recency of last PrEP dose, and (3) HIV status using adjusted regression models. Compared to those who never used cannabis, odds of PrEP cessation were higher among those who used it once or twice (aOR 3.27; 95% CI 1.38, 7.78), those who used it monthly (aOR 3.41; 95% CI 1.06, 11.01), and those who used it weekly or more frequently (aOR 2.34; 95% CI 1.06, 5.16). Similarly, those reporting cannabis use 1–2 times in the past 3 months (aOR 0.11; 95% CI 0.02, 0.58) and those reporting weekly or more frequent use (aOR 0.14; 95% CI 0.03, 0.68) were each more likely to report more recent PrEP cessation. These results suggest that cannabis users in general may be a population at elevated risk of HIV diagnosis although more research regarding these findings is needed with nationally representative populations. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
16. The Use of Daily and On-Demand Oral Pre-Exposure Prophylaxis Dosing Strategies Among Young Adult Gay, Bisexual and Other Men who have Sex with Men Enrolled in an mHealth Adherence Intervention.
- Author
-
Horvath, Keith J., Ma, Junye, Storholm, Erik D., Black, Ashley, Klaphake, Jonathan, and Baker, Jason V.
- Subjects
HIV prevention ,PILOT projects ,THERAPEUTICS ,ORAL drug administration ,SELF-evaluation ,ATTITUDE (Psychology) ,HUMAN sexuality ,ANTIRETROVIRAL agents ,RACE ,MENTAL health ,PRE-exposure prophylaxis ,DRUGS ,RESEARCH funding ,DESCRIPTIVE statistics ,PACIFIC Islanders ,MEN who have sex with men ,PATIENT compliance ,GAY people ,TELEMEDICINE ,ADULTS - Abstract
Pre-exposure prophylaxis (PrEP) is a highly effective HIV prevention option for gay, bisexual and other men who have sex with men (GBMSM). However, with newer PrEP options, a greater understanding of whether and why GBMSM switch dosing strategies is needed to inform clinical practice and research. We assessed the dosing strategies (daily or on-demand) of GBMSM enrolled in an mHealth PrEP adherence pilot intervention at four timepoints over approximately 10 months. Among GBMSM with complete data (n = 66), a consistent daily dosing strategy was used by most (73%) participants across all time points, while on-demand PrEP was used at least once during the study period by 27% of participants. A higher percentage of on-demand PrEP users self-reported as Asian/Pacific Islander and had less positive attitudes toward PrEP, adjusting for key sociodemographic variables and intervention arm. Daily PrEP users reported high numbers of sexual partners, and the primary reason that they would switch to on-demand PrEP is reduced sexual activity. At the final assessment, 75% of participants were taking daily PrEP, of whom 27% reported that they would like to switch to another option, including on-demand and long-acting injectable PrEP. While findings were largely descriptive, they showed that switches in PrEP dosing strategies are relatively common and PrEP strategy choice may vary across racial and ethnic groups. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
17. Attitudes Towards Treatment as Prevention Among PrEP-Experienced Gay and Bisexual Men in Australia.
- Author
-
Dowell-Day, Alexander, Dobbins, Timothy, Chan, Curtis, Fraser, Doug, Holt, Martin, Vaccher, Stefanie J., Clifton, Brent, Zablotska, Iryna, Grulich, Andrew, and Bavinton, Benjamin R.
- Subjects
HIV prevention ,THERAPEUTICS ,SCIENTIFIC observation ,ATTITUDE (Psychology) ,CROSS-sectional method ,MULTIPLE regression analysis ,VIRAL load ,PRE-exposure prophylaxis ,PSYCHOSOCIAL factors ,SEXUAL minorities ,DESCRIPTIVE statistics ,RESEARCH funding ,MEN who have sex with men ,ANAL sex ,GAY men ,BISEXUAL people ,LONGITUDINAL method - Abstract
The introduction of HIV pre-exposure prophylaxis (PrEP) has the potential to impact the attitudes gay and bisexual men (GBM) who consequently choose to take PrEP have towards treatment as prevention (TasP), and the extent to which they are willing to have condomless anal intercourse (CLAI) with an HIV-positive sexual partner who has an undetectable viral load (UVL). Using a cross-sectional sample from an observational cohort study conducted from August 2018 to March 2020, we examined the extent to which PrEP-experienced GBM are willing to have CLAI with a partner who has a UVL. Simple and multiple logistic regression models were used to identify associated variables. Of the 1386 participants included in the analyses, 79.0% believed in the effectiveness of TasP, and 55.3% were willing to have CLAI with a partner who has a UVL. Wiling participants were less worried about getting HIV when taking PrEP and more likely to believe in TasP. Further research is needed to better understand the gap between belief in TasP and willingness to have CLAI with a partner who has a UVL among PrEP-experienced GBM. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
18. Optimizing Uptake of Long-Acting Injectable Pre-exposure Prophylaxis for HIV Prevention for Men Who Have Sex with Men.
- Author
-
Dean, Lorraine T., Predmore, Zachary, Skinner, Alexandra, Napoleon, Siena, Chan, Philip A., and Raifman, Julia
- Subjects
HIV prevention ,HEALTH services accessibility ,INJECTIONS ,MULTIPLE regression analysis ,MEDICAL care costs ,PRE-exposure prophylaxis ,CONTROLLED release preparations ,RESEARCH funding ,DECISION making ,DESCRIPTIVE statistics ,MEN who have sex with men ,DRUG side effects ,GAY men - Abstract
Copyright of AIDS & Behavior is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2023
- Full Text
- View/download PDF
19. Substance Use and Adherence to HIV Pre-Exposure Prophylaxis in Studies Enrolling Men Who Have Sex with Men and Transgender Women: A Systematic Review.
- Author
-
Gebru, Nioud Mulugeta, Canidate, Shantrel S., Liu, Yiyang, Schaefer, Sage E., Pavila, Emmely, Cook, Robert L., and Leeman, Robert F.
- Subjects
HIV infection epidemiology ,DRUG therapy ,DIPHOSPHONATES ,HIV prevention ,HIV infections ,ANTI-HIV agents ,ONLINE information services ,SUBSTANCE abuse ,MEDICAL information storage & retrieval systems ,TRANS women ,SYSTEMATIC reviews ,SELF-evaluation ,TENOFOVIR ,PRE-exposure prophylaxis ,TREATMENT effectiveness ,HOMOSEXUALITY ,DRUGS ,RESEARCH funding ,SEXUAL minorities ,PATIENT compliance ,MEN who have sex with men ,MEDLINE ,LONGITUDINAL method - Abstract
Optimal adherence to pre-exposure prophylaxis (PrEP) is critical, but challenging. Men who have sex with men and transgender women have high rates of HIV incidence and substance use. Substance use is associated with reduced adherence to other medications, but associations between substance use and adherence to PrEP are less clear. Thus, the current review 1) systematically evaluates the measurement of substance use and PrEP adherence in studies examining both and 2) summarizes reported findings. Peer-reviewed articles published between 2010 - April 2021 examining associations between substance use and PrEP adherence were reviewed. Fifty studies met inclusion criteria. Assessment of substance use (i.e., mostly via self-reports at baseline) and PrEP adherence (i.e., often via tenofovir diphosphate [TFV-DP] concentration levels at follow-up) varied considerably across studies. Many studies used categorical variables (e.g., substance use: yes/no). Studies using TFV-DP levels defined adherence consistently (i.e., TFV-DP ≥ 700 fmol/punch), with slight variations. Qualitative studies (n = 10) indicated that substance use (mainly alcohol) is related to poorer PrEP adherence. While quantitative findings to date are equivocal for alcohol, there is a pattern of findings linking stimulant use with poorer PrEP adherence. This review reveals four methodological gaps, which can be addressed in future research by: 1) use of uniform benchmarks for substance use measures, 2) prospective assessment for substance use, 3) use of continuous outcome variables wherever possible, and 4) more extensive consideration of potential confounders. Addressing these methodological gaps may help us reach more definitive conclusions regarding associations between substance use and PrEP adherence. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
20. High Interest in Long-acting Injectable Pre-exposure Prophylaxis (LAI-PrEP) for HIV Prevention Among Men Who Have Sex With Men (MSM): Result From A Nationwide Survey in Malaysia.
- Author
-
Paudel, Kiran, Gupta, Sana, Gautam, Kamal, Wickersham, Jeffrey A, Khati, Antoine, Azwa, Iskandar, Ha, Toan, and Shrestha, Roman
- Subjects
- *
HIV prevention , *HIV infections , *INJECTIONS , *HEALTH services accessibility , *CONFIDENCE intervals , *MIDDLE-income countries , *CROSS-sectional method , *SOCIAL media , *MEDICAL care costs , *PRE-exposure prophylaxis , *SURVEYS , *CONTROLLED release preparations , *LOW-income countries , *DESCRIPTIVE statistics , *RESEARCH funding , *MEN who have sex with men , *STATISTICAL sampling , *ODDS ratio , *DATA analysis software - Abstract
The recent approval of long-acting injectable cabotegravir (CAB-LA) as PrEP for HIV prevention could be an attractive alternative for MSM, particularly among those who face barriers to adherence using the oral pill. This study reports on the awareness of long-acting injectable PrEP (LAI-PrEP) and factors associated with interest in LAI-PrEP use among a nationwide sample of MSM in Malaysia. An online cross-sectional survey was conducted between August and September 2021 to explore perspectives on PrEP modalities among Malaysian MSM (N = 870). Convenience sampling was used to recruit participants using ads on two platforms hornet and facebook. While only 9.1% of the study participants were aware of LAI-PrEP, the majority had heard of oral PrEP (80.9%). After giving a description of it, a large majority (86.6%) expressed interest in using it if made accessible. Those who had a prior history of HIV testing (aOR = 1.9; 95% CI = 1.2–3.2) were more likely to use LAI-PrEP. Interestingly, despite the concerns related to potential high cost (aOR = 3.4; 95% CI = 2.1–5.5) and long-term side effects (aOR = 1.9; 95% CI = 1.2–3.1), the majority of the participants were interested in using LAI-PrEP. Those who were afraid of (or disliked) syringes were less interested in using it (aOR = 0.2; 95% CI; 0.1–0.4). In the recent context that LAI-PrEP was shown to be safe and effective at preventing HIV, our results indicate its potential relevance as an additional PrEP option that could accelerate the uptake and scale-up of PrEP. However, it is crucial to conduct future research urgently to improve the understanding of strategies that could enhance the accessibility, acceptability, and affordability of LAI-PrEP for MSM in low- and middle-income countries, including Malaysia. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
21. Contingency Management for Integrated Harm Reduction Among Men Who Have Sex with Men Who Use Methamphetamine in Los Angeles: A Pilot Assessment.
- Author
-
Blair, Cheríe S., Gandhi, Monica, Shoptaw, Steven, Blades, Christopher, and Clark, Jesse L.
- Subjects
HIV infection transmission ,PREVENTION of infectious disease transmission ,SUBSTANCE abuse prevention ,ANTIBIOTICS ,HIV prevention ,HIV infections ,PILOT projects ,DRUG efficacy ,RISK-taking behavior ,KRUSKAL-Wallis Test ,GONORRHEA ,COUNSELING ,TENOFOVIR ,HUMAN sexuality ,ANTIRETROVIRAL agents ,BLOOD collection ,FISHER exact test ,HARM reduction ,METHAMPHETAMINE ,PRE-exposure prophylaxis ,TREATMENT effectiveness ,RANDOMIZED controlled trials ,AIDS serodiagnosis ,REWARD (Psychology) ,DRUGS ,DESCRIPTIVE statistics ,CHI-squared test ,SEX customs ,RESEARCH funding ,MEN who have sex with men ,PATIENT compliance ,STATISTICAL sampling ,URINALYSIS ,CONTACT tracing ,DATA analysis software ,BEHAVIOR modification ,CHLAMYDIA infections - Abstract
Methamphetamine (MA) use is associated with HIV transmission among men who have sex with men (MSM) and lapses in medication adherence. Contingency Management (CM) is effective in reducing MA use, but studies of CM to support adherence to HIV prevention or treatment are limited. We conducted a pilot trial of a CM intervention to reduce MA use and improve PrEP/ART adherence among MSM prescribed a tenofovir (TFV)-based regimen for HIV prevention or treatment. Participants were randomly assigned to receive escalating incentives for either MA abstinence or TFV adherence (based on point-of-care urine testing), and to a monitoring schedule of either 2 or 3 visits/week for 4 weeks. 19 MSM were randomized to either CM for MA use or CM for PrEP/ART adherence (median age: 38; IQR: 28–46) and 15 were living with HIV. Participants attended 95.7% (67/70) of scheduled visits in the 2x/week arm and 74.8% (74/99) in the 3x/week arm. TFV adherence was higher among participants in the TFV adherence arm with 93.5% (n = 72/77) of urine samples positive for TFV, compared to 76.6% (n = 49/64) in the MA abstinence arm (p = 0.007). Participants in the MA abstinence arm had more urine samples negative for MA metabolites (20.3%, n = 13/64) than those receiving CM for TFV adherence (6.5%, n = 5/77; p = 0.021). A CM model for MA abstinence and PrEP/ART adherence using twice-weekly visits and urine testing for MA and TFV for MSM who use MA is feasible and potentially effective as an integrated harm reduction strategy. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
22. Same-Sex Marriage Laws, Provider-Patient Communication, and PrEP Awareness and Use Among Gay, Bisexual, and Other Men Who have Sex with Men in the United States.
- Author
-
Skinner, Alexandra, Stein, Michael D., Dean, Lorraine T., Oldenburg, Catherine E., Mimiaga, Matthew J., Chan, Philip A., Mayer, Kenneth H., and Raifman, Julia
- Subjects
HIV infection transmission ,PREVENTION of infectious disease transmission ,MARRIAGE law ,HIV prevention ,CONFIDENCE intervals ,HEALTH services accessibility ,HUMAN sexuality ,REGRESSION analysis ,SOCIAL stigma ,PRE-exposure prophylaxis ,HEALTH literacy ,COMMUNICATION ,DESCRIPTIVE statistics ,GOVERNMENT policy ,RESEARCH funding ,MEN who have sex with men ,PATIENT-professional relations ,GAY people ,SAME-sex marriage - Abstract
State-level structural stigma and its consequences in healthcare settings shape access to pre-exposure prophylaxis (PrEP) for HIV prevention among gay, bisexual, and other men who have sex with men (GBMSM). Our objective was to assess the relationships between same-sex marriage laws, a measure of structural stigma at the state level, provider-patient communication about sex, and GBMSM awareness and use of PrEP. Using data from the Fenway Institute's MSM Internet Survey collected in 2013 (N = 3296), we conducted modified Poisson regression analyses to evaluate associations between same-sex marriage legality, measures of provider-patient communication, and PrEP awareness and use. Living in a state where same-sex marriage was legal was associated with PrEP awareness (aPR 1.27; 95% CI 1.14, 1.41), as were feeling comfortable discussing with primary care providers that they have had sex with a man (aPR 1.63; 95% CI 1.46, 1.82), discussing with their primary care provider having had condomless sex with a man (aPR 1.65; 95% CI 1.49, 1.82), and discussing with their primary care provider ways to prevent sexual transmission of HIV (aPR 1.39; 95% CI 1.26, 1.54). Each of these three measures of provider-patient communication were additionally associated with PrEP awareness and use. In sum, structural stigma was associated with reduced PrEP awareness and use. Policies that reduce stigma against GBMSM may help to promote PrEP and prevent HIV transmission. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
23. Impact of Homophobia and Racism on Comfort Receiving Pre-exposure Prophylaxis at Various Locations Among Black MSM in Mississippi.
- Author
-
Haubrick, Kayla K., Whiteley, Laura, Arnold, Trisha, Leigland, Avery, Ward, Lori M., Brock, James B., and Brown, Larry K.
- Subjects
HIV prevention ,RACISM ,BLACK people ,HOMOPHOBIA ,MEDICAL care ,PRE-exposure prophylaxis ,T-test (Statistics) ,RESEARCH funding ,CHI-squared test ,DESCRIPTIVE statistics ,POSTAL service ,MEN who have sex with men ,SOCIODEMOGRAPHIC factors - Abstract
Pre-exposure prophylaxis (PrEP) is underutilized among Black men who have sex with men (BMSM) in the Southern United States. We assessed comfort receiving PrEP at various locations among 65 BMSM. Chi-square and t-tests explored associations between demographics, experienced homophobia and racism, and comfort receiving PrEP. BMSM with greater experienced homophobia were less comfortable at academically affiliated clinics [X
2 (2, N = 59) = 10.61, p = 0.01], CBOs [X2 (3, N = 59) = 10.02, p = 0.02], and STI/HIV clinics [X2 (3, N = 59) = 8.63, p = 0.04]. Those with greater experienced racism were more comfortable receiving PrEP by mail [X2 (3, N = 61) = 9.40, p = 0.02]. Homophobia and racism influence preferences of BMSM for where and how they receive PREP care. Private modes of PrEP delivery and interventions targeting provider and organizational bias should be explored. [ABSTRACT FROM AUTHOR]- Published
- 2023
- Full Text
- View/download PDF
24. Putting 2-1-1 into Practice: PrEP Users' Knowledge of Effectively Starting and Stopping Oral PrEP Use.
- Author
-
Rotsaert, Anke, Reyniers, Thijs, Vanhamel, Jef, Van Landeghem, Ella, Vanbaelen, Thibaut, Van Mieghem, Heleen, Nöstlinger, Christiana, Laga, Marie, and Vuylsteke, Bea
- Subjects
HIV prevention ,CONFIDENCE intervals ,HUMAN sexuality ,PRE-exposure prophylaxis ,HEALTH literacy ,SURVEYS ,SEX customs ,QUESTIONNAIRES ,RESEARCH funding ,PATIENT education ,SOCIODEMOGRAPHIC factors ,MEN who have sex with men ,ODDS ratio ,LOGISTIC regression analysis - Abstract
Starting and stopping oral HIV pre-exposure prophylaxis (PrEP) in a way that compromises its effectiveness should be avoided. Between September 2020 and June 2021, we assessed self-perceived and actual knowledge of effectively starting and stopping oral PrEP through an online survey among 206 PrEP users assigned male at birth in Belgium. We examined associations between incorrect start-and-stop knowledge and socio-demographics, sexual behaviour and PrEP use, using bi- and multi-variable logistic regression. The majority of men (84.9%) perceived their start-and-stop knowledge as 'very good', but only 62.1% of all men correctly indicated how to effectively start and stop with PrEP. Using PrEP daily [adjusted OR 2.12, 95% CI (1.06–4.28), p = 0.034] was significantly associated with incorrect start-and-stop knowledge. To enable PrEP users to effectively use PrEP, they need to be better informed about how to start and stop use, irrespective of the dosing regimen. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
25. Low incidence of HIV infection and decreasing incidence of sexually transmitted infections among PrEP users in 2020 in Germany.
- Author
-
Schmidt, Daniel, Kollan, Christian, Bartmeyer, Barbara, Bremer, Viviane, Schikowski, Tim, Friebe, Martin, Schellberg, Sven, Scholten, Stefan, Bickel, Markus, Hanhoff, Nikola, Rüsenberg, Robin, Schewe, Knud, Knechten, Heribert, Panstruga, Petra, Baumgarten, Axel, Reisenweber, Bianca, Hillenbrand, Heribert, Zucker, Kai, Köppe, Siegfried, and Da Silva Ribeiro, Marc
- Subjects
HIV infection epidemiology ,HIV prevention ,HIV infection risk factors ,CONFIDENCE intervals ,MULTIVARIATE analysis ,DISEASE incidence ,MEDICAL care costs ,ANTIRETROVIRAL agents ,TREATMENT duration ,PRE-exposure prophylaxis ,RISK assessment ,DRUGS ,HEALTH insurance ,RESEARCH funding ,GOVERNMENT aid ,MEN who have sex with men ,PATIENT compliance ,INSURANCE ,COVID-19 pandemic ,EVALUATION - Abstract
Introduction: Objectives of this study, as part of a nation-wide HIV pre-exposure prophylaxis (PrEP) evaluation project, were to determine the incidence of infections with HIV, chlamydia, gonorrhea, syphilis, hepatitis A/B/C in persons using PrEP, and to describe the health care funded PrEP use in Germany. Additionally, factors associated with chlamydia/gonorrhea and syphilis infections were assessed. Methods: Anonymous data of PrEP users were collected at 47 HIV-specialty centers from 09/2019–12/2020. Incidence rates were calculated per 100 person years (py). Using longitudinal mixed models, we analyzed risk factors associated with sexually transmitted infections (STIs). Results: 4620 PrEP users were included: 99.2% male, median age 38 years (IQR 32–45), 98.6% men who have sex with men (MSM). The median duration of PrEP exposure was 451 days (IQR 357–488), totaling 5132 py. Four HIV infections were diagnosed, incidence rate 0,078/100py (95% CI 0.029–0.208). For two, suboptimal adherence was reported and in the third case, suboptimal adherence and resistance to emtricitabine were observed. One infection was likely acquired before PrEP start. Incidence rates were 21.6/100py for chlamydia, 23.7/100py for gonorrhea, 10.1/100py for syphilis and 55.4/100py for any STI and decreased significantly during the observation period. 65.5% of syphilis, 55.6% of chlamydia and 50.1% of gonorrhea cases were detected by screening of asymptomatic individuals. In a multivariable analysis among MSM younger age, PrEP start before health insurance coverage and daily PrEP were associated with greater risk for chlamydia/gonorrhea. Symptom triggered testing and a history of STI were associated with a higher risk for chlamydia/gonorrhea and syphilis. A significantly lower risk for chlamydia/gonorrhea and syphilis was found for observations during the COVID-19 pandemic period. Conclusions: We found that HIV-PrEP is almost exclusively used by MSM in Germany. A very low incidence of HIV infection and decreasing incidence rates of STIs were found in this cohort of PrEP users. The results were influenced by the SARS-CoV-2 pandemic. Rollout of PrEP covered by health insurance should be continued to prevent HIV infections. Increased PrEP availability to people at risk of HIV infection through the elimination of barriers requires further attention. Investigation and monitoring with a longer follow-up would be of value. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
26. Between- and Within-Individual Sociodemographic and Psychological Determinants of PrEP Adherence Among Men Who have Sex with Men Prescribed a Daily PrEP Regimen in Wales.
- Author
-
Gillespie, David, de Bruin, Marijn, Hughes, Dyfrig A., Ma, Richard, Williams, Adam, Wood, Fiona, Couzens, Zoë, Jones, Adam, and Hood, Kerenza
- Subjects
SEXUALLY transmitted disease diagnosis ,HIV prevention ,ANTI-HIV agents ,RISK-taking behavior ,SOCIAL determinants of health ,HUMAN sexuality ,PRE-exposure prophylaxis ,DRUGS ,HEALTH attitudes ,HEALTH behavior ,SEX customs ,RESEARCH funding ,MEN who have sex with men ,SOCIODEMOGRAPHIC factors ,PATIENT compliance ,ANAL sex ,CONDOMS ,INSURANCE ,HEALTH promotion - Abstract
We investigated the determinants of daily PrEP use and coverage of condomless anal sex (CAS) by PrEP among men who have sex with men in Wales, UK. We measured PrEP use by electronic monitors and CAS by secure online surveys. We defined PrEP use based on daily medication cap openings and coverage as CAS episodes preceded by ≥ 3 days of PrEP use and followed by ≥ 2 days of PrEP use. We included 57 participants (5463 observations). An STI diagnosis was associated with lower PrEP use but also lower PrEP coverage. Older adults had higher PrEP use. A belief that other PrEP users took PrEP as prescribed was associated with lower PrEP coverage. An STI diagnosis is an important cue for an intervention, reflecting episodes of high-risk sexual behaviour and low PrEP coverage. Other results provide a basis for the development of an evidence-informed intervention for promoting coverage of PrEP. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
27. Effects of a Parent-Focused HIV Prevention Intervention for Young Men Who have Sex with Men: A Pilot Randomized Clinical Trial.
- Author
-
Huebner, David M., Barnett, Andrew P., Baucom, Brian R. W., and Guilamo-Ramos, Vincent
- Subjects
HIV prevention ,PILOT projects ,FOCUS groups ,CONFIDENCE intervals ,INTERNET ,MEDICAL care ,INTERVIEWING ,HEALTH outcome assessment ,SEX education ,PARENTING ,RANDOMIZED controlled trials ,PRE-exposure prophylaxis ,COMPARATIVE studies ,DESCRIPTIVE statistics ,RESEARCH funding ,MEN who have sex with men ,STATISTICAL sampling ,SOCIODEMOGRAPHIC factors ,ODDS ratio ,SEXUAL health ,GAY men - Abstract
Copyright of AIDS & Behavior is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2023
- Full Text
- View/download PDF
28. Challenges with PrEP Uptake and Adherence Among Gay, Bisexual, and Other Men Who Have Sex with Men in Kisumu, Kenya.
- Author
-
Graham, Susan M., Okall, Duncan O., Mehta, Supriya D., Obondi, Eve, Ng'ety, George, Ochieng, Elijah, Jadwin-Cakmak, Laura, Amico, K. Rivet, Harper, Gary W., Bailey, Robert C., and Otieno, Fredrick O.
- Subjects
HIV infection epidemiology ,HIV prevention ,BISEXUALITY ,RESEARCH ,HIV infections ,HEALTH services accessibility ,HUMAN sexuality ,RESEARCH methodology ,TENOFOVIR ,SELF-evaluation ,PRE-exposure prophylaxis ,HOMOSEXUALITY ,SEXUAL minorities ,SEX customs ,DRUGS ,RESEARCH funding ,PATIENT compliance ,LONGITUDINAL method - Abstract
Copyright of AIDS & Behavior is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2023
- Full Text
- View/download PDF
29. Changes in high-risk sexual behavior, HIV and other STI testing, and PrEP use during the COVID-19 pandemic in a longitudinal cohort of adolescent men who have sex with men 13 to 18 years old in the United States.
- Author
-
Hong, Chenglin, Huh, David, Schnall, Rebecca, Garofalo, Robert, Kuhns, Lisa M., Bruce, Josh, Batey, D. Scott, Radix, Asa, Belkind, Uri, Hidalgo, Marco A., Hirshfield, Sabina, and Pearson, Cynthia R.
- Subjects
PREVENTION of sexually transmitted diseases ,HIV prevention ,RISK-taking behavior ,HUMAN sexuality ,MEDICAL screening ,PRE-exposure prophylaxis ,MEDICAL care use ,HEALTH behavior ,RESEARCH funding ,MEN who have sex with men ,HEALTH equity ,COVID-19 pandemic ,LONGITUDINAL method ,TELEMEDICINE ,ADOLESCENCE - Abstract
Copyright of AIDS & Behavior is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2023
- Full Text
- View/download PDF
30. Development and Validation of the Youth Pre-Exposure Prophylaxis (PrEP) Stigma Scale.
- Author
-
Budhwani, Henna, Yiğit, İbrahim, Maragh-Bass, Allysha C., Rainer, Crissi B., Claude, Kristina, Muessig, Kathryn E., and Hightow-Weidman, Lisa B.
- Subjects
HIV prevention ,HIV infection risk factors ,EXPERIMENTAL design ,RESEARCH evaluation ,RESEARCH methodology ,RESEARCH methodology evaluation ,ATTITUDE (Psychology) ,COMING out (Sexual orientation) ,SOCIAL stigma ,ANTIRETROVIRAL agents ,PRE-exposure prophylaxis ,CRONBACH'S alpha ,RISK perception ,RESEARCH funding ,SEXUAL minorities ,DESCRIPTIVE statistics ,FACTOR analysis ,PSYCHOSOCIAL factors ,STATISTICAL correlation ,MEN who have sex with men ,TRANSGENDER people ,ADULTS ,ADOLESCENCE - Abstract
Copyright of AIDS & Behavior is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2023
- Full Text
- View/download PDF
31. Determinants of Willingness to Use PrEP Among Gay and Bisexual Men in China Before Implementation: A Structural Equation Modeling Assessment.
- Author
-
Cui, Tracy Shicun, Lane, Benjamin, Wu, Yumeng, Ma, Jing, Fu, Rong, Hou, Jianhua, Meng, Siyan, Xie, Lu, Gu, Yuzhou, Huang, Xiaojie, Zheng, Huang, Ma, Yanling, He, Na, and Meyers, Kathrine
- Subjects
HIV prevention ,THERAPEUTICS ,STRUCTURAL equation modeling ,ATTITUDE (Psychology) ,SOCIAL networks ,SOCIAL norms ,PRE-exposure prophylaxis ,SURVEYS ,HEALTH literacy ,HEALTH attitudes ,RESEARCH funding ,MEN who have sex with men ,GAY people - Abstract
With the recent endorsement of PrEP by the Chinese government, research is urgently needed to better understand factors impacting PrEP uptake among gay, bisexual, and other men who have sex with men (GBMSM) in China. This study examined willingness to use PrEP for HIV prevention among GBMSM in China through structural equation modeling. We examined the relationship among PrEP-related attitudes, subjective norms, PrEP-related knowledge and beliefs about medicines and willingness to use PrEP. The analysis showed a good fit between the data and both the measurement model (RMSEA = 0.060) and structural model (RMSEA = 0.054). Knowledge, attitudes, and subjective norms were significantly related to intention to use PrEP, whereas the effect of general beliefs about medicines was insignificant. These effect mechanisms point to the importance of designing interventions to support PrEP uptake that target knowledge, enhance positive attitudes about PrEP within social networks, and build positive social norms around PrEP among sexually active GBMSM. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
32. Randomized Controlled Trial of Automated Directly Observed Therapy for Measurement and Support of PrEP Adherence Among Young Men Who have Sex with Men.
- Author
-
Buchbinder, Susan P., Siegler, Aaron J., Coleman, Kenneth, Vittinghoff, Eric, Wilde, Gretchen, Lockard, Annie, Scott, Hyman, Anderson, Peter L., Laborde, Nicole, van der Straten, Ariane, Christie, Richard H., Marlborough, Michelle, and Liu, Albert Y.
- Subjects
CLINICAL drug trials ,HIV prevention ,EVALUATION of medical care ,DIRECTLY observed therapy ,HEALTH care reminder systems ,MOBILE apps ,TENOFOVIR ,SELF-evaluation ,ARTIFICIAL intelligence ,PRE-exposure prophylaxis ,DIARY (Literary form) ,RANDOMIZED controlled trials ,DESCRIPTIVE statistics ,RESEARCH funding ,MEN who have sex with men ,PATIENT compliance ,STATISTICAL sampling ,EMTRICITABINE - Abstract
Copyright of AIDS & Behavior is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2023
- Full Text
- View/download PDF
33. URCHOICE: Preferences for Pre-Exposure Prophylaxis (PrEP) Options for HIV Prevention Among Kenyan men who have sex with men and Transgender Women in Nairobi, Kisumu and the Coast.
- Author
-
Bailey, Robert C., Kimani, Makobu, Kabuti, Rhoda, Gumbe, Edwin, Otieno, George, Kimani, Joshua, Okall, Duncan, Sanders, Eduard J., and Otieno, Fredrick O.
- Subjects
HIV prevention ,DRUG administration routes ,HIV seronegativity ,DRUG tablets ,INJECTIONS ,TRANS women ,INTERVIEWING ,CONTROLLED release drugs ,PATIENTS' attitudes ,PRE-exposure prophylaxis ,SYMPTOMS ,RESEARCH funding ,MEN who have sex with men ,CONDOMS - Abstract
HIV prevention method preferences were evaluated among Kenyan men who have sex with men (MSM) and transgender women (TW) from three sites: Kisumu, Nairobi and the Coast. Information sessions detailing the attributes, duration of protection, route of administration and probable visibility were attended by 464 HIV negative participants, of whom 423 (median age: 24 years) agreed to be interviewed. Across pairwise comparisons daily PrEP was by far the least preferred (1%); quarterly injections (26%) and monthly pills (23%) were most preferred, followed by yearly implant (19%) and condoms (12%). When participants were "forced" to choose their most preferred PrEP option, only 10 (2.4%) chose the daily pill; more (37.1%) chose the quarterly injection than the monthly pill (34.8%) and the yearly implant (25.8%). TW preferred the yearly implant over the quarterly injection. To achieve the rates of PrEP uptake and adherence necessary for protecting large proportions of vulnerable MSM and TW, a variety of long-acting products should be developed and made accessible to appeal to a diversity of preferences. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
34. PrEP Interest Among Men Who Have Sex with Men in the Netherlands: Covariates and Differences Across Samples.
- Author
-
van Dijk, Mart, Duken, Sascha B., Delabre, Rosemary M., Stranz, Richard, Schlegel, Vincent, Rojas Castro, Daniela, Bernier, Adeline, Zantkuijl, Paul, Ruiter, Robert A. C., de Wit, John B. F., and Jonas, Kai J.
- Subjects
- *
PRE-exposure prophylaxis , *MEN who have sex with men , *HIV prevention , *SEXUAL orientation , *REGRESSION analysis , *RISK-taking behavior , *RESEARCH , *HUMAN sexuality , *RESEARCH methodology , *EVALUATION research , *MEDICAL cooperation , *HOMOSEXUALITY , *COMPARATIVE studies , *RESEARCH funding - Abstract
Despite increased availability of pre-exposure prophylaxis (PrEP), PrEP uptake has remained low. To promote uptake, factors related to PrEP interest among relevant target populations warrant investigation. The aim of this study was to provide an analysis of PrEP interest among men who have sex with men (MSM) in the Netherlands, while taking study recruitment strategies into account. We recruited 154 MSM from an LGBT research panel (AmsterdamPinkPanel) and 272 MSM from convenience sampling. Both samples were part of the Flash! PrEP in Europe Survey and were compared on their PrEP interest, usage intentions, and sexual behavior. We conducted logistic regression analyses to discover variables associated with PrEP interest and intentions. Participants from the AmsterdamPinkPanel were less likely to use PrEP, had less knowledge of PrEP, and were less interested in PrEP than participants from convenience sampling. Significant covariates of PrEP interest were being single, more prior PrEP knowledge, sexual risk behaviors, such as not having used a condom during last sex and having ever used drugs in a sexual context, and not participating in the AmsterdamPinkPanel. Adding the recruitment strategy to the regression increased explained variance on top of predictors already described in the literature. Increased sexual risk behavior is related to increased PrEP interest and it helps to identify PrEP target groups. Recruitment strategies have a substantial impact on findings regarding PrEP interest and usage intentions. This study emphasizes the importance of using multiple strategies for recruiting participants to obtain a more comprehensive view of MSM's attitudes toward PrEP. [ABSTRACT FROM AUTHOR]
- Published
- 2020
- Full Text
- View/download PDF
35. Defining Sexual Risk in the Era of Biomedical HIV Prevention: Implications for HIV Research and Practice.
- Author
-
Horvath, Keith J., Lammert, Sara, Martinka, Aldona, and Erickson, Darin
- Subjects
- *
MEN who have sex with men , *PRE-exposure prophylaxis , *VIRAL load , *CONDOM use , *HIV infections , *HIV prevention , *RISK-taking behavior , *HUMAN sexuality , *PSYCHOSOCIAL factors , *RESEARCH funding , *SEXUAL partners - Abstract
Advancing HIV behavioral science and its integration with recent biomedical prevention strategies-treatment as prevention and pre-exposure prophylaxis (PrEP)-is complicated because traditional definitions of sexual risk (condomless anal sex [CAS] or CAS with a serodiscordant partner) may not suffice given the success of biomedical prevention in the absence of condoms. To better understand how to define and understand risk in the era of biomedical HIV prevention, we assessed correlates of four different definitions of high-risk sexual behavior among a sample of 401 adult HIV-positive MSM (57% African American) residing in the New York City area: (1) a traditional model of risk defined as CAS with an HIV-negative or unknown serostatus partner; (2) a definition that considered participant viral load (VL); (3) a definition that considered partner PrEP use; and (4) a definition that considered participant HIV VL and partner PrEP use. Among participants reporting anal sex (n = 281) with a man in the past 3 months, 42% were considered high risk under Definition 1, 6% under Definition 2, 25% under Definition 3, and 2% under Definition 4. Correlates of risk varied across definitions. For example, while education was the strongest predictor of high-risk sexual behavior in Definitions 1 and 2, alcohol use and enacted stigma were the strongest predictors in the model that only accounted for partner PrEP use (Definition 3). These findings have implications for whom to reach for intervention efforts, the difficulty in meeting recruitment goals, and the types of interventions that should be used. [ABSTRACT FROM AUTHOR]
- Published
- 2020
- Full Text
- View/download PDF
36. Navigating the Long Road Forward for Maximizing PrEP Impact Among Adolescent Men Who Have Sex with Men.
- Author
-
Huebner, David M. and Mustanski, Brian
- Subjects
- *
PRE-exposure prophylaxis , *HIV prevention , *MEN who have sex with men , *SEXUAL orientation , *TEENAGERS' sexual behavior , *HOMOSEXUALITY , *RESEARCH funding - Abstract
Preexposure prophylaxis (PrEP) has tremendous potential to decrease new HIV infections among populations at high risk, such as men who have sex with men (MSM). That potential is already becoming realized among adult MSM, where PrEP uptake has increased rapidly in the past several years. However, expanding PrEP access to adolescent MSM (AMSM) will be more challenging. This commentary reviews the existing scientific literature relevant to PrEP use for AMSM and highlights critical areas in need of further attention before PrEP is likely to impact the HIV epidemic among adolescents. We highlight concerns that need to be addressed in the areas of (1) achieving adequate coverage of PrEP in the adolescent population, (2) increasing awareness and access, (3) supporting adherence and maintenance, and (4) ensuring that PrEP does not perpetuate existing disparities. Across all of these domains, we highlight the central roles of parents and healthcare providers in supporting AMSM PrEP utilization. Finally, we suggest a number of areas of future research that must be addressed before PrEP is likely to see wide implementation among AMSM. [ABSTRACT FROM AUTHOR]
- Published
- 2020
- Full Text
- View/download PDF
37. Role of Social and Sexual Network Factors in PrEP Utilization Among YMSM and Transgender Women in Chicago.
- Author
-
Phillips II, Gregory, Neray, Balint, Birkett, Michelle, Felt, Dylan, Janulis, Patrick, Mustanski, Brian, and Phillips, Gregory 2nd
- Subjects
- *
SOCIAL networks , *HIV infections , *SOCIAL factors , *PRE-exposure prophylaxis , *BLACK men , *MEN who have sex with men , *HIV prevention , *PREVENTIVE health services , *HOMOSEXUALITY , *SAFE sex , *RESEARCH funding - Abstract
Despite demonstrated efficacy, uptake of HIV pre-exposure prophylaxis (PrEP) remains low, particularly among high-risk demographics such as transgender women, Black men who have sex with men (BMSM), and young MSM (YMSM). Research thus far has largely focused on individual factors that may impede PrEP uptake in these demographics, leaving social network factors relatively unexplored. The present study used data collected from participants within RADAR, a longitudinal cohort study in Chicago focused on understanding the individual, dyadic, network, social, and biologic factors associated with HIV infection within YMSM. Of the 906 study participants who did not report an HIV diagnosis at baseline, 7.0% reported using PrEP in the prior 6 months. Recent PrEP use was associated with both individual-level (age and gender) and network-level factors (mean relationship strength, sexual network degree, etc.). These findings highlight the need to expand beyond focusing on individual-level drivers of PrEP uptake, as well as changing our understanding of who is most important within a network (centrality vs. strength of weak ties). Future work is needed to determine whether variables associated with PrEP uptake are similarly connected to PrEP adherence. [ABSTRACT FROM AUTHOR]
- Published
- 2019
- Full Text
- View/download PDF
38. Prevalence and Correlates of PrEP Awareness and Use Among Black Men Who Have Sex with Men and Women (MSMW) in the United States.
- Author
-
Friedman, M. Reuel, Sang, Jordan M., Bukowski, Leigh A., Chandler, Cristian J., Egan, James E., Eaton, Lisa A., Matthews, Derrick D., Ho, Ken, Raymond, Henry F., and Stall, Ron
- Subjects
HIV prevention ,SEXUALLY transmitted disease diagnosis ,BISEXUALITY ,BLACK people ,HEALTH services accessibility ,HEALTH status indicators ,INTELLECT ,PREVENTIVE medicine ,PUBLIC health ,RESEARCH funding ,LOGISTIC regression analysis ,HIV seroconversion ,MEN who have sex with men ,DESCRIPTIVE statistics ,HIV seronegativity ,EPIDEMIOLOGY - Abstract
Copyright of AIDS & Behavior is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2019
- Full Text
- View/download PDF
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.