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The superiority of BWM over other weighting methods for obtaining the weight values of the attributes is that it achieves high-confidence results with a reasonable number of pairwise comparisons. Although the best-worst method (BWM) is a well-known multi-criteria decision-making (MCDM) method that has been successfully utilized in almost all scientific areas to solve challenging real-life problems, no research has comprehensively examined the state-of-the-art in this regard. The present study depicts a detailed overview of publications concerned with BWM during the period 2015–2022. Based on the information obtained from the Scopus database, this work presents a big picture of current research on BWM. In other words, this paper analyzes the existing literature about BWM and identifies thematic contexts, application areas, emerging trends, and remaining research gaps to shed light on future research agendas aligning with those gaps. Further, the most recent BWM research is analyzed in the top ten scientific areas, from engineering to materials science. “Engineering”, “computer science”, and “business, management, and accounting” are the hottest fields of BWM research. China is the most active country regarding “engineering” and “computer science”, whereas India is the leader in “business, management, and accounting”. The study also reveals that there are still many research gaps in BWM research. The big picture taken in this study will not only showcase the current situation of BWM research but will also positively impact the direction and quality of new research. [ABSTRACT FROM AUTHOR]

A drug molecule is a substance that changes an organism's mental or physical state. Every approved drug has an indication, which refers to the therapeutic use of that drug for treating a particular medical condition. While the Large Language Model (LLM), a generative Artificial Intelligence (AI) technique, has recently demonstrated effectiveness in translating between molecules and their textual descriptions, there remains a gap in research regarding their application in facilitating the translation between drug molecules and indications (which describes the disease, condition or symptoms for which the drug is used), or vice versa. Addressing this challenge could greatly benefit the drug discovery process. The capability of generating a drug from a given indication would allow for the discovery of drugs targeting specific diseases or targets and ultimately provide patients with better treatments. In this paper, we first propose a new task, the translation between drug molecules and corresponding indications, and then test existing LLMs on this new task. Specifically, we consider nine variations of the T5 LLM and evaluate them on two public datasets obtained from ChEMBL and DrugBank. Our experiments show the early results of using LLMs for this task and provide a perspective on the state-of-the-art. We also emphasize the current limitations and discuss future work that has the potential to improve the performance on this task. The creation of molecules from indications, or vice versa, will allow for more efficient targeting of diseases and significantly reduce the cost of drug discovery, with the potential to revolutionize the field of drug discovery in the era of generative AI. [ABSTRACT FROM AUTHOR]