1. 15-Year follow-up of regional right and left ventricular function after the Senning operation: a Colour-Doppler myocardial imaging study
- Author
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Ana Moya, Benedicte Eyskens, Alexander Van De Bruaene, Frank Weidemann, Pieter De Meester, Els Troost, Piet Claus, Leen Roggen, Werner Budts, and Philip Moons
- Subjects
medicine.medical_specialty ,Cardiac & Cardiovascular Systems ,Heart Ventricles ,senning procedure ,Color ,heart failure ,SYSTEMIC RIGHT VENTRICLE ,030204 cardiovascular system & hematology ,Ventricular Function, Left ,PULMONARY-HYPERTENSION ,ATRIAL REPAIR ,03 medical and health sciences ,atrial switch procedure ,0302 clinical medicine ,Internal medicine ,MAGNETIC-RESONANCE ,medicine ,Humans ,030212 general & internal medicine ,Transposition of great vessels ,Senning operation ,STRAIN-RATE ,Science & Technology ,Ventricular function ,business.industry ,GREAT-ARTERIES ,ADULTS ,General Medicine ,medicine.disease ,Myocardial imaging ,Right ventricular dysfunction ,Arterial Switch Operation ,Cross-Sectional Studies ,Heart failure ,TRANSPOSITION ,Ventricular Function, Right ,Cardiovascular System & Cardiology ,cardiovascular system ,Cardiology ,Colour doppler ,right ventricular dysfunction ,HEART ,Senning Procedure ,ECHOCARDIOGRAPHY ,Cardiology and Cardiovascular Medicine ,business ,Life Sciences & Biomedicine ,Follow-Up Studies - Abstract
INTRODUCTION: Despite right ventricular (RV) dysfunction being a major concern in Senning patients, long-term follow-up data is lacking. This study aimed (1) at evaluating regional (base-mid-apex) RV and left ventricular (LV) function using Colour-Doppler myocardial imaging over a 15-year follow-up period and (2) at comparing results with matched controls. METHODS: For the longitudinal analysis (2004-2019), we compared systolic and diastolic function in 10 Senning patients. For the cross-sectional analysis, we compared the subaortic RV (sRV) of Senning patients with the RV and LV of matched controls and the subpulmonary LV (spLV) of Senning patients with the LV of matched controls. RESULTS: The longitudinal analysis of sRV function showed a significant decrease in apical peak systolic strain (-17 ± 7% vs -12 ± 4%; p = 0.025) and apical peak systolic strain rate (-1.1 ± 0.3s-1 vs -0.8 ± 0.4s-1; p = 0.012). spLV function showed a significant decrease in peak systolic velocity (mid; p = 0.013 and apex; p = 0.011) and peak systolic strain rate (mid; p = 0.048). The cross-sectional analysis revealed significant lower values for basal, mid and apical peak systolic velocity, peak systolic strain rate, peak systolic strain of the sRV of Senning patients when compared to both LV and RV of matched controls (all p
- Published
- 2020
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