Search

Anaplastic Oligodendroglioma has a better prognosis in the presence of 1p19q co-deletion and IDH-1 mutation but spinal leptomeningeal dissemination of cerebral anaplastic oligodendroglioma is a rare occurrence. We describe the case of a 47 year old man with spinal leptomeningeal dissemination eight months after resection of an anaplastic cerebral oligodendroglioma presenting with encephalitic features. We present the radiological, biochemical, intraoperative and histological features of this syndrome. Despite resolution of symptoms with corticosteroid treatment and favourable biochemical markers, prognosis remains poor when spinal leptomeningeal disease is present.

A 29-year-old male patient presented to us with multiple swellings on his left leg associated with localized sweating and occasional throbbing pain. Based on the clinical features and histopathology, a diagnosis of Eccrine angiomatous hamartoma was made. The patient showed good response with regression of lesions after four intralesional injections of ethoxysclerol (polidocanol). We present this as a case of late onset eccrine angiomatous hamartoma with multiple lesions, responding to treatment with intralesional ethoxysclerol.