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In order to locate faults in the double-terminal DC distribution network, the DC circuit breaker and bidirectional thyristor are used to obtain the boundary capacitor voltage recording, and the equivalent time constant is extracted through the capacitor voltage recording of different fault distances. Obtain the relationship curve between different equivalent time constants and fault distance, so as to realize fault location. The simulation results show that the positioning error accuracy is within 1%.

Nasopharyngeal carcinoma (NPC) is a distinct head and neck cancer, which is occurring at a high frequency in Southern China. Emerging studies have shown that long noncoding RNAs (lncRNAs) play a critical role in carcinogenesis and progression. In this study, we established a comprehensive lncRNA profile in NPC and found that 35 lncRNAs were differentially expressed in NPC. We found that LINC0086 was decreased in NPC patient serum samples and tissues. The KaplanMeier survival curve showed that patients with high LINC0086 expression had a higher survival rate than those with low LINC0086 expression. LINC0086 expression was associated with NPC histological grade, lymph node metastasis, and clinical stage. Upregulation of LINC0086 inhibited cancer cell proliferation and promoted apoptosis. In addition, upregulation of LINC0086 dramatically decreased the expression of miR-214, an oncogene in several cancers, in C666-1 and HK-1 cells. An miR-214 binding site was found in the 3-UTR of LINC0086. We also validated that both miR-214 and LINC0086 presented in the RISC complex, demonstrating that LINC0086 could decrease miR-214 expression by directly interacting with miR-214. Furthermore, the suppressive effects of LINC0086 on NPC cell growth were reversed by overexpression of miR-214 in vitro and in vivo. Thus, our study reports a novel mechanism underlying NPC carcinogenesis and provides a potential novel diagnosis and treatment biomarker for NPC.

To improve the accuracy of the network security situation, a security situation automatic prediction model based on accumulative data preprocess and support vector machine (SVM) optimized by covariance matrix adaptive evolutionary strategy (CMA-ES) is proposed. The proposed model adopts SVM which has strong nonlinear ability. Also, the hyper parameters for SVM are optimized through the CMA-ES which owns good performance in finding optimization automatically. Considering the irregularity of network security situation values, we accumulate the original sequence, so that the internal rules of discrete data can be revealed and it is easy to model. Simulation experiments show that the proposed model has faster convergence-speed and higher prediction accuracy than other extant prediction models.

There are a lot of security issues in block cipher algorithm. Security analysis and enhanced design of a dynamic block cipher was proposed. Firstly, the safety of ciphertext was enhanced based on confusion substitution of S-box, thus disordering the internal structure of data blocks by four steps of matrix transformation. Then, the diffusivity of cipher-text was obtained by cyclic displacement of bytes using column ambiguity function. The dynamic key was finally generated by using LFSR, which improved the stochastic characters of secret key in each of round of iteration. The safety performance of proposed algorithm was analyzed by simulation test. The results showed the proposed algorithm has a little effect on the speed of encryption and decryption while enhancing the security. Meanwhile, the proposed algorithm has highly scalability, the dimension of S-box and the number of register can be dynamically extended according to the security requirement.

Objective To assess the clinical effect and safety of direct current (DC) pulse produced by Han's Acupoint Nerve Stimulator in reduction (HANS) of labor pain. Methods Totally 120 participants were enrolled in this clinical trial, and were randomly divided into 4 groups including: HANS group, patient controlled intravenous analgesia (PCIA) group, patient-controlled epidural analgesia (PCEA) group and control group. The HANS group was treated by stimulating the acupoints of JiaJi (T10-L3) and Ciliao (BL 32) with DC pulse of 100 Hz and 15-30 mA produced by a portable battery-powered Han's Acupoint Nerve Stimulator for 30 min. The PCIA group was intravenously infused Ondansetron (8 mg) for 5 min, then tramadol injection (1.5 mg/kg) was slowly dripped by using BaxterAP II electronic pump with 50 mL tramadol (0.70%) + ondansetron (8 mg), background infusion 2 mL/h, PCA dose of 2 mL, lockout interval of 10 min. In PCEA group, women received intrathecal injection ropivacaine (3 mg) in L2-3, and epidural catheter was connected to BaxterAP II electronic pump, with 100 mL Ropivacaine (0.1%) and Sufentanil (50 ug), background infusion 5 mL, Patient controlled analgesia (PCA) dose of 5 mL, lockout interval of 10 min. The control group was not received analgesia. The visual analogue scale (VAS), stage and manner of labor, Apgar score of newborn, neonatal weights, oxytocin dosage, postpartum hemorrhage and side effects were monitored in all groups. Results The vital signs were all stable in the four analgesic groups. After analgesia, there was statistical difference in VAS score between HANS group and control group, between PCEA group and the control group, between PCIA group and control group. The analgesic effect in the PCEA group was significantly better than that of other two groups. The second stage of labor in the PCEA group was longer than the other three groups, showing significant difference between them. The Apgar score of newborn 1min after birth in the PCIA group was slightly lower than that of the other two groups, showing significant difference between them. The neonatal weights between four groups were not significantly different. The rate of cesarean section in the control group was significantly higher than that of the labor analgesia group, there was statistically difference in four groups. The number of PCIA group that used oxytocin was lower than that of other three groups. There was no significant difference in postpartum hemorrhage between four groups. The side effects of the PCEA group were itching, uroschesis and neonatal asphyxia and PCIA group were nausea and vomiting and neonatal asphyxia. However, fewer side effects were observed in the HANS group. Conclusion The DC pulse produced by HANS may be a non-pharmacological alternative to labor pain with fewer side effects.

This paper proposed a cognitive model for Ad hoc network, and combined formal modeling of cognitive model with quantitative analysis of cognitive performance, thus at the same time of formal modeling through quantitative analysis obtained Ad hoc network cognitive performance parameters.

A method of autonomous recoverment for survivable system was proposed. Firstly, failure models of survivable system were formally described based on stochastic Petri nets, in which a number of measurable index parameters for recoverment were also given out. And then a recursive autonomous recoverment strategy was presented,Compared with the traditional cyclical recovery strategy, recoverment strategies reduced the time and costs of emergency recovery.