1. Anti-Obesity Effects of Lactic Acid Bacteria-Fermented Dioscoreae Rhizoma Powder on High Fat Diet-Fed Animal Model
- Author
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Yang Gyu Kang, Hee Jeong Kim, Oh Hong Geun, Sang Wang Lee, Hak Yong Lee, Young Mi Park, Young Pill Kim, Seung Hwan Jang, and Hong Sig Sin
- Subjects
Materials science ,biology ,Normal diet ,food and beverages ,biology.organism_classification ,medicine.disease ,Obesity ,Lactic acid ,chemistry.chemical_compound ,Ballooning degeneration ,Functional food ,chemistry ,Adipocyte ,medicine ,Fermentation ,Food science ,Bacteria - Abstract
The purpose of this study was to examine the antiobesity effects of lactic acid bacteria-fermented Dioscoreae Rhizoma powder (LDR) in Sprague-Dawley rats with high-fat diet (HFD)-induced obesity. Rats were divided into 5 groups: normal diet group, control (high fat diet-vehicle) group, 0.4 g/kg LDR (high fat diet + 0.4 g/kg lactic acid bacteria-fermented Dioscoreae Rhizoma powder) group, 1 g/kg LDR (high fat diet + lactic acid bacteria-fermented Dioscoreae Rhizoma powder) group, 2.5g/kg LDR (high fat diet + lactic acid bacteria-fermented Dioscoreae Rhizoma powder) group. Our results indicate that LDR administration has effects on decreasing of body weight, fat weight, blood parameters and adipocyte size in the obesity animals. In addition, verified that fat degeneration and ballooning degeneration were alleviated in the experimental group fed on a high fat diet combined with LDR groups. These results indicate that lactic acid bacteria-fermented Dioscoreae Rhizoma powder may reduce elevating body weight and lipid accumulation in rat fed a high fat diet, suggesting its usefulness as a functional food for reducing body fat and obesity.
- Published
- 2015