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Additional file 1: Fig. S1. Inhibition of growth and TET2, and cell cycle arrest by T-dCyd in human solid tumor cell lines. Fig. S2. Effects of T-dCyd on DNMT3A/TET2-mutant NCI-H23 xenograft tumors in mice treated with 2 mg/kg T-dCyd by immunohistochemical and microscopic analyses (6 tumor samples per group). Fig. S3. Effects of T-dCyd on the induction of apoptosis in NCI-H23 cells. Fig. S4. Effects of T-dCyd on TET2 expression in DNMT3A/TET2-mutant NCI-H23 xenograft tumors.