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The sustainable development of forestry resources has attracted more and more attention from countries all over the world. In order to explore the research status, hot spots and development trends of forestry resources research, Bibliometrix and Biblioshiny, a bibliometric tool, were used to analyze the relevant literature in the field of forestry machinery included in the core collection of Web of Science from 2000 to 2022. The quantitative and visual analysis was carried out from five aspects: annual publication quantity, research institutions and their countries, journal sources, main authors and keywords. The results of the study show that: (1) Since 2000, the number of publications in forestry machinery research has increased exponentially, but it is still less than that of other industries; (2) European and American countries have paid more attention to forestry machinery research and are at the leading international level; (3) The mainstream journals in this field include Croatian Journal of Forest Engineering, Forests, Forest Ecology and Management, etc; (4) The scholars with more research include Spinelli R, Dickey JP, Horn R, Marchi E, Picchio R, and Uusitalo J; (5) In the past 20 years, the research hotspots of forestry machinery has shifted from forest management, logging, biomass, ergonomics, soil compaction, etc. , to agricultural machinery as well as productivity and precision forestry, reflecting the development trend of forestry machinery from extensive forestry to refined forestry. In the future, China needs to increase its investment in the field of forestry machinery, pay attention to and carry out cooperative research on forestry machinery with developed countries in Europe and the USA. This study can provide reference for researchers to grasp the research status, hot issues and development trends of forestry machinery, and provide basis for further research.

With the growing sophistication of cloning technology, rescuing cell resources is of great significance for the protection of endangered animals. The Yangtze sturgeon (Acipenser dabryanus), one of the three Acipenseriformes species in the Yangtze River, is critically endangered. Natural reproduction of the Yangtze sturgeon has not been detected since 2000. Less than 20 wild individuals are kept in husbandry, and all are too old to breed. Therefore, it is urgent to rescue the genetic resources of every wild Yangtze sturgeon. Here, we isolated and preserved viable cells from critically endangered postmortem Yangtze sturgeon for the first time. Attempts to rescue and preserve cell resources were carried out from 8 tissues, brain, kidney, gonad, fin, liver, skin, spleen, and muscle of an over 35-year-old female wild Yangtze sturgeon between 11 and 14 hours after death at 19.8°C in an outdoor concrete pond, and only muscle tissue cells could be successfully subcultured and preserved. Furthermore, the cultured cells showed high post-thaw cell viability and normal growth with a population doubling time of 52.98 h. Moreover, they were fibronectin- and desmin-positive, characterizing them as fibroblastic confirmed muscle cells with fibroblastic properties and myogenic origin. Tests for microbial contamination of the cell lines were negative. Chromosome analysis demonstrated that muscle cells possess a modal polyploid chromosome number of 264. The mitochondrial sequence data of COI genes and 12S rRNA confirmed that the developed cell line originated from A. dabryanus. Furthermore, transfection results indicate that muscle cells could be used for gene manipulation and functional studies. These results suggest that viable muscle cells could also be successfully isolated and cryopreserved from the wild Yangtze sturgeon in a short time after death. This report is not only of great significance for the germplasm rescue of critically endangered Yangtze sturgeon but also provides some scientific reference for the germplasm preservation of other endangered fish.

Energy consumption and the resulting climate change are the two major challenges to human sustainability. Hydrogen (H

This study commenced to uncover the role of long non-coding RNA FBXL19 antisense RNA 1 (FBXL19-AS1) in the development of ulcerative colitis (UC) and its possible mechanism.FBXL19-AS1 expression in the colonic sigmoid mucosa of UC patients was detected. A colitis model was induced in mice using 5% dextran sodium sulfate. Hematoxylin-eosin staining was performed for histopathological examination. Apoptosis was detected by Tunel staining and tissue fibrosis was detected by immunohistochemistry. Also, intestinal permeability was examined. The concentrations of inflammatory factors IL-1β and IL-18 were detected by enzyme-linked immunosorbent assay. The relationship between FBXL19-AS1, miR-339-3p and RHOB was verified by RNA immunoprecipitation assay and dual luciferase reporter assay.The expression of FBXL19-AS1 was increased in dextran sodium sulfate (DSS)-induced colitis mouse model. FBXL19-AS1 interference or miR-339-3p overexpression inhibited DSS-induced colonic epithelial cell apoptosis and inflammatory response, and improved intestinal epithelial barrier defects, thereby ameliorating DSS-induced colitis injury in mice. FBXL19-AS1 sponged miR-339-3p while miR-339-3p targeted RHOB. Overexpression of RHOB reversed the protective effect of inhibition of FBXL19-AS1 on DSS-induced colitis in mice.FBXL19-AS1 reduces miR-339-3p-mediated targeting of RHOB and aggravates intestinal epithelial barrier defect in DSS-induced colitis in mice.

To provide an overview of techniques for prevention, immediate diagnosis, and treatment strategies of intraoperative pulmonary embolism caused by renal tumor thrombus shedding.A total of 290 patients admitted into our medical center from March 2015 to May 2021 were retrospectively analyzed. All patients underwent radical nephrectomy with tumor thrombectomy. Six patients were diagnosed as pulmonary embolism during the perioperative period, of which two patients had tumor thrombus shedding. One patient underwent thoracotomy and thrombectomy, one patient underwent interventional thrombectomy, and four patients underwent conservative treatment. All patients have gone through our diagnosis and strategy flow chart. Demographic data, tumor characteristics, tumor thrombus characteristics, and follow-up data were collected.In the preoperative risk factor assessment, of the 253 patients who entered the follow-up, 163 were women, 48 were older than 60 years old, and 83 had a duration of more than 2 months. In addition, 27 patients had tumor thrombus with bland thrombus, and 43 patients had floating tumor thrombus. 78 patients underwent postoperative anticoagulation after evaluation. The average follow-up time was 23.3 For acute pulmonary embolism during nephrectomy and tumor thrombectomy, management strategies can be used to deal with intraoperative emergencies and provide reference.

Background: Trichinellosis is an important food-borne zoonosis, and no effective treatments are yet available. Nod-like receptor plays a critical role in the host response against nematodes. Therefore, we aimed to explore the role of the NLRP3 inflammasome (NLRP3) during the adult, migrating, and encysted stages of Trichinella spiralis (T. spiralis) infection. Methods: The mice were treated with the specific NLRP3 inhibitor MCC950 after inoculation with T. spiralis. Then, NLRP3 plays the role in T. spiralis-infected mice were evaluated using ELISA, Western blotting, Flow cytometry, Histopathological evaluation, Bone marrow-derived macrophage (BMDM) stimulation and immunofluorescenceResults: The in vivo results showed that NLRP3 enhanced the Th1 immune response in the adult stage and the migrating stage and weakened the Th2 immune response in the encysted stage. NLRP3 promoted the release of proinflammatory factors (INF-γ) and suppressed the release of anti-inflammatory factors (IL-4). Pathological changes were also improved in the absence of NLRP3 in mice during T. spiralis infection. Importantly, a significant reduction in adult worm burden and muscle larvae burden at 7 and 35 days post infection was observed in mice treated with the specific NLRP3 inhibitor MCC950. In vitro, we first demonstrated that NLRP3 in macrophages can be activated by T. spiralis proteins and promotes IL-1β and IL-18 release. Conclusions: This study revealed that the NLRP3 is involved in the host response to T. spiralis infection and that targeted inhibition of NLRP3 enhanced the Th2 response and accelerated T. spiralis expulsion. These findings may help in the development of protocols for controlling trichinellosis.

Interfacing with the human body, wearable and implantable bioelectronics are a compelling platform technology for healthcare monitoring and medical therapeutics. However, clinical adoption of these devices is largely shadowed by their weakness in humidity resistance, stretchability, durability, and biocompatibility. In this work, we report a self-powered waterproof biomechanical sensor with stretchability up to 440% using the giant magnetoelastic effect in a soft polymer system. By manipulating the magnetic dipole alignment, the sensor achieved a particularly broad sensing range from 3.5 Pa to 2000 kPa, with a response time of ∼3 ms. To validate the excellent performance of the magnetoelastic sensor in biomonitoring, both

Intestinal barrier dysfunction is inflammatory bowel disease's hallmark. Berberine (BBR) has manifested its anti-inflammatory properties in colitis. For exploring the molecular mechanism of BBR's impacts on colitis, application of a dextran sodium sulfate-induced mouse colitis

The conformal integration of electronic systems with irregular, soft objects is essential for many emerging technologies. We report the design of van der Waals thin films consisting of staggered two-dimensional nanosheets with bond-free van der Waals interfaces. The films feature sliding and rotation degrees of freedom among the staggered nanosheets to ensure mechanical stretchability and malleability, as well as a percolating network of nanochannels to endow permeability and breathability. With an excellent mechanical match to soft biological tissues, the freestanding films can naturally adapt to local surface topographies and seamlessly merge with living organisms with highly conformal interfaces, rendering living organisms with electronic functions, including leaf-gate and skin-gate transistors. On-skin transistors allow high-fidelity monitoring and local amplification of skin potentials and electrophysiological signals.

The high moisture level of exhaled gases unavoidably limits the sensitivity of breath analysis via wearable bioelectronics. Inspired by pulmonary lobe expansion/contraction observed during respiration, a respiration-driven triboelectric sensor (RTS) was devised for simultaneous respiratory biomechanical monitoring and exhaled acetone concentration analysis. A tin oxide-doped polyethyleneimine membrane was devised to play a dual role as both a triboelectric layer and an acetone sensing material. The prepared RTS exhibited excellent ability in measuring respiratory flow rate (2-8 L/min) and breath frequency (0.33-0.8 Hz). Furthermore, the RTS presented good performance in biochemical acetone sensing (2-10 ppm range at high moisture levels), which was validated via finite element analysis. This work has led to the development of a novel real-time active respiratory monitoring system and strengthened triboelectric-chemisorption coupling sensing mechanism.

Rechargeable aqueous zinc-ion batteries (AZIBs) that directly use metallic zinc as anode and mildly acidic Zn2+-containing aqueous solutions as electrolytes have exhibited promising complementarity for well-established lithium-ion batteries. The fabrication of high-voltage, high-capacity, and durable cathode and stable anode are the burning issues of fabricating high-performance AZIBs. Herein, the small amount of dual-cation preintercalated and amorphous carbon confined vanadium dioxide (Ni0.006Ca0.0045VO2@C) was prepared for high-performance Zn2+-storage materials, and subsequent in situ electrochemical anodic oxidation strategy was used to convert Ni0.006Ca0.0045VO2@C to δ-(Ni,Ca)V2O5@C as high-capacity AZIB cathode. The elaborate architecture not only showed a high specific capacity of 433.8 mAh g−1 at 0.1 A g−1 but also retained a reversible capacity of 74 mAh g−1 after 4000 cycles at 5 A g−1. In addition, the Zn2+/H+ co-intercalation mechanism was also verified by employing ex situ XRD and ex situ XPS. Finally, the flexible quasi-solid-state ZIBs were also assembled with the Ni0.006Ca0.0045VO2@C as cathode and polyvinyl alcohol hydrogel as electrolyte, suggesting its promising application for the superior Zn2+-storage performance.

In this work, we have propose a simple and facile hydrothermal method for the synthesis of 2D porous CeO2@Co3O4 sheet-like heterostructures with superior supercapacitor performance.

A new sodium vanadyl fluorophosphate (Na(VO)2(PO4)1.5F0.5) as a high-rate and stable cathode is prepared by a simple solvothermal method, which delivers superior aqueous energy storage performance based on the Na+/Zn2+ co-insertion mechanism.

Study of mechanical properties of rock under hydro-mechanical coupling. The MTS815 rock mechanics system is used to perform triaxial compression tests of water-saturated sandstones under different confining pressures and pore water pressures. The results show that the peak deviation stress and its corresponding axial strain, residual deviation stress, initial deviation stress of dilation and deformation modulus of water-saturated sandstone are related to pore water pressure and confining pressure. They decrease with the increase of pore water pressure and increase with the increase of confining pressure. Poisson’s ratio and angle of rupture of water-saturated sandstone increase with pore water pressure. Based on the effective stress principle and Mohr–Coulomb criterion, the effective cohesion and effective residual cohesion of sandstone are 11.49 and 3.13 MPa, respectively, and the effective angle of internal friction and effective residual angle of internal friction are 38.32° and 25.32°, respectively. In addition, according to the variation relationship of sandstone strength, the relative strength criterion of sandstone under hydro-mechanical coupling is established.

Traditional public health systems are suffering from limited, delayed, and inefficient medical services, especially when confronted with the pandemic and the aging population. Fusing traditional textiles with diagnostic, therapeutic, and protective medical devices can unlock electronic textiles (e-textiles) as point-of-care platform technologies on the human body, continuously monitoring vital signs and implementing round-the-clock treatment protocols in close proximity to the patient. This review comprehensively summarizes the research advances on e-textiles for wearable point-of-care systems. We start with a brief introduction to emphasize the significance of e-textiles in the current healthcare system. Then, we describe textile sensors for diagnosis, textile therapeutic devices for medical treatment, and textile protective devices for prevention, by highlighting their working mechanisms, representative materials, and clinical application scenarios. Afterward, we detail e-textiles' connection technologies as the gateway for real-time data transmission and processing in the context of 5G technologies and Internet of Things. Finally, we provide new insights into the remaining challenges and future directions in the field of e-textiles. Fueled by advances in chemistry and materials science, textile-based diagnostic devices, therapeutic devices, protective medical devices, and communication units are expected to interact synergistically to construct intelligent, wearable point-of-care textile platforms, ultimately illuminating the future of healthcare system in the Internet of Things era.

The design and preparation of electrode materials are of great significance for improving the overall performance of energy storage devices. Zeolitic imidazolate frameworks (ZIFs) and their derivatives have attracted significant attention as they provide a library of new energy storage materials. ZIFs act as the perfect precursor due to their high porosity, controllable crystal structures, and tunable chemical compositions. The high structural tunability endows ZIFs and ZIFs-derivatives with broad application prospects in various energy storage devices. In this review, we discussed the crystal structures and preparation methods of ZIFs and focused on the application progress of ZIFs and ZIFs-derivatives in supercapacitors and batteries. Furthermore, we summarized the current challenges and provided perspectives about ZIFs and their derivatives for future electrode materials, aiming to fully understand this field and promote the widespread use of ZIF-based composites and ZIF-derived materials in the field of energy storage.

This article proposes a cascade proportional-integral second-order sliding mode control (PI-SMC) method for matrix converter-fed brushless doubly fed induction machine (BDFIM). The PI-SMC method consists of a PI speed controller with an inner-loop second-order sliding mode control (SMC). The PI controller provides a reference to the inner-loop second-order SMC with constraints according to the system requirements in terms of maximum current and speed. As the discontinuous sign function in the traditional SMC is replaced by the continuous supertwisting function, the chattering problem is eliminated for inner-loop second-order SMC. Moreover, the inner-loop second-order SMC has robustness and interference immunity against nonlinear disturbances of the BDFIM. Simulation and experimental results demonstrate the excellent robust tracking performance of the proposed PI-SMC method.

To date, researchers have found that poor mental health was common during the COVID-19 epidemic. Even if they had been relatively resistant to suicidal ideation during the first three waves of the pandemic, university students may experience a delayed impact on their mental health.The study intended to measure mental health among university students in Wuhu City, China and to identify an effective approach to universities can use to prevent mental-health issues.The research team performed a cross-sectional study.The study took place at Anhui polytechnic university, Wuhu, China.Participants were 2371 students at Anhui polytechnic university in Wuhu city, China.The research team used the two-item General Health Questionnaire-12 (GHQ-12) to measure participants' mental health.Among the 2371 participants, 1727 had poor mental health (72.84%), including 843 males (48.81%) and 884 females (51.19%). Poor mental health was significantly associated with an urban residential location (P.01), the female gender (p0.01), the second school year (P.01), and the parents' education level of junior high school or below (both P.01).The current study suggests that poor mental health among university students is common. Being female, from an urban area, and in the second year of school and having parents with an education of junior high school or below had poorer mental health than those who were male, from the countryside, and in the first year of school and who had parents with a higher level of education.

Gearbox vibration signals are usually disturbed under strong noise. Therefore, the fault feature frequency cannot be extracted accurately and effectively. In order to extract the fault feature of the gearbox, a method based on compound time-frequency atomic dictionary and orthogonal matching pursuit (OMP) optimized by wingsuit flying search algorithm (WFSA) is proposed. Firstly, according to the feature of the gearbox fault vibration signal, a compound time-frequency atomic dictionary composed of steady state modulation dictionary and impact modulation dictionary is designed. In addition, in order to improve the accuracy and efficiency of signal sparse decomposition. In this paper, WFSA is used to optimize the dictionary atomic parameters in OMP, so that the dictionary atom approximated the original signal better. Through simulation analysis and experimental verification and compared with the commonly used gearbox fault feature extraction methods, the superiority and effectiveness of the method are verified.

Unique two-dimensional (2D) porous nanosheets with overwhelmingly rich channels and large specific surface area exhibit superior electrochemical capacitance performance, as compared to the conventional zero- and one-dimensional counterparts. As ternary transition metal sulfides (TMSs) are well recognized for their high electrochemical activity and capacity, and the replacement of oxygen with sulfur may result in high stability and flexible properties of the nanomaterials, as compared to transition metal oxides, herein we report the synthesis of 2D porous nanosheet arrays of ZnxCo1-xS (x = 0, 0.25, 0.5, 0.75, and 1) via a facile hydrothermal process. Due to the synergistic effect of the metal components and a unique 2D porous structure, the Zn0.5Co0.5S electrode was found to stand out as the best among the series, with a high specific capacity of 614 C g−1 at 1 A g−1 and excellent cycle retention rate of 90 % over 10, 000 cycles at 10 A g−1. Notably, a supercapattery based on a Zn0.5Co0.5S positive electrode and an activated carbon (AC) negative electrode (Zn0.5Co0.5S//AC) was found to display a 1.6 V voltage window, a 61 mA h g−1 specific capacity at 1 A g−1, a 49 Wh kg–1 energy density at 957 W kg–1 power density, and excellent cycling performance (88 % over 10, 000 cycles), suggesting tremendous potential of Zn0.5Co0.5S in the development of high-performance supercapattery devices.

Metal phosphates, such as LiFePO4 (LFP), have been attracting extensive attention as electrode materials for next-generation rechargeable metal-ion batteries (MIBs), due to their high theoretical capacity, good chemical stability, long lifespan, and natural abundance. In this review, the recent progress of the design and engineering of metal phosphate-based electrode materials for MIBs is summarized. Specifically, the survey will focus on three types of phosphates, monometallic phosphates, bimetallic phosphates, and multi-metal phosphates, within the context of their intrinsic structure and corresponding electrochemical performance. A range of experimental variables will be carefully analyzed, such as sample synthesis, crystal structure, and electrochemical reaction mechanism, in conjunction with theoretical calculations. The applications of these materials as MIB electrodes are then featured for diverse MIBs, such as lithium-ion battery, sodium-ion batteries, potassium-ion batteries, calcium-ion batteries, and magnesium-ion batteries. We conclude the review with a perspective where the promises and challenges of phosphate-based electrodes for MIBs are highlighted, along with future research directions.

Two-dimensional (2D) heterostructures have attracted a great deal of attention in electrochemical energy storage (EES) due to their unique structure and superior performance. Here, we demonstrate a simple and facile hydrothermal method to prepare 2D porous CeO

The toxic renal accumulation of bile pigment sparked clinical intrigue almost a century ago. More recently, however, the identification of bile casts within renal tubules in patients with liver dysfunction has been largely overlooked. We have reviewed the literature, including natural history, pathophysiology, and potential treatment of bile cast nephropathy (BCN). We report two cases of acute kidney injury (AKI) associated with acute-on-chronic liver failure in which prolonged hyperbilirubinemia and bile cast identification on renal biopsy evoked the diagnosis of BCN.

Background Circular RNAs (circRNAs) are crucial in the regulation of gene expression and biological processes. However, in colorectal cancer, the expression characteristics and biological function of circRNA_0006174 (circ_0006174) is not fully understood. This work is aimed to investigate the biological function of circ_0006174 in colorectal cancer and its molecular mechanism. Methods Circ_0006174, microRNA-142-3p and X-linked inhibitor of apoptosis expression levels were detected in colorectal cancer tissues and cells using quantitative real-time polymerase chain reaction analysis or Western blot. The effects of circ_0006174 on colorectal cancer cell proliferation, apoptosis, migration and invasion were detected using the cell counting kit-8 method, bromodeoxyuridine experiments, flow cytometry analysis and Transwell experiments. The targeting relationship among circ_0006174, microRNA-142-3p and X-linked inhibitor of apoptosis was analysed by bioinformatics prediction, dual-luciferase reporter experiment and RNA immunoprecipitation experiment. Results Circ_0006174 was up-regulated in colorectal cancer tissues as well as in cell lines, and its high expression was remarkably associated with enlarged tumour volume and advanced tumour, node, metastasis stage of the patients. Circ_0006174 overexpression enhanced colorectal cancer cell proliferation, migration and invasion, and inhibited colorectal cancer cell apoptosis; while knocking down circ_0006174 caused the opposite effects. Circ_0006174 directly targeted and negatively regulated microRNA-142-3p expression, and X-linked inhibitor of apoptosis, a target gene of microRNA-142-3p, could be indirectly and positively modulated by circ_0006174. Conclusion Circ_0006174 facilitates colorectal cancer cell proliferation, migration and invasion, and represses colorectal cancer cell apoptosis by regulating microRNA-142-3p/X-linked inhibitor of apoptosis axis.

AIM To detect the mechanisms of Helicobacter pylori (H. pylori) infection in the invasion and metastasis of gastric cancer (GC). METHODS Specimens from 99 patients with GC were collected. The correlation among H. pylori infection, heparanase (HPA) and mitogen-activated protein kinase (MAPK) expression, which was determined by immunohistochemistry, and the clinical features of GC was analysed using SPSS 22.0. Overall survival (OS) and relapse-free survival (RFS) of GC patients were estimated by the Kaplan-Meier method. Independent and multiple factors of HPA and MAPK with prognosis were determined with COX proportional hazards models. HPA and MAPK expression in MKN-45 cells infected with H. pylori was analysed using Western blot. RESULTS H. pylori infection was observed in 70 of 99 patients with GC (70.7%), which was significantly higher than that in healthy controls. H. pylori infection was related to lymph metastasis and expression of HPA and MAPK (P < 0.05); HPA expression was relevant to MAPK expression (P = 0.024). HPA and MAPK expression in MKN-45 cells was significantly upregulated following H. pylori infection and peaked at 24 h and 60 min, before decreasing (P < 0.05). SB203580, an inhibitor of MAPK, significantly decreased HPA expression. HPA was related to lymph metastasis and invasive depth. HPA positive GC cases and H. pylori positive GC cases showed poorer prognosis than HPA negative cases (P < 0.05). COX models showed that the prognosis of GC was connected with HPA expression, lymph metastasis, tissue differentiation, and invasive depth. CONCLUSION H. pylori may promote the invasion and metastasis of GC by increasing HPA expression that may associate with MAPK activation, thus causing a poorer prognosis of GC.

Typical layered structures with large capacity have attracted much interest in lithium ion batteries and emerging post-lithium ion batteries. However, these typical layered oxides, including α-, δ-V2O5, δ-MnO2, and α-MoO3, have suffered poor electrical conductivity, severe structural deterioration, and sluggish diffusion kinetics during the repetitive charging/discharging process. In recent years, interlayer engineering of preintercalation strategies has offered effective solutions for solving these problems. Structural water molecules (H2O), monovalent alkali cations (Li+/Na+/K+) and ammonium ion ( NH 4 + ), multivalent alkali-earth cations (Mg2+/Ca2+/Ba2+) and aluminum ion (Al3+), various transition metal cations (Mn2+/Fe2+/Co2+/Ni2+/Cu2+/Zn2+/Ag+, etc.), and organic molecules (PANI/PEDOT/PEO, etc.) have been proved to be efficient “pillars” for stabilizing the fragile layered structure and enhanced diffusion kinetics. These prominent effects have boosted the developments of preintercalated layered structures for emerging multivalent metal-ion batteries, especially rechargeable aqueous zinc ion batteries (AZIBs). In this review, we have clarified the representative crystal structures, preparation methods, advanced characterization methods and corresponding mechanistic insights, and successful applications of these preintercalated layered oxides in multivalent metal-ion batteries.