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1. Cytokine profiling: variation in immune modulation with preterm birth vs. uncomplicated term birth identifies pivotal signals in pathogenesis of preterm birth

Author

Denney, Jeffrey M, Nelson, Edward, Wadhwa, Pathick, Waters, Thaddeus, Mathew, Leny, Goldenberg, Robert L, and Culhane, Jennifer F

Subjects
Adult, Monitoring, Term Birth, Clinical Sciences, Gestational Age, Reproductive health and childbirth, Low Birth Weight and Health of the Newborn, Paediatrics and Reproductive Medicine, Immunologic, Risk Factors, Pregnancy, Preterm, Infant Mortality, Humans, Prospective Studies, Obstetrics & Reproductive Medicine, Pediatric, immune profiling, Smoking, Pregnancy Outcome, Immunity, Low Birth Weight, Infant, preterm birth, Perinatal Period - Conditions Originating in Perinatal Period, Newborn, United States, cytokines, inflammation, Premature Birth, Female, Pregnancy Trimesters
Abstract

ObjectivesTo assess deviations in longitudinally measured cytokines with preterm birth (PTB).MethodsProspective longitudinal study targeting 80 subjects. Phlebotomy specimens for broad panel of cytokine analysis were obtained at three time (T)intervals: first trimester (T1: 8-14weeks' gestation), second trimester (T2: 18-22weeks' gestation), and third trimester (T3: 28-32weeks' gestation). Important demographics and outcomes were tracked. Data were stratified and the target groups were analyzed as follows: "Uncomplicated" (delivered≥37weeks) or "Preterm Birth" (

Published
2021

2. Additional file 1: Table S1. of A retrospective cohort study of factors relating to the longitudinal change in birth weight

Author

Gibson, Kelly, Waters, Thaddeus, Gunzler, Douglas, and Catalano, Patrick

Abstract

Univariate Pearson correlation coefficients between independent variables and birth weight, birth length, and ponderal index. Table S2. Univariate Pearson correlation coefficients between independent variables to assess for multicollinearity. Table S3A. Estimated Change in Newborn Birth Weight by Relevant Maternal and Newborn Factors by Race for African Americans. Table S3B. Estimated Change in Newborn Birth Weight by Relevant Maternal and Newborn Factors by Race for non-African Americans. (DOC 64 kb)

Published
2015
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