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Purpose This study aims to investigate survival outcomes and prognostic factors for upward nasopharyngeal carcinoma (NPC) patients receiving radiation therapy (RT) combined with chemotherapy (CT). Methods A total of 421 previously untreated, newly diagnosed T4N0-1 NPC patients, who were identified within the Surveillance, Epidemiology, and End Results (SEER) registry (years 2004–2015), were collected and retrospectively reviewed. All patients received treatment of RT and CT. Kaplan-Meier analysis was used to evaluate overall survival (OS) and cancer-specific survival (CSS). The differences in OS and CSS were compared using Log-rank test. The independent prognostic factors were established by using univariate and multivariate Cox proportional hazard models. Results With a median follow-up duration of 37 months (range: 3-154 months), the 5-year estimate OS and CSS rates were 59.3% and 63.7%, respectively. N0 and ≥ 65 years were poor prognostic factors for OS and CSS. Moreover, histology and race were associated with OS and CSS. Univariate analysis indicated that ≥ 65 years, N0, NHB and grade III were unfavorable independent prognosticators of OS and CSS. Multivariate analysis demonstrated that ≥ 65 years, N0 and NHB were correlated with poor OS and CSS. Conclusion Patients with stage T4N0-1 NPC receiving RT plus CT had favorable OS and CSS. Moreover, age, N stage and race were independent prognostic factors of OS and CSS.

With the rapid development of the auto industry, our environment confronts more pressure. Fuzzy adaptive control by seeking the three parameters of PID controller and the relationship between the idle error e and the error change rate ec, make the best adjustment for PID parameters on the gasoline idle speed control, and to keep gasoline well property under the low rotation. The simulation result shows that the fuzzy adaptive PID controller can better meet properties requires of idling control, at the same time, the system has strong anti-disturb capability.

In the forward link of many WCDMA proposals for IMT-2000, pilot symbol aided coherent demodulation (PSACD) is employed. The more pilot symbols there are, the more accurate the channel estimation is, but this will cause more information loss. This paper analyzes this trade-off by deriving the analytical error performance and performance loss due to pilot symbol aided coherent demodulation. Thus we can optimize the space between two neighbor pilot symbols.

A new type of interference cancellation multiuser receiver combining the pilot-aided coherent demodulation method is proposed and analyzed here. According to our theoretical analysis and numeric results, it can be concluded that this new method can improve the system performance greatly with less cost of hardware complexity and process time delay.