Search

To characterize the behavior of three different polymeric agents before and after an erosive challenge on dentin permeability, to analyze their degradation in both conditions, and to analyze their degree of conversion (DC).The permeability of human dentin disks (1.0 ± 0.2 mm) was measured with smear layer, after its removal, after treatment (LpTreat) with Gluma Desensitizer, PRG Barrier Coat (PBC) or Icon infiltrant (n = 11/group) and after exposure to citric acid (LpEro) (6%, pH 2.1, 1 min). The specimens were analyzed under a Laser Scanning Confocal Microscope (n = 2/group) and the products' DC were calculated. Data were subjected to 2-way repeated measures ANOVA and post-hoc Bonferroni (permeability analysis), to paired t-test (for specimens treated with Icon) and to t-test (DC analysis) (α 0.05).Icon showed the lowest LpTreat and LpEro values, while PBC and Gluma did not differ from each other under these conditions. Icon and PBC showed LpEro similar to a dentin with smear layer. Under the Laser Scanning Confocal Microscope, more deposits were noticeable on dentin after treating with PBC. Gluma presented the deepest penetration in dentin. The DC of PBC was the highest.Icon caused the highest reduction on permeability values, followed by PBC and Gluma. PBC generated more deposits covering dentin and seemed to be more efficient after an erosive challenge. The association of a polymeric resin with inorganic ion-releasing fillers seem to be a great strategy to manage dentin hypersensitivity under erosive conditions.

Teeth affected by molar incisor hypomineralization (MIH) present micromorphologic changes and hypersensitivity, which increase the risk of developing caries lesions and affect bonding procedures. Considering that practitioners still misdiagnose teeth affected by MIH, there is an urge for more knowledge about this topic in order to propose a more adequate and conservative treatment. The purpose of this study was to report the clinical challenges regarding the restorative management of a patient with MIH. A 13-year-old girl sought dental treatment, complaining about hypersensitivity in posterior teeth. Under clinical exams, notable enamel alterations mainly affecting posterior teeth (including molars) presented particular characteristics frequently attributed to MIH, and visible stains on maxillary central incisors were present. Because the mineral and organic content of MIH-affected enamel differ from sound enamel, it may imply special care for bonding of a restorative material. Thus, in order to promote a minimally invasive approach, selective removal of carious tissue and restoration with microhybrid composite resin was conducted after application of a universal bonding system used as self-etching strategy. After a 2-year follow-up, the restorations presented good clinical performance and the patient had limited hypersensitivity discomfort, suggesting a promising performance.

Particularities of dental cervical lesions require distinct approaches from preventive to therapeutic managements. Therefore, practitioners depend on their etiology, selected materials and patient involvement to provide conditions to effective performance. Through representative clinical scenarios, the main considerations regarding carious and non-carious cervical lesions (NCCL) are reported for the determination of strategies. Details regarding the disease, lesions aspects, evolution and involvement or not of the periodontal tissues are considered in their decision. In conclusion, their long-lasting resolution is determined by a complex combination of biomechanical factors and therapeutic strategies for each particular lesion, regardless of the cervical location solely.

Objectives Most dental schools have included dentin hypersensitivity (DH) as part of their taught curriculum to educate undergraduates; however, it is possible that the public still does not recognize its symptoms and the factors that predispose to the onset of this condition. Thus, the aim of this study was to assess the knowledge of a Brazilian population regarding the prevention and treatment of DH and to identify what self-reported factors can serve as predictors of the frequency of DH. Materials and Methods An online questionnaire investigated the demographic characteristics, oral health self-perception and attitudes, and DH prevention and treatment measures of 226 participants. Statistical analysis Data were analyzed descriptively and by a multiple linear regression with DH frequency score as the dependent variable (α Results Total 61.1% of females (n = 138) and 38.9% of males (n = 88) (mean age: 35.1 ± 12.2 years) completed the questionnaire. The sample's mean DH frequency score (minimum 0; maximum 20) was 4.2 and classified as low, with 19.1% using desensitizing products and 22.1% reporting having noncarious cervical lesions (NCCLs). When experiencing DH episodes, 21.2% never and 30.1% rarely scheduled dental appointments. Regression analysis retrieved a significant final model (F [5,220] = 12.047; p Conclusion This study identified that 36.7% and 18.6% of the sample were unaware that DH can be both prevented and treated, respectively. Moreover, the presence of NCCLs, frequency of daily toothbrushing, use of desensitizing products, presence of DH modulating factors, and the presence of parafunctional habits symptoms served as predictors of DH frequency.

This case report described the use of a stamping technique associated with a bulk fill composite to restore an ICDAS 4 carious lesion on a posterior tooth. The 4-year follow-up is also presented.A 32-year-old patient presented a carious lesion on tooth 36 with an underlying dark shadow at the dentin seen from the noncavitated enamel occlusal surface, which was compatible with an ICDAS 4 carious lesion. The lesion was radiographically detected and the caries disease was treated with dietary and hygiene habits orientations. Before accessing the lesion and selectively removing the carious tissue, an occlusal stamp was made by applying a flowable resin composite to copy the anatomy of the noncavitated enamel surface. The cavity was restored using a bulk fill resin composite (Opus Bulk Fill, FGM) with 4-mm-thick increments. Before curing the last increment, a Teflon band was adapted at the uncured bulk fill composite surface and the occlusal stamp made with the flowable composite was pressed against it to reproduce the natural characteristics and initial occlusal anatomy. The top surface was light-activated for 40 s. After 4 years, small wear could be seen in the restoration, but still within clinically acceptable levels.The occlusal stamp technique allows reproduction of the natural anatomy of teeth affected by ICDAS 4 carious lesions with good clinical longevity over 4 years.This case report presents the use of the stamp technique to restore a tooth affected by an ICDAS 4 lesion, in which a carious process reached the dentin and the enamel anatomy was still preserved. The bulk fill resin composite associated with the occlusal stamp was chosen to quickly restore the cavity with clinical predictability. Bulk fill composites allow the insertion of up to 4-mm-thick increments and offer lower shrinkage stress, good clinical longevity and a less time-consuming procedure in cases of posterior teeth, especially if associated with the stamp technique.

Objectives: Resin composites containing surface pre-reacted glass (S-PRG) were introduced to reduce demineralization and improve remineralization of the tooth structure. However, water diffusion within the material is necessary for its action, which can impair its overall physical-mechanical properties over time, including the color stability. This study aimed to evaluate the color stability and related degree of conversion (DC) of four resin composites.Materials and Methods: Discs (n=5/group) of microhybrid, nanofilled, nanohybrid, and S-PRG-based nanohybrid composites with two opacities were prepared. Color (CIELab and CIEDE2000) was evaluated after aging in grape juice. The DC was analyzed by using Fourier Transform Infrared Spectroscopy before and after photopolymerization. Data were statistically analyzed by using two-way analysis of variance and post-hoc least significant difference tests (PResults: In the color stabilityanalysis, the interaction between filler type and opacity was significant. S-PRG influenced color stability and DC.Conclusions: The nanohybrid resin composite presented favorable color stability and a greater DC, which is likely related to its organic content. S-PRG based nanohybrid resins require caution since its bioactive benefits depends on interaction with the environment that can be prone to impair color stability.Clinical Relevance: As color stability is mandatoryin specific regions, staining can jeopardize the esthetics of a resin composite. The use of nanohybrid composites with no or reduced BisGMA content and diluents may be more appropriate in these areas. Since materials containing S-PRG can offer relevant benefits, professionals need to balance their higher susceptibility to staining favoring other relevant properties.

Obesity and pregnancy may have synergistic effects on maternal periodontal tissues. In contrast, maternal obesity and periodontitis are antagonistic factors for the babies' weight at birth. This study evaluated, during pregnancy (T1) and after delivery (T2), periodontal parameters and salivary levels of cytokines in women with obesity, and the association of these outcomes with the baby's weight at birth.After matching by age, socioeconomic status and systemic health, the sample was composed of pregnant women with obesity (GO = 25; BMI ≥30 kg/mGO showed higher prevalence of periodontitis in T1 and T2 (p 0.001), with higher salivary levels of TNF-α (p = 0.003) and IL-1β (p = 0.009) in T1. IL-1β significantly decreased after delivery in GO. No intergroup differences for leptin levels were found, but both groups had a significant reduction of leptin levels between periods (p 0.001). GO had children with lower birth weight (p = 0.022), being classified as low (2,500 g) or insufficient (2,500-2,999 g) weight.It is suggestive that the inflammatory pattern caused by obesity and periodontitis, mainly related to high levels of TNF-α, impair the babies' weight at birth, resulting in more frequency of low/insufficient weight at birth.

This study evaluated the protective effect of TiF

To evaluate the penetration depth (μm) of experimental resin infiltrants containing different percentages of triethylene glycol dimethacrylate (TEGDMA) and phosphoric acid 2-hydroxyethyl methacrylate ester (PAM) in artificial carious white spot lesions (WSL).WSL were produced in 65 bovine flat enamel specimens by pH cycling protocol, which were treated with either Icon (control) or experimental acidic infiltrants based on different percentages of TEGDMA and PAM monomers (acidic), and their association or not with previous acid-etching with phosphoric acid. Ten readings using Confocal Laser Scanning Microscopy were conducted on each specimen and the penetration depth was calculated from the surface until the deepest point with the fluorescent dye Rhodamine B (0.02 mg/mL). The pH and the viscosity of the experimental infiltrants were also tested. Data were statistically analyzed with two-way ANOVA and Tukey tests (α 0.05).The material factor and the interaction material*acid-etching were statistically significant. The lowest penetration depth was observed for the samples treated with the commercial infiltrant after etching with 15% hydrochloric acid. When specimens were pre-treated with PA, highest penetration was seen for specimens treated with 100% TEGDMA, which differed from all other groups. The lowest penetration was seen for those treated with 50:50 TEGDMA:PAM infiltrants. When specimens were not previously etched, highest penetration was seen for Icon, which differed only from those treated with 25% TEGDMA 75% PAM, where the lowest values were seen. The values of viscosity increased and the pH decreased with the addition of PAM in the infiltrant formulations.the association between TEGDMA and PAM seems to allow similar infiltration depth reached by Icon infiltrant without acid etching the enamel surface.

Statement of problem Tooth loss directly affects mastication, cognitive function, and oral health-related quality of life (OHRQoL). Complete dentures (CDs) and removable partial dentures (RPDs) represent a common oral rehabilitation approach. However, studies addressing the impact of removable dentures on replacing missing teeth are lacking. Purpose The purpose of this clinical study was to evaluate whether the OHRQoL, the jaw function limitation (JFL), and the masticatory efficiency of CD and RPD wearers are similar to those of patients with natural teeth and to evaluate whether wearing removable dentures can predict an effect on the OHRQoL, JFL, and masticatory efficiency of their wearers. Material and methods The Oral Health Impact Profile (OHIP-14) questionnaire and the JFL scale were used to measure OHRQoL and JFL. Masticatory efficiency was analyzed by using a subjective color-mixing index for the chewing gum bolus and shape index and an objective colorimetric analysis by using a software program ViewGum. Data were analyzed with Kruskal-Wallis and post hoc Dunn tests, followed by multiple linear regression (α=.05). Results The results from OHIP-14 evidenced that both denture groups presented a low impact on OHRQoL. JFL was higher for all denture wearers. For the subjective color-mixing analysis, the control and RPD groups presented better masticatory efficiency than CD wearers. Colorimetric analysis evidenced better masticatory efficiency for the control group, who differed from the CD and RPD groups. Wearing RPDs was a predictor of impaired JFL and OHRQoL, and the use of CDs was a predictor of impaired JFL and masticatory efficiency. Conclusions Despite being rehabilitated, CD and RPD wearers still had impaired OHRQoL, JFL, and masticatory efficiency. Also, the use of these prostheses can predict a negative effect on these 3 variables.

Made available in DSpace on 2020-12-12T01:19:33Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-06-01 Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) This study aimed to produce a new SiO2+Y-TZP ceramic via uniaxial/isostatic compression that was structurally and chemically characterized relating to its translucency and flexural strength. SiO2 and Y-TZP were mixed using a ball mill, pressed and sintered at 1150 °C. The optical and mechanical properties of the specimens were compared to lithium disilicate (LD) and zirconia-reinforced lithium silicate (ZLS) (Kruskal-Wallis, α = 0.05). The Fourier Transform Infrared Spectroscopy bands suggested an interaction between Si, O and Zr. Contrast ratio and translucency parameter of the experimental ceramic were higher and lower, (p = 0.000001) respectively, than those of the LD and ZLS. The experimental ceramic presented similar flexural strength to ZLS, but lower than LD (p < 0.0001). It can be concluded that this processing method is efficient to obtain a SiO2+Y-TZP ceramic and 1150 °C crystallizes SiO2 without inducing t-m transformation. The SiO2+Y-TZP ceramic presented lower translucency and higher masking ability than the commercially available glass-ceramics, but similar flexural strength to one glass-ceramics. Department of Operative Dentistry Endodontics and Dental Materials Bauru School of Dentistry University of São Paulo Department of Prosthodontics and Periodontics Bauru School of Dentistry University of São Paulo Department of Chemistry UNESP-School of Science São Paulo State University Department of Mechanical Engineering São Carlos School of Engineering University of São Paulo Department of Physics UNESP-School of Science São Paulo State University Department of Biomaterials and Oral Biology School of Dentistry University of São Paulo Department of Pediatric Dentistry Orthodontics and Public Health Bauru School of Dentistry University of São Paulo Department of Chemistry UNESP-School of Science São Paulo State University Department of Physics UNESP-School of Science São Paulo State University FAPESP: 2017/18157-4

This study aimed to produce a new SiO

Objectives This study evaluated the erosive tooth wear promoted by commercial whitening toothpastes on eroded dentin in vitro. Design Ninety bovine roots were embedded, polished and subjected to the baseline profile analysis. The samples were protected in 2/3 of the dentin surface and were randomly assigned to 6 groups (n = 15/group): Oral-B 3D White; Close-up Diamond Attraction Power White; Sorriso Xtreme White 4D; Colgate Luminous White; Crest and erosion only. All samples were submitted to erosive pH cycles (4 × 90 s in 0.1% citric acid, pH 2.5, per day) and abrasive challenges (2 × 15 s, per day) for 7 days. The samples were subjected to abrasion, using toothbrushing machine, soft toothbrushes and slurries of the tested toothpastes (1.5 N, 1:3 water). Between the challenges, the samples were immersed in artificial saliva. The final profile was overlaid to the baseline profile for the calculation of the erosive dentin wear (μm). The data were subjected to Kruskal-Wallis/Dunn tests (p Results Colgate Luminous White (4.7 μm) and Sorriso Xtreme White 4D (4.0 μm) promoted the highest wear, similarly to Oral-B 3D White (2.3 μm). Oral-B 3D White promoted similar wear compared to Crest (1.1 μm) and Close-up Diamond Attraction Power White (1.2 μm); however, it induced significant higher dentin wear compared to erosion only (1.0 μm). Close-up Diamond Attraction Power White and Crest did not increase the erosive wear compared to erosion only. Conclusion Some whitening toothpastes increase the wear of eroded dentin, which should be considered by the dentist when prescribing them to patient with root exposure.

Statement of problem Although the 2D analysis of prosthesis cementation space has been popular, its correlation with volumetric comparison (3D data) of cement space is unclear. Purpose The purpose of this in vitro study was to evaluate the cement space in computer-aided design and computer-aided manufacturing (CAD-CAM) crowns of different materials and correlate 2D measurements of cement space with their corresponding 3D values (volume of cement space) by using microcomputed tomography (μCT) analysis of regions of interest. Material and methods Ten molar crowns were milled in lithium disilicate (LD), resin nanoceramic (RN), and zirconia (Z) ceramics. Silicone replicas were produced and used as the analog cement layer and scanned with a desktop X-ray microfocus CT scanner. Twenty-eight slices were evaluated in 3 regions: marginal, axial, and occlusal (n=84 measurement points/specimen). After 3D reconstruction of the cement space, the volume was calculated. Data were statistically evaluated through 2-way ANOVA and Bonferroni test (α=.05). The Pearson correlation test was used to investigate the correlation between the 2D and 3D data. Results The volumes of the occlusal (LD 10 ±1 mm3; RN 9 ±1 mm3) and axial regions (LD 9 ±2 mm3; RN 8 ±1 mm3) were significantly higher than the volume of the marginal region for LD and RN specimens (LD 6 ±2 mm3; RN 4 ±1 mm3) (both P Conclusions Z showed more volume of cement space, as well as thicker cement space than LD and RN. The μCT analysis is an efficient method of analyzing cement thickness and volume in ceramic crowns at the selected regions of interest. A moderate positive correlation was found between the 2D and 3D analyses for the axial and marginal regions of ceramic crowns.

Objectives This study evaluated the staining potential of TiF4 varnish and TiF4/NaF solution on both sound and previously eroded enamel in vitro. Methods One hundred and eighty bovine enamel samples were polished; half of them remained sound and the other half was eroded (4 × 90 s each, using a 0.1% citric acid). Thereafter, the baseline color reading was performed (T0). The samples were then subdivided into the following treatments: TiF4 varnish (24,500 ppm F, 1 × 6 h), NaF varnish (24,500 ppm F, 1 × 6 h), placebo varnish (1 × 6 h), TiF4/NaF solution (500 ppm F, 6 × 1 min), Erosion Protection-Elmex® (500 ppm F, 6 × 1 min) and control (water, 6 × 1 min). Between the applications, the samples were exposed to artificial saliva for 30 min. The color changes were measured immediately after the applications (T1-T6) and after the exposure to artificial saliva (S1-S6) by using a spectrophotometer (Vita EasyShade®). The ΔE00, L*, a* and b* data were compared using 2-way ANOVA/Tukey (p Results TiF4 varnish induced significantly higher color change (ΔE00) compared to NaF and placebo varnishes on sound enamel immediately after application, but not after saliva exposure. TiF4/NaF solution induced lower ΔE00 values compared to control on sound enamel; however, no differences were found between TiF4/NaF and Elmex®. For eroded, no differences were seen between the tested varnishes and solutions. Both types of fluoride solutions increased the yellow appearance of enamel, while the varnishes did not. Conclusions The color changes induced by the experimental TiF4 products are similar to the commercial ones. Clinical significance Both TiF4 varnish and TiF4/NaF solution have shown staining potential similar to commercially available varnish (NaF) and solution (Elmex®) on sound and eroded enamel. These findings support the conduction of clinical trials, which, in the future, may lead to the commercialization of these products.

Made available in DSpace on 2022-04-28T19:27:23Z (GMT). No. of bitstreams: 0 Previous issue date: 2019-01-01 Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) Aim: This study aimed to evaluate oral and systemic conditions in morbidly obese patients with and without metabolic syndrome (MS) prior to bariatric surgery. Methods: One hundred patients were included and equally divided into two groups: G1 - with MS (n = 50) and G2 - without MS (n = 50). MS was diagnosed in patients presenting at least three of five signs: abdominal obesity, high triglyceride level, low high-density lipoprotein cholesterol (HDL-C) level, hypertension, and altered fasting glycemia. Variables analyzed included the patients' age, sex, body mass index (BMI), waist-to-hip ratio (WHR), and number of missing teeth. Both BMI and WHR were used to evaluate the risk of developing cardiovascular disease (RCVD). Mann-Whitney, Chi-squared, t test, hierarchical multiple linear regression and binary logistic regression models were used in statistical analyses (p < 0.05). Results: There were no group-wise differences in sex (p=0.631) and BMI (p=0.200); however, the WHR (p=0.009), age (p=0.0001), and number of missing teeth (p=0.0003) were higher in G1. Obese patients with MS who were candidates for bariatric surgery presented higher RCVD than obese patients without MS (p=0.019). Binary logistic regression revealed patient age [adjusted OR=1.05, 95% CI=1.00-1.11, p=0.042] and number of missing teeth [adjusted OR=1.17, 95% CI=1.04-1.31, p=0.013] to be significant predictors of MS. Conclusion: Morbidly obese patients with MS had worse oral and systemic conditions than those without MS, regarding WHR, RCDV and number of missing teeth. Department of Pediatric Dentistry Orthodontics and Public Health Bauru School of Dentistry University of São Paulo Department of Operative Dentistry Endodontics and Dental Materials Bauru School of Dentistry University of São Paulo Department of General Surgery Botucatu School of Medicine University of State of São Paulo Department of Surgery Faculty of Medical Sciences State University of Campinas FAPESP: 2013/19691-3

This study evaluated the protective effect of TiF4 varnish, after pre-treatment with proantocyanidin or chlorhexidine, on the progression of erosive dentin loss (EDL), under the presence or absence of the demineralized organic matrix (DOM). Bovine root dentin samples were eroded for 30 min (0.1% citric acid, pH 2.5) and the loss was measured by profilometry. Half of them were subjected to the DOM removal using collagenase for 4 days, while the other half remained immersed in water. The removal of DOM was checked by profilometry. Samples were divided into 24 groups (n = 15) according to the factors: 1– With or without DOM; 2– Pre-treatment with 0.012% chlorhexidine gel, 10% proanthocyanidin gel or untreated for 1 min; 3–Final Treatment with TiF4 varnish, NaF varnish, placebo varnish or untreated for 6 h. The samples were submitted to a pH cycling for 5 days: 0.1% citric acid (4 × 90s/day) and artificial saliva between the challenges. The final profile was obtained for the calculation of EDL (μm, three-way ANOVA/Tukey test). When DOM was preserved, the EDL was lower compared to the condition without DOM (7.08 ± 4.03 μm and 9.80 ± 3.79 μm, p

This study evaluated the staining potential of TiFOne hundred and eighty bovine enamel samples were polished; half of them remained sound and the other half was eroded (4 × 90 s each, using a 0.1% citric acid). Thereafter, the baseline color reading was performed (TTiFThe color changes induced by the experimental TiFBoth TiF

To evaluate the in vitro abrasive effect of commercial whitening toothpastes on eroded bovine enamel samples in respect to erosive tooth wear.72 bovine crowns were embedded, polished and subjected to the baseline profile analysis. The samples were then protected in 2/3 of the enamel surface and were randomly assigned to six groups (n= 12/group): G1: Oral-B 3D White, G2: Close-up Diamond Attraction Power White, G3: Sorriso Xtreme White 4D, G4: Colgate Luminous White, G5: Crest (conventional toothpaste), G6:erosion only (control). All samples were submitted to an erosive pH cycling (4 x 90 seconds in 0.1% citric acid, pH 2.5, per day) and abrasive challenges (2 x 15 seconds, per day) for 7 days. After the first and the last daily cycles, the samples were subjected to abrasive challenges, using a toothbrushing machine, soft toothbrushes and slurry of the tested toothpastes (1.5 N). Between the challenges, the samples were immersed in artificial saliva. The final profile was obtained and overlaid to the baseline profile for the calculation of the erosive tooth wear (μm). The data were subjected to Kruskal-Wallis/Dunn tests (P0.05).G1 promoted the highest enamel wear (3.68±1.06 μm), similarly to G3 (3.17± 0.80 μm) and G4 (3.44± 1.29 μm). G3 and G4 performed similarly between them and compared with G5 (2.35± 1.44 μm). G2 (1.51± 0.95 μm) and G6 (0.85± 0.36 μm) showed the lowest enamel wear, which did not differ between them and from G5. Oral-B 3D White showed the highest abrasive potential while Close-up Diamond Attraction Power White showed the lowest abrasive potential on eroded enamel in vitro.This study showed that some commercial whitening toothpastes, especially those containing pyrophosphate associated with hydrated silica, enhanced enamel erosive wear.

Made available in DSpace on 2022-04-28T19:04:55Z (GMT). No. of bitstreams: 0 Previous issue date: 2016-10-01 Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) Society has changed its own lifestyle, specially its eating habits and physical activities, leading to excessive weight and a sedentary behavior, which has contributed to obesity increase. Bariatric surgery is the most effective treatment to obesity, allowing weight loss and its maintenance. However, it has been related high levels of iron deficiency after surgery. A person's nutritional status might be affected by total or partial tooth loss. The aim of this longitudinal prospective cohort study was to evaluate the levels of serum ferritin before and after bariatric surgery and to identify if there is a relation with tooth loss. The sample was composed of 50 patients selected and assisted at Amaral Carvalho Hospital, located in Jaú city, Brazil. The use and necessity of prosthesis, dental absence or presence, and serum ferritin dosage were evaluated. Student's t test, Univariate analysis, Chi-square and Odds Ratio were adopted (p

To compare the effect of 5 desensitizing agents on the hydraulic conductance (Lp) of dentin and to analyze its surface under a Laser Scanning Confocal Microscope (LSCM) before and after an erosive challenge.Lp was analyzed in the following sequence: in the presence of smear layer (pMin), after a 15-second acid etching (pMax), after treatment with a desensitizing agent (pTreat) and after a 1-minute erosive challenge (6% citric acid - pEro). Fifty 1.0 ± 0.2 mm-thick dentin disks were prepared from sound human third molars and were randomly distributed into 5 groups (n = 10): FG-Fluoride gel (control), SA-Sensiactive, PR-Sensitive Pro-Relief, NP-Desensibilize Nano-P and EV-Enamel Pro Varnish. Data were analyzed by two-way ANOVA and Tukey tests (α0.05). Additional specimens were analyzed under a Laser Scanning Confocal Microscope (LSCM) and by Energy Dispersive X-ray Spectroscopy (EDS).All materials reduced the Lp in some extent, except for FG and EV. After the erosive challenge, SA was the only material effectively able to keep the same Lp of the post-treatment phase, while the other products showed lower resistance upon an erosive challenge. Under the LSCM, the SA and NP materials were more effective to obliterate the opened dentin tubules and demonstrated higher resistance upon an erosive challenge. The EDS analysis evidenced levels of Ca, O, P, Si, Na and S.Product containing potassium oxalate was the most effective in reducing Lp of dentin samples before and after an erosive challenge. Under a LSCM, products containing potassium oxalate or hydroxyapatite crystals seemed to be occluding the dentin tubules after an erosive challenge.