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Made available in DSpace on 2020-12-10T17:37:24Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-01-23 Introduction: The use of herbal medicine is on the rise worldwide, and safety issues associated with herbal medicines may have an exacerbated impact in elderly because this population has an increased susceptibility and sensitivity to health complications due to the aging process. Methods: This cross-sectional study was carried out at a primary health care unit in the city of Macapa, Brazil. The herbal medicines used and the sociodemographic characteristic of 123 voluntarily consenting participants were collected using a structured questionnaire. A total of 132 herbal medicines with oral or topical administration were donated by the elderly for microbial analysis before consumption, and 18 water samples used in the preparation of homemade herbal medicines were collected. Bacterial and fungal counts and identification of bacterial pathogens (Escherichia coli, Salmonella spp., Pseudomonas aeruginosa and Staphylococcus aureus) were performed according to the regulations of the Brazilian Pharmacopoeia and World Health Organization. Water analysis for the detection of coliforms and E. coli was carried out using Colilert (R) according to the manufacturer's instructions and the techniques established by Standard Methods. Results: Of the study participants, 78.8% were women. Bacterial growth was observed in samples from 51.5% of study and 35.6% had fungal growth. A total of 31.8% of the herbal medicine samples exceeded the safety limits (CFU/g

Made available in DSpace on 2020-12-10T19:36:37Z (GMT). No. of bitstreams: 0 Previous issue date: 2019-10-01 Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) Based on morphology and morphometry of gametocytes in blood and molecular phylogenetic analysis, we described a new species of hemoparasite from the genus Haemogregarina isolated from Lepidosiren paradoxa in the eastern Amazon region. Haemogregarina daviesensis sp. nov. is characterized by monomorphic gametocytes of varying maturity stage and their dimensions were 16 +/- 0.12 mu m (range 13-18) in length and 6 +/- 0.97 mu m (range 5-8) in width. The morphological and morphometric data were not identical with other haemogregarine species from fish. All specimens of L. paradoxa analyzed were infected by H. daviesensis sp. nov. and the parasitemia level was moderate (1-28/2000 blood erythrocytes). Two sequences were obtained from L. paradoxa, and these constituted a monophyletic sister clade to the Haemogregarina species. In addition, H. daviesensis sp. nov. detected here grouped with Haemogregarina sp. sequences isolated from chelonian Macrochelys temminckii, with 99% bootstrap support. This study provides the first data on the molecular phylogeny of an intraerythrocytic haemogregarine of freshwater fish and highlights the importance of obtaining additional information on aspects of the general biology of these hemoparasites in fish populations, in order to achieve correct taxonomic classification. Univ Fed Amapa, Dept Ciencias Biol & Saude, Rodovia Juscclino Kubitscheck,KM 02 S-N, BR-68903419 Macapa, Amapa, Brazil Univ Estadual Paulista, Inst Biociencias, Dept Parasitol, BR-18618970 Botucatu, SP, Brazil Embrapa Amapa, Rodovia Juscelino Kubitscheck,Km 5,2600, BR-68903419 Macapa, Amapa, Brazil Univ Estadual Paulista, Inst Biociencias, Dept Parasitol, BR-18618970 Botucatu, SP, Brazil CNPq: 303013/2015-0

Background: the purpose of this study was to analyze the importance of traditional medicinal plants use to Wajapi women in the State of Amapa, Brazil, as well as their practices in the local common illnesses of treatment considering the prevailing practice by non-Indians.Methods: This study was conducted in the Community of the Wajapi Indigenous People, a Brazilian territory located in the central western State of Amapa. Wajapi women were selected for the interview since they have the responsibility to harvest, collect and prepare the preparations. the studied women were residents of four villages. the number of women within these four villages is 24.Results and conclusions: the findings fell into the following three categories: 1) the daily use of medicinal plants by women and main methods of application. in this category, the botanical families found included Leguminosae-Caesalpinoideae, Anacardiaceae, Meliaceae, and Rubiaceae. the main forms of use found were teas, baths, maceration, in natura, and juices; 2) Through analysis of illness and treatment records, a lack of knowledge integration in the health system was shown to be due to a variety of gaps and the need of health professionals to be more aware about the local culture which they intend to work with, what could decrease the prevailing barriers between the social groups involved; 3) Traditional knowledge and possible sustainability can be fostered by stimulating the transmission of traditional knowledge from generation to generation, therefore reducing the dependence on industrialized medicines and also by maintaining an appreciation of those practices among youngsters, who tend to question them. Univ Fed Amapa, Curso Enfermagem, Ctr Ciencias Biol & Saude, BR-68902280 Macapa, Amapa, Brazil Univ Fed Amapa, Lab Estudos Sociais, BR-68902280 Macapa, Amapa, Brazil Universidade Federal de São Paulo Unifesp, DCET, Setor Ciencias Farmaceut, BR-09972270 Diadema, SP, Brazil Univ Fed Amapa, Lab Pesquisa Farm, Ctr Ciencias Biol & Saude, BR-68902280 Macapa, Amapa, Brazil Universidade Federal de São Paulo Unifesp, DCET, Setor Ciencias Farmaceut, BR-09972270 Diadema, SP, Brazil Web of Science