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Additional file 2: Supplemental Figure 2. Prevalence of non-PE related mechanical ventilation requirement and shock among patients among (A) pre-PERT and PERT-era patients and (B) Pert activated and non-PERT activated subjects in the PERT era; MV, mechanical ventilation, shock is defined as hypotension requiring vasopressor medication. * p

Additional file 3: Supplementary Table 1 Performed risk assessment and severity of PE. Abbreviations: PP; pre-PERT; PA, PERT alerted; NPA, Non-PERT alerted; BNP, Brain natriuretic peptide; TTE, transthoracic echocardiogram; RV, right ventricle; CT, computer tomography. a) assessment within 12 h of pulmonary embolism diagnosis, b) positive RV strain by biomarkers was determined as troponin> 0.02 ng/mL, and/or BNP > 155 pg/mL; c) RV strain on CT imaging was determined as RV/LV ration (ratio of right ventricular to left ventricular diameter ration of > 0.9). P value calculated by Chi Square test.

Additional file 1: Supplemental Figure 1. Distribution of 2019 ESC risk categories among the 3 groups. ESC, European Society of Cardiology.