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Supplementary light aerobic exercise in normoxic conditions could be beneficial for trained individuals in order to reduce the physiological alterations on the cardiopulmonary system induced by altitude exposure.

A method for skeletal muscle injury induction in trained rats is described and validated by means of the monitorization of several skeletal muscle injury plasma markers.

ELISA tests on plasma were used as a rapid method to determine the existence of muscle damage in trained rats. Myoglobin in plasma showed a different dynamics in the active recovery group, perhaps indicating a different degree of injury in theoxidative fibres. However, the CK level might not be the best representative parameter to accurately evaluate the actual level of the muscle damage produced.

Intermittent hypobaric hypoxia and light aerobic exercise could be beneficial for a skeletal muscle damage recovery. Rats combining hypoxic exposure and light runing for 15 minutes showed a higher increase of haematopoietic stem cells inthe peripheral blood after muscle damage.

In rat soleus muscle, a recuperation programme of IHH combined with light exercise seems to induce a fasterrecovery of the mean muscle fibres size and a significant decrease in the percentage of abnormal fibres, without affecting neither the percentage of fibre types nor the fibre shape.