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Frontiers in psychiatry 13, 920665 (2022). doi:10.3389/fpsyt.2022.920665, Published by Frontiers Research Foundation, Lausanne

Figure S1. Expression of ANXA3 using RT-PCR: delta Ct values (relative expression values related to RPL) in controls, active systemic or polyarticular disease and inactive disease (***p

Figure S1. Bronchial hyperresponsiveness in C57BL6 mice in LPS-induced acute lung injury. Mice were instilled with 50 μL of LPS (4 mg/kg) or saline (controls) on day 0 and were mechanically ventilated 1, 4 or 10 days after ARDS induction. Mice of basal group were mechanical ventilated without prior i.t. instillation. (A-D) Lung function parameters resistance (Rrs), elastance (Ers), tissue damping (G) and tissue elastance (H) on day 1, 4 and 10 after ARDS-induction following acetylcholine stimulation (controls n = 4, ARDS group n = 6 per time point, means ± SEM). * p ≤ 0.05, ** p ≤ 0.01, *** p ≤ 0.001. (PDF 311 kb)

Figure S2. Bronchial hyperresponsiveness in RAG2−/− and wildtype mice in LPS-induced acute lung injury. Mice were instilled with 50 μL of LPS (4 mg/kg) on day 0 and were mechanically ventilated 1, 4 or 10 days after ARDS induction. (A-D) Lung function parameters resistance (Rrs), elastance (Ers), tissue damping (G) and tissue elastance (H) on day 1, 4 and 10 after ARDS-induction following acetylcholine stimulation) (n = 8 in each group at each time point, means ± SEM). * p ≤ 0.05, ** p ≤ 0.01, *** p ≤ 0.001. (PDF 304 kb)