1. Evidence-based Care Bundles for Preventing Surgical Site Infections in Spinal Instrumentation Surgery
- Author
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Haruko Fujii, Juichi Tonosu, Hiroaki Abe, Akiro Higashikawa, Hiroshi Okazaki, Tomohiro Shinozaki, Takashi Kuniya, Koji Yamada, Kazuki Niwa, Koji Nakajima, Tanaka Sakae, and Kenichi Watanabe
- Subjects
Male ,Methicillin-Resistant Staphylococcus aureus ,medicine.medical_specialty ,03 medical and health sciences ,0302 clinical medicine ,Vancomycin ,Surgical site ,medicine ,Humans ,Surgical Wound Infection ,Orthopedic Procedures ,Orthopedics and Sports Medicine ,030212 general & internal medicine ,Care bundle ,Antibiotic prophylaxis ,Patient Care Bundle ,Povidone-Iodine ,Aged ,Retrospective Studies ,Aged, 80 and over ,Cross Infection ,Evidence-Based Medicine ,Spinal instrumentation ,business.industry ,Retrospective cohort study ,Evidence-based medicine ,Antibiotic Prophylaxis ,Middle Aged ,Staphylococcal Infections ,Anti-Bacterial Agents ,Surgery ,Anti-Infective Agents, Local ,Female ,Spinal Diseases ,Neurology (clinical) ,business ,Surgical site infection ,Patient Care Bundles ,030217 neurology & neurosurgery - Abstract
A retrospective study, using prospectively collected data.The aim of this study was to evaluate the impact of evidence-based care bundles for preventing surgical site infections (SSIs) in spinal instrumentation surgery.About half of all SSIs are preventable via evidence-based methods. For successful SSI prevention, the bacterial load must be minimized, and methicillin-resistant Staphylococcus aureus (MRSA) protection must be maximized. However, it is difficult to cover all of these requirements by single preventative method.We screened consecutive patients scheduled for spinal instrumentation surgeries at a single tertiary referral hospital for high surgical, SSI, and MRSA colonization risks. Evidence-based care bundles were implemented for high-risk patients and included 1) additional vancomycin prophylaxis, 2) diluted povidone-iodine irrigation, and 3) nasal and body decontamination. Patient demographics, comorbidities, operative features, and SSIs reported to the Japanese Nosocomial Infections Surveillance system were prospectively obtained in the same method by the same assessor and were used for the analyses. The results were compared before and after the application of the bundle.There were 1042 spinal instrumentation surgeries (741 before and 301 after care bundles) performed from November 2010 to December 2015. Of 301 surgeries, 57 cases (18.9%) received care bundles. There were no significant differences in patient backgrounds before and after the intervention. The SSI rate decreased significantly from 3.8% to 0.7% (P 0.01) after the intervention, with an overall 82% relative risk reduction. A significant protective effect was observed in the multivariate analysis (adjusted odds ratio 0.18, 95% confidence interval: 0.04-0.77, P = 0.02). There were no MRSA-related SSIs among those that received care bundles, even though MRSA was the predominant pathogen in the study population.Evidence-based care bundles, applied in selected high-risk spinal instrumentation cases, minimized bacterial load, maximized MRSA protection, and significantly reduced SSI rates without topical vancomycin powder.4.
- Published
- 2018