36 results on '"Takeshi Aikawa"'
Search Results
2. Fractures of the Second Cervical Vertebra in 66 Dogs and 3 Cats: A Retrospective Study
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Aurelien Jeandel, Nick D. Jeffery, Fenella E. Schmidli, Konrad Jurina, Veronika M. Stein, Beatriz Vidondo, Pierre Henri Moissonnier, Stefan Rupp, Randy J. Boudrieau, Franck Forterre, and Takeshi Aikawa
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Male ,medicine.medical_specialty ,Ataxia ,Tetraparesis ,Second cervical vertebra ,Dogs ,medicine ,Animals ,610 Medicine & health ,Tetraplegia ,Retrospective Studies ,CATS ,General Veterinary ,business.industry ,Accidents, Traffic ,Retrospective cohort study ,Perioperative ,medicine.disease ,Surgery ,Treatment Outcome ,Ambulatory ,Cats ,Cervical Vertebrae ,570 Life sciences ,biology ,590 Animals (Zoology) ,Spinal Fractures ,Female ,Animal Science and Zoology ,medicine.symptom ,business - Abstract
Background In human medicine, fractures of the second cervical vertebra have been studied elaborately and categorized in detail. This is not the case in veterinary medicine where clinical decisions are often based on old studies focusing on the cervical spine in general. Objectives The aim of this study was to describe the clinical features, fracture types, therapeutic options and outcome of dogs and cats with a fractured axis. Study Design The present study was a multi-institutional retrospective case series. Results Crossbreeds and Labrador Retrievers were the most represented dog breeds. Median age was 2 years. Motor vehicle accident was the most common inciting cause, followed by frontal collision. The most common neurological deficits ranged from cervical pain with or without mild ataxia (22/68) to tetraparesis (28/68) and tetraplegia (11/68). Concerning treatment, 37 of 69 patients underwent surgical fracture stabilization, 27/69 received conservative therapy and 5/69 were immediately euthanatized. Of all treated cases, 52/58 showed ambulatory recovery (23/25 of the conservatively treated and 29/33 of the surgically treated cases), whereby in 40/52 cases full recovery without persisting signs was achieved. Conclusions Fractures of the axis commonly occur in young dogs. In many cases, neurological deficits are relatively mild. Generally, animals with a fractured axis have a very good prognosis for functional recovery. The risk of perioperative mortality is considerably lower than previously reported.
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- 2019
3. Hemilaminectomy, Diverticular Marsupialization, and Vertebral Stabilization for Thoracolumbar Spinal Arachnoid Diverticula in Five Dogs
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Taichi Shimatsu, Takeshi Aikawa, and Yuta Miyazaki
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Male ,medicine.medical_specialty ,040301 veterinary sciences ,Radiography ,medicine.medical_treatment ,Spinal Cord Diseases ,0403 veterinary science ,Lesion ,03 medical and health sciences ,Dogs ,Animals ,Medicine ,Dog Diseases ,Small Animals ,Spinal cord injury ,Myelography ,Retrospective Studies ,030304 developmental biology ,0303 health sciences ,medicine.diagnostic_test ,business.industry ,Laminectomy ,Magnetic resonance imaging ,Retrospective cohort study ,04 agricultural and veterinary sciences ,Marsupialization ,Spinal cord ,medicine.disease ,Magnetic Resonance Imaging ,Surgery ,medicine.anatomical_structure ,Female ,medicine.symptom ,business ,Spinal Cord Compression - Abstract
Medical records (2004–2016) of five dogs with a thoracolumbar spinal arachnoid diverticula (SAD) that was diagnosed with stress myelography in four dogs and magnetic resonance imaging in three, and who had hemilaminectomy, diverticular marsupialization, and vertebral stabilization, were reviewed. Data on previous treatment, pre- and postoperative neurologic status, diagnostic findings, surgical techniques, and outcomes was retrieved. Follow-up clinical and radiographic evaluations were performed immediately; ∼1, 2, and 6 mo postoperatively; and at annual follow-up examinations. The stress myelography demonstrated spinal cord dynamic compression in three of four dogs and change in size or shape of the SAD in all four. Two dogs who had SAD recurrences 4 and 13 mo after previous surgical dural fenestration, and one dog with no previous SAD treatment demonstrated long-term neurological improvement after vertebral stabilization (49, 77, and 126 mo). In two other dogs, recurrence of clinical signs was observed at the follow-up (8 and 12 mo). This case series suggested that repetitive spinal cord injury from the dynamic lesion appears to be one potential cause of thoracolumbar SADs. In cases with dynamic lesions confirmed by stress myelography, vertebral stabilization with conventional techniques is indicated to prevent SAD recurrence.
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- 2019
4. Long-Term Outcome After Surgical Resection of a Spinal Choroid Plexus Tumor in a Dog
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Takeshi Aikawa, Yuta Miyazaki, Masaaki Nishimura, and Yuya Saitoh
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Surgical resection ,Male ,medicine.medical_specialty ,Choroid Plexus Neoplasms ,040301 veterinary sciences ,Central nervous system ,Fourth ventricle ,Postural reactions ,0403 veterinary science ,Lesion ,03 medical and health sciences ,0302 clinical medicine ,Dogs ,Spinal cord compression ,medicine ,Animals ,Dog Diseases ,Spinal Cord Neoplasms ,Small Animals ,Choroid plexus tumor ,business.industry ,04 agricultural and veterinary sciences ,Glioma ,medicine.disease ,Clumber Spaniel ,Surgery ,medicine.anatomical_structure ,Treatment Outcome ,medicine.symptom ,business ,030217 neurology & neurosurgery - Abstract
A 6 yr old castrated male Clumber spaniel was referred for evaluation of acute paraplegia. MRI of the thoracolumbar spine demonstrated an intradural-extramedullary mass lesion at the level of T12 and extradural spinal cord compression at L1–L2. A hemilaminectomy was performed to achieve gross total resection of the mass lesion and removal of extruded disc material. A diagnosis of spinal choroid plexus tumor (CPT) and intervertebral disc extrusion was made. At 4 mo postoperatively, MRI demonstrated a mass lesion at the right lateral aperture of the fourth ventricle. Spinal drop metastasis from a primary intracranial CPT was suspected. The dog was ambulating independently and neurologically normal at that time. At 17 mo postoperatively, a third MRI was performed owing to decreased postural reactions in both hind limbs and vision loss in the right eye, and it demonstrated an increase in size of the intracranial mass lesion. These two additional MRI studies of the entire central nervous system showed no other metastatic lesions nor any evidence of local recurrence. At 25 mo postoperatively, the dog died at home. This is the first case report of surgical intervention and antemortem histopathological diagnosis of a spinal CPT in a dog.
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- 2020
5. Relation between thresholds of free radical generation and atomization under ultrasound exposure
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Takeshi Aikawa and Nobuki Kudo
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Materials science ,Physics and Astronomy (miscellaneous) ,business.industry ,Cavitation ,Acoustics ,Ultrasound ,General Engineering ,General Physics and Astronomy ,Sound field ,Ultrasound exposure ,business ,Ultrasonic atomization - Abstract
The relationship between thresholds of free radical generation and atomization under ultrasound exposure was investigated to elucidate the mechanisms of ultrasonic atomization. In the experiments to gradually increase the transducer driving voltage, the free radical generation, a quick transition of the water surface shape from a protuberance to a fountain, and atomization had the same threshold. The experiments using the acoustic loading conditions with the different water surface shapes also confirmed this fact. Furthermore, a focused shadowgram of the ultrasound field taken using a small container that mimics the protuberance visualized the generation of spotty-shaped high-intensity nodes inside and near the boundary of the protuberance. These results indicate that the induction of cavitation promoted by the high-intensity nodes triggers the appearance of the fountain that leads to the creation of atomization.
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- 2021
6. Analysis of Biological Response to Pleasure Elicited by Video
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Toru Yokoyama, Takeshi Aikawa, Masaji Yamashita, and Masataka Kitama
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medicine.medical_specialty ,media_common.quotation_subject ,Audiology ,Disgust ,Pleasure ,Pulse pressure ,Mean blood pressure ,Blood pressure ,Heart rate ,Happiness ,medicine ,Plethysmograph ,Psychology ,media_common - Abstract
To study the objective evaluation of emotions, and pleasure in particular, biological responses to emotional videos were investigated. Fifteen adult males participated in the experiment. Five videos were used, which engendered “exhilaration,” “happiness,” “being comforted,” “disgust,” and “control.” Impedance plethysmography, electrocardiogram, photo plethysmography, continuous blood pressure, and respiration were measured and analyzed. Self-rated scores for “pleasure–displeasure” adequately varied among emotional-video stimuli. Biological changes were observed in the “exhilaration” condition, such as heart rate (HR), pulse wave amplitude, and pulse pressure. However, no biological changes in common were found among pleasurable emotions. To determine biological responses common to pleasurable emotions, the pulse wave was assessed in detail. Consequently, arterial compliance tended to decrease for each pleasurable emotion, albeit non-significantly. The maximum of the differentiated pulse wave (dP) changed significantly for “exhilaration” and “happiness.” Moreover, the combined parameter, which involved dP, HR, and mean blood pressure changed significantly for all pleasurable emotions.
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- 2018
7. Clinical Outcomes and Complications after Open Reduction and Internal Fixation Utilizing Conventional Plates in 65 Distal Radial and Ulnar Fractures of Miniature- and Toy-Breed Dogs
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Kyoko Iizuka, Yuta Miyazaki, Takeshi Aikawa, Masaaki Nishimura, and Taichi Shimatsu
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medicine.medical_specialty ,040301 veterinary sciences ,medicine.medical_treatment ,Body weight ,0403 veterinary science ,Fixation (surgical) ,Fracture Fixation, Internal ,Dogs ,Bone plate ,Fracture fixation ,medicine ,Internal fixation ,Animals ,Plate fixation ,Retrospective Studies ,General Veterinary ,business.industry ,0402 animal and dairy science ,04 agricultural and veterinary sciences ,040201 dairy & animal science ,Ulna Fractures ,Surgery ,Ulnar fractures ,Treatment Outcome ,Animal Science and Zoology ,business ,Complication ,Radius Fractures ,Bone Plates - Abstract
Objective This article aims to evaluate clinical outcomes and complications of distal radial and ulnar fractures in miniature- and toy-breed dogs treated with conventional bone plate fixation. Methods Medical records (2001–2010) of miniature- and toy-breed dogs with distal radial and ulnar fractures repaired with open reduction and internal fixation utilizing conventional plates were reviewed. The inclusion criteria were body weight of Results All 65 fractures healed without developing non-union, and had a successful return to normal function (median follow-up: 73 months; range: 2–149 months). Minor complication in seven fractures and major complication in four fractures were identified. Clinical Significance Open reduction and conventional plate fixation of distal radial and ulnar fractures in miniature- and toy-breed dogs are effective means of fixation that result in normal functional outcome without developing non-union.
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- 2018
8. Clinical outcomes of 119 miniature- and toy-breed dogs with 140 distal radial and ulnar fractures repaired with free-form multiplanar type II external skeletal fixation
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Shigeo Sadahiro, Yuta Miyazaki, Takeshi Aikawa, Masaaki Nishimura, and Yuya Saitoh
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Male ,medicine.medical_specialty ,040301 veterinary sciences ,Radiography ,Joint Dislocations ,0403 veterinary science ,03 medical and health sciences ,Fixation (surgical) ,0302 clinical medicine ,Dogs ,Fracture Fixation ,medicine ,Animals ,Body Size ,Clinical significance ,Joint dislocation ,Dog Diseases ,Device Removal ,Retrospective Studies ,General Veterinary ,business.industry ,Osteomyelitis ,External skeletal fixation ,Retrospective cohort study ,04 agricultural and veterinary sciences ,medicine.disease ,Ulna Fractures ,Surgery ,Splints ,Treatment Outcome ,030220 oncology & carcinogenesis ,Female ,business ,Radius Fractures ,Bone Plates - Abstract
Objective To report the clinical outcomes of miniature- and toy-breed dogs with primary and previously treated distal radial and ulnar fractures (RUF) treated with a free-form multiplanar type II external skeletal fixation (ESF). Study design Retrospective study. Animals One hundred nineteen dogs with 140 distal RUF. Methods Medical records (2003-2017) were reviewed for dogs weighing up to 7 kg that had been treated for distal RUF with a free-form multiplanar type II ESF. Data collected included signalment, fracture location and configuration, fracture reduction, intraoperative realignment, time to bone union and implant removal, duration of destabilization and postoperative splint, complications, and outcomes. Follow-up consisted of clinical and radiographic evaluation or telephone interview. Results All fractures healed, with a median time of 60 days, and entire ESF was removed, with a median time of 89 days. Major complications occurred in four fractures: premature pin loosening, elbow subluxation, osteomyelitis, and delayed union. Minor complications occurred in 52 fractures (61 events). All dogs had a successful return to normal limb function at final follow-up (median, seven months; range, 2-97). Conclusion All primary and previously treated distal RUF in miniature- and toy-breed dogs healed and allowed return to normal function after fixation with a free-form multiplanar type II ESF. Clinical significance The free-form multiplanar type II ESF provides an alternative for minimally invasive fixation of distal RUF in miniature- and toy-breed dogs that facilitates fracture reduction, intraoperative realignment, adequate initial fixation stability, destabilization, and implant removal.
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- 2018
9. Primary colonic hemangiosarcoma in a dog
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Munetaka, Iwata, Takeshi, Aikawa, Yuta, Miyazaki, and Shigeo, Sadahiro
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body regions ,Dogs ,embryonic structures ,Colonic Neoplasms ,Hemangiosarcoma ,Liver Neoplasms ,Animals ,Female ,Scientific ,Dog Diseases - Abstract
A 13-year-old spayed female miniature dachshund dog was presented with a history of hematochezia, melena, and weight loss. A colonic mass detected by exploratory celiotomy was resected and diagnosed as hemangiosarcoma (HSA). Liver lobectomy for hepatic HSA was performed 894 days after surgery. Adjuvant chemotherapy was declined. This is the first documentation of a canine colonic HSA.
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- 2018
10. Incidence of Abnormalities of the Second and Third Cervical Vertebral Junction in Dogs with Atlantoaxial Instability: A Multicentre Study
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Takeshi Aikawa, Maja Alice Waschk, M Schneider, D Schnötzinger, Pierre Henri Moissonnier, Franck Forterre, D Garosi, Christina Nathues, Martin J. Schmidt, and Maria Christina Precht
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Joint Instability ,Male ,040301 veterinary sciences ,Radiography ,0403 veterinary science ,03 medical and health sciences ,0302 clinical medicine ,Dogs ,medicine ,Animals ,Dog Diseases ,Pathological ,Retrospective Studies ,General Veterinary ,medicine.diagnostic_test ,Atlanto-axial joint ,business.industry ,Incidence ,Magnetic resonance imaging ,Intervertebral disc ,04 agricultural and veterinary sciences ,Anatomy ,medicine.disease ,Magnetic Resonance Imaging ,Hypoplasia ,medicine.anatomical_structure ,Atlanto-Axial Joint ,Atlantoaxial instability ,Case-Control Studies ,Cervical Vertebrae ,Animal Science and Zoology ,Female ,business ,030217 neurology & neurosurgery ,Cervical vertebrae - Abstract
Objective To evaluate the occurrence and frequency of abnormalities at the second and third cervical vertebral junction (C2/3) in dogs with and without atlantoaxial instability (AAI). Study Design Retrospective multi-institutional case-controlled case series. Animals One hundred and seventeen dogs with AAI and 117 dogs without AAI. Methods Radiographs, together with computer tomographic images or magnetic resonanceimagesorboth, of thecranial cervical spineof dogswerereviewed for the presence or absence of intervertebral disc–related anomalies, osseous fusion of the vertebrae, spondylosis, or any other anomaly of the C2/3. Results The incidence of anomalies affecting the C2/3 in dogs with AAI was 38.46% (n = 45) and in the control group it was 11.97% (n = 14). The majority of the observed anomalies involved the intervertebral disc. In conjunction with AAI, intervertebral disc– related anomalies were noted in 33.34%, spondylosis in 2.56%, osseous fusion in 1.71% and a hypoplasia of the spinous process in 0.85% of the cases. Summarized under the term intervertebral disc–related anomalies, a morphological alteration of the intervertebral disc was noted in 10 cases with AAI, characterized by a spherical outer shape and a minimally reduced size and a dorsal positioning in the intervertebral space. Conclusion There is a significantly higher incidence of anomalies affecting the C2/3 in associationwithAAI.InconjunctionwithAAI, intervertebraldisc–related anomalies are the mostfrequentpathological finding affecting the C2/3.
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- 2017
11. Enhancement of Runx2 Expression Is Potentially Linked to β-Catenin Accumulation in Canine Intervertebral Disc Degeneration
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Yasushi Hara, Munetaka Iwata, Yoshinori Asou, Kiyotaka Arai, Takaharu Hakozaki, Hirotaka Haro, Masahiro Tagawa, Takeshi Aikawa, and Hiroki Ochi
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Physiology ,Clinical Biochemistry ,Wnt signaling pathway ,Intervertebral disc ,Cell Biology ,Anatomy ,Biology ,Matrix metalloproteinase ,medicine.disease ,Cell biology ,RUNX2 ,medicine.anatomical_structure ,Downregulation and upregulation ,Catenin ,Gene expression ,medicine ,Calcification - Abstract
Intervertebral disc degeneration (IVDD) greatly affects the quality of life. The nucleus pulposus (NP) of chondrodystrophic dog breeds (CDBs) is similar to the human NP because the cells disappear with age and are replaced by fibrochondrocyte-like cells. Because IVDD develops as early as within the first year of life, we used canines as a model to investigate the in vitro mechanisms underlying IVDD. The mechanism underlying age-related IVDD, however, is poorly understood. Several research groups have suggested that Wnt/β-catenin signaling plays an important role in IVDD. However, the role of Wnt/β-catenin signals in IVD cells is not yet well understood. Here, we demonstrate that Wnt/β-catenin signaling could enhance Runx2 expression in IVDD and lead to IVD calcification. Nucleus pulposus (NP) tissue was obtained from Beagle dogs after evaluation of the degeneration based on magnetic resonance imaging (MRI). Histological analysis showed that lack of Safranin-O staining, calcified area, and matrix metalloproteinase (MMP) 13-positive cells increased with progression of the degeneration. Furthermore, the levels of β-catenin- and Runx2-positive cells also increased. Real-time reverse-transcription polymerase chain reaction analysis showed that the MRI signal intensity and mRNA expression levels of β-catenin and Runx2 are correlated in NP tissues. Moreover, supplementation of LiCl induced β-catenin accumulation and Runx2 expression. In contrast, FH535 inhibited LiCl-induced upregulation. These results suggest that Runx2 transcript and protein expression, potentially in combination with β-catenin accumulation, are enhanced in degenerated and calcified intervertebral discs of CDBs.
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- 2014
12. A Comparison of Thoracolumbar Intervertebral Disc Extrusion in French Bulldogs and Dachshunds and Association With Congenital Vertebral Anomalies
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Yasushi Hara, Mitsuhiro Shibata, Takeshi Aikawa, Masahiro Tagawa, Moe Asano, and Hiromitsu Orima
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musculoskeletal diseases ,medicine.medical_specialty ,General Veterinary ,business.industry ,Kyphosis ,Lumbar vertebrae ,musculoskeletal system ,medicine.disease ,Vertebral anomalies ,eye diseases ,Surgery ,medicine.anatomical_structure ,Lumbar ,Thoracic vertebrae ,medicine ,Paraplegia ,business ,Myelomalacia ,Kyphoscoliosis - Abstract
Objectives To compare data for French Bulldogs and Dachshunds that had hemilaminectomy for thoracolumbar intervertebral disc extrusion (T-L IVDE) by 1 surgeon and to evaluate the association between IVDE and congenital vertebral anomalies. Design Retrospective case series. Animals French Bulldogs (n = 47) and 671 Dachshunds. Methods Age, gender, vertebral anomaly, kyphosis/kyphoscoliosis, IVDE site, non-recovery and progressive hemorrhagic myelomalacia development from grade 5 (paraplegia without deep nociception) were compared between the 2 breeds. Results French Bulldogs were significantly younger (P = .00001), more likely to be male (P = .023), and more likely to have a congenital vertebral anomaly and kyphosis/kyphoscoliosis (P
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- 2014
13. Use of skin stretchers for single-stage bilateral mastectomies in a dog and a cat
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Takeshi Aikawa, Yuta Miyazaki, Taichi Shimatsu, Shigeo Sadahiro, and Masaaki Nishimura
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Intact female ,medicine.medical_specialty ,040301 veterinary sciences ,Bilateral mastectomy ,Cat Diseases ,Surgical Flaps ,0403 veterinary science ,03 medical and health sciences ,0302 clinical medicine ,Dogs ,Mammary Glands, Animal ,medicine ,Animals ,Major complication ,Dog Diseases ,Mastectomy ,Wound Healing ,integumentary system ,General Veterinary ,Single stage ,business.industry ,04 agricultural and veterinary sciences ,Cable tension ,Surgery ,030220 oncology & carcinogenesis ,Cats ,Wound closure ,Spayed Female ,Female ,Clinical case ,business - Abstract
Objective To describe the application of skin stretchers for closure of single-stage bilateral mastectomies in a dog and a cat. Study Design Clinical case report. Animals A 12-year-old intact female Miniature Dachshund and a 13-year-old spayed female domestic short-hair cat. Methods Skin stretchers were applied to the site of the skin adjacent to mammary glands for 2-4 days before surgery. Cable tension was adjusted every 6-8 hours to elongate the skin and to achieve primary closure of single-stage bilateral mastectomy without tension. Results Wound closure after single-stage bilateral mastectomy was achieved without tension or major complication in both animals. Conclusion Use of skin stretchers allows primary closure of single-stage bilateral mastectomy in dogs and cats.
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- 2016
14. Visualization of wall propagation and surface reflection effects on ultrasound fields generated inside a small container
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Takeshi Aikawa and Nobuki Kudo
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Materials science ,Physics and Astronomy (miscellaneous) ,business.industry ,Acoustics ,Ultrasound ,Container (abstract data type) ,General Engineering ,General Physics and Astronomy ,Surface reflection ,business ,Visualization - Published
- 2019
15. Modified Ventral Stabilization Using Positively Threaded Profile Pins and Polymethylmethacrylate for Atlantoaxial Instability in 49 Dogs
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Mitsuhiro Shibata, Takeshi Aikawa, and Hiroshi Fujita
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medicine.medical_specialty ,General Veterinary ,Atlanto-axial joint ,business.industry ,Medical record ,Retrospective cohort study ,Perioperative ,medicine.disease ,Surgery ,medicine.anatomical_structure ,Atlantoaxial instability ,Ambulatory ,medicine ,Joint dislocation ,business ,Cancellous bone - Abstract
Objective To describe diagnostic findings, complications, and long-term outcome of dogs with atlantoaxial instability (AAI) that had modified ventral stabilization with positively threaded profile pins and polymethylmethacrylate by 1 surgeon and to evaluate the potential prognostic indicators. Study Design Retrospective case series. Animals Dogs (n = 49) with AAI. Methods Medical records (2000–2010) of dogs with AAI that had modified ventral stabilization were reviewed. Data on pre- and postoperative neurologic status, diagnostic findings, and outcomes were retrieved. Age, neurologic grade, duration of clinical abnormalities, dens abnormalities, and MRI findings were evaluated as the potential predictors for recovery. Age and cancellous bone grafting were evaluated as the potential predictors of postoperative pin breakage. Results Two dogs died during the perioperative period. In 47 dogs with follow up (median: 29 months; range, 4–110 months), 46 dogs (94%) improved neurologically after surgery, but 1 dog did not become ambulatory. There were no long term complications that resulted in serious neurologic deterioration or that required additional surgery. Partial pin breakage (1–5 pins) occurred in 16 dogs at 1–27.5 months (median, 5 months) without neurologic deterioration. Only the nonambulatory preoperative grade was significantly (P = .002) associated with non/incomplete recovery compared with ambulatory dogs. Conclusions Adequate stabilization of the vertebrae and improved neurologic status were achieved in most dogs with AAI using a modified ventral stabilization technique with positively threaded profile pins and polymethylmethacrylate.
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- 2013
16. Radical resection of feline vaccine-associated sarcoma in seven cats
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Shigeo Sadahiro, Mitsuhiro Shibata, Takeshi Aikawa, and Mitsuteru Okawauchi
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medicine.medical_specialty ,CATS ,business.industry ,medicine ,Vaccine-associated sarcoma ,business ,Radical resection ,Surgery - Published
- 2013
17. Evaluation of Feelings of Excitement Caused by Auditory Stimulus in Driving Simulator Using Biosignals
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Yousuke Tate, Norio Nakayama, Hiroki Seto, Yoshihiro Harada, Haruhiko Nakatsuji, Yuya Hasegawa, Kodai Ito, Takeshi Aikawa, Michiko Ohkura, and Tomoki Tani
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Communication ,Feeling ,business.industry ,media_common.quotation_subject ,Driving simulator ,Human engineering ,Stimulus (physiology) ,business ,Psychology ,media_common ,Cognitive psychology - Abstract
In recent years, Japanese young people are exhibiting less interest in driving. Since we believe that their interest can be increased by in-vehicle systems, in this study, we prepared a driving course that features exciting scenes and measured the biological signals of participants while they drove a driving simulator. We focused on the excitement of driving scenes in experiments using a DS and evaluated the feelings of excitement by EEGs and ECGs. We concluded that SDNN and RRV indexes identify feelings of excitement. In this report, we describe a new experiment and analyze its results, which show the same tendency about feeling excitement between questionnaires and biosignals such as EEGs and ECGs.
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- 2016
18. Cerebral Gemistocytic Astrocytoma in a Cat
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Takeo Minami, Takeshi Aikawa, Mitsuhiro Shibata, Hiroshi Fujita, and Taishi Takahashi
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Radiation therapy ,Pathology ,medicine.medical_specialty ,business.industry ,medicine.medical_treatment ,Gemistocytic Astrocytoma ,medicine ,Histopathology ,Radiology ,business - Published
- 2010
19. Intrapelvic Urethral Rupture and Urethral Stricture Accompanied by Pelvic Fracture in Two Dogs
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Hiroshi Fujita, Mitsuhiro Shibata, Takeshi Aikawa, and Taishi Takahashi
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medicine.medical_specialty ,Urethral stricture ,business.industry ,Urethral sphincter ,Urethral rupture ,Urology ,Urinary incontinence ,Anastomosis ,medicine.disease ,Urethra ,medicine.anatomical_structure ,medicine ,Pelvic fracture ,medicine.symptom ,business ,Pelvis - Published
- 2009
20. Use of Active Pleuroperitoneal Shunt Tube (Denver Shunt) for Idiopathic Chylothrax Refractory to the Thoracic Duct Ligation with Cisterna Chyli Ablation in a Dog
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Taishi Takahashi, Hiroshi Fujita, and Takeshi Aikawa
- Abstract
重度の胸水の為、呼吸困難を示した3歳避妊メス ウィペットが来院した。胸水の細胞診、生化学的検査結果および原因疾患除外により特発性乳び胸と診断した。ニューメチレンブルーを腸間膜リンパ節に注入後、胸管結紮術(TDL)と乳び槽切除術(CCA)を実施した。しかしながら術後も乳び性滲出液の持続が認められたため、10日後に2回目のTDLを実施した。TDL後、リンパ管造影検査により胸管交通が残存していることを確認したことから、能動的胸腔腹腔シャントチューブ(デンバーシャント)も装着した。2回目の手術後、乳び性浸出液の量は徐々に減少し、術後180日目にはシャントチューブからの滲出液の排出は認められなくなった。第1,098病日現在、乳び胸の再発は認められていない。
- Published
- 2009
21. Epidural Idiopathic Sterile Pyogranulomatous Inflammation Causing Spinal Cord Compressive Injury in Five Miniature Dachshunds
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Yuki Yoshigae, Takeshi Aikawa, and Shinichi Kanazono
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Male ,medicine.medical_specialty ,Panniculitis ,Decompression ,Breeding ,Lesion ,Myelopathy ,Dogs ,Spinal cord compression ,medicine ,Animals ,Clinical significance ,Dog Diseases ,Retrospective Studies ,General Veterinary ,medicine.diagnostic_test ,business.industry ,Decompression, Surgical ,medicine.disease ,Spinal cord ,Surgery ,Treatment Outcome ,medicine.anatomical_structure ,Anesthesia ,Female ,medicine.symptom ,business ,Paraplegia ,Spinal Cord Compression ,Myelography - Abstract
Objective— To characterize the clinical signs, diagnostic and surgical findings, and outcome of dogs with idiopathic sterile pyogranulomatous inflammation (ISP) of epidural fat causing spinal cord compression. Study Design— Retrospective study. Animals— Dogs (n=5). Methods— Dogs with epidural ISP (2002–2006) were identified retrospectively. Inclusion criteria were neurologic examination, myelography, and definitive diagnosis of ISP confirmed by surgery and histopathologic examination of epidural spinal cord compressive tissue. Results— The most common clinical sign was paraparesis/paraplegia. No abnormalities were detected by laboratory testing or survey spine radiographs. On myelography, extradural spinal cord compressions were focal (dogs 1, 3, and 5) or multifocal (dogs 2 and 4). Surgical decompression of the spinal cord was completed by hemilaminectomy. Epidural fat collected surgically had pyogranulomatous inflammation of unknown cause and was histologically similar to subcutaneous ISP. All dogs had good long-term neurologic outcome (10–45 months follow-up). Some dogs had episodes of ISP at other sites before or after surgical treatment of epidural ISP, suggesting there may be a systemic form of ISP. Conclusion— Epidural ISP may cause a spinal cord compressive lesion in Miniature Dachshunds, which can be treated by surgical decompression of the spinal cord with or without administration of adjunctive steroids. Clinical Relevance— Epidural ISP should be considered as a possible cause of thoracolumbar myelopathy for Miniature Dachshunds.
- Published
- 2008
22. Conditioning of Karyoplasts for Producing Somatic Nuclear Transferred Gonadal Germ Cells in Domestic Chickens
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Takeshi Aikawa, Yusaku Kohara, Atsushi Tajima, Takeo Minematsu, and Yukio Kanai
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Cytoplasm ,Nuclear Transfer Techniques ,medicine.medical_specialty ,Somatic cell ,Centrifugation ,Chick Embryo ,Biology ,Culture Media, Serum-Free ,Cryopreservation ,Electrofusion ,Andrology ,chemistry.chemical_compound ,Internal medicine ,medicine ,Animals ,Germ ,Cytochalasin ,Cell Nucleus ,Fibroblasts ,Chick embryos ,Serum starvation ,Germ Cells ,Endocrinology ,chemistry ,Conditioning ,Female ,Animal Science and Zoology ,Chickens - Abstract
The objective of this study was to establish a protocol for generating karyoplasts that can be used to produce somatic nuclear transferred gonadal germ cells (snt-GGCs) in domestic chickens. Karyoplasts were produced by centrifuging cultured fibroblasts from 10-day-old chick embryos at 10,000 x g in the presence of 1.0 microg/ml cytochalasin B. The number of karyoplasts was significantly (P0.05) higher and the diameters of the karyoplasts were significantly (P0.05) smaller when fibroblasts were centrifuged for 60 min than for 10 or 30 min. It was possible to generate snt-GGCs by electrofusion of GGCs with karyoplasts produced from cryopreserved or serum-starved fibroblasts. These results indicate that karyoplasts generated from 10-day-old chick embryos can be used to produce snt-GGCs even after cryopreservation and serum starvation of the fibroblasts.
- Published
- 2008
23. Vertebral Stabilization Using Positively Threaded Profile Pins and Polymethylmethacrylate, with or Without Laminectomy, for Spinal Canal Stenosis and Vertebral Instability Caused by Congenital Thoracic Vertebral Anomalies
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Nicholas J.H. Sharp, Karen R. Muñana, Shinichi Kanazono, Yuki Yoshigae, and Takeshi Aikawa
- Subjects
Male ,medicine.medical_specialty ,medicine.medical_treatment ,Constriction, Pathologic ,Spinal canal stenosis ,Bone Nails ,Neurosurgical Procedures ,Spinal Cord Diseases ,Thoracic Vertebrae ,Dogs ,Spinal cord compression ,Surveys and Questionnaires ,Animals ,Medicine ,Spinal canal ,Dog Diseases ,Spinal cord injury ,Retrospective Studies ,General Veterinary ,medicine.diagnostic_test ,business.industry ,Laminectomy ,Decompression, Surgical ,medicine.disease ,Surgery ,Spinal Fusion ,Treatment Outcome ,medicine.anatomical_structure ,Spinal fusion ,Thoracic vertebrae ,Quality of Life ,Female ,Radiology ,business ,Spinal Canal ,Myelography - Abstract
Objective— To describe diagnostic findings, surgical technique, and outcome in dogs with thoracic spinal canal stenosis and vertebral instability secondary to congenital vertebral anomalies. Study Design— Retrospective clinical study. Animals— Dogs (n=9) with thoracic spinal canal stenosis. Methods— Medical records (1995–1996; 2000–2006) of 9 dogs with a myelographic diagnosis of spinal canal stenosis and/or vertebral instability secondary to congenital vertebral anomaly that were surgically managed by vertebral stabilization with or without laminectomy were reviewed. Data on pre- and postoperative neurologic status, diagnostic findings, surgical techniques, and outcomes were retrieved. Follow-up evaluations were performed at 1, 2, and 6 months. Long-term outcome was assessed by means of clinical examination or owner telephone interviews. Results— Spinal cord compression was confirmed by myelography, and in 2 dogs, dynamic compression by stress myelography. Eight dogs regained the ability to ambulate postoperatively. One dog with a partial recovery regained voluntary movement but did not become ambulatory. Conclusions— Spinal cord injury secondary to congenital vertebral anomaly may have a good outcome when treated by vertebral stabilization with or without laminectomy. Adequate stabilization of the vertebrae and improved neurologic outcome were achieved in most dogs. Clinical Relevance— Vertebral stabilization using positively threaded profile pins and polymethylmethacrylate with or without laminectomy is an effective treatment for spinal canal stenosis and vertebral instability secondary to congenital thoracic vertebral anomalies.
- Published
- 2007
24. Enhancement of Runx2 expression is potentially linked to β-catenin accumulation in canine intervertebral disc degeneration
- Author
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Munetaka, Iwata, Takeshi, Aikawa, Takaharu, Hakozaki, Kiyotaka, Arai, Hiroki, Ochi, Hirotaka, Haro, Masahiro, Tagawa, Yoshinori, Asou, and Yasushi, Hara
- Subjects
Male ,Extracellular Matrix Proteins ,Sulfonamides ,Calcinosis ,Gene Expression ,Core Binding Factor Alpha 1 Subunit ,Intervertebral Disc Degeneration ,Wnt Proteins ,Dogs ,Matrix Metalloproteinase 13 ,Animals ,RNA, Messenger ,Intervertebral Disc ,Lithium Chloride ,Wnt Signaling Pathway ,Cells, Cultured ,beta Catenin - Abstract
Intervertebral disc degeneration (IVDD) greatly affects the quality of life. The nucleus pulposus (NP) of chondrodystrophic dog breeds (CDBs) is similar to the human NP because the cells disappear with age and are replaced by fibrochondrocyte-like cells. Because IVDD develops as early as within the first year of life, we used canines as a model to investigate the in vitro mechanisms underlying IVDD. The mechanism underlying age-related IVDD, however, is poorly understood. Several research groups have suggested that Wnt/β-catenin signaling plays an important role in IVDD. However, the role of Wnt/β-catenin signals in IVD cells is not yet well understood. Here, we demonstrate that Wnt/β-catenin signaling could enhance Runx2 expression in IVDD and lead to IVD calcification. Nucleus pulposus (NP) tissue was obtained from Beagle dogs after evaluation of the degeneration based on magnetic resonance imaging (MRI). Histological analysis showed that lack of Safranin-O staining, calcified area, and matrix metalloproteinase (MMP) 13-positive cells increased with progression of the degeneration. Furthermore, the levels of β-catenin- and Runx2-positive cells also increased. Real-time reverse-transcription polymerase chain reaction analysis showed that the MRI signal intensity and mRNA expression levels of β-catenin and Runx2 are correlated in NP tissues. Moreover, supplementation of LiCl induced β-catenin accumulation and Runx2 expression. In contrast, FH535 inhibited LiCl-induced upregulation. These results suggest that Runx2 transcript and protein expression, potentially in combination with β-catenin accumulation, are enhanced in degenerated and calcified intervertebral discs of CDBs.
- Published
- 2014
25. Ganglion cyst arising from the composite occipito-atlanto-axial joint cavity in a cat
- Author
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M. Shibata, Shigeo Sadahiro, Masaaki Nishimura, Yuta Miyazaki, and Takeshi Aikawa
- Subjects
Ganglion Cysts ,General Veterinary ,business.industry ,Atlanto-axial joint ,Occipital bone ,Anatomy ,medicine.disease ,Cat Diseases ,Lesion ,Ganglion cyst ,Myelopathy ,medicine.anatomical_structure ,Atlanto-Occipital Joint ,Atlanto-Axial Joint ,Spinal cord compression ,medicine ,Cats ,Animals ,Animal Science and Zoology ,Spinal canal ,Cyst ,Female ,medicine.symptom ,business - Abstract
SummaryA four-year-old, female spayed Domestic Longhaired cat was referred for evaluation with a two month history of initial inability to jump progressing to ambulatory tetraparesis. Magnetic resonance imaging studies demonstrated a cystic lesion arising from the composite occipito-atlanto-axial joint cavity and extending to the region of the occipital bone and the axis. The lesion surrounded the spinal canal, causing moderate dorsal spinal cord compression at the atlanto-occipital joint. A dynamic myelographic study demonstrated attenuation of the dorsal contrast column at the atlanto-occipital joint when the cervical spine was positioned in extension. Partial excision of the cyst capsule by a ventral approach resulted in long-term (64 months) resolution of clinical signs. Histological evaluation was consistent with a ganglion cyst. An intra-spinal ganglion cyst arising from the composite occipito-atlanto-axial joint cavity may be considered as an uncommon differential diagnosis for cats with cervical myelopathy.
- Published
- 2013
26. Long-term neurologic outcome of hemilaminectomy and disk fenestration for treatment of dogs with thoracolumbar intervertebral disk herniation: 831 cases (2000-2007)
- Author
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Hiroshi Fujita, Mitsuhiro Shibata, Takeshi Aikawa, Yuki Yoshigae, and Shinichi Kanazono
- Subjects
Male ,medicine.medical_specialty ,General Veterinary ,business.industry ,Urinary system ,Incidence (epidemiology) ,Laminectomy ,Urinary incontinence ,medicine.disease ,Surgery ,Intervertebral disk ,Dogs ,Treatment Outcome ,Concomitant ,medicine ,Fecal incontinence ,Animals ,Hernia ,Female ,Dog Diseases ,medicine.symptom ,business ,Fenestration ,Intervertebral Disc Displacement ,Retrospective Studies - Abstract
Objective—To determine the proportion of dogs with thoracolumbar intervertebral disk herniation (IVDH) that successfully recovered following hemilaminectomy and fenestration, the time to ambulation (TTA) in affected dogs after surgery, and the frequency of urinary and fecal incontinence in recovered dogs and to document long-term complications. Design—Retrospective case series. Animals—831 dogs with thoracolumbar IVDH treated by hemilaminectomy and concomitant disk fenestration by the same surgeon. Procedures—For all dogs, neurologic deficits before surgery had been assessed with a modified grading system. Dogs were reexamined after surgery over a period of 3 to 6 months, and follow-up evaluation was performed at > 12 months. The proportion of dogs that neurologically improved after surgery, TTA, and incidence of fecal or urinary incontinence in recovered dogs were compared among dogs with various grades of neurologic dysfunction before surgery. Results—Of 831 dogs, 122 had unsuccessful outcomes and 709 had successful outcomes. Of 620 dogs with intact deep nociception before surgery, 606 (97.7%) were ambulatory after surgery. Despite maintaining the ability to walk, 7 dogs were judged to have an unsuccessful outcome because the severity of ataxia did not improve. Of 211 paraplegic dogs with loss of deep nociception, 110 (52.1%) dogs became ambulatory after surgery. Long-term complications included incontinence, permanent neurologic deterioration, and self-mutilation. Dogs with paraplegia before surgery had a higher frequency of urinary or fecal incontinence, compared with dogs that were ambulatory. Conclusions and Clinical Relevance—Prognosis for dogs with thoracolumbar IVDH that retain deep nociception in at least 1 of the pelvic limbs or tail before surgery was good.
- Published
- 2012
27. Recurrent thoracolumbar intervertebral disc extrusion after hemilaminectomy and concomitant prophylactic fenestration in 662 chondrodystrophic dogs
- Author
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Takeshi, Aikawa, Hiroshi, Fujita, Mitsuhiro, Shibata, and Taishi, Takahashi
- Subjects
Male ,Dogs ,Recurrence ,Laminectomy ,Animals ,Female ,Dog Diseases ,Osteochondrodysplasias ,Magnetic Resonance Imaging ,Intervertebral Disc Displacement ,Retrospective Studies - Abstract
To determine the prevalence and location of recurrent thoracolumbar intervertebral disc extrusion (T-L IVDE) after hemilaminectomy with prophylactic fenestration (PF) and to document PF-related complications.Retrospective case series.Chondrodystrophic dogs (n = 793).In 662 successfully recovered dogs (1 year follow-up), the prevalence of dogs with recurrent T-L IVDE that required a 2nd surgery and dogs with clinical signs that improved without surgery was evaluated. Prevalence of second disc extrusions (SDEs) within T11-L4 intervertebral discs was compared between PF discs and non-PF discs.T-L SDEs were intraoperatively confirmed in 15 dogs (2.3%), 2-61 months after initial surgery and 66 dogs (10.0%) had signs of T-L IVDE recurrence that improved without surgery (mean follow-up, 44.7 months). No dog had further extrusion at the initial T-L site. SDE occurred at a PF disc (n = 1), adjacent to PF discs (8), or at distant discs (6). Prevalence of SDE in non-PF discs was 26.2 times higher than PF discs (95% CI: 3.4, 203.4; P.001). Major PF-related complications included iatrogenic introduction of the disc material into the spinal canal (n = 1), and vertebral subluxation/instability (3) at 1-88 months postoperatively.SDE is more likely to occur at non-PF discs than PF discs when PF is performed at spaces predisposed to disc extrusion. PF is a safe and effective treatment to prevent SDE in chondrodystrophic dogs.
- Published
- 2012
28. Recurrent Thoracolumbar Intervertebral Disc Extrusion after Hemilaminectomy and Concomitant Prophylactic Fenestration in 662 Chondrodystrophic Dogs
- Author
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Mitsuhiro Shibata, Takeshi Aikawa, Hiroshi Fujita, and Taishi Takahashi
- Subjects
medicine.medical_specialty ,medicine.anatomical_structure ,General Veterinary ,business.industry ,Concomitant ,medicine ,Effective treatment ,Spinal canal ,Fenestration ,business ,Intervertebral disc extrusion ,Vertebral subluxation ,Surgery - Abstract
Objectives To determine the prevalence and location of recurrent thoracolumbar intervertebral disc extrusion (T-L IVDE) after hemilaminectomy with prophylactic fenestration (PF) and to document PF-related complications. Study Design Retrospective case series. Sample population Chondrodystrophic dogs (n = 793). Methods In 662 successfully recovered dogs (>1 year follow-up), the prevalence of dogs with recurrent T-L IVDE that required a 2nd surgery and dogs with clinical signs that improved without surgery was evaluated. Prevalence of second disc extrusions (SDEs) within T11-L4 intervertebral discs was compared between PF discs and non-PF discs. Results T-L SDEs were intraoperatively confirmed in 15 dogs (2.3%), 2–61 months after initial surgery and 66 dogs (10.0%) had signs of T-L IVDE recurrence that improved without surgery (mean follow-up, 44.7 months). No dog had further extrusion at the initial T-L site. SDE occurred at a PF disc (n = 1), adjacent to PF discs (8), or at distant discs (6). Prevalence of SDE in non-PF discs was 26.2 times higher than PF discs (95% CI: 3.4, 203.4; P < .001). Major PF-related complications included iatrogenic introduction of the disc material into the spinal canal (n = 1), and vertebral subluxation/instability (3) at 1–88 months postoperatively. Conclusion SDE is more likely to occur at non-PF discs than PF discs when PF is performed at spaces predisposed to disc extrusion. PF is a safe and effective treatment to prevent SDE in chondrodystrophic dogs.
- Published
- 2012
29. A comparison of thoracolumbar intervertebral disc extrusion in French Bulldogs and Dachshunds and association with congenital vertebral anomalies
- Author
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Takeshi, Aikawa, Mitsuhiro, Shibata, Moe, Asano, Yasushi, Hara, Masahiro, Tagawa, and Hiromitsu, Orima
- Subjects
Male ,Dogs ,Lumbar Vertebrae ,Animals ,Female ,Genetic Predisposition to Disease ,Dog Diseases ,Intervertebral Disc Degeneration ,Thoracic Vertebrae ,Retrospective Studies - Abstract
To compare data for French Bulldogs and Dachshunds that had hemilaminectomy for thoracolumbar intervertebral disc extrusion (T-L IVDE) by 1 surgeon and to evaluate the association between IVDE and congenital vertebral anomalies.Retrospective case series.French Bulldogs (n = 47) and 671 Dachshunds.Age, gender, vertebral anomaly, kyphosis/kyphoscoliosis, IVDE site, non-recovery and progressive hemorrhagic myelomalacia development from grade 5 (paraplegia without deep nociception) were compared between the 2 breeds.French Bulldogs were significantly younger (P = .00001), more likely to be male (P = .023), and more likely to have a congenital vertebral anomaly and kyphosis/kyphoscoliosis (P.00001) than Dachshunds. The frequencies of French Bulldogs with IVDE within typical sites (T11-L3) were significantly lower (P = .0005) and within caudal sites (L3-L7) significantly higher (P = .0001) compared with Dachshunds. None of the French Bulldogs had IVDE within the kyphotic/kyphoscoliotic segment. The frequency of lumbar IVDE (L1-L5) in French Bulldogs with kyphosis/kyphoscoliosis was significantly higher (P = .003) compared with French Bulldogs without kyphosis/kyphoscoliosis. In grade 5 dogs, the risk of developing progressive hemorrhagic myelomalacia in French Bulldogs was significantly higher (P = .03) than in Dachshunds.The distribution of IVDE site in French Bulldogs within the thoracolumbar and lumbar spine was different from Dachshunds. IVDE sites were not located at the sites of vertebral anomaly. French Bulldogs appeared to have T-L IVDE at younger ages, with higher male predisposition and higher risk of developing progressive hemorrhagic myelomalacia from grade 5 compared with Dachshunds.
- Published
- 2011
30. Modified ventral stabilization using positively threaded profile pins and polymethylmethacrylate for atlantoaxial instability in 49 dogs
- Author
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Takeshi, Aikawa, Mitsuhiro, Shibata, and Hiroshi, Fujita
- Subjects
Joint Instability ,Dogs ,Treatment Outcome ,Atlanto-Axial Joint ,Joint Dislocations ,Animals ,Polymethyl Methacrylate ,Dog Diseases ,Bone Nails ,Retrospective Studies - Abstract
To describe diagnostic findings, complications, and long-term outcome of dogs with atlantoaxial instability (AAI) that had modified ventral stabilization with positively threaded profile pins and polymethylmethacrylate by 1 surgeon and to evaluate the potential prognostic indicators.Retrospective case series.Dogs (n = 49) with AAI.Medical records (2000-2010) of dogs with AAI that had modified ventral stabilization were reviewed. Data on pre- and postoperative neurologic status, diagnostic findings, and outcomes were retrieved. Age, neurologic grade, duration of clinical abnormalities, dens abnormalities, and MRI findings were evaluated as the potential predictors for recovery. Age and cancellous bone grafting were evaluated as the potential predictors of postoperative pin breakage.Two dogs died during the perioperative period. In 47 dogs with follow up (median: 29 months; range, 4-110 months), 46 dogs (94%) improved neurologically after surgery, but 1 dog did not become ambulatory. There were no long term complications that resulted in serious neurologic deterioration or that required additional surgery. Partial pin breakage (1-5 pins) occurred in 16 dogs at 1-27.5 months (median, 5 months) without neurologic deterioration. Only the nonambulatory preoperative grade was significantly (P = .002) associated with non/incomplete recovery compared with ambulatory dogs.Adequate stabilization of the vertebrae and improved neurologic status were achieved in most dogs with AAI using a modified ventral stabilization technique with positively threaded profile pins and polymethylmethacrylate.
- Published
- 2010
31. Unilateral hydronephrosis and partial ureteral obstruction by entrapment in a granuloma in a spayed dog
- Author
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Takeshi Aikawa, Yuki Yoshigae, and Shinichi Kanazono
- Subjects
medicine.medical_specialty ,Ovariectomy ,Urology ,Renal function ,Hydronephrosis ,Anastomosis ,urologic and male genital diseases ,Hysterectomy ,Entrapment ,Dogs ,Suture (anatomy) ,medicine ,Animals ,Dog Diseases ,Small Animals ,Granuloma ,Spayed dog ,urogenital system ,business.industry ,Anastomosis, Surgical ,medicine.disease ,female genital diseases and pregnancy complications ,Surgery ,Treatment Outcome ,Female ,Azotemia ,business ,Ureteral Obstruction - Abstract
A 6-year-old, spayed female dog had hydronephrosis and incomplete ureteral occlusion on the left side. An end-to-side ureteral anastomosis was performed. The incomplete ureteral occlusion was determined to be related to an ovarian pedicle granuloma formation and was presumably related to a reaction to the suture material used for ovariohysterectomy (OVH) performed 5 years prior to presentation. Azotemia and hydronephrosis were dramatically improved after surgery, and renal function has been well maintained for 3 years. To the authors’ knowledge, a chronic partial ureteral occlusion associated with an ovarian pedicle granuloma from an OVH has not been reported.
- Published
- 2009
32. Twin-register architecture for an AI processor
- Author
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Kenichi Maeda, Tsukasa Matoba, Mitsuo Saito, Okamura Mitsuyoshi, Takeshi Aikawa, Takeshi Takamiya, and Kenji Minagawa
- Subjects
Cellular architecture ,Processor register ,Computer science ,computer.software_genre ,Transport triggered architecture ,Execution time ,Stack register ,Prolog ,Computer architecture ,Artificial Intelligence ,Control and Systems Engineering ,Operating system ,Electrical and Electronic Engineering ,Architecture ,Space-based architecture ,Hardware_REGISTER-TRANSFER-LEVELIMPLEMENTATION ,computer ,Dataflow architecture ,computer.programming_language - Abstract
We have developed a twin-register architecture to improve the backtracking speed of Prolog programs. The twin-register architecture is designed to realize a virtual infinite register set. The features of the architecture are: (1) only a small amount of hardware is needed including a pair of register-files; and, (2) data transfer between the register and the memory is automatically executed. A register saving/restoring operation and the Prolog instruction are executed in parallel in order to reduce the overhead of memory accesses. We have implemented the twin-register architecture into our AI processor IP704 to show its effectiveness. Experimental results have shown that the execution time of 8-Queen program is reduced by 15% in the case of the twin-register architecture, as compared with that in the case of the ordinary architecture in which saving/restoring are done by software. Also, we have found the architecture is useful for register saving/restoring of the procedure CALL/RETURN in general procedural programs.
- Published
- 1990
33. 2404 Driving assistant system for traffic accident prevention before anything happens : Application in some situations
- Author
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Hiroki Seto, Satoru Takenaka, Takeshi Aikawa, Yosuke Tate, Haruhiko Nakatsuji, and Yukiyo Kuriyagawa
- Subjects
Transport engineering ,Computer science ,Traffic accident ,Computer security ,computer.software_genre ,computer - Published
- 2015
34. Development and Application of the Total Risk Assessment Tool by Effective Feedbacks for Preventing Anormalies (PSAM-0239)
- Author
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Mitsuhiro Ebisu, Kenichi Takano, Takeshi Aikawa, Kenichi Hayase, and Akihiko Nagasaka
- Subjects
Total risk ,Engineering ,business.industry ,Environmental resource management ,business ,Socioeconomic status - Abstract
Mitsuhiro Ebisu / HFC, Socioeconomic Research Institute, CRIEPI, 2-11-1, Komaeshi, Tokyo, 201-8511 Japan, ebisu@criepi.denken.or.jp Kenichi Takano / HFC, Socioeconomic Research Institute, CRIEPI, 2-11-1, Komaeshi, Tokyo, 201-8511 Japan, takano@criepi.denken.or.jp Kenichi Hayase / HFC, Socioeconomic Research Institute, CRIEPI, 2-11-1, Komaeshi, Tokyo, 201-8511 Japan, hayase@criepi.denken.or.jp PSAM-0239 Proceedings of the 8th International Conference on Probabilistic Safety Assessment and Management May 14-18, 2006, New Orleans, Louisiana, USA
- Published
- 2006
35. Choice Effect Suppressed Distance Effect in number comparison task in brain activity
- Author
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Takahiro Horaguchi, Takeshi Aikawa, Yousuke Ogata, Miyuki Yamamoto, and Noriya Watanabe
- Subjects
Brain activity and meditation ,General Neuroscience ,General Medicine ,Distance effect ,Psychology ,Developmental psychology ,Task (project management) ,Cognitive psychology - Published
- 2009
36. The influence of choice and interstimulus interval in number comparison task
- Author
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Takahiro Horaguchi, Yousuke Ogata, Miyuki Yamamoto, and Takeshi Aikawa
- Subjects
medicine.medical_specialty ,General Neuroscience ,Interstimulus interval ,medicine ,General Medicine ,Audiology ,Mathematics ,Task (project management) - Published
- 2009
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