Search

Your search keyword '"T Toll"' showing total 55 results
Start Over Author "T Toll" Language undetermined
55 results on '"T Toll"'

2. The Case for an EIC Theory Alliance

Author

R Abir, I Akushevich, T Altinoluk, D Anderle, B Balantekin, J Barata, M Battaglieri, C Bertulani, G Beuf, C Bissolotti, D Boer, M Boglione, R Boughezal, E Braaten, N Brambilla, V Braun, D Byer, F Celiberto, Y Chien, I Cloet, M Constantinou, W Cosyn, A Courtoy, A Czajka, U D'Alesio, I Danilkin, D Das, D de Florian, A Delgado, W Detmold, M Doring, A Dumitru, M Echevarria, R Edwards, G Eichmann, B El-Bennich, M Engelhardt, C Fernandez-Ramirez, C Fischer, G Fox, L Gamberg, M Garzelli, F Giacosa, G da Silveira, D Glazier, V Goncalves, S Grossberndt, F Guo, R Gupta, Y Hatta, M Hentschinski, A Blin, T Hobbs, A Ilyichev, J Jalilian-Marian, S Jia, Z Kang, B Karki, W Ke, V Khachatryan, D Kharzeev, S Klein, V Korepin, Y Kovchegov, S Kumano, W Lai, R Lebed, C Lee, K Lee, J Liao, H Lin, K Liu, S Liuti, C Lorce, H Mantysaari, V Mathieu, N Mathur, Y Mehtar-Tani, W Melnitchouk, E Mereghetti, A Metz, G Miller, S Mukherjee, S Munier, F Murgia, P Nadolsky, J Negele, D Neill, J Nemchik, E Nocera, V Okorokov, F Olness, B Pasquini, C Peng, P Petreczky, F Petriello, A Pilloni, B Pire, C Pisano, D Pitonyak, M Praszalowicz, A Prokudin, J Qiu, M Radici, J Rittenhouse West, A Rodas, S Rodini, J Rojo, F Salazar, E Santopinto, M Sargsian, N Sato, B Schenke, S Schindler, G Schnell, I Scimemi, J Segovia, K Semonov-Tian-Shansky, P Shanahan, D Shao, M Sievert, A Signori, R Singh, V Skokov, Q Song, S Srednyak, I Stewart, R Sufian, E Swanson, S Syritsyn, A Szczepaniak, Y Tawabutr, J Terry, T Toll, O Tomalak, F Twagirayezu, R Venugopalan, I Vitev, A Vladimirov, W Vogelsang, R Vogt, G Vujanovic, W Waalewijn, X Wang, B Xiao, Y Yang, X Yao, F Yuan, Y Zhao, and P Zurita

Published
2023

3. An Electroencephalography Connectomic Profile of Posttraumatic Stress Disorder

Author

Kamron Sarhadi, Duna Abu-Amara, Russell T. Toll, Amit Etkin, Manjari Narayan, Kasra Sarhadi, Yu Zhang, Rachael Wright, Emmanuel Shpigel, Carena A. Cornelssen, Charles R. Marmar, Roland Hart, Carlo de los Angeles, Nicole Anicetti, Wei Wu, Parker Longwell, Sharon Naparstek, Bryan Gonzalez, Brian Patenaude, Silas Mann, and Jennifer Newman

Subjects
Adult, Male, Electroencephalography, Stress Disorders, Post-Traumatic, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Power envelope, Neuroimaging, Connectome, medicine, Humans, Veterans, medicine.diagnostic_test, Functional connectivity, Brain, Cognition, 030227 psychiatry, Psychiatry and Mental health, Posttraumatic stress, Case-Control Studies, Female, Nerve Net, Psychology, Neuroscience, 030217 neurology & neurosurgery
Abstract

The authors sought to identify brain regions whose frequency-specific, orthogonalized resting-state EEG power envelope connectivity differs between combat veterans with posttraumatic stress disorder (PTSD) and healthy combat-exposed veterans, and to determine the behavioral correlates of connectomic differences.The authors first conducted a connectivity method validation study in healthy control subjects (N=36). They then conducted a two-site case-control study of veterans with and without PTSD who were deployed to Iraq and/or Afghanistan. Healthy individuals (N=95) and those meeting full or subthreshold criteria for PTSD (N=106) underwent 64-channel resting EEG (eyes open and closed), which was then source-localized and orthogonalized to mitigate effects of volume conduction. Correlation coefficients between band-limited source-space power envelopes of different regions of interest were then calculated and corrected for multiple comparisons. Post hoc correlations of connectomic abnormalities with clinical features and performance on cognitive tasks were conducted to investigate the relevance of the dysconnectivity findings.Seventy-four brain region connections were significantly reduced in PTSD (all in the eyes-open condition and predominantly using the theta carrier frequency). Underconnectivity of the orbital and anterior middle frontal gyri were most prominent. Performance differences in the digit span task mapped onto connectivity between 25 of the 74 brain region pairs, including within-network connections in the dorsal attention, frontoparietal control, and ventral attention networks.Robust PTSD-related abnormalities were evident in theta-band source-space orthogonalized power envelope connectivity, which furthermore related to cognitive deficits in these patients. These findings establish a clinically relevant connectomic profile of PTSD using a tool that facilitates the lower-cost clinical translation of network connectivity research.

Published
2020

5. Functional connectivity using high density EEG shows competitive reliability and agreement across test/retest sessions

Author

Noriah Johnson, Russell T. Toll, Michelle L. Eisenberg, Amit Etkin, Mallissa Waats, Camarin E. Rolle, Manjari Narayan, Trevor Caudle, Marvin Yan, Dawlat El-Said, and Wei Wu

Subjects
Brain Mapping, Computer science, General Neuroscience, Functional connectivity, Rest, Brain, Reproducibility of Results, Electroencephalography, High density eeg, Magnetic Resonance Imaging, Reliability engineering, Test (assessment), Electrophysiological Phenomena, Humans, Reliability (statistics)
Abstract

Electrophysiological resting state functional connectivity using high density electroencephalography (hdEEG) is gaining momentum. The increased resolution offered by hdEEG, usually either 128 or 256 channels, permits source localization of EEG signals on the cortical surface. However, the number of methodological options for the acquisition and analysis of resting state hdEEG is extremely large. These include acquisition duration, eyes open/closed, channel density, source localization methods, and functional connectivity metric.We undertake an extensive examination of the test-retest reliability and methodological agreement of all these options for regional measures of functional connectivity.Power envelope connectivity shows larger test-retest reliability than imaginary coherence across all bands. While channel density doesn't strongly impact reliability or agreement, source localization methods produce systematically different functional connectivity, highlighting an important obstacle for replicating results in the literature. Most importantly, reliability and agreement often plateaus at or after 6 minutes of acquisition, well beyond the typical duration of 3 minutes. Finally, our study demonstrates that resting EEG can be as or more reliable than resting fMRI acquired in the same individuals.The competitive reliability and agreement of power envelope connectivity greatly increases our confidence in measuring resting state connectivity using EEG and its capacity to find individual differences.

Published
2021

6. EEG functional connectivity analysis in the source space

Author

Wanze Xie, Russell T. Toll, and Charles A. Nelson

Subjects
Brain Mapping, Cognitive Neuroscience, Brain, Humans, Electroencephalography, Child, Magnetic Resonance Imaging
Abstract

There is a growing interest in using electroencephalography (EEG) and source modeling to investigate functional interactions among cortical processes, particularly when dealing with pediatric populations. This paper introduces two pipelines that have been recently used to conduct EEG FC analysis in the cortical source space. The analytic streams of these pipelines can be summarized into the following steps: 1) cortical source reconstruction of high-density EEG data using realistic magnetic resonance imaging (MRI) models created with age-appropriate MRI templates; 2) segmentation of reconstructed source activities into brain regions of interest; and 3) estimation of FC in age-related frequency bands using robust EEG FC measures, such as weighted phase lag index and orthogonalized power envelope correlation. In this paper we demonstrate the two pipelines with resting-state EEG data collected from children at 12 and 36 months of age. We also discuss the advantages and limitations of the methods/techniques integrated into the pipelines. Given there is a need in the research community for open-access analytic toolkits that can be used for pediatric EEG data, programs and codes used for the current analysis are made available to the public.

Published
2021

7. Mapping causal circuit dynamics in stroke using simultaneous electroencephalography and transcranial magnetic stimulation

Author

Fiona M. Baumer, Hersh M. Trivedi, Wei Wu, Joshua T. Jordan, Marion S. Buckwalter, Ketura Berry, Amit Etkin, Russell T. Toll, Maarten G Lansberg, Madelleine Garcia, Camarin E. Rolle, and Karen Monusko

Subjects
Male, Aging, Neurology, medicine.medical_treatment, Electroencephalography, 0302 clinical medicine, 80 and over, 2.1 Biological and endogenous factors, Aetiology, Stroke, Aged, 80 and over, Brain Mapping, Connectivity, Assistive Technology, Rehabilitation, medicine.diagnostic_test, 05 social sciences, Motor Cortex, General Medicine, Middle Aged, Transcranial Magnetic Stimulation, Paresis, medicine.anatomical_structure, Neurological, Female, Cognitive Sciences, Motor cortex, Adult, medicine.medical_specialty, TMS-EEG, 1.1 Normal biological development and functioning, Bioengineering, 050105 experimental psychology, 03 medical and health sciences, Physical medicine and rehabilitation, Arm function, Clinical Research, Underpinning research, medicine, Humans, 0501 psychology and cognitive sciences, Neurochemistry, RC346-429, Aged, Neurology & Neurosurgery, business.industry, Research, Neurosciences, Beta, medicine.disease, Brain Disorders, Transcranial magnetic stimulation, Physical Rehabilitation, Case-Control Studies, wPLI, Neurology. Diseases of the nervous system, Neurology (clinical), business, 030217 neurology & neurosurgery
Abstract

Background Motor impairment after stroke is due not only to direct tissue loss but also to disrupted connectivity within the motor network. Mixed results from studies attempting to enhance motor recovery with Transcranial Magnetic Stimulation (TMS) highlight the need for a better understanding of both connectivity after stroke and the impact of TMS on this connectivity. This study used TMS-EEG to map the causal information flow in the motor network of healthy adult subjects and define how stroke alters these circuits. Methods Fourteen stroke patients and 12 controls received TMS to two sites (bilateral primary motor cortices) during two motor tasks (paretic/dominant hand movement vs. rest) while EEG measured the cortical response to TMS pulses. TMS-EEG based connectivity measurements were derived for each hemisphere and the change in connectivity (ΔC) between the two motor tasks was calculated. We analyzed if ΔC for each hemisphere differed between the stroke and control groups or across TMS sites, and whether ΔC correlated with arm function in stroke patients. Results Right hand movement increased connectivity in the left compared to the right hemisphere in controls, while hand movement did not significantly change connectivity in either hemisphere in stroke. Stroke patients with the largest increase in healthy hemisphere connectivity during paretic hand movement had the best arm function. Conclusions TMS-EEG measurements are sensitive to movement-induced changes in brain connectivity. These measurements may characterize clinically meaningful changes in circuit dynamics after stroke, thus providing specific targets for trials of TMS in post-stroke rehabilitation.

Published
2021

8. A Paradox in Polarization? Cross-pressured Representatives and the Missing Incentive to Moderate

Author

Benjamin T. Toll

Subjects
Microeconomics, Incentive, 0502 economics and business, 05 social sciences, Polarization (politics), 050602 political science & public administration, Economics, General Social Sciences, 050207 economics, 0506 political science
Abstract

Members of the public are often left choosing between two extreme candidates who will not represent the moderate, aggregate, public effectively. Cross-pressured members of the U.S. Congress serve a constituency that votes for the opposite party at the national level. If there is any group of representatives that have an incentive to moderate their voting behavior, it is cross-pressured members. In this article, I show that cross-pressured members are more moderate than the average member of their party. This could provide constraints on rampant partisanship in the form of districts that are comfortable electing a representative of one party and voting for the president of the other. However, I show that these members are significantly less likely to be reelected. Thus a paradox exists in which cross-pressured members who moderate their voting behavior are no more likely to be rewarded for behaving the way citizens claim they want to represent.

Published
2019

12. Cortical Connectivity Moderators of Antidepressant vs Placebo Treatment Response in Major Depressive Disorder: Secondary Analysis of a Randomized Clinical Trial

Author

Manish K. Jha, Maurizio Fava, Madhukar H. Trivedi, Joseph M. Trombello, Camarin E. Rolle, Crystal Cooper, Amit Etkin, Gregory A. Fonzo, Cherise Chin-Fatt, Russell T. Toll, Thilo Deckersbach, Myrna M. Weissman, Diego A. Pizzagalli, and Wei Wu

Subjects
Adult, Male, medicine.medical_specialty, Adolescent, Placebo, law.invention, 03 medical and health sciences, Young Adult, 0302 clinical medicine, Randomized controlled trial, law, Internal medicine, Sertraline, Medicine, Gamma Rhythm, Humans, Aged, Psychiatric Status Rating Scales, Depressive Disorder, Major, business.industry, Hamilton Rating Scale for Depression, Anhedonia, Brain, Electroencephalography, Middle Aged, medicine.disease, 030227 psychiatry, Clinical trial, Psychiatry and Mental health, Alpha Rhythm, Linear Models, Antidepressant, Major depressive disorder, Female, medicine.symptom, business, 030217 neurology & neurosurgery, Selective Serotonin Reuptake Inhibitors, medicine.drug
Abstract

Importance Despite the widespread awareness of functional magnetic resonance imaging findings suggesting a role for cortical connectivity networks in treatment selection for major depressive disorder, its clinical utility remains limited. Recent methodological advances have revealed functional magnetic resonance imaging–like connectivity networks using electroencephalography (EEG), a tool more easily implemented in clinical practice. Objective To determine whether EEG connectivity could reveal neural moderators of antidepressant treatment. Design, Setting, and Participants In this nonprespecified secondary analysis, data were analyzed from the Establishing Moderators and Biosignatures of Antidepressant Response in Clinic Care study, a placebo-controlled, double-blinded randomized clinical trial. Recruitment began July 29, 2011, and was completed December 15, 2015. A random sample of 221 outpatients with depression aged 18 to 65 years who were not taking medication for depression was recruited and assessed at 4 clinical sites. Analysis was performed on an intent-to-treat basis. Statistical analysis was performed from November 16, 2018, to May 23, 2019. Interventions Patients received either the selective serotonin reuptake inhibitor sertraline hydrochloride or placebo for 8 weeks. Main Outcomes and Measures Electroencephalographic orthogonalized power envelope connectivity analyses were applied to resting-state EEG data. Intent-to-treat prediction linear mixed models were used to determine which pretreatment connectivity patterns were associated with response to sertraline vs placebo. The primary clinical outcome was the total score on the 17-item Hamilton Rating Scale for Depression, administered at each study visit. Results Of the participants recruited, 9 withdrew after first dose owing to reported adverse effects, and 221 participants (150 women; mean [SD] age, 37.8 [12.7] years) underwent EEG recordings and had high-quality pretreatment EEG data. After correction for multiple comparisons, connectome-wide analyses revealed moderation by connections within and between widespread cortical regions—most prominently parietal—for both the antidepressant and placebo groups. Greater alpha-band and lower gamma-band connectivity predicted better placebo outcomes and worse antidepressant outcomes. Lower connectivity levels in these moderating connections were associated with higher levels of anhedonia. Connectivity features that moderate treatment response differentially by treatment group were distinct from connectivity features that change from baseline to 1 week into treatment. The group mean (SD) score on the 17-item Hamilton Rating Scale for Depression was 18.35 (4.58) at baseline and 26.14 (30.37) across all time points. Conclusions and Relevance These findings establish the utility of EEG-based network functional connectivity analyses for differentiating between responses to an antidepressant vs placebo. A role emerged for parietal cortical regions in predicting placebo outcome. From a treatment perspective, capitalizing on the therapeutic components leading to placebo response differentially from antidepressant response should provide an alternative direction toward establishing a placebo signature in clinical trials, thereby enhancing the signal detection in randomized clinical trials. Trial Registration ClinicalTrials.gov identifier:NCT01407094

Published
2020

14. Comprehensive phenotyping of depression disease trajectory and risk: Rationale and design of Texas Resilience Against Depression study (T-RAD)

Author

Anne K. Fuller, Manish K. Jha, Andrew H. Czysz, Cherise Chin Fatt, Crystal Cooper, Abu Minhajuddin, Bharathi S. Gadad, Madhukar H. Trivedi, Brittany L. Mason, Jennifer L. Hughes, Joseph M. Trombello, Sangita Sethuram, Thomas J. Carmody, Taryn L. Mayes, Russell T. Toll, and Tracy L. Greer

Subjects
Adult, medicine.medical_specialty, Bipolar Disorder, Adolescent, Disease, 03 medical and health sciences, Young Adult, 0302 clinical medicine, medicine, Humans, Bipolar disorder, Prospective Studies, Psychiatry, Child, Biological Psychiatry, Depression (differential diagnoses), Disease burden, business.industry, Depression, Mood Disorders, medicine.disease, Texas, 030227 psychiatry, Psychiatry and Mental health, Mood, Major depressive disorder, Personalized medicine, business, 030217 neurology & neurosurgery, Companion diagnostic
Abstract

Depression has a chronic and recurrent course often with early onset and is the leading cause of disability worldwide. In contrast to diagnoses for other conditions which rely on precise medical tests, the diagnosis of depression still focuses exclusively on symptom reports. As a result, heterogeneous patient groups are included under broad categories. Furthermore, in the absence of companion diagnostic tests, choosing specific treatments for patients remains imprecise with only one-third of patients entering remission with initial treatment, with others requiring multiple intervention steps to achieve remission. In addition to improving treatment outcomes, disease prevention is essential to reduce overall disease burden. Adolescence is a critical window where complex emotional, social, familial, and biological shifts may predispose to lifelong depression. Thus, personalized medicine, integrating individual variability in genes, brain function, and clinical phenotypes, can offer a comprehensive approach to provide precise diagnosis, novel drug development, optimal treatment assignment, and prevention of illness and its associated burden. Texas Resilience Against Depression study (T-RAD) encompasses two natural history, longitudinal (10 + years), prospective studies (D2K and RAD), each enrolling 2500 participants. The D2K study follows participants (ages 10 years and older) who have a current or past diagnosis of depression or bipolar disorder. The RAD study follows participants aged 10–24 years who are at risk for depression but not yet suffering from the disease. The T-RAD study will help to uncover the socio-demographic, lifestyle, clinical, psychological, and neurobiological factors that contribute to mood disorder onset, recurrence, progression, and differential treatment response.

Published
2019

15. Using fMRI connectivity to define a treatment-resistant form of post-traumatic stress disorder

Author

Yevgeniya V. Zaiko, Duna Abu-Amara, Adi Maron-Katz, Russell T. Toll, Desmond J. Oathes, Brian Patenaude, Irene Akingbade, Jillian Autea, Emmanuel Shpigel, Roland Hart, Madeleine S. Goodkind, Elizabeth Weiss, Wei Wu, Raleigh Edelstein, Parker Longwell, Sanno E. Zack, Steven E. Lindley, Charles R. Marmar, Silas Mann, Edward T. Bullmore, Kathleen Durkin, Allison L. Thompson, Petra E. Vértes, Afia Genfi, Barbara O. Rothbaum, Jaime Ramos-Cejudo, Steven H. Baete, Jennifer Newman, Silvia Fossati, Gregory A. Fonzo, Kathy Peng, Nicolas Crossley, Jonas Richiardi, Fernando E. Boada, Bryan Gonzalez, Joachim Hallmayer, Corey J. Keller, Amit Etkin, Bruce A. Arnow, Ruth O'Hara, Jingyun Chen, Julia Huemer, Etkin, Amit [0000-0001-8259-3521], Maron-Katz, Adi [0000-0003-4246-1748], Wu, Wei [0000-0003-1901-9134], Huemer, Julia [0000-0003-1942-763X], Vértes, Petra E [0000-0002-0992-3210], Richiardi, Jonas [0000-0002-6975-5634], Keller, Corey J [0000-0003-0529-3490], Ramos-Cejudo, Jaime [0000-0002-0993-9909], Zaiko, Yevgeniya V [0000-0003-0151-5455], Longwell, Parker [0000-0001-8344-1685], Toll, Russ T [0000-0002-7655-6668], Thompson, Allison [0000-0003-3937-0327], Edelstein, Raleigh [0000-0003-2415-3610], Akingbade, Irene [0000-0002-1071-327X], Mann, Silas [0000-0003-3152-5208], Baete, Steven H [0000-0003-3361-3789], Boada, Fernando E [0000-0002-3289-9917], Newman, Jennifer [0000-0002-5526-9600], Oathes, Desmond J [0000-0001-7346-2669], Lindley, Steven E [0000-0003-0051-8224], Abu-Amara, Duna [0000-0003-2050-3484], Arnow, Bruce A [0000-0003-1645-857X], Crossley, Nicolas [0000-0002-3060-656X], Hallmayer, Joachim [0000-0002-8520-4939], Fossati, Silvia [0000-0002-2047-222X], Bullmore, Edward T [0000-0002-8955-8283], O'Hara, Ruth [0000-0001-6583-4995], and Apollo - University of Cambridge Repository

Subjects
medicine.medical_treatment, Rest, Comorbidity, Electroencephalography, Basic Behavioral and Social Science, Medical and Health Sciences, Brain mapping, Article, Stress Disorders, Post-Traumatic, 03 medical and health sciences, 0302 clinical medicine, Neuroimaging, Clinical Research, Behavioral and Social Science, medicine, 2.1 Biological and endogenous factors, Humans, Attention, Aetiology, Stress Disorders, Behavior, Brain Mapping, medicine.diagnostic_test, Rehabilitation, Neurosciences, Traumatic stress, General Medicine, Biological Sciences, Serious Mental Illness, Post-Traumatic Stress Disorder (PTSD), medicine.disease, Anxiety Disorders, Magnetic Resonance Imaging, Transcranial Magnetic Stimulation, Brain Disorders, 030227 psychiatry, Transcranial magnetic stimulation, Mental Health, Treatment Outcome, Mental Recall, Post-Traumatic, Verbal memory, Nerve Net, Functional magnetic resonance imaging, Neuroscience, 030217 neurology & neurosurgery
Abstract

A mechanistic understanding of the pathology of psychiatric disorders has been hampered by extensive heterogeneity in biology, symptoms, and behavior within diagnostic categories that are defined subjectively. We investigated whether leveraging individual differences in information-processing impairments in patients with post-traumatic stress disorder (PTSD) could reveal phenotypes within the disorder. We found that a subgroup of patients with PTSD from two independent cohorts displayed both aberrant functional connectivity within the ventral attention network (VAN) as revealed by functional magnetic resonance imaging (fMRI) neuroimaging and impaired verbal memory on a word list learning task. This combined phenotype was not associated with differences in symptoms or comorbidities, but nonetheless could be used to predict a poor response to psychotherapy, the best-validated treatment for PTSD. Using concurrent focal noninvasive transcranial magnetic stimulation and electroencephalography, we then identified alterations in neural signal flow in the VAN that were evoked by direct stimulation of that network. These alterations were associated with individual differences in functional fMRI connectivity within the VAN. Our findings define specific neurobiological mechanisms in a subgroup of patients with PTSD that could contribute to the poor response to psychotherapy.

Published
2019

17. The other office

Author

Elizabeth T Toll

Subjects
Government, Medical knowledge, Physician-Patient Relations, Primary Health Care, business.industry, 010102 general mathematics, Foundation (evidence), Cognitive complexity, Health Informatics, Public relations, Burnout, 01 natural sciences, 03 medical and health sciences, Interpersonal relationship, 0302 clinical medicine, Documentation, Physicians, Premise, Perspective, Electronic Health Records, Humans, 030212 general & internal medicine, 0101 mathematics, Psychology, business
Abstract

Across recent decades, profound changes in the practice of medicine have been accompanied by parallel developments in the daily mental efforts of medical professionals. Using visual metaphors and hand-drawn illustrations, the author explores the evolution of one physician’s brain over the past 25 years. At the completion of training, the patient-practitioner relationship, medical knowledge, and care decisions dominated clinician thought, time, and effort. During the 1990’s, the growing constraints of third-party payers and government regulations presented new challenges to delivering relationship-based care. Over the past decade, the electronic health record (EHR) has added further cognitive complexity, disrupted human relationships, and contributed significantly to the current epidemic of clinician burnout. Solutions to these challenges include rethinking education, documentation, professional standards, institutional barriers, and regulatory mandates. It is important to pursue all solutions with the underlying premise of protecting healing relationships as the foundation of clinical care.

Published
2018

18. Molecular and clinical profile of von willebrand disease in spain (PCM-EVW-ES): Proposal for a new diagnostic paradigm

Author

Esther Lourés, María del Mar Nieto, L. Sarmiento, Rafael Parra, Jorge Cuesta, O. Arija, Javier Batlle, Faustino García-Candel, Víctor Jiménez-Yuste, J. M. César, Ana María Rodríguez-Huerta, Rosa Vidal, Karmele Arribalzaga, Rosa Campos, María Paz Martínez, Ramón Rodríguez-González, Francisco Vidal, Sonia Herrero, Nuria Bermejo, María Ferreiro, Almudena Pérez-Rodríguez, R. Cornudella, Javier García-Frade, Maria Eva Mingot-Castellano, Rosa Fisac, Ángela Rodríguez-Trillo, Pascual Marco, I. Balda, Ana Rosa Cid, Reyes Aguinaco, D. Vilariño, Irene Corrales, T. Toll, José Mateo, Ángeles Palomo, N. Cabrera, Santiago Bonanad, María Fernanda López-Fernández, Nieves Alonso, Belén Iñigo, Andrés Moret, Inmaculada Soto, Rocío Pérez-Montes, Nina Borràs, Gemma Iruin, B. de Rueda, Carlos Aguilar, María José Paloma, and Carmen Altisent

Subjects
Genetic Markers, Male, medicine.medical_specialty, congenital, hereditary, and neonatal diseases and abnormalities, phenotype, genotype, DNA Mutational Analysis, 030204 cardiovascular system & hematology, Bioinformatics, 03 medical and health sciences, 0302 clinical medicine, Von Willebrand factor, Predictive Value of Tests, Risk Factors, Internal medicine, hemic and lymphatic diseases, von Willebrand Factor, Genotype, medicine, Von Willebrand disease, Humans, VWF, Genetic Predisposition to Disease, Registries, Genetic Association Studies, VWD, Molecular Epidemiology, biology, Case-control study, High-Throughput Nucleotide Sequencing, Hematology, NGS, VWD, VWF, genotype, phenotype, medicine.disease, Phenotype, von Willebrand Diseases, Spain, Case-Control Studies, Predictive value of tests, NGS, Mutation, Cohort, biology.protein, Female, Leiden Open Variation Database, 030215 immunology
Abstract

SummaryThe diagnosis of von Willebrand disease (VWD) remains difficult in a significant proportion of patients. A Spanish multicentre study investigated a cohort of 556 patients from 330 families who were analysed centrally. VWD was confirmed in 480. Next generation sequencing (NGS) of the whole coding VWF was carried out in all recruited patients, compared with the phenotype, and a final diagnosis established. A total of 238 different VWF mutations were found, 154 were not included in the Leiden Open Variation Database (LOVD). Of the patients, 463 were found to have VWF mutation/s. A good phenotypic/ genotypic association was estimated in 96.5 % of the patients. One hundred seventy-four patients had two or more mutations. Occasionally a predominant phenotype masked the presence of a second abnormality. One hundred sixteen patients presented with mutations that had previously been associated with increased von Willebrand factor (VWF) clearance. RIPA unavailability, central phenotypic results disagreement and difficult distinction between severe type 1 and type 3 VWD prevented a clear diagnosis in 70 patients. The NGS study facilitated an appropriate classification in 63 of them. The remaining seven patients presented with a VWF novel mutation pending further investigation. In five patients with a type 3 and two with a type 2A or 2B phenotype with no mutation, an acquired von Willebrand syndrome (AVWS) was suspected/confirmed. These data seem to support NGS as a first line efficient and faster paradigm in VWD diagnosis.Supplementary Material to this article is available online at www.thrombosis-online.com.

Published
2016

19. Nitrogen Diffusion at Low Temperature in fcc Materials Deformed by Attrition Peening

Author

T. Belmonte, Tony Thiriet, G. Marcos, T. Toll-Duchanoy, B. Brugier, Dominique Hertz, M. Foucault, Thierry Czerwiec, and S. Migot

Subjects
Secondary ion mass spectrometry, Radiation, Materials science, Scanning electron microscope, Metallurgy, Peening, General Materials Science, Texture (crystalline), Condensed Matter Physics, Shot peening, Indentation hardness, Nitriding, Electron backscatter diffraction
Abstract

Recent scientific work has opened new fields of application to mechanical treatments such as shot blasting or peening. Indeed, it has been shown that this treatment, performed before a nitriding treatment on the surface of ferrous alloy, lowers processing temperatures and significantly increases the diffusion kinetics. We undertook to test this combination of mechanical pretreatment and thermochemical treatment on stainless steels and nickel-based alloys. The mechanical treatments were done by surface attrition peening. The pretreated samples were then nitrided at low temperature using remote plasma. In this paper, the results obtained after nitriding treatments on samples treated by attrition peening are compared to those nitrided only. The use of X-ray diffraction, microhardness measurement, observations by optical and scanning electron microscopy, texture analysis by EBSD (Electron BackScatered Diffraction) and measurement of nitrogen concentration profiles by SIMS (Secondary Ion Mass Spectrometry) allows quantifying the effects of the combined treatments.

Published
2012

21. T32. PTSD Subtype Identification Based on Resting-State EEG Functional Connectivity Biomarkers

Author

Amit Etkin, Emmanuel Shpigel, Roland Hart, Silas Mann, Yu Zhang, Parker Longwell, Wei Wu, Bryan Gonzalez, Duna Abu Amara, Russell T. Toll, and Charles R. Marmar

Subjects
business.industry, Functional connectivity, 0206 medical engineering, 02 engineering and technology, 020601 biomedical engineering, 030218 nuclear medicine & medical imaging, 03 medical and health sciences, 0302 clinical medicine, Resting state eeg, Medicine, Identification (biology), business, Neuroscience, Biological Psychiatry
Published
2018

22. Measurement of the D∗± meson production cross section and F2cc¯ at high Q2 in ep scattering at HERA

Author

F.D. Aaron, C. Alexa, K. Alimujiang, V. Andreev, B. Antunovic, S. Backovic, A. Baghdasaryan, E. Barrelet, W. Bartel, K. Begzsuren, A. Belousov, J.C. Bizot, V. Boudry, I. Bozovic-Jelisavcic, J. Bracinik, G. Brandt, M. Brinkmann, V. Brisson, D. Bruncko, A. Bunyatyan, G. Buschhorn, L. Bystritskaya, A.J. Campbell, K.B. Cantun Avila, K. Cerny, V. Cerny, V. Chekelian, A. Cholewa, J.G. Contreras, J.A. Coughlan, G. Cozzika, J. Cvach, J.B. Dainton, K. Daum, M. Deák, B. Delcourt, J. Delvax, E.A. De Wolf, C. Diaconu, V. Dodonov, A. Dossanov, A. Dubak, G. Eckerlin, V. Efremenko, S. Egli, A. Eliseev, E. Elsen, A. Falkiewicz, L. Favart, A. Fedotov, R. Felst, J. Feltesse, J. Ferencei, D.-J. Fischer, M. Fleischer, A. Fomenko, E. Gabathuler, J. Gayler, S. Ghazaryan, A. Glazov, I. Glushkov, L. Goerlich, N. Gogitidze, M. Gouzevitch, C. Grab, T. Greenshaw, B.R. Grell, G. Grindhammer, S. Habib, D. Haidt, C. Helebrant, R.C.W. Henderson, E. Hennekemper, H. Henschel, M. Herbst, G. Herrera, M. Hildebrandt, K.H. Hiller, D. Hoffmann, R. Horisberger, T. Hreus, M. Jacquet, X. Janssen, L. Jönsson, A.W. Jung, H. Jung, M. Kapichine, J. Katzy, I.R. Kenyon, C. Kiesling, M. Klein, C. Kleinwort, T. Kluge, A. Knutsson, R. Kogler, P. Kostka, M. Kraemer, K. Krastev, J. Kretzschmar, A. Kropivnitskaya, K. Krüger, K. Kutak, M.P.J. Landon, W. Lange, G. Laštovička-Medin, P. Laycock, A. Lebedev, V. Lendermann, S. Levonian, G. Li, K. Lipka, A. Liptaj, B. List, J. List, N. Loktionova, R. Lopez-Fernandez, V. Lubimov, A. Makankine, E. Malinovski, P. Marage, Ll. Marti, H.-U. Martyn, S.J. Maxfield, A. Mehta, A.B. Meyer, H. Meyer, J. Meyer, S. Mikocki, I. Milcewicz-Mika, F. Moreau, A. Morozov, J.V. Morris, M.U. Mozer, M. Mudrinic, K. Müller, P. Murín, Th. Naumann, P.R. Newman, C. Niebuhr, A. Nikiforov, D. Nikitin, G. Nowak, K. Nowak, J.E. Olsson, S. Osman, D. Ozerov, P. Pahl, V. Palichik, I. Panagoulias, M. Pandurovic, Th. Papadopoulou, C. Pascaud, G.D. Patel, O. Pejchal, E. Perez, A. Petrukhin, I. Picuric, S. Piec, D. Pitzl, R. Plačakytė, B. Pokorny, R. Polifka, B. Povh, V. Radescu, A.J. Rahmat, N. Raicevic, A. Raspiareza, T. Ravdandorj, P. Reimer, E. Rizvi, P. Robmann, B. Roland, R. Roosen, A. Rostovtsev, M. Rotaru, J.E. Ruiz Tabasco, S. Rusakov, D. Šálek, D.P.C. Sankey, M. Sauter, E. Sauvan, S. Schmitt, L. Schoeffel, A. Schöning, H.-C. Schultz-Coulon, F. Sefkow, R.N. Shaw-West, L.N. Shtarkov, S. Shushkevich, T. Sloan, I. Smiljanic, Y. Soloviev, P. Sopicki, D. South, V. Spaskov, A. Specka, Z. Staykova, M. Steder, B. Stella, G. Stoicea, U. Straumann, D. Sunar, T. Sykora, V. Tchoulakov, G. Thompson, P.D. Thompson, T. Toll, F. Tomasz, T.H. Tran, D. Traynor, T.N. Trinh, P. Truöl, I. Tsakov, B. Tseepeldorj, J. Turnau, K. Urban, A. Valkárová, C. Vallée, P. Van Mechelen, A. Vargas Trevino, Y. Vazdik, S. Vinokurova, V. Volchinski, M. von den Driesch, D. Wegener, Ch. Wissing, E. Wünsch, J. Žáček, J. Zálešák, Z. Zhang, A. Zhokin, T. Zimmermann, H. Zohrabyan, and F. Zomer

Subjects
Physics, Quantum chromodynamics, Nuclear and High Energy Physics, Particle physics, Luminosity (scattering theory), Proton, Meson, 010308 nuclear & particles physics, Scattering, HERA, 7. Clean energy, 01 natural sciences, Nuclear physics, 0103 physical sciences, D meson, High Energy Physics::Experiment, Charm (quantum number), 010306 general physics
Abstract

The inclusive production of D*(+/-)(2010) mesons in deep-inelastic e(+/-)p scattering is measured in the kinematic region of photon virtuality 100 1 5 GeV The data were collected by the H1 experiment during the period from 2004 to 2007 and correspond to an integrated luminosity of 351 pb(-1) The charm contribution. F-2(c (c) over bar), to the proton structure function F-2 is determined. The measurements are compared with QCD predictions. (C) 2010 Elsevier B V All rights reserved

Published
2010

23. Deeply virtual Compton scattering and its beam charge asymmetry in e±p collisions at HERA

Author

K. H. Hiller, R. C. W. Henderson, Pavel Murin, Judith Katzy, Calin Alexa, V. Tchoulakov, R.N. Shaw-West, T. Toll, A. D.R. Vargas Trevino, Laurent Favart, S. Habib, S. Ghazaryan, B. Olivier, R. Kogler, E. E. Elsen, Ivan Smiljanic, Emmanuelle Perez, Stephen Maxfield, S. M. Piec, I. R. Kenyon, H. U. Martyn, J-P. Meyer, K. Lipka, T. N. Trinh, R. Zus, J. G. Contreras, Paul Laycock, E. Malinovski, Emmanuel Sauvan, C. Wissing, Ilias Panagoulias, G. Grindhammer, K. Krüger, B. R. Grell, B. Pokorny, J. Žáček, D. Wegener, A. Raspiareza, M. Sauter, Andrew Mehta, N. Gogitidze, A. Specka, M. Kapichine, M. Nozicka, B. Delcourt, Max Klein, B. Stella, Stefan Schmitt, U. Straumann, V. Lubimov, P. E. Reimer, Th. Naumann, F. Tomasz, A. W. Jung, A. Dubak, Fabian Zomer, K. Urban, David M. South, V. Efremenko, P. Sopicki, Tomas Hreus, G. Leibenguth, A. M. Fomenko, Maxime Gouzevitch, A. Knutsson, J. Zálešák, V. Lendermann, V. Spaskov, G. Herrera, S. Shushkevich, Murrough Landon, Sakar Osman, Vladimir Palichik, Paul Richard Newman, Grzegorz Nowak, Mila Pandurovic, A. Falkiewicz, G. Cozzika, N. Loktionova, S. Mikocki, A. Eliseev, A. Nikiforov, L. N. Shtarkov, K. Alimujiang, Hannes Jung, Alexander Zhokin, O. Pejchal, E. Gabathuler, A. Dossanov, R. Pla akyt, T. J. Sloan, V. Andreev, A.S. Belousov, A. Petrukhin, A. Baghdasaryan, A. Rostovtsev, Ll. Marti, I. Bozovic-Jelisavcic, J. Cvach, Th D. Papadopoulou, Sergey Rusakov, P. Truöl, Pierre Marage, C. Vallée, M. Herbst, M. Deak, V. Cerny, G. Thompson, K. Nowak, P. Van Mechelen, K. Krastev, T.H. Tran, Benno List, John A Coughlan, J. Bracinik, H-C. Schultz-Coulon, G. La tovi ka-Medin, E. Wünsch, T. Kluge, Z. Staykova, M. E. Janssen, A. B. Meyer, Christian Helebrant, A. Makankine, G. Buschhorn, Gabriel Stoicea, D. Ozerov, Wolfgang Lange, Gerhard Brandt, K. Daum, J. Gayler, Karel Cerny, V. Michels, V. Volchinski, D.K. Nikitin, Dirk L. Hoffmann, J. B. Dainton, Leif J. Jönsson, Roland Horisberger, D. J. Fischer, A. Valkárová, Krzysztof Kutak, Y. Vazdik, P.D. Thompson, H. Henschel, J.C. Bizot, A. Glazov, M. Brinkmann, C. Niebuhr, Benoit Roland, S. Egli, J. Delvax, M. Aldaya Martin, V. Brisson, K. Müller, Xavier Janssen, I. Picuric, Zhen Zhang, I. Glushkov, Guenter Eckerlin, André Schöning, Peter Robmann, Ricardo Lopez-Fernandez, Matthias Ulrich Mozer, Y. Soloviev, Dusan Bruncko, A. Fedotov, K. B. Cantun Avila, C. Kiesling, T. Zimmermann, E. Barrelet, F. Moreau, Gang Li, M. Steder, T. Greenshaw, A. J. Campbell, E. Hennekemper, M. von den Driesch, G. D. Patel, M. Jacquet, S. Backovic, J. E. Ruiz Tabasco, E. A. De Wolf, Voica Radescu, Zuzana Rurikova, Christoph Grab, R. Roosen, H. Meyer, Biljana Antunović, S. Levonian, D. álek, Y. de Boer, S. Vinokurova, J. Ferencei, I. Milcewicz-Mika, L. Bystritskaya, J. E. Olsson, W. Bartel, Malte Hildebrandt, P. Kostka, T. Sykora, T. Ravdandorj, Claus Kleinwort, M. Kraemer, J. Turnau, H. Zohrabyan, K. Begzsuren, Richard Polifka, Natasa Raicevic, M. Mudrinic, I. Tsakov, V. Chekelian, F. D. Aaron, J. Feltesse, J. V. Morris, Jenny List, Vincent Boudry, A. N. Morozov, M. Fleischer, A.J. Rahmat, A. Bunyatyan, Marina Rotaru, D. Sunar, C. Pascaud, A. Cholewa, Bogdan Povh, F. Sefkow, A. Lebedev, Cristinel Diaconu, Daniel Pitzl, D. Traynor, D. Haidt, Jan Kretzschmar, Andrej Liptaj, Eram Rizvi, V. Dodonov, Laurent Schoeffel, B. Tseepeldorj, D. P. C. Sankey, Anna Kropivnitskaya, R. Felst, M. Del Degan, and L. Goerlich

Subjects
Physics, Nuclear and High Energy Physics, Particle physics, Photon, 010308 nuclear & particles physics, media_common.quotation_subject, Momentum transfer, Compton scattering, Parton, HERA, 01 natural sciences, Asymmetry, Nuclear physics, Dipole, 0103 physical sciences, High Energy Physics::Experiment, 010306 general physics, P system, media_common
Abstract

A measurement of elastic deeply virtual Compton scattering gamma*p --> gamma p using e(+) p and e(-) p collision data recorded with the HI detector at HERA is presented. The analysed data sample corresponds to an integrated luminosity of 306 pb(-1), almost equally shared between both beam charges. The cross section is measured as a function of the virtuality Q(2) of the exchanged photon and the centre-of-mass energy W of the gamma*p system in the kinematic domain 6.5 < Q(2) < 80 GeV2, 30 < W < 140 GeV and |t| < 1 GeV2, where t denotes the squared momentum transfer at the proton vertex. The cross section is determined differentially in t for different Q(2) and W values and exponential t-slope parameters are derived. Using e(+) p and e(-) p data samples, a beam charge asymmetry is extracted for the first time in the low Biorken x kinematic domain. The observed asymmetry is attributed to the interference between Bethe-Heitler and deeply virtual Compton scattering processes. Experimental results are discussed in the context of two different models, one based on generalised parton distributions and one based on the dipole approach. (C) 2009 Elsevier B.V. All rights reserved.

Published
2009

24. Microstructure and phase composition of microarc oxidation surface layers formed on aluminium and its alloys 2214-T6 and 7050-T74

Author

K. Tillous, T. Toll-Duchanoy, E. Bauer-Grosse, L. Hericher, and Guillaume Geandier

Subjects
Diffraction, Materials science, chemistry.chemical_element, Surfaces and Interfaces, General Chemistry, Substrate (electronics), Condensed Matter Physics, Microstructure, Surfaces, Coatings and Films, Crystallography, Dendrite (crystal), chemistry, Chemical engineering, Aluminium, Transmission electron microscopy, Phase (matter), Materials Chemistry, Layer (electronics)
Abstract

The influence of substrate on the microstructure and phase composition of surface layers synthesised by microarc oxidation (MAO) on aluminium and its alloys 2214-T6 and 7050-T74 is studied using scanning (SEM) and transmission electron microscopy (TEM) as well as cross-sectional X-ray diffraction. MAO layers are composed of three layers and are mainly made of gamma-Al2O3 and alpha-Al2O3 phases. The proportion of each phase depends on the substrate. The external porous layer is mainly composed of the gamma-Al2O3 phase. The internal dense layer can present two aspects according to the percentage of the alpha-Al2O3 phase. The so-called granular aspect indicates a high proportion of “dendrite” defect which results from discharge formation and implies a high percentage of the alpha-Al2O3 phase. The so-called columnar aspect indicates a high proportion of “small channels” associated with a very weak percentage in the alpha-Al2O3 phase. In the latter, it is believed that a Zn alloying element can inhibit the growth of alpha-Al2O3. During the MAO process, discharges likely occur in the vicinity of the MAO layer/substrate interface, probably in the spherical porosities that result from oxygen generated in the thin layer localised at the interface.

Published
2009

25. Microstructure and 3D microtomographic characterization of porosity of MAO surface layers formed on aluminium and 2214-T6 alloy

Author

E. Bauer-Grosse, E.K. Tillous, and T. Toll-Duchanoy

Subjects
Materials science, Metallurgy, Alloy, chemistry.chemical_element, Surfaces and Interfaces, General Chemistry, engineering.material, Condensed Matter Physics, Microstructure, Surfaces, Coatings and Films, Coating, chemistry, Aluminium, visual_art, Materials Chemistry, Aluminium alloy, visual_art.visual_art_medium, engineering, Surface layer, Composite material, Porosity, Layer (electronics)
Abstract

A fine characterization of the microstructure of the MAO coatings formed on aluminium (purity 99,999%) and its alloy 2214-T6 was observed using field emission gun scanning electron microscopy (FEG-SEM) with energy dispersive spectrometry (EDS) and X-ray microtomography (XMT). In addition, the influence of current frequency (pure aluminium) and the precipitates of substrate were investigated (case of 2214-T6 alloy). The MAO surface layers formed on aluminium and its alloy 2214-T6 can be divided into two parts: the outer layer with high porosity (so-call porous layer) and the inner layer with low porosity (so-call dense layer). However, the porosity of the inner layer increases toward the MAO layer/substrate interface. It is found that, both the thickness and the porosity increase when the current frequency decreases. The porosity of the MAO coating can be attributed to discharges formation in the vicinity of the MAO coating/substrate interface. In the particular case of 2214-T6 aluminium alloy (3.9% Cu), with coarse non-valve metal rich precipitates aligned perpendicular to the surface of the work electrode; the transformation of precipitates under discharge effect can provoke the formation of big channels, which go through the MAO surface layer. This last one induces local formation of a layer rich electrolyte species toward the substrate.

Published
2009

26. Inclusive photoproduction of ρ0, K∗0 and ϕ mesons at HERA

Author

J. V. Morris, Jenny List, A.J. Rahmat, A. Bunyatyan, Marina Rotaru, Katerina Lipka, V. Tchoulakov, G. Laštovička-Medin, R.N. Shaw-West, F. Moreau, S. J. Aplin, C. Niebuhr, G. Leibenguth, A. D.R. Vargas Trevino, A. Astvatsatourov, Mila Pandurovic, S. Egli, Y. Soloviev, K. H. Hiller, K. Daum, R. C. W. Henderson, A. Specka, Matthias Ulrich Mozer, A. Fedotov, M. Kraemer, M. Gouzevitch, R. Kogler, J. Žáček, U. Straumann, Magnus Hansson, Voica Radescu, Christoph Grab, Richard Polifka, A. Knutsson, M. Deak, K. B. Cantun Avila, E. Wünsch, T. Toll, S. Shushkevich, Sakar Osman, V. Chekelian, M. Del Degan, B. R. Grell, V. Lendermann, F. D. Aaron, Judith Katzy, C. Wissing, A. Eliseev, C. Kiesling, Pavel Murin, Tim Greenshaw, J-P. Meyer, V. Jemanov, D. Wegener, J. Delvax, A. J. Campbell, G. Thompson, Paul Laycock, E. Malinovski, Emmanuel Sauvan, M. von den Driesch, Wolfgang Lange, G. D. Patel, Biljana Antunović, F. Tomasz, A. Raspiareza, Stephen Maxfield, David M. South, P. E. Reimer, Z. Staykova, J. Bracinik, I. R. Kenyon, Karel Cerny, Th. D. Papadopoulou, B. Stella, J. Gayler, T. Sykora, M. Sauter, A. Baghdasaryan, A. Rostovtsev, A. Schöning, Tomas Hreus, Stefan Schmitt, G. Grindhammer, T. H. Tran, I. Sheviakov, V. Efremenko, L. Goerlich, M. E. Janssen, Roland Horisberger, T. Kluge, A. Lebedev, J. Ferencei, A. Valkárová, Laurent Schoeffel, Andrew Mehta, N. Gogitidze, H. Henschel, Laurent Favart, D. Haidt, A. De Roeck, A. Nikiforov, K. Krastev, A. Glazov, J.C. Bizot, S. Mikocki, Fabian Zomer, Vladimir Andreev, Peter Robmann, K. Urban, Eram Rizvi, Calin Alexa, Gabriel Stoicea, H. U. Martyn, Matthias Klein, Murrough Landon, V. Korbel, J. Zálešák, A. Makankine, A. Dubak, V. Dodonov, V. Spaskov, S. Ghazaryan, G. Buschhorn, D. Ozerov, Vladimir Palichik, Ll. Marti, G. Cozzika, I. Picuric, C. Pascaud, T. Zimmermann, A. B. Meyer, V. Cerny, D. J. Fischer, B. Olivier, A. W. Jung, Zhen Zhang, Ricardo Lopez-Fernandez, S. Backovic, I. Bozovic-Jelisavcic, M. Herbst, Y. Vazdik, Zuzana Rurikova, E. E. Elsen, S. Vinokurova, M. Jacquet, Guenter Eckerlin, Nicolas Berger, I. Panagoulias, G. Herrera, P.D. Thompson, V. Michels, P. Van Mechelen, J. B. Dainton, B. Tseepeldorj, M. Steder, D. Hoffmann, P. Kostka, Ivan Smiljanic, C. Schmitz, Dusan Bruncko, Hannes Jung, B. Naroska, D. P. C. Sankey, J. Turnau, Alexander Zhokin, S. Levonian, John A Coughlan, J. E. Olsson, C. Vallée, D. Salek, E. Hennekemper, K. Begzsuren, M. Mudrinic, I. Tsakov, L. Bystritskaya, W. Bartel, Th. Naumann, Christian Helebrant, T. Ravdandorj, Claus Kleinwort, Leif J. Jönsson, Benoit Roland, Malte Hildebrandt, Anna Kropivnitskaya, Gang Li, Gerhard Brandt, V. Volchinski, M. Kapichine, M. Nozicka, R. Felst, Emmanuelle Perez, J. G. Contreras, H. Meyer, H. Zohrabyan, B. Delcourt, Xavier Janssen, I. Milcewicz-Mika, S. M. Piec, E. Gabathuler, T. N. Trinh, M. Fleischer, Natasa Raicevic, J. Feltesse, J. Cvach, Vincent Boudry, O. Pejchal, A. N. Morozov, Bogdan Povh, F. Sefkow, Benno List, R. Plačakytė, P. Sopicki, A. M. Fomenko, K. Nowak, H-C. Schultz-Coulon, M. Brinkmann, Krzysztof Kutak, T. J. Sloan, P.J.W. Faulkner, A.S. Belousov, Sergey Rusakov, P. Truöl, K. Müller, N. Loktionova, T. Preda, E. Barrelet, J. E. Ruiz Tabasco, E. A. De Wolf, Karlheinz Meier, R. Roosen, Y. de Boer, Paul Richard Newman, Grzegorz Nowak, A. Dossanov, A. Petrukhin, S. Habib, V. Brisson, A. Falkiewicz, K. Krüger, V. Lubimov, L. N. Shtarkov, Daniel Pitzl, D. Traynor, A. Asmone, F. Cassol-Brunner, Jan Kretzschmar, Andrej Liptaj, Pierre Marage, I. Glushkov, O. Behnke, D. Sunar, A. Cholewa, L. Lytkin, and Cristinel Diaconu

Subjects
Physics, Nuclear and High Energy Physics, Particle physics, Meson, 010308 nuclear & particles physics, High Energy Physics::Phenomenology, HERA, 01 natural sciences, 0103 physical sciences, Transverse momentum, High Energy Physics::Experiment, Rapidity, Nuclear Experiment, 010306 general physics
Abstract

Inclusive non-diffractive photoproduction of rho(770)(0), K*(892)(0) and phi(1020) mesons is investigated with the H1 detector in ep collisions at HERA. The corresponding average gamma p centre-of-mass energy is 210 GeV. The mesons are measured in the transverse momentum range 0.5 < p(T) < 7 GeV and the rapidity range vertical bar y(lab)vertical bar < 1. Differential cross sections are presented as a function of transverse momentum and rapidity, and are compared to the predictions of hadroproduction models. (C) 2009 Elsevier B.V. All rights reserved.

Published
2009

27. Measurement of diffractive scattering of photons with large momentum transfer at HERA

Author

J. Feltesse, David M. South, H. Peng, Leif J. Jönsson, Benoit Roland, A. Baghdasaryan, A. Rostovtsev, K. H. Hiller, R. C. W. Henderson, Matthias Ulrich Mozer, T. Klimkovich, A. Fedotov, S. Vinokurova, K. B. Cantun Avila, M. E. Janssen, P. Kostka, Paul Laycock, J. Turnau, E. Malinovski, Emmanuel Sauvan, Stephen Maxfield, V. Lubimov, P. A. Smirnov, C. Kiesling, E. Tzamariudaki, A. J. Campbell, K. Nankov, L. N. Shtarkov, E. E. Elsen, G. Grindhammer, E. Wünsch, A. Specka, K. Begzsuren, T. H. Tran, Dave Sankey, S. Habib, A. Falkiewicz, I. R. Kenyon, J. E. Olsson, Laurent Schoeffel, M. Mudrinic, J. Delvax, K. Krüger, Peter Robmann, Alessandro Bacchetta, I. Tsakov, W. Bartel, Pierre Marage, Emmanuelle Perez, L. Bystritskaya, Matthew Beckingham, Andrew Mehta, C. Niebuhr, N. Gogitidze, P. E. Reimer, Th. Naumann, Malte Hildebrandt, K. Urban, Murrough Landon, G. D. Patel, Biljana Antunović, B. Stella, Anna Kropivnitskaya, Roland Horisberger, J. Žáček, G. Leibenguth, H. U. Martyn, Matthias Klein, I. Glushkov, A. Valkárová, S. Egli, R. Felst, Stefan Schmitt, H. Zohrabyan, Katerina Lipka, T. Sykora, V. Tchoulakov, R.N. Shaw-West, Zhiqing Zhang, T. Zimmermann, Natasa Raicevic, Y. Soloviev, E. Gabathuler, V. Michels, J. B. Dainton, D. Wegener, M. Fleischer, S. M. Piec, M. Gouzevitch, Hans-Christian Schultz-Coulon, Vincent Boudry, A. N. Morozov, V. Yeganov, P. Van Mechelen, G. Laštovička-Medin, Gerhard Brandt, Voica Radescu, A. Lebedev, F. Salvaire, D. Haidt, B. R. Grell, A. De Roeck, Eram Rizvi, M. Kapichine, M. Nozicka, A. Nikiforov, O. Behnke, I. Sheviakov, S. Backovic, Daniel Pitzl, U. Straumann, Ll. Marti, Vladimir Palichik, Bogdan Povh, F. Sefkow, Gang Li, B. Delcourt, V. Lendermann, F. Moreau, S. J. Aplin, I. Bozovic-Jelisavcic, Christoph Grab, D. Traynor, A. Asmone, F. Tomasz, C. Wissing, L. Finke, R. Plačakytė, V. Dodonov, S. Shushkevich, Sakar Osman, A.-I. Lucaci-Timoce, V. Volchinski, Zuzana Rurikova, J. Zálešák, F. Cassol-Brunner, H. Meyer, Judith Katzy, Y.C. Zhu, K. Daum, A. Eliseev, V. Efremenko, Wolfgang Lange, V. Spaskov, P. Sopicki, A. M. Fomenko, B. Tseepeldorj, T. Kluge, Benno List, N. Loktionova, M. Brinkmann, A. Hovhannisyan, T. Preda, I. Tsurin, I. Milcewicz-Mika, O. Pejchal, I. Picuric, P. Baranov, M. Goettlich, J. Gayler, K. Krastev, Ricardo Lopez-Fernandez, I. Panagoulias, M. Steder, D. Hoffmann, S. Essenov, Fabian Zomer, G. Cozzika, C. Schmitz, A. Astvatsatourov, Mila Pandurovic, Jan Kretzschmar, Andrej Liptaj, A. D.R. Vargas Trevino, D. Sunar, R. Kogler, Karel Cerny, J. Bracinik, A. Schöning, A. Knutsson, A. Makankine, G. Buschhorn, D. Ozerov, J. V. Morris, Jenny List, Calin Alexa, A.J. Rahmat, A. Bunyatyan, Marina Rotaru, S. Ghazaryan, Tomas Hreus, V. Jemanov, A. Raspiareza, M. Sauter, A. B. Meyer, A. Dubak, Dusan Bruncko, B. Naroska, Y. Vazdik, P.D. Thompson, T. Greenshaw, Xavier Janssen, T. N. Trinh, J-P. Meyer, T. Toll, S. Mikocki, C. Pascaud, Guenter Eckerlin, T. J. Sloan, P.J.W. Faulkner, V. Cerny, Hannes Jung, Alexander Zhokin, C. Vallée, M. Deak, M.-O. Boenig, D. Johnson, A. Glazov, V. Korbel, J. Ferencei, B. Olivier, Nicolas Berger, A.S. Belousov, Sergey Rusakov, P. Truöl, S. Levonian, G. Thompson, A. Zhelezov, Z. Staykova, V. Andreev, John A Coughlan, A. Cholewa, H. Henschel, Magnus Hansson, M. Jacquet, J.C. Bizot, T. Ravdandorj, Claus Kleinwort, M. Kraemer, M. Del Degan, L. Lytkin, Christian Helebrant, Richard Polifka, Cristinel Diaconu, L. Goerlich, S. Schmidt, V. Chekelian, F. D. Aaron, E. Barrelet, A. W. Jung, G. Herrera, J. E. Ruiz Tabasco, E. A. De Wolf, Krzysztof Kutak, Karlheinz Meier, R. Roosen, Y. de Boer, K. Müller, Paul Richard Newman, Grzegorz Nowak, A. Dossanov, A. Petrukhin, J. Cvach, K. Nowak, Michael R. Wessels, V. Brisson, Ivan Smiljanic, D. Salek, J. G. Contreras, Pavel Murin, Th. D. Papadopoulou, Laurent Favart, Laboratoire de Physique Nucléaire et de Hautes Énergies (LPNHE), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de l'Accélérateur Linéaire (LAL), Université Paris-Sud - Paris 11 (UP11)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Laboratoire Leprince-Ringuet (LLR), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-École polytechnique (X)-Centre National de la Recherche Scientifique (CNRS), Centre de Physique des Particules de Marseille (CPPM), Aix Marseille Université (AMU)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Institut de Recherches sur les lois Fondamentales de l'Univers (IRFU), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, H1, (ukupan broj autora: 274), H1 Collaboration, Centre National de la Recherche Scientifique (CNRS)-Université Paris Diderot - Paris 7 (UPD7)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Pierre et Marie Curie - Paris 6 (UPMC), Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris-Sud - Paris 11 (UP11), and Centre National de la Recherche Scientifique (CNRS)-École polytechnique (X)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)

Subjects
Diffraction, Particle physics, Nuclear and High Energy Physics, Photon, FOS: Physical sciences, Physics::Optics, 01 natural sciences, 7. Clean energy, High Energy Physics - Experiment, Nuclear physics, High Energy Physics - Experiment (hep-ex), 0103 physical sciences, [PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex], ddc:530, Vector meson, Nuclear Experiment, 010306 general physics, Physics, 010308 nuclear & particles physics, Scattering, Momentum transfer, Perturbative QCD, HERA, Vertex (geometry), Physique des particules élémentaires, High Energy Physics::Experiment
Abstract

The first measurement of diffractive scattering of quasi-real photons with large momentum transfer γ p → γ Y, where Y is the proton dissociative system, is made using the H1 detector at HERA. The measurement is performed for initial photon virtualities Q 2 < 0.01 GeV 2. Single differential cross sections are measured as a function of W, the incident photon-proton centre of mass energy, and t, the square of the four-momentum transferred at the proton vertex, in the range 175 < W < 247 GeV and 4 <, 0, SCOPUS: ar.j, info:eu-repo/semantics/published

Published
2009
Full Text
View/download PDF

28. Measurement of the proton structure function FL(x,Q2) at low x

Author

L. Finke, Roland Horisberger, H. Peng, Y.C. Zhu, K. Daum, A. Valkárová, K. H. Hiller, R. C. W. Henderson, Matthias Ulrich Mozer, B. R. Grell, A. Fedotov, K. B. Cantun Avila, Calin Alexa, F. Tomasz, S. Vinokurova, T. Kluge, David M. South, S. Shushkevich, Sakar Osman, A. Eliseev, E. E. Elsen, J. Bracinik, P. Kostka, A. Specka, I. Sheviakov, J. Ferencei, Laurent Schoeffel, Judith Katzy, P. E. Reimer, E. Wuensch, C. Kiesling, E. Tzamariudaki, A. J. Campbell, J. Turnau, K. Begzsuren, M. Mudrinic, Alessandro Bacchetta, I. Tsakov, I. Picuric, C. Pascaud, A. Makankine, Pavel Murin, J. Zálešák, K. Urban, Murrough Landon, K. Krastev, V. Spaskov, G. Li, S. Ghazaryan, G. Buschhorn, D. Ozerov, Th. D. Papadopoulou, Paul Laycock, Emmanuelle Perez, Tim Greenshaw, V. Jemanov, Guenter Eckerlin, E. Malinovski, V. Yeganov, A. B. Meyer, Emmanuel Sauvan, M. Beckingharn, V. Michels, C. Wissing, A. Baghdasaryan, A. Rostovtsev, M. Kraemer, Leif J. Jönsson, Dave Sankey, Benoit Roland, J. Delvax, J. B. Dainton, G. Grindhammer, F. Moreau, S. J. Aplin, Ricardo Lopez-Fernandez, T. Klimkovich, Richard Polifka, S. M. Piec, A. Raspiareza, S. Schmidt, V. Chekelian, F. D. Aaron, Laurent Favart, A. Nikiforov, Karel Cerny, I. Panagoulias, M. Steder, M. Kapichine, M. Nozicka, D. Hoffmann, S. Habib, Th. Naumann, Ll. Marti, P. Van Mechelen, I. Bozovic-Jelisavcic, S. Essenov, M. Sauter, G. D. Patel, Wolfgang Lange, M. Goettlich, Biljana Antunović, Dusan Bruncko, O. Pejchal, J. Gayler, A. Falkiewicz, Krzysztof Kutak, B. Naroska, M. E. Janssen, E. Gabathuler, T. H. Tran, D.P. Johnson, J. E. Olsson, W. Bartel, T. Sykora, Malte Hildebrandt, B. Delcourt, G. Laštovička-Medin, A. Glazov, I. R. Kenyon, G. Leibenguth, T. Ravdandorj, Claus Kleinwort, E. Barrelet, A. D.R. Vargas Trevino, V. Lubimov, P. Baranov, M. Jacquet, Natasa Raicevic, Vincent Boudry, C. Niebuhr, Benno List, A. N. Morozov, R. Placakyte, J. E. Ruiz Tabasco, E. A. De Wolf, A. Knutsson, Karlheinz Meier, R. Roosen, M. Gouzevitch, J. V. Morris, Jenny List, R. Kogler, T. J. Sloan, P.J.W. Faulkner, Peter Robmann, I. Milcewicz-Mika, T. Zimmermann, A.S. Belousov, S. Egli, Sergey Rusakov, M. Fleischer, Zhiqing Zhang, K. Nankov, L. N. Shtarkov, J. Feltesse, J. Cvach, A. Dubak, Gerhard Brandt, A. Schoening, Y. de Boer, A.J. Rahmat, A. Bunyatyan, D. Salek, Marina Rotaru, S. Backovic, U. Straumann, Y. Soloviev, K. Nowak, Bogdan Povh, V. Volchinski, Zuzana Rurikova, N. Loktionova, F. Sefkow, H. Meyer, Y. Vazdik, A. Hovhannisyan, Stephen Maxfield, P.D. Thompson, M. Deak, T. Preda, K. Krueger, V. Korbel, Andrew Mehta, N. Gogitidze, J. Zacek, P. A. Smirnov, I. Tsurin, M. Brinkmann, Katerina Lipka, Xavier Janssen, Paul Richard Newman, Grzegorz Nowak, V. Tchoulakov, A. Dossanov, P. Sopicki, R.N. Shaw-West, Mila Pandurovic, A. M. Fomenko, A. Petrukhin, A. W. Jung, Voica Radescu, Christoph Grab, J. G. Contreras, T. N. Trinh, M.-O. Boenig, Vladimir Andreev, H. U. Martyn, Matthias Klein, G. Thompson, Z. Staykova, A. Lebedev, G. Herrera, Michael R. Wessels, Magnus Hansson, M. Del Degan, V. Brisson, F. Salvaire, Nicolas Berger, L. Goerlich, D. Haidt, A. De Roeck, H. Henschel, J.C. Bizot, B. Tseepeldorj, Eram Rizvi, S. Levonian, A. Zhelezov, V. Dodonov, G. Cozzika, Anna Kropivnitskaya, R. Felst, J-P. Meyer, I. Smijanic, V. Lendermann, C. Schmitz, Hannes Jung, Alexander Zhokin, C. Vallée, A.-I. Lucaci-Timoce, K. Mueller, L. Bystritskaya, H. Zohrabyan, D. Wegener, T. Toll, Hans-Christian Schultz-Coulon, V. Efremenko, Tomas Hreus, S. Mikocki, V. Cerny, B. Olivier, B. Stella, F. Zomer, Stefan Schmitt, Christian Helebrant, Vladimir Palichik, A. Astvatsatourov, John A Coughlan, Pierre Marage, I. Glushkov, O. Behnke, P. Truoel, D. Sunar, A. Cholewa, L. Lytkin, Cristinel Diaconu, Daniel Pitzl, D. Traynor, A. Asmone, F. Cassol-Brunner, Jan Kretzschmar, and Andrej Liptaj

Subjects
Quantum chromodynamics, Physics, Nuclear and High Energy Physics, Range (particle radiation), Particle physics, Proton, 010308 nuclear & particles physics, Parton, HERA, 01 natural sciences, law.invention, Nuclear physics, Cross section (physics), law, 0103 physical sciences, Physics::Accelerator Physics, High Energy Physics::Experiment, Nuclear Experiment, 010306 general physics, Collider, Beam (structure)
Abstract

A first measurement is reported of the longitudinal proton structure function FL(X, Q(2)) at the ep collider HERA. It is based on inclusive deep inelastic e(+)p scattering cross section measurements with a positron beam energy of 27.5 GeV and proton beam energies of 920, 575 and 460 GeV. Employing the energy dependence of the cross section, FL is measured in a range of squared four-momentum transfers 12

Published
2008

29. Measurement of inclusive jet production in deep-inelastic scattering at high and determination of the strong coupling

Author

E. Wünsch, G. Tsipolitis, M. Deak, Dave Sankey, Daniel Pitzl, J. Delvax, Wolfgang Lange, M. Goettlich, A. M. Fomenko, G. Thompson, Pavel Murin, D. Traynor, Z. Staykova, A. Asmone, J. E. Olsson, G. D. Patel, V. Lubimov, W. Bartel, T. Kluge, I. Picuric, Guenter Eckerlin, J. Gayler, Leif J. Jönsson, Benoit Roland, Malte Hildebrandt, Biljana Antunović, D.P. Johnson, Paul Richard Newman, Grzegorz Nowak, F. Cassol-Brunner, F. Eisele, T. Sykora, K. Müller, F. W. Büsser, C. Niebuhr, Th. Papadopoulou, M. Fleischer, R. Oganezov, A. Petrukhin, H. Henschel, J.C. Bizot, Bogdan Povh, F. Sefkow, Laurent Favart, T. Anthonis, S. Egli, M. Kraemer, T. Klimkovich, Natasa Raicevic, J. Feltesse, K. Nankov, Y. Soloviev, M. Kapichine, R. Plaakyt, L. N. Shtarkov, J. V. Morris, Jan Kretzschmar, Richard Polifka, S. Schmidt, C. Risler, V. Cerny, Vincent Boudry, B. Olivier, Jenny List, P. E. Reimer, K. H. Hiller, M. Nozicka, Peter Robmann, A.J. Rahmat, A. Bunyatyan, R. C. W. Henderson, N. Loktionova, Andrej Liptaj, A. N. Morozov, D. Perez-Astudillo, V. Chekelian, D. Sunar, Paul Laycock, E. Malinovski, Emmanuel Sauvan, G. Grindhammer, R. Weber, J. Cvach, A. Hovhannisyan, T. Preda, L. Finke, J. Zacek, C. Wissing, T. Toll, Ivan Smiljanic, B. Delcourt, Voica Radescu, Christoph Grab, Michael R. Wessels, V. Brisson, B. R. Grell, F. Tomasz, K. Nowak, Stephen Maxfield, T. N. Trinh, T. Zimmermann, J. Stiewe, I. Tsurin, V. Andreev, Katerina Lipka, David M. South, Sakar Osman, I. R. Kenyon, C. Pascaud, J. Záleák, A. Astvatsatourov, Mila Pandurovic, A. Cholewa, Andrew Mehta, J. Bracinik, V. Tchoulakov, N. Gogitidze, A. Lebedev, A. Eliseev, E. Barrelet, J. G. Contreras, A. Mohamed, S. Backovic, Zuzana Rurikova, A. W. Jung, P. Baranov, A. Baghdasaryan, A. Rostovtsev, Y.C. Zhu, P. Prideaux, F. Salvaire, D. Haidt, T. J. Sloan, K. Daum, Christian Helebrant, R.N. Shaw-West, I. Sheviakov, Eram Rizvi, G. Heinzelmann, Judith Katzy, E. A. De Wolf, Karlheinz Meier, R. Roosen, K. Krastev, L. Lytkin, Cristinel Diaconu, G. Latovika-Medin, Pierre Marage, A. Dubak, S. Levonian, V. Dodonov, G. Herrera, R. Wolf, M. E. Janssen, Fabian Zomer, Ll. Marti, Dirk L. Hoffmann, I. Bozovic-Jelisavcic, G. Franke, A. Specka, Y. de Boer, L. Lindfeld, S. Habib, P.J.W. Faulkner, John A Coughlan, A.S. Belousov, Sergey Rusakov, D. Utkin, P. Truöl, Hans-Christian Schultz-Coulon, V. Jemanov, I. Glushkov, V. Spaskov, Gang Li, G. Cozzika, E. E. Elsen, Roland Horisberger, A. Valkárová, Y. Vazdik, B. Stella, Stefan Schmitt, A. D.R. Vargas Trevino, Zhen Zhang, M. Jacquet, Ricardo Lopez-Fernandez, H. U. Martyn, A. Falkiewicz, P.D. Thompson, M. Sauter, D. Wegener, Emmanuelle Perez, K. Krüger, A. B. Meyer, C. Schmitz, M. Steder, Hannes Jung, Alexander Zhokin, C. Vallée, Stefania Xella, Tomas Hreus, R. Eichler, V. Yeganov, T. Frisson, S. M. Piec, O. Behrendt, H. Peng, S. Vinokurova, Vladimir Palichik, A. Aktas, I. Milcewicz-Mika, P. Kostka, V. Efremenko, Matthias Ulrich Mozer, F. Moreau, S. J. Aplin, S. Mikocki, O. Behnke, J. Turnau, Calin Alexa, A. Fedotov, Dusan Bruncko, B. Naroska, K. B. Cantun Avila, K. Begzsuren, S. Ginzburgskaya, C. Kiesling, A. De Roeck, E. Tzamariudaki, I. Tsakov, A. J. Campbell, S. Ghazaryan, Th. Naumann, K. Urban, G. Leibenguth, Murrough Landon, W. Yan, T. Greenshaw, E. Gabathuler, I. Panagoulias, A. Schöning, S. Gorbounov, J. Ferencei, M. Martisikova, V. Michels, S. Essenov, J. B. Dainton, M.-O. Boenig, T. Ravdandorj, Claus Kleinwort, A. Knutsson, Nicolas Berger, A. Makankine, P. Van Mechelen, Max Klein, G. Buschhorn, D. Ozerov, A. Zhelezov, S. Baudrand, T.H. Tran, Adrian Perieanu, P. A. Smirnov, Gerhard Brandt, V. Volchinski, H. Meyer, Xavier Janssen, A. Nikiforov, J-P. Meyer, Maxime Gouzevitch, Benno List, M. Brinkmann, V. Korbel, V. Lendermann, Magnus Hansson, M. Del Degan, A.-I. Lucaci-Timoce, C. Werner, L. Goerlich, L. Bystritskaya, G. Weber, H. Zohrabyan, U. Straumann, Laurent Schoeffel, B. Tseepeldorj, Karel Cerny, Matthew Beckingham, Anna Kropivnitskaya, R. Felst, and A. Glazov

Subjects
Physics, Nuclear and High Energy Physics, Particle physics, Jet (fluid), Neutral current, 010308 nuclear & particles physics, Scattering, High Energy Physics::Phenomenology, Four-momentum, Perturbative QCD, HERA, Deep inelastic scattering, 01 natural sciences, 7. Clean energy, Nuclear physics, Cross section (physics), 0103 physical sciences, High Energy Physics::Experiment, 010306 general physics
Abstract

Inclusive jet production is studied in neutral current deep-inelastic positron-proton scattering at large four momentum transfer squared Q^2>150 GeV^2 with the H1 detector at HERA. Single and double differential inclusive jet cross sections are measured as a function of Q^2 and of the transverse energy E_T of the jets in the Breit frame. The measurements are found to be well described by calculations at next-to-leading order in perturbative QCD. The running of the strong coupling is demonstrated and the value of alpha_s(M_Z) is determined. The ratio of the inclusive jet cross section to the inclusive neutral current cross section is also measured and used to extract a precise value for alpha_s(M_Z)=0.1193+/-0.0014(exp.)^{+0.0047}_{-0.0030}(th.)+/-0.0016(pdf).

Published
2007

30. Diffractive open charm production in deep-inelastic scattering and photoproduction at HERA

Author

S. Hussain, C. Grab, G. Thompson, H. Henschel, J.C. Bizot, G. Tsipolitis, Paul Laycock, E. Malinovski, Emmanuel Sauvan, G. Grindhammer, Judith Katzy, G. Cozzika, C. Schmitz, Hannes Jung, Alexander Zhokin, C. Vallée, W. Yan, Peter Robmann, A. M. Fomenko, E. Gabathuler, N. Loktionova, V. Jemanov, A. Hovhannisyan, Gero Flucke, M. Kapichine, M. Nozicka, H. Peng, I. Tsurin, G. Laštovička-Medin, B. Delcourt, D. Mladenov, Matthias Ulrich Mozer, Søren Schmidt, A. Baghdasaryan, A. Rostovtsev, A. Lebedev, A. Fedotov, Dusan Bruncko, M. Gouzevitch, K. B. Cantun Avila, S. Ginzburgskaya, C. Kiesling, A. De Roeck, F. Salvaire, E. Tzamariudaki, A. J. Campbell, D. Haidt, J. Feltesse, K. H. Hiller, R. C. W. Henderson, Laurent Schoeffel, Paul Newman, T. Zimmermann, A. Aktas, P. Baranov, B. Naroska, J. Cvach, M. Goettlich, D. Utkin, R.N. Shaw-West, A. Rimmer, C. Risler, C. Niebuhr, M. Fleischer, T. J. Sloan, Eram Rizvi, A. Dubak, P.J.W. Faulkner, G. Heinzelmann, A. Knutsson, Pavel Murin, K. Nowak, A.S. Belousov, T. Greenshaw, Sergey Rusakov, P. Truöl, Magnus Hansson, S. Egli, Y. Vazdik, B. List, M. Del Degan, V. Dodonov, Stefania Xella, S. Backovic, Th. D. Papadopoulou, M. Ibbotson, Y. Soloviev, Max Klein, G. Weber, C. Gwilliam, E. E. Elsen, U. Straumann, Thomas Naumann, Bogdan Povh, F. Sefkow, A. D.R. Vargas Trevino, J. Ferencei, Zuzana Rurikova, A. Astvatsatourov, Mila Pandurovic, K. Urban, M. Martisikova, Murrough Landon, A. Makankine, Erika Garutti, D. Wegener, Katerina Lipka, S. Ghazaryan, H. Lueders, G. Buschhorn, D. Ozerov, V. Tchoulakov, L. Goerlich, C. Wissing, Wolfgang Lange, V. Korbel, A. Specka, M. Sauter, E. Wünsch, R. Weber, Claus Kleinwort, P. A. Smirnov, M. Kraemer, Dave Sankey, S. M. Piec, Laurent Favart, M. Brinkmann, H. U. Martyn, J. Gayler, T. Anthonis, V. Efremenko, K. Müller, G. D. Patel, Matthew Beckingham, S. Gorbounov, T. Kluge, Stephen Maxfield, S. Mikocki, Biljana Antunović, G. Leibenguth, D.P. Johnson, T. Sykora, J. Stiewe, V. Chekelian, Anna Kropivnitskaya, E. Perez, Andrew Mehta, J. Bracinik, N. Gogitidze, R. Felst, I. Picuric, C. Pascaud, C. Werner, Guenter Eckerlin, André Schöning, J. V. Morris, Jenny List, A. W. Jung, M. Wessels, I. Sheviakov, P. E. Reimer, G. Herrera, Bradley Cox, A.J. Rahmat, A. Bunyatyan, A. Nikiforov, M. Jacquet, K. Krüger, R. Wolf, T. Frisson, Karel Cerny, J. Zálešák, P. Van Mechelen, L. Bystritskaya, V. Spaskov, S. Baudrand, K. Wacker, Ivan Smiljanic, I. Milcewicz-Mika, Anton Babaev, J. G. Contreras, A. Mohamed, P. Prideaux, A. Glazov, P. D. Thompson, V. Yeganov, H. Zohrabyan, A. Stoilov, Ll. Marti, I. Bozovic-Jelisavcic, L. Finke, R. Marshall, F. Moreau, S. J. Aplin, R. Plačakytė, Y.C. Zhu, S. Essenov, F. Zomer, K. Daum, V. Michels, J. B. Dainton, V. Andreev, V. Lendermann, A.-I. Lucaci-Timoce, G. Knies, Christian Helebrant, G. Franke, J. Žáček, Leif J. Jönsson, Benoit Roland, Hans-Christian Schultz-Coulon, T. Klimkovich, A. Falkewicz, Tomas Hreus, R. Eichler, F. Eisele, R. Oganezov, V. Cerny, B. Olivier, John A Coughlan, Grzegorz Nowak, A. Petrukhin, V. Brisson, E. Barrelet, T. Toll, E. A. De Wolf, Karlheinz Meier, R. Roosen, Y. de Boer, B. Stella, Stefan Schmitt, Vladimir Palichik, V. Lubimov, K. Nankov, L. N. Shtarkov, M.-O. Boenig, Zhen Zhang, Ricardo Lopez-Fernandez, S. Levonian, I. Panagoulias, M. Steder, S. Habib, Sakar Osman, D. Hoffmann, Andreas Meyer, Nicolas Berger, David South, A. Usik, J. Zimmermann, A. Eliseev, J. E. Olsson, A. Zhelezov, W. Bartel, J-P. Meyer, Malte Hildebrandt, F. W. Büsser, I. R. Kenyon, Natasa Raicevic, O. Behrendt, Vincent Boudry, S. Vinokurova, A. N. Morozov, P. Kostka, D. Perez-Astudillo, M. Gregori, J. Turnau, Adrian Perieanu, B. R. Grell, Gerhard Brandt, V. Volchinski, K. Begzsuren, H. Meyer, F. Tomasz, Xavier Janssen, I. Tsakov, T. N. Trinh, Roland Horisberger, A. Valkárová, K. Krastev, L. Lindfeld, D. Sunar, L. Lytkin, Cristinel Diaconu, Daniel Pitzl, D. Traynor, A. Asmone, F. Cassol-Brunner, M. Urban, Jan Kretzschmar, Andrej Liptaj, Pierre Marage, I. Glushkov, O. Behnke, Laboratoire de Physique Nucléaire et de Hautes Énergies (LPNHE), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de l'Accélérateur Linéaire (LAL), Université Paris-Sud - Paris 11 (UP11)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Laboratoire Leprince-Ringuet (LLR), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-École polytechnique (X)-Centre National de la Recherche Scientifique (CNRS), Centre de Physique des Particules de Marseille (CPPM), Aix Marseille Université (AMU)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Département d'Astrophysique, de physique des Particules, de physique Nucléaire et de l'Instrumentation Associée (DAPNIA), Commissariat à l'énergie atomique et aux énergies alternatives (CEA), H1, (ukupan broj autora: 294), Centre National de la Recherche Scientifique (CNRS)-Université Paris Diderot - Paris 7 (UPD7)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Pierre et Marie Curie - Paris 6 (UPMC), Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris-Sud - Paris 11 (UP11), and Centre National de la Recherche Scientifique (CNRS)-École polytechnique (X)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)

Subjects
Physics, Quantum chromodynamics, Particle physics, Physics and Astronomy (miscellaneous), Meson, 010308 nuclear & particles physics, High Energy Physics::Phenomenology, Hadron, FOS: Physical sciences, Parton, HERA, Deep inelastic scattering, 01 natural sciences, High Energy Physics - Experiment, Charm quark, Nuclear physics, High Energy Physics - Experiment (hep-ex), 0103 physical sciences, [PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex], ddc:530, High Energy Physics::Experiment, Rapidity, Nuclear Experiment, 010306 general physics, Engineering (miscellaneous)
Abstract

Measurements are presented of diffractive open charm production at HERA. The event topology is given by ep -> eX Y where the system X contains at least one charmed hadron and is well separated by a large rapidity gap from a leading low-mass proton remnant system Y. Two analysis techniques are used for the cross section measurements. In the first, the charm quark is tagged by the reconstruction of a D*(2010) meson. This technique is used in deep-inelastic scattering (DIS) and photoproduction. In the second, a method based on the displacement of tracks from the primary vertex is used to measure the open charm contribution to the inclusive diffractive cross section in DIS. The measurements are compared with next-to-leading order QCD predictions based on diffractive parton density functions previously obtained from a QCD analysis of the inclusive diffractive cross section at H1. A good agreement is observed in the full kinematic regime, which supports the validity of QCD factorization for open charm production in diffractive DIS and photoproduction., 39 pages, 13 figures, 8 tables

Published
2007

31. Search for a narrow baryonic resonance decaying toKs0porKs0p¯in deep inelastic scattering at HERA

Author

S. Levonian, A. M. Fomenko, Pierre Marage, Peter Robmann, Stephen Maxfield, C. Gerlich, Paul Laycock, L. Finke, B. Olivier, I. Glushkov, F. Zomer, H-C. Schultz-Coulon, J. Stiewe, Zhen Zhang, D. P. C. Sankey, Y.C. Zhu, K. Daum, Ricardo Lopez-Fernandez, E. Malinovski, Emmanuel Sauvan, G. Grindhammer, Magnus Hansson, M. Del Degan, C. Wissing, Andrew Mehta, J. Bracinik, Ewelina Lobodzinska, Matthew Beckingham, P. Baranov, M. Steder, D. Hoffmann, T. Zimmermann, L. Goerlich, Anna Kropivnitskaya, Roland Horisberger, A. Valkárová, R. Felst, N. Gogitidze, A. Usik, G. Cozzika, T. Toll, V. Michels, W.D. Dau, J. B. Dainton, G. Knies, H. Peng, V. Andreev, S. Backovic, Thorsten Lux, C. Niebuhr, L. Janauschek, David South, T. Kluge, O. Behnke, D. Mladenov, B. R. Grell, S. Egli, V. Jemanov, F. Tomasz, Matthias Ulrich Mozer, J. Zimmermann, H. Lueders, K. Krüger, C. Schmitz, C. Pascaud, T. J. Sloan, P.J.W. Faulkner, A.S. Belousov, Hannes Jung, Alexander Zhokin, Y. Soloviev, Sergey Rusakov, P. Truöl, V. Lubimov, Dusan Bruncko, J. Becker, C. Vallée, Guenter Eckerlin, E. Barrelet, Z. Rurikova, A. Fedotov, A. W. Jung, B. Naroska, D. Sunar, B. Stella, D. Lüke, Stefan Schmitt, S. Baumgartner, P. E. Reimer, S. Ginzburgskaya, Søren Schmidt, C. Kiesling, A. De Roeck, E. Tzamariudaki, A. J. Campbell, K. Krastev, G. Herrera, Bradley Cox, Laurent Schoeffel, A. Dubak, K. H. Hiller, R. C. W. Henderson, G. Leibenguth, Sakar Osman, M. Jacquet, L. Lindfeld, W. Yan, T. Greenshaw, Christoph Grab, Erika Garutti, R. Wolf, K. Urban, K. Nankov, L. N. Shtarkov, E. Wünsch, A. Eliseev, C. Veelken, E. A. De Wolf, Karlheinz Meier, R. Roosen, Anton Babaev, N. Loktionova, J. E. Olsson, W. Bartel, S. Hussain, J. Ferencei, M. Martisikova, G. Thompson, Adrian Perieanu, S. Gorbounov, L. Lytkin, A. Specka, Malte Hildebrandt, Cristinel Diaconu, Vladimir Palichik, J. G. Contreras, A. Mohamed, Georgios Tsipolitis, M. Fleischer, T. Frisson, G. Weber, U. Straumann, A. Aktas, I. Milcewicz-Mika, G. Franke, P. Prideaux, A. Hovhannisyan, Claus Kleinwort, Th. Naumann, J. Žáček, A. Baghdasaryan, A. Rostovtsev, Daniel Pitzl, Wolfgang Lange, R. Weber, F. W. Büsser, O. Behrendt, S. Vinokurova, Y. de Boer, J. Feltesse, J. Gayler, V. Yeganov, D. Traynor, I. Tsurin, Ilias Panagoulias, A. Asmone, F. Moreau, S. J. Aplin, H. Henschel, F. Cassol-Brunner, Bogdan Povh, P. Kostka, F. Sefkow, L. Bystritskaya, J.C. Bizot, P. Van Mechelen, Natasa Raicevic, S. Baudrand, Leif J. Jönsson, Benoit Roland, V. Chekelian, L. Hajduk, D. Utkin, E. Gabathuler, M. Urban, B. List, J. Turnau, B. Portheault, H. U. Martyn, Matthias Klein, Theodora Papadopoulou, S. Essenov, M. Ismail, M. Kapichine, M. Nozicka, Vincent Boudry, Gerhard Brandt, John A Coughlan, E. E. Elsen, I. Tsakov, A. N. Morozov, H. Zohrabyan, D. Perez-Astudillo, M. Gregori, David Milstead, P. A. Smirnov, R. Plačakytė, A. Schöning, E. Rizvi, G. D. Patel, Jan Kretzschmar, B. Delcourt, V. Volchinski, Andrej Liptaj, S. Ghazaryan, Paul Richard Newman, Grzegorz Nowak, Pavel Murin, M. Ibbotson, T. Klimkovich, I. Sheviakov, S. Schätzel, Biljana Antunović, Katerina Lipka, A. Falkewicz, H. Meyer, Emmanuelle Perez, Karel Cerny, Laurent Favart, V. Tchoulakov, R.N. Shaw-West, A. Petrukhin, T. Anthonis, J. Zálešák, Xavier Janssen, V. Spaskov, D.P. Johnson, K. Wacker, A. B. Meyer, Tomas Hreus, R. Eichler, A. Glazov, V. Korbel, Y. Vazdik, N. Malden, I. R. Kenyon, A. Stoilov, G. Laštovička-Medin, Michael R. Wessels, V. Brisson, P.D. Thompson, Stefania Xella, C. Werner, A. Rimmer, J. V. Morris, Jenny List, A. Knutsson, A. Makankine, A.J. Rahmat, A. Bunyatyan, Ll. Marti, G. Buschhorn, D. Ozerov, V. Lendermann, F. Eisele, M.-O. Boenig, S. Mangano, A. Nikiforov, R. Oganezov, Nicolas Berger, R. Marshall, A. Zhelezov, A. Lebedev, F. Salvaire, D. Haidt, A.-I. Lucaci-Timoce, G. Heinzelmann, V. Dodonov, A. D.R. Vargas Trevino, V. Cerny, G. Flucke, Jean-Arcady Meyer, C. Risler, C. Gwilliam, M. P. J. Landon, A. Astvatsatourov, Judith Katzy, B. Wessling, K. Müller, J. Cvach, K. Nowak, M. Goettlich, D. Wegener, V. Efremenko, and S. Mikocki

Subjects
Physics, Nuclear and High Energy Physics, Particle physics, 010308 nuclear & particles physics, Scattering, Resonance, Sigma, HERA, Deep inelastic scattering, 01 natural sciences, Pentaquark, Baryon, Nuclear physics, 0103 physical sciences, High Energy Physics::Experiment, 010306 general physics, Bar (unit)
Abstract

A search for a narrow baryonic resonance decaying to K(s)(0)p or K-s(0)(p) over bar is carried out in deep inelastic ep scattering with the H1 detector at HERA. ss Such a resonance could be a strange pentaquark Theta(+), evidence for which has been reported by several experiments. The K(s)(0)p and K-s(0)(p) over bar invariant ss mass distributions presented here do not show any significant peak in the mass range from threshold up to 1.7 GeV. Mass dependent upper limits on sigma(ep -> e Theta X+) x BR(Theta(+) -> K(0)p) are obtained at the 95% confidence level.

Published
2006

32. Púrpura fulminante posvaricelosa

Author

T. Toll Costa, C. Luaces Cubells, J.J. García García, S. Zambudio Sert, L. Alsina Manrique de Lara, and A. Pizà Oliveras

Subjects
Pathology, medicine.medical_specialty, Antiprotein S antibodies, Chickenpox, biology, business.industry, Autoantibody, Consumption Coagulopathy, Varicella, medicine.disease, Pediatrics, RJ1-570, Protein S, Coagulation, Purpurafulminans, Pediatrics, Perinatology and Child Health, biology.protein, Medicine, Antibody, business, Complication, Purpura fulminans
Abstract

La púrpura fulminante es una complicación rara de la varicela que se caracteriza por la aparición progresiva de lesiones purpúricas o equimóticas dolorosas asociado a una alteración analítica propia de una coagulopatía de consumo. La activación de la coagulación es debida a un descenso marcado y prolongado de la proteína S, que probablemente es secundario a la formación de anticuerpos antiproteína S. El mecanismo responsable de la síntesis de estos autoanticuerpos es desconocido. Se presentan 3 casos de púrpura fulminante posvaricelosa y se revisan las características clinicoanalíticas y las recomendaciones diagnosticoterapéuticas actuales de esta entidad : Purpura fulminans (PF) is an infrequent complication of varicella characterized by the progressive development of purpuric or painful ecchymotic lesions associated with biochemical alternations typical of consumption coagulopathy. Activation of coagulation is due to a marked and prolonged decrease in protein S, which is probably secondary to the formation of antiprotein S antibodies. The mechanism responsible for the synthesis of these autoantibodies is unknown. We present three cases of postvaricella PF and review the clinical and biochemical characteristics of this entity, as well as current diagnostic and therapeutic recommendations

Published
2004

33. Immune tolerance induction in haemophilia A patients with inhibitors by treatment with recombinant factor VIII: a retrospective non-interventional study

Author

C. Rothschild, K. Achilles, G. E. Rivard, and T. Toll

Subjects
Male, medicine.medical_specialty, Sucrose, Time Factors, Haemophilia A, Bethesda unit, Haemophilia, Hemophilia A, Recombinant factor viii, Immune tolerance, Maintenance therapy, Internal medicine, medicine, Immune Tolerance, Humans, Adverse effect, Child, Genetics (clinical), Retrospective Studies, Factor VIII, Blood Coagulation Factor Inhibitors, business.industry, Infant, Retrospective cohort study, Hematology, General Medicine, medicine.disease, Surgery, Child, Preschool, business, Follow-Up Studies
Abstract

Immune tolerance induction (ITI) can overcome inhibitory factor VIII (FVIII) antibodies in haemophilia A patients receiving FVIII replacement therapy. The objective was to evaluate the use of sucrose-formulated, full-length recombinant FVIII (rFVIII-FS) for ITI therapy. Patients (8 years at ITI start) with severe haemophilia A and a peak inhibitor titre5 Bethesda units (BU) who underwent ITI with any rFVIII-FS dose for ≥ 9 months (or until success) were eligible for this retrospective study. Efficacy analyses included descriptions of ITI treatment regimens and outcomes; ITI success was determined solely at the discretion of the investigator. Safety analyses included assessment of adverse events. Of 51 enrolled patients, 32 [high dose (≥ 85 IU kg(-1) day(-1)), n = 21; low dose, n = 11] were eligible for analysis. ITI was successful in 69% (22/32) of patients (high dose, 66.7%; low dose, 72.7%) after a median of 1.4 years (range, 0.1-3.6 years). Influencing factors for ITI success were start of ITI1 year after inhibitor detection and an inhibitor titre10 BU at ITI start. All patients successfully tolerized with ITI continued to receive rFVIII-FS prophylaxis as maintenance therapy, with no inhibitor recurrence from the end of ITI until study enrolment. Use of rFVIII-FS for ITI was effective and well tolerated; success rates were similar to those in published studies.

Published
2013

34. [Protocol for the study and treatment of immune thrombocytopenic purpura (ITP). ITP-2010]

Author

E, Monteagudo, R, Fernández-Delgado, A, Sastre, T, Toll, A, Llort, J, Molina, I, Astigarraga, M A, Dasí, and A, Cervera

Subjects
Clinical Protocols, Purpura, Thrombocytopenic, Decision Trees, Humans
Abstract

Primary immune thrombocytopenia (ITP), formerly known as immune thrombocytopenic purpura, is a disease in which clinical and therapeutic management has always been controversial. The ITP working group of the Spanish Society of Paediatric Haematology and Oncology has updated its guidelines for diagnosis and treatment of ITP in children based on current guidelines, literature review, clinical trials and member consensus. The primary objective was to lessen clinical variability in diagnostic and therapeutic procedures in order to obtain best clinical results with minimal adverse events and good quality of life.

Published
2010

35. Search for lepton flavour violation in ep collisions at HERA

Author

S. Levonian, Laurent Schoeffel, K. Urban, Murrough Landon, Judith Katzy, S. Habib, Zhen Zhang, S. Gorbounov, Ricardo Lopez-Fernandez, Adrian Perieanu, F. Eisele, Sakar Osman, R. Oganezov, B. Tseepeldorj, Gerhard Brandt, P. Van Mechelen, V. Volchinski, H. Meyer, E. Barrelet, A. Eliseev, Xavier Janssen, K. Müller, I. Panagoulias, M. Steder, D. Hoffmann, Andreas Meyer, A. Usik, V. Cerny, B. Olivier, P. D. Thompson, V. Yeganov, F. Moreau, S. J. Aplin, E. A. De Wolf, Karlheinz Meier, R. Roosen, R.N. Shaw-West, J. E. Olsson, W. Bartel, M. Brinkmann, T. N. Trinh, L. Finke, Y.C. Zhu, J. V. Morris, Jenny List, Stephen Maxfield, M.-O. Boenig, M. Goettlich, F. Zomer, H. U. Martyn, Y. de Boer, S. Hussain, C. Grab, K. Daum, G. Thompson, Malte Hildebrandt, F. W. Büsser, S. Essenov, G. Leibenguth, B. List, V. Andreev, A.J. Rahmat, A. Bunyatyan, I. R. Kenyon, Daniel Pitzl, Natasa Raicevic, Nicolas Berger, G. Knies, Vincent Boudry, Grzegorz Nowak, I. Sheviakov, Katerina Lipka, V. Tchoulakov, V. Lubimov, J. Zimmermann, D. Traynor, A. Asmone, A. D.R. Vargas Trevino, H. Henschel, J. Stiewe, J.C. Bizot, Andrew Mehta, J. Bracinik, K. H. Hiller, Roland Horisberger, N. Gogitidze, A. Valkárová, R. C. W. Henderson, A. N. Morozov, A. Makankine, D. Perez-Astudillo, M. Gregori, Christian Helebrant, A. Petrukhin, K. Krüger, Pavel Murin, M. Jacquet, A. Zhelezov, J-P. Meyer, Paul Laycock, E. Malinovski, Th. D. Papadopoulou, G. Buschhorn, B. R. Grell, David M. South, Matthew Beckingham, F. Cassol-Brunner, T. Frisson, F. Tomasz, D. Ozerov, G. Franke, D. Wegener, C. Risler, R. Weber, J. Žáček, Emmanuel Sauvan, Anna Kropivnitskaya, R. Felst, J. Zálešák, M. Kapichine, M. Nozicka, I. Milcewicz-Mika, K. Nankov, E. Wünsch, Dave Sankey, A. Specka, E. Perez, Wolfgang Lange, Hans-Christian Schultz-Coulon, V. Spaskov, G. Grindhammer, V. Jemanov, L. N. Shtarkov, B. Delcourt, J. Gayler, O. Behrendt, S. Vinokurova, K. Wacker, V. Efremenko, A. Baghdasaryan, G. D. Patel, K. Krastev, Jan Kretzschmar, A. W. Jung, Andrej Liptaj, V. Brisson, Laurent Favart, P. E. Reimer, A. Astvatsatourov, P. Kostka, M. Fleischer, Leif J. Jönsson, E. Gabathuler, A. Rostovtsev, Benoit Roland, S. Mikocki, A. Falkewicz, Mila Pandurovic, J. Turnau, Biljana Antunović, L. Lindfeld, D. Mladenov, Pierre Marage, D.P. Johnson, Dusan Bruncko, T. Sykora, Tomas Hreus, R. Eichler, Magnus Hansson, S. Baudrand, M. Wessels, T. Klimkovich, G. Herrera, R. Wolf, B. Naroska, M. Del Degan, K. Begzsuren, M. E. Janssen, Peter Robmann, T. Toll, T. Anthonis, I. Glushkov, I. Tsakov, A. Aktas, T. Greenshaw, V. Michels, G. Cozzika, J. B. Dainton, D. Utkin, C. Niebuhr, O. Behnke, L. Goerlich, Ll. Marti, J. Ferencei, M. Martisikova, J. Feltesse, A. Lebedev, I. Bozovic-Jelisavcic, T. Ravdandorj, S. Egli, S. Backovic, C. Schmitz, Hannes Jung, D. Sunar, F. Salvaire, Claus Kleinwort, D. Haidt, Bogdan Povh, F. Sefkow, M. Kraemer, Max Klein, Alexander Zhokin, G. Laštovička-Medin, Zuzana Rurikova, Y. Soloviev, H. Lueders, J. Cvach, H. Peng, C. Vallée, S. Schmidt, M. Sauter, V. Chekelian, T. J. Sloan, Eram Rizvi, A. Rimmer, John A Coughlan, A. Cholewa, P. A. Smirnov, L. Lytkin, K. Nowak, Matthias Ulrich Mozer, Cristinel Diaconu, G. Heinzelmann, A. Knutsson, T. Kluge, V. Dodonov, A. Fedotov, B. Stella, A. Nikiforov, Stefan Schmitt, K. B. Cantun Avila, S. Ginzburgskaya, I. Picuric, C. Pascaud, C. Kiesling, Vladimir Palichik, A. De Roeck, E. Tzamariudaki, A. J. Campbell, Guenter Eckerlin, André Schöning, G. Tsipolitis, A. Dubak, R. Plačakytė, Y. Vazdik, A. M. Fomenko, Stefania Xella, Ivan Smiljanic, Anton Babaev, J. G. Contreras, A. Mohamed, P. Prideaux, L. Bystritskaya, H. Zohrabyan, V. Lendermann, A.-I. Lucaci-Timoce, C. Wissing, V. Korbel, Calin Alexa, S. Ghazaryan, M. Gouzevitch, C. Werner, Paul Newman, T. Zimmermann, G. Weber, U. Straumann, Thomas Naumann, Erika Garutti, Karel Cerny, A. Glazov, W. Yan, N. Loktionova, A. Hovhannisyan, T. Preda, I. Tsurin, P. Baranov, P.J.W. Faulkner, A.S. Belousov, Sergey Rusakov, P. Truöl, E. E. Elsen, S. M. Piec, (ukupan broj autora: 293), Laboratoire de Physique Nucléaire et de Hautes Énergies (LPNHE), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de l'Accélérateur Linéaire (LAL), Université Paris-Sud - Paris 11 (UP11)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Laboratoire Leprince-Ringuet (LLR), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-École polytechnique (X)-Centre National de la Recherche Scientifique (CNRS), Centre de Physique des Particules de Marseille (CPPM), Aix Marseille Université (AMU)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Département d'Astrophysique, de physique des Particules, de physique Nucléaire et de l'Instrumentation Associée (DAPNIA), Commissariat à l'énergie atomique et aux énergies alternatives (CEA), H1, Centre National de la Recherche Scientifique (CNRS)-Université Paris Diderot - Paris 7 (UPD7)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Pierre et Marie Curie - Paris 6 (UPMC), Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris-Sud - Paris 11 (UP11), and Centre National de la Recherche Scientifique (CNRS)-École polytechnique (X)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)

Subjects
Physics, Particle physics, Muon, Luminosity (scattering theory), Physics and Astronomy (miscellaneous), 010308 nuclear & particles physics, Hadron, Flavour, High Energy Physics::Phenomenology, FOS: Physical sciences, HERA, Jet (particle physics), Lambda, 01 natural sciences, High Energy Physics - Experiment, Nuclear physics, High Energy Physics - Experiment (hep-ex), 0103 physical sciences, [PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex], ddc:530, High Energy Physics::Experiment, 010306 general physics, Nuclear Experiment, Engineering (miscellaneous), Lepton
Abstract

A search for the lepton flavour violating processes ep→μX and ep→τX is performed with the H1 experiment at HERA. Final states with a muon or tau and a hadronic jet are searched for in a data sample corresponding to an integrated luminosity of 66.5 pb-1 for e+p collisions and 13.7 pb-1 for e-p collisions at a centre-of-mass energy of 319 GeV. No evidence for lepton flavour violation is found. Limits are derived on the mass and the couplings of leptoquarks inducing lepton flavour violation in an extension of the Buchmüller–Rückl–Wyler effective model. Leptoquarks produced in ep collisions with a coupling strength of λ=0.3 and decaying with the same coupling strength to a muon–quark pair or a tau–quark pair are excluded at 95% confidence level up to masses of 459 GeV and 379 GeV, respectively., The European Physical Journal C, 52 (4), ISSN:1434-6044, ISSN:1434-6052

Published
2007

36. Assessment of neutrophil activation in whole blood by flow cytometry

Author

T Toll, Jesús Estella, A Alvarez-Larrán, and Susana Rives

Subjects
Male, Neutrophils, Clinical Biochemistry, Sensitivity and Specificity, Neutrophil Activation, Flow cytometry, Leukocyte Adhesion Deficiency Type 1, Chronic granulomatous disease, medicine, Humans, Child, Whole blood, Respiratory Burst, CD11b Antigen, Hematologic Tests, medicine.diagnostic_test, biology, Dose-Response Relationship, Drug, Chemistry, Biochemistry (medical), Infant, Hematology, General Medicine, medicine.disease, Flow Cytometry, Respiratory burst, Dose–response relationship, Integrin alpha M, Child, Preschool, Immunology, biology.protein, Absolute neutrophil count, Tetradecanoylphorbol Acetate, Female
Abstract

Flow cytometry methods currently used for measuring neutrophil activation involve sample manipulation, which may result in cellular depletion and artifactual activation. To design a new methodology for measurement of neutrophil activation with minimal sample manipulation. Oxidative burst and CD 11b neutrophil expression were simultaneously assessed by a new no-lyse no-wash technique and a standard lyse-method in 10 pediatric patients with recurrent infections and two patients with chronic granulomatous disease (CGD). The new technique was based on nucleic acid staining to discriminate erythrocytes and debris without requiring physical separation. Both methods served equally to confirm or eliminate the diagnosis of CGD and leukocyte adhesion deficiency type 1. The values of baseline CD11b and oxidative burst obtained using the lysis method were significantly higher than those obtained by the no-lyse no-wash method. After activation, the lysis method resulted in higher neutrophil depletion (41%vs. 19%, P = 0.03). When compared with standard methods, neutrophil activation assessment by a no-lyse no-wash method resulted in lower neutrophil depletion and differences in oxidative burst and CD11b neutrophil values.

Published
2005

37. [Postvaricella purpura fulminans]

Author

L, Alsina Manrique de Lara, S, Zambudio Sert, A, Pizà Oliveras, T, Toll Costa, J J, García García, and C, Luaces Cubells

Subjects
Male, Chickenpox, IgA Vasculitis, Child, Preschool, Humans, Female, Child, Antibodies, Autoantibodies, Protein S
Abstract

Purpura fulminans (PF) is an infrequent complication of varicella characterized by the progressive development of purpuric or painful ecchymotic lesions associated with biochemical alternations typical of consumption coagulopathy. Activation of coagulation is due to a marked and prolonged decrease in protein S, which is probably secondary to the formation of antiprotein S antibodies. The mechanism responsible for the synthesis of these autoantibodies is unknown. We present three cases of postvaricella PF and review the clinical and biochemical characteristics of this entity, as well as current diagnostic and therapeutic recommendations.

Published
2004

38. [Autoimmune hemolytic anemia with complement-positive direct antiglobulin test]

Author

S, Martínez Nadal, I, Alcorta Loyola, J, Estella Aguado, S, Rives Sola, and T, Toll Costa

Subjects
Male, Coombs Test, Adolescent, Child, Preschool, Immunoglobulin G, Humans, Female, Anemia, Hemolytic, Congenital, Antibodies, Anti-Idiotypic, Autoimmune Diseases
Abstract

Autoimmune hemolytic anemia (AIHI) is an infrequent disease in the pediatric age group. Its diagnosis is given by the direct antiglobulin test (DAT) or Coombs' test, which determines which type of globulin (IgG or complement) is the cause of the hemolysis. The type of globulin involved determines the etiology of AIHI, which is usually confirmed by positive results of other laboratory investigations such as cold agglutinin determination or the Donath-Landsteiner test. We present three cases of AIHI. DAT was positive to complement with diverse etiology: warm antibody with IgG-negative DAT, cold agglutinins associated with infectious mononucleosis, and Doth-Landsteiner antibodies. In all patients, empirical treatment with corticosteroids was initiated. The treatment was withdrawn or continued, depending on the final etiology of AIHI.

Published
2003

39. Safety and efficacy of high-dose G-CSF (24 microg/kg) alone for PBSC moblization in children

Author

Jesús Estella, I Alcorta, T Toll, Susana Rives, E Tuset, and B Pérez-Dueñas

Subjects
Oncology, Male, medicine.medical_specialty, Adolescent, Filgrastim, Treatment outcome, Internal medicine, Neoplasms, Granulocyte Colony-Stimulating Factor, medicine, Humans, Leukapheresis, Child, Hematopoietic Stem Cell Mobilization, Transplantation, business.industry, Hematology, Recombinant Proteins, Blood Cell Count, Treatment Outcome, Child, Preschool, Drug Evaluation, Female, Safety, business, medicine.drug
Published
2002

40. Cultures of myeloid progenitor cells in pediatric essential thrombocythemia

Author

T Toll, Woessner S, Blanca Espinet, Sergi Serrano, P Bastida, JJ Ortega, Carlos Besses, Lurdes Zamora, Lourdes Florensa, P Mayayo, and F. Solé

Subjects
Male, Cancer Research, Myeloid Progenitor Cells, Adolescent, business.industry, Essential thrombocythemia, Cell Culture Techniques, Hematology, medicine.disease, Oncology, Child, Preschool, Cancer research, Medicine, Humans, Female, business, Child, Thrombocythemia, Essential
Published
2002

41. [Microangiopathic hemolytic anemia and thrombocytopenia. Thrombotic thrombocytopenic purpura]

Author

R, Garrido, J, Estella Aguado, T, Toll, I, Alcorta, and M, Mateo

Subjects
Male, Anemia, Hemolytic, Purpura, Thrombotic Thrombocytopenic, Vincristine, Child, Preschool, Remission, Spontaneous, Humans, Female, Plasmapheresis, Child, Thrombocytopenia
Abstract

Thrombotic thrombocytopenic purpura (TTP) or Moschovitz' syndrome is rare and is even rarer in childhood. Clinically, it is characterized by microangiopathic hemolytic anemia, thrombocytopenia, neurologic abnormalities, fever and renal dysfunction. The etiology is still unknown, although different factors such as large von Willebrand factor multimers and prostacyclin have been implicated. The acute form is more frequent, and in most cases the course is fulminant if treatment is not initiated. Laboratory data typically reveal hemolytic anemia, with schistocytes on the peripheral smear, diminished serum haptoglobin, and thrombocytopenia.We present the clinical cases of two children, aged 4 and 7 respectively, with TTP, but with different evolution and treatment. Evolution was favorable in both patients. The first child recovered spontaneously. In the second plasmapheresis was required and produced remission of all the symptomatology. Normality has been maintained for 36 and 24 months respectively, and the children have presented no clinico-biological alterations.

Published
2001

43. [G-CSF treatment in a case of Kostmann's infantile congenital neutropenia]

Author

A M, Pastor Gómez, J, Estella Aguado, T, Toll Costa, M, Mateo Moraja, G, Romera Modamio, and I, Alcorta Loyola

Subjects
Male, Neutropenia, Time Factors, Bone Density, Granulocyte Colony-Stimulating Factor, Humans, Infant, Bone Marrow Cells, Syndrome, Cells, Cultured
Published
1998

44. Case Forum: Juvenile myelomonocytic leukemia

Author

Susana Rives, C.M. Niemeyer, M. Perez-Iribarne, I Alcorta, Jesús Estella, E Tuset, and T Toll

Subjects
Cancer Research, Oncology, Juvenile myelomonocytic leukemia, business.industry, Immunology, Medicine, Hematology, business, medicine.disease
Published
2006

45. Large volume leukapheresis for peripheral blood stem cell collection in children under 10 kg in weight

Author

I Martin, E Tuset, Susana Rives, A Albert, Jesús Estella, I Alcorta, and T Toll

Subjects
Transplantation, medicine.medical_specialty, Blood Volume, business.industry, Body Weight, Hematopoietic Stem Cell Transplantation, Infant, Hematology, Hematopoietic Stem Cells, Surgery, Peripheral blood stem cell collection, Child, Preschool, medicine, Humans, Leukapheresis, Large volume leukapheresis, business
Abstract

Large volume leukapheresis for peripheral blood stem cell collection in children under 10 kg in weight

Published
2003

46. Protocolo de estudio y tratamiento de la trombocitopenia inmune primaria (PTI-2010)

Author

Aurea Cervera, Itziar Astigarraga, Emilio Monteagudo, Ana Sastre, T Toll, A. Llort, J. Molina, María Angeles Dasí, and Rafael Fernández-Delgado

Subjects
Protocol (science), medicine.medical_specialty, business.industry, MEDLINE, Disease, medicine.disease, Pediatrics, Thrombocytopenic purpura, RJ1-570, Clinical trial, Immune system, Immune thrombocytopenic purpura, Quality of life, immune system diseases, hemic and lymphatic diseases, Pediatrics, Perinatology and Child Health, ITP, Medicine, business, Adverse effect, Intensive care medicine, Primary immune thrombocytopenia, Children
Abstract

Resumen: La trombocitopenia inmune primaria, anteriormente conocida como púrpura trombocitopénica inmune, es una enfermedad cuyo manejo diagnóstico y terapéutico ha sido siempre controvertido. La Sociedad Española de Hematología y Oncología Pediátricas, a través del grupo de trabajo de la PTI, ha actualizado el documento con las recomendaciones protocolizadas para el diagnóstico y tratamiento de esta enfermedad, basándose en las guías clínicas disponibles actualmente, revisiones bibliográficas, ensayos clínicos y el consenso de sus miembros. El objetivo principal es disminuir la variabilidad clínica en los procedimientos diagnósticos y terapéuticos con el fin de obtener los mejores resultados clínicos, con menor incidencia en la calidad de vida y los mínimos efectos adversos. Abstract: Primary immune thrombocytopenia (ITP), formerly known as immune thrombocytopenic purpura, is a disease in which clinical and therapeutic management has always been controversial. The ITP working group of the Spanish Society of Paediatric Haematology and Oncology has updated its guidelines for diagnosis and treatment of ITP in children based on current guidelines, literature review, clinical trials and member consensus. The primary objective was to lessen clinical variability in diagnostic and therapeutic procedures in order to obtain best clinical results with minimal adverse events and good quality of life.

Published
2011

47. [Purpura fulminans]

Author

T, Toll i Costa, J, Estella Aguado, W, Youssef Fafheh, and J, Bello Mayoraz

Subjects
Aminocaproates, Male, IgA Vasculitis, Humans, Plasmapheresis, Child
Published
1992

48. Mutación del factor V de Leiden como causa de trombosis venosa

Author

J M Martín, Z Lobato-Salinas, T Toll-Costa, F J Cambra-Lasaosa, M Pons-Odena, Jaime Campistol, and A Palomeque-Rico

Subjects
Gynecology, medicine.medical_specialty, Venous thrombosis, business.industry, medicine, Neurology (clinical), General Medicine, Factor V Leiden mutation, medicine.disease, business
Abstract

Introduccion. La trombosis venosa (TV) es una patologia poco frecuente en Pediatria. Se han descrito un gran numero de factores de riesgo protrombotico. Las alteraciones de la coagulacion se presentan en mas de la mitad de los ninos con accidente cerebrovascular. La mutacion del factor V de Leiden (FVL) destaca como una de las causas geneticas mas comunes de TV profunda en ninos y adultos de raza caucasica, y representa un 20-25% segun las series. Caso clinico. Nina de 2 anos con enfermedad hipoxicoisquemica y sindrome de West, que presenta una TV profunda de ambas extremidades inferiores. El cuadro evoluciona hacia gangrena y precisa escariectomia y amputacion del 2.o, 3.o y 4.o dedos del pie izquierdo; ademas, se desarrolla un infarto hemorragico intraparenquimatoso frontoparietal derecho con extension hematica tetraventricular e hidrocefalia, que precisa la colocacion de un drenaje ventricular externo y, posteriormente, una valvula de derivacion ventriculoperitoneal. Conclusiones. En el estudio de la coagulacion se confirma la mutacion del FVL en la paciente y el estudio practicado a los progenitores demostro la misma mutacion en el padre. El riesgo de recurrencia y la gravedad de la TV obligan al tratamiento antiagregante de por vida, que actualmente realiza con acido acetilsalicilico

Published
2004

49. Trombosis venosa cerebral en niña portadora de la mutación 20210G®A del gen de la protrombina, tratada mediante fibrinólisis local del seno sagital superior

Author

Guimaraens-Martínez L, Jaime Campistol, Vivas-Díaz E, Perez Dueñas B, A Noguera-Julian, Cambra Lasaosa Fj, T Toll-Costa, and A Palomeque-Rico

Subjects
Coma, Urokinase, medicine.medical_specialty, business.industry, medicine.medical_treatment, General Medicine, medicine.disease, Thrombosis, Sagittal plane, Surgery, Venous thrombosis, medicine.anatomical_structure, Fibrinolysis, medicine, Neurology (clinical), medicine.symptom, business, medicine.drug, Superior sagittal sinus, Paresis
Abstract

Case report Girl, aged 4, without antecedents who was admitted to our hospital for drowsiness and progressive sensorial depression. Within 24 hours the clinical picture deteriorated with partial seizures of the right hand side of the body and right hemiparesis. A brain CAT scan showed a left temporoparietal parenchymatous haematoma with collapse of the left lateral ventricle and moderate obliteration of the basal cisterns. MR angiography and cerebral arteriography displayed images that were compatible with thrombosis of the superior sagittal, the left transverse and the sigmoid sinuses. The patient was heterozygotic for the G A mutation in position 20210 of the prothrombin gene, which is linked with a high risk of thrombosis. She was given heparin intravenously, but continued to display endocranial hypertension and tissue ischemia with partial response to hyperosmolar agents and barbituric coma. She was therefore submitted to selective catheterization of the superior sagittal sinus and continuous local fibrinolysis with urokinase for 72 hours. The outcome was satisfactory, with repermeabilisation of the thrombosed sinuses and a good clinical response with no complications. At present the patient has functional paresis of the right hand and receives treatment with oral anticoagulants. Conclusions We advocate the use of early local fibrinolytic treatment with urokinase in children affected by thrombosis of the venous sinuses who do not respond to treatment with sodium heparin. We consider it necessary to include the molecular study of the G20210A mutation of the prothrombin gene in screening for prothrombotic risk factors in small children

Published
2002

50. [Factor V deficiency; apropos of a case]

Author

E, Hernández Pérez, J, Carnicer de la Pardina, R M, Badía Torrella, M, Melo Valls, M A, Comas Sans, and M T, Toll Costa

Subjects
Diagnosis, Differential, Male, Child, Preschool, Humans, Pain, Hemorrhage, Factor V Deficiency, Joint Diseases, Purpura
Published
1989

Catalog

Books, media, physical & digital resources
See catalog results