Benoît Perthame, Noemi David, Laboratoire Jacques-Louis Lions (LJLL (UMR_7598)), Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), Modelling and Analysis for Medical and Biological Applications (MAMBA), Inria de Paris, Institut National de Recherche en Informatique et en Automatique (Inria)-Institut National de Recherche en Informatique et en Automatique (Inria)-Laboratoire Jacques-Louis Lions (LJLL (UMR_7598)), Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), European Project: 740623,H2020 Pilier ERC,ADORA(2017), European Project: 754362,MathInParis, Université Paris Diderot - Paris 7 (UPD7)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Université Paris Diderot - Paris 7 (UPD7)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Diderot - Paris 7 (UPD7)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), European Project: 754362,MathInParis(2017), Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris, and Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris
International audience; Both compressible and incompressible porous medium models are used in the literature to describe the mechanical properties of living tissues. These two classes of models can be related using a stiff pressure law. In the incompressible limit, the compressible model generates a free boundary problem of Hele-Shaw type where incompressibility holds in the saturated phase. Here we consider the case with a nutrient. Then, a badly coupled system of equations describes the cell density number and the nutrient concentration. For that reason, the derivation of the free boundary (incompressible) limit was an open problem, in particular a difficulty is to establish the so-called complementarity relation which allows to recover the pressure using an elliptic equation. To establish the limit, we use two new ideas. The first idea, also used recently for related problems, is to extend the usual Aronson-Bénilan estimates in $L^\infty$ to an $L^2$ setting. The second idea is to derive a sharp uniform $L^4$ estimate on the pressure gradient, independently of space dimension.