1. Waste-grass-mediated green synthesis of silver nanoparticles and evaluation of their anticancer, antifungal and antibacterial activity
- Author
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Mehrdad Khatami, Niloofar Zafarnia, Iraj Sharifi, Mohammad Reza Aflatoonian, Marcos Augusto Lima Nobre, Bam Univ Med Sci, Shiraz Univ Med Sci, Kerman Univ Med Sci, and Universidade Estadual Paulista (Unesp)
- Subjects
Antifungal ,medicine.drug_class ,Nanoparticle ,Waste material ,02 engineering and technology ,010402 general chemistry ,01 natural sciences ,inhibitory effect ,Silver nanoparticle ,lcsh:Chemistry ,Average size ,parasitic diseases ,otorhinolaryngologic diseases ,medicine ,Environmental Chemistry ,lcsh:Science ,Inhibitory effect ,Chemistry ,green synthesis ,food and beverages ,General Chemistry ,021001 nanoscience & nanotechnology ,0104 chemical sciences ,antibacterial ,lcsh:QD1-999 ,nanoparticles ,lcsh:Q ,Particle size ,0210 nano-technology ,Antibacterial activity ,antifungal ,Nuclear chemistry - Abstract
Made available in DSpace on 2018-11-26T17:48:43Z (GMT). No. of bitstreams: 0 Previous issue date: 2018-01-01 National Institute for Medical Research Development (NIMAD) Grass waste was used for transform an inexpensive waste into health. Silver nanoparticles (AgNPs) have been synthesized using waste material (dried grass). The average size of silver nanoparticles observed in transmission electron images was estimated to be about 15nm. The anticancer, antifungal and antibacterial effect of AgNPs were studied in vitro. The minimum inhibitory concentration of AgNPs against Pseudomonas aeruginosa and Acinetobacter baumannii was calculated about 3 mu g/ml. The highest level of inhibitory effect of AgNPs against Fusarium solani was close to 90% at a concentration of 20g/ml of AgNPs. An inhibitory effect on the cancer cell growth is reach, by increasing the concentration of AgNPs to 5 mu g/ml; the cancer cells' survival decreases about 30%. Western results showed that the expression of Cyclin D1 protein of MCF-7 cell line decreased after treatment with the effective concentration of AgNPs. [GRAPHICS] . Bam Univ Med Sci, Nanobioelectrochem Res Ctr, Bam, Iran Shiraz Univ Med Sci, Nanomed & Nanobiol Res Ctr, Shiraz, Iran Kerman Univ Med Sci, Leishmaniasis Res Ctr, Kerman, Iran Sao Paulo State Univ, Sch Sci & Technol, Dept Phys, UNESP Presidente Prudente Brazil, Sao Paulo, Brazil Kerman Univ Med Sci, Res Ctr Trop & Infect Dis, Kerman, Iran Sao Paulo State Univ, Sch Sci & Technol, Dept Phys, UNESP Presidente Prudente Brazil, Sao Paulo, Brazil National Institute for Medical Research Development (NIMAD): 963543
- Published
- 2018
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