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In the present paper, we study strength anisotropy of VT6 titanium alloy additively manufactured by laser metal deposition. The Hugoniot elastic limit and spall strength of the alloy are measured depending on the direction of deposition, the ratio of primary and secondary powders, and preliminary heat treatment. The measurements are performed by recording and analyzing full wave profiles under shock compression at the amplitude 10 GPa. The additively manufactured titanium alloy demonstrates strength isotropy, and its strength characteristics are slightly higher than those of conventionally manufactured industrial specimens. The concentration of secondary powder during additive manufacturing also exerts no effect on strength properties of the alloy, both under static and dynamic loads.

The article describes in detail the evidence on validation and classification of existing devices for blood pressure self-control (BPSC). The strengths and limitations of BPSC are discussed, together with modern approaches to research and clinical application of BPSC as independent method or in combination with traditional BP measurement. The current clinical and epidemiologic evidence on BPSC is analysed. Technical and clinical aspects of the method in general and of tonometer use, in particular, are emphasised.

The transition from the identification of individual risk factors to the assessment of an overall or total risk, in other words, to the creation of prognostic models should be now recognized to be one of the most important achievements in the epidemiology of chronic noncommunicable diseases. The paper comparatively analyzes major current prognostic algorithms for assessing the risk of cardiovascular diseases and their events and the advantages and disadvantages of these algorithms. The authors provide evidence that it is necessary to create national risk models, including the most promising new indicators.

The current status of obesity (O) as a global problem justifies the use of the term “obesity epidemic”, since the prevalence of O has increased substantially, in contrast to the decreasing prevalence of other risk factors (RFs).Aim.This analysis assessed the all-cause (AC) and cardiovascular disease (CVD) mortality levels by body mass index (BMI) in a middleaged Russian population.Material and methods.The present analysis included the data from seven studies performed by the State Research Centre for Preventive Medicine in 1975–2001. The total number of participants was 17821: 12887 men and 4934 women, aged 35–74 years. All participants were examined following the same protocol. The following parameters were analysed: socio-demographic and behavioural characteristics, lipid and carbohydrate metabolism disturbances, and clinical parameters. All participants were divided into seven categories by their BMI values: from BMI Conclusion.The observed tendency of elevated CVD risk in people with O suggests that particular attention should be paid to this risk factor. Adverse effects of O have also been demonstrated for people with arterial hypertension and diabetes mellitus. For the latter, its prevalence has substantially increased in Russia over the past years.

Aim. To study the prevalence of arterial hypertension (AH) in the population of Kyrgyz small towns and countryside and to analyse ethnic features of AH.Material and methods. This cross-sectional epidemiologic study was performed as a part of the international study INTEREPID. A random sample of small town and countryside residents included 1774 people. The examination included a questionnaire survey, measurement of blood pressure, height, weight, and waist circumference, and laboratory tests. AH prevalence was age-standardised.Results. In Kyrgyz small town and countryside residents aged 18–65 years, the prevalence of AH was 44% (33,2% in men and 46,7% in women). Among Kyrgyz participants, AH prevalence was significantly lower than in their Russian peers (36,8% vs. 46,2%, respectively). This difference was observed in women, while men did not demonstrate any marked ethnic differences in AH prevalence.Conclusion. The results obtained suggest that AH prevalence in the Kyrgyz Republic is high (with a 40–50% increase over the past 20 years) and is characterised by marked gender and ethnic differences. Further research is required to identify whether race/ethnic group could be a risk factor for AH development.