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3. MOESM12 of Adverse effects of Hif1a mutation and maternal diabetes on the offspring heart

Author

Cerychova, Radka, Bohuslavova, Romana, Frantisek Papousek, Sedmera, David, Abaffy, Pavel, Benes, Vladimir, Frantisek Kolar, and Pavlinkova, Gabriela

Subjects
embryonic structures, cardiovascular system
Abstract

Additional file 12: Figure S3. PECAM-1 expression in the LV. Representative images of staining of PECAM-1 (red) with Hoechst stained cell nuclei (blue) in the LV of 12 week-old offspring (a-d). Scale bar = 50 μm. e-h: Delineated PECAM+ area in the myocardium using Adobe Photoshop. Quantification of PECAM-1 staining determined as a percentage of positive area in the field of view by ImageJ (i). The values are mean ± SEM (n = 4). Statistical significance assessed by two-way ANOVA: genotype effect P = 0.0302, followed by post hoc Tukey’s multiple-comparison test with no significant result.

Published
2018
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5. MOESM11 of Adverse effects of Hif1a mutation and maternal diabetes on the offspring heart

Author

Cerychova, Radka, Bohuslavova, Romana, Frantisek Papousek, Sedmera, David, Abaffy, Pavel, Benes, Vladimir, Frantisek Kolar, and Pavlinkova, Gabriela

Abstract

Additional file 11: Figure S2. Quantification of TUNEL+ apoptotic cells per mm2 of the RV myocardium (a) and septum (b). The values are mean ± SEM (n = 4 individuals/3 sections/group). Two-way ANOVA indicating a significant effect of diabetes (RV: P < 0.0001; septum: P < 0.0001) followed by post hoc Tukey’s multiple-comparison test, **P < 0.01, ***P < 0.001, **** P < 0.0001.

Published
2018
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