1. Human Gingival Fibroblasts Cell Viability of Poly(Lactic Acid) Powder Reinforced PMMA/Hydroxyapatite Biocomposites
- Author
-
H. Hashim, S. N. F. Mohd Noor, Wen Shyang Chow, Z. A. Mohd Ishak, and K. Ng
- Subjects
chemistry.chemical_classification ,Materials science ,Polymers and Plastics ,Biocompatibility ,Flexural modulus ,General Chemical Engineering ,Confocal ,technology, industry, and agriculture ,macromolecular substances ,Polymer ,equipment and supplies ,Poly(methyl methacrylate) ,Analytical Chemistry ,Lactic acid ,chemistry.chemical_compound ,stomatognathic system ,chemistry ,Chemical engineering ,visual_art ,visual_art.visual_art_medium ,Viability assay ,Composite material ,Methyl methacrylate - Abstract
The dental composites based on poly(methyl methacrylate)/hydroxyapatite (PMMA/HA) were prepared through heat-processing polymer powder-liquid method, in the presence of poly(lactic acid) powder (PLA; 5–20 phr). The PLA powder enhanced the flexural modulus and strength of PMMA/HA composites. The Alamar Blue assay results indicated the PMMA/HA/PLA composites were able to sustain human gingival fibroblasts (HGF) cells growth. The images of live/dead cells confocal showed the populations of living cells on the composites surface were confluent and the survival of HGF cells on the PMMA composites surface are assured. These features suggested that the PLA powder reinforced PMMA/HA composites demonstrated excellent biocompatibility.
- Published
- 2014