1. Left Ventricular Diastolic Function in Healthy Adult Individuals: Results of the World Alliance Societies of Echocardiography Normal Values Study
- Author
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Tania Regina Afonso, Hye Rim Yun, Karima Addetia, Ravi R Kasliwal, Aldo D. Prado, Eduardo Filipini, Ricardo E. Ronderos, C Palermo, Tomoko Nakao, Manish Bansal, Takayuki Kawata, Agatha Kwon, Ana Clara Tude Rodrigues, Yu Zhang, Gregory M. Scalia, Sameer Desale, Rodolfo Citro, Maala Sooriyakanthan, Dolapo Fasawe, Michele Bellino, Wendy Tsang, Samantha Hoschke-Edwards, R. Alagesan, Luigi P. Badano, R.V.A. Ananth, Babitha Thampinathan, Mark J. Monaghan, S. Balasubramanian, Masaaki Takeuchi, Davide Di Vece, James N. Kirkpatrick, Mei Zhang, Seung Woo Park, Edwin S. Tucay, Eduardo Bossone, Roberto M. Lang, Naoko Sawada, Yun Zhang, Tiangang Zhu, Anita Sadeghpour, Lixue Yin, Denisa Muraru, Yingbin Wang, Yousuke Nabeshima, Pedro Gutierrez Fajardo, Shuang Li, Tatsuya Miyoshi, Megumi Hirokawa, Masao Daimon, Alexandra Blitz, Kofo O. Ogunyankin, Zhilong Wang, Jiwon Hwang, Amuthan Vivekanandan, Federico M. Asch, Miyoshi, T., Addetia, K., Citro, R., Daimon, M., Desale, S., Fajardo, P. G., Kasliwal, R. R., Kirkpatrick, J. N., Monaghan, M. J., Muraru, D., Ogunyankin, K. O., Park, S. W., Ronderos, R. E., Sadeghpour, A., Scalia, G. M., Takeuchi, M., Tsang, W., Tucay, E. S., Tude Rodrigues, A. C., Vivekanandan, A., Zhang, Y., Blitz, A., Lang, R. M., Asch, F. M., Prado, A. D., Filipini, E., Kwon, A., Hoschke-Edwards, S., Regina Afonso, T., Thampinathan, B., Sooriyakanthan, M., Zhu, T., Wang, Z., Wang, Y., Zhang, M., Yin, L., Li, S., Alagesan, R., Balasubramanian, S., Ananth, R. V. A., Bansal, M., Badano, L. P., Palermo, C., Bossone, E., Di Vece, D., Bellino, M., Nakao, T., Kawata, T., Hirokawa, M., Sawada, N., Nabeshima, Y., Yun, H. R., Hwang, J. -W., Fasawe, D., Miyoshi, T, Addetia, K, Citro, R, Daimon, M, Desale, S, Fajardo, P, Kasliwal, R, Kirkpatrick, J, Monaghan, M, Muraru, D, Ogunyankin, K, Park, S, Ronderos, R, Sadeghpour, A, Scalia, G, Takeuchi, M, Tsang, W, Tucay, E, Tude Rodrigues, A, Vivekanandan, A, Zhang, Y, Blitz, A, Lang, R, Asch, F, Prado, A, Filipini, E, Kwon, A, Hoschke-Edwards, S, Regina Afonso, T, Thampinathan, B, Sooriyakanthan, M, Zhu, T, Wang, Z, Wang, Y, Zhang, M, Yin, L, Li, S, Alagesan, R, Balasubramanian, S, Ananth, R, Bansal, M, Badano, L, Palermo, C, Bossone, E, Di Vece, D, Bellino, M, Nakao, T, Kawata, T, Hirokawa, M, Sawada, N, Nabeshima, Y, Yun, H, Hwang, J, and Fasawe, D
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Adult ,Male ,medicine.medical_specialty ,Diastolic function ,Normal values ,030204 cardiovascular system & hematology ,Ventricular Function, Left ,Normal value ,030218 nuclear medicine & medical imaging ,Ventricular Dysfunction, Left ,03 medical and health sciences ,0302 clinical medicine ,Diastole ,Reference Values ,Left atrial ,Internal medicine ,Female patient ,medicine ,Humans ,Cutoff ,Radiology, Nuclear Medicine and imaging ,Aged ,WASE ,business.industry ,MED/11 - MALATTIE DELL'APPARATO CARDIOVASCOLARE ,Guideline ,Cross-Sectional Studies ,Echocardiography ,International ,Cardiology ,Female ,Asian race ,Core laboratory ,Cardiology and Cardiovascular Medicine ,business - Abstract
Background: The World Alliance Societies of Echocardiography (WASE) study was conducted to describe echocardiographic normal values in adults and to compare races and nationalities using a uniform acquisition and measurement protocol. This report focuses on left ventricular (LV) diastolic function. Methods: WASE is an international, cross-sectional study. Participants were enrolled with equal distribution according to age and gender. Echocardiograms were analyzed in a core laboratory based on the latest American Society of Echocardiography/European Association of Cardiovascular Imaging guidelines. Left ventricular diastolic function was assessed by E, E/A, e' velocities, E/e', left atrial volume index (LAVI), and tricuspid regurgitation velocity. Determination of LV diastolic function was made using the algorithm proposed by the guidelines. Results: A total of 2,008 subjects from 15 countries were enrolled. The majority were of white or Asian race (42.8%, 41.8%, respectively). E and E/e' were higher in female patients, while LAVI was similar in both genders. Consistent increase in E/e' and decrease in E/A, E, and e' were found as age increased. The upper limit of normal for LAVI was higher in WASE compared with the guidelines. The lower limits of normal for e' were smaller in elder groups than those in the guidelines, while the upper limits of normal for E/e' were below the guideline values. These findings suggest that the cutoff value for LAVI should be shifted upward and age-specific cutoff values for e' should be considered. In WASE
- Published
- 2020
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