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1. Dynamics of metabolic characteristics, markers of oxidative stress and vascular wall damage during treatment of obese prediabetic patients

Author

Romanenko La, Mavrycheva Nv, Budnikova Nv, Grinshtein Vb, and Polyatykina T S

Subjects
Vascular wall, medicine.medical_specialty, business.industry, General Medicine, 030204 cardiovascular system & hematology, Carbohydrate metabolism, medicine.disease, medicine.disease_cause, 03 medical and health sciences, 0302 clinical medicine, Endocrinology, Diabetes mellitus, Internal medicine, medicine, Microalbuminuria, 030212 general & internal medicine, business, Oxidative stress
Abstract

We studied lipid and carbohydrate metabolism, markers of oxidative stress (plasma malonic dialdehyde and dienoic conjugates) and vascular wall damage (CRP, microalbuminuria, blood desquamated endotheliocytes) before and after 12 week treatment of obese pre-diabetic patients. The study showed positive dynamics of the above metabolic parameters with normalization of carbohydrate metabolism in 60% of the patients and angioprotective effect ofprescribed therapy. The proposed treatment can be used to prevent diabetes mellitus.

Published
2016

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