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Our goal is to estimate the star formation main sequence (SFMS) and the star formation rate density (SFRD) at z 8 and it is clearly defined by the blue galaxies, with the red galaxies located below them. The SFMS is described as log SFR = 0.83 log M - 8.44. We find a good agreement with previous estimations of the SFMS, especially those based on integral field spectroscopy. The Halpha luminosity function of the AGN-free sample is well described by a Schechter function with log L* = 41.34, log phi* = -2.43, and alpha = -1.25. Our measurements provide a lower characteristic luminosity than several previous studies in the literature. The derived star formation rate density at d < 75 Mpc is log rho_SFR = -2.10 +- 0.11, with red galaxies accounting for 15% of the SFRD. Our value is lower than previous estimations at similar redshift, and provides a local reference for evolutionary studies regarding the star formation history of the Universe., 26 pages. Accepted for publication in Astronomy and Astrophysics

In the present paper we aim to validate a methodology designed to extract the Halpha emission line flux from J-PLUS photometric data. J-PLUS is a multi narrow-band filter survey carried out with the 2 deg2 field of view T80Cam camera, mounted on the JAST/T80 telescope in the OAJ, Teruel, Spain. The information of the twelve J-PLUS bands, including the J0660 narrow-band filter located at rest-frame Halpha, is used over 42 deg2 to extract de-reddened and [NII] decontaminated Halpha emission line fluxes of 46 star-forming regions with previous SDSS and/or CALIFA spectroscopic information. The agreement of the inferred J-PLUS photometric Halpha fluxes and those obtained with spectroscopic data is remarkable, with a median comparison ratio R = 1.05 +- 0.25. This demonstrates that it is possible to retrieve reliable Halpha emission line fluxes from J-PLUS photometric data. With an expected area of thousands of square degrees upon completion, the J-PLUS dataset will allow the study of several star formation science cases in the nearby universe, as the spatially resolved star formation rate of nearby galaxies at z < 0.015, and how it is influenced by the environment, morphology or nuclear activity. As an illustrative example, the close pair of interacting galaxies NGC3994 and NGC3995 is analyzed, finding an enhancement of the star formation rate not only in the center, but also in outer parts of the disk of NGC3994., 13 pages, 8 figures, 3 tables. Submitted to Astronomy and Astrophysics. Comments are welcome

The spatial variations of stellar population properties within a galaxy are intimately related to their formation process. Therefore, spatially resolved studies of galaxies are essential to uncover their formation and assembly. The Javalambre Photometric Local Universe Survey (J-PLUS) is a dedicated multi-filter designed to observed ~8500 deg2 using twelve narrow-, intermediate- and broad-band filters in the optical range. In this study, we test the potential of the multi-filter observation carried out with J-PLUS to investigate the properties of spatially-resolved nearby galaxies. We present detailed 2D maps of stellar population properties (age, metallicity, extinction, and stellar mass surface density) for two early-type galaxies observed in both, J-PLUS and CALIFA surveys: NGC 5473 and NGC 5485. Radial structures are also compared and luminosity- and mass-weighted profiles are derived. We use MUFFIT to process the J-PLUS observations, and two different techniques (STARLIGHT and STECKMAP) to analyze IFU CALIFA data. We demonstrate that this novel technique delivers radial stellar population gradients in good agreement with the IFU technique CALIFA/STECKMAP although comparison of the absolute values reveals the existence of intrinsic systematic differences. Radial stellar population gradients differ when CALIFA/STARLIGHT methodology is used. Age and metallicity radial profiles derived from J-PLUS/MUFFIT are very similar when luminosity- or mass-weighted properties are used, suggesting that the contribution of a younger component is small. Comparison between the three methodologies reveals some discrepancies suggesting that the specific characteristics of each method causes important differences. We conclude that the ages, metallicities and extinction derived for individual galaxies not only depend on the chosen models but also depend on the method used., Comment: Submitted to Astronomy and Astrophysics. 19 pages, 12 figures, 5 tables

Introduction: The improvement in the prognosis of HIV infection, coupled with the increase in international travel and migration, has led to a rising number of HIV infected travelers. The objective of this study was to describe the epidemiological and clinical features of returning travelers, according to their HIV status. Methods: An observational prospective study was conducted including travelers and immigrants who traveled to visit friends and relatives (VFRs) registered in the +REDIVI collaborative network (January-2009; October-2014). +REDIVI is a national network that registers information regarding infections imported by travelers and immigrants at 21 different centers using a standardized protocol. Results: A total of 3464 travellers were identified: 72 were HIV+ (2.1%) and 3.392 HIV-(98%). HIV+ vs. HIV travelers were often older (40.5y vs. 34.2y P = .001), VFRs (79.1% vs. 44.4%; P < .001), and consulted less for pre-travel advice (27% vs. 37%; P = .078). The main destinations for both groups were sub-Saharan Africa and Latin America. The most frequent reasons for consultation after travel were fever, request for a health examination, gastrointestinal complaints, and abnormal laboratory tests (mainly eosinophilia and anemia), which differed between groups. The most frequent diagnoses in HIV+ travelers were malaria (38.8%), newly diagnosed HIV infection (25%), and intestinal parasites (19.4%), while for HIV-travelers the main diagnoses were "healthy" (17.9%), malaria (14%), and intestinal parasites (17.3%). Conclusions: The typical profile of an HIV+ traveler in +REDIVI was that of a VFR traveler who did not seek pre-travel advice and made high-risk trips. This may increase the chance of acquiring travel-related infections which may pose a special risk for HIV-infected travelers. The post-travel visit was a good opportunity for HIV infection screening. (C) 2015 Elsevier Espana, S.L.U. and Sociedad Espanola de Enfermedades Infecciosas y Microbiologia Clinica. All rights reserved.

Introduction: The improvement in the prognosis of HIV infection, coupled with the increase in international travel and migration, has led to a rising number of HIV infected travelers. The objective of this study was to describe the epidemiological and clinical features of returning travelers, according to their HIV status. Methods: An observational prospective study was conducted including travelers and immigrants who traveled to visit friends and relatives (VFRs) registered in the +REDIVI collaborative network (January-2009; October-2014). +REDIVI is a national network that registers information regarding infections imported by travelers and immigrants at 21 different centers using a standardized protocol. Results: A total of 3464 travellers were identified: 72 were HIV+ (2.1%) and 3.392 HIV-(98%). HIV+ vs. HIV travelers were often older (40.5y vs. 34.2y P = .001), VFRs (79.1% vs. 44.4%; P < .001), and consulted less for pre-travel advice (27% vs. 37%; P = .078). The main destinations for both groups were sub-Saharan Africa and Latin America. The most frequent reasons for consultation after travel were fever, request for a health examination, gastrointestinal complaints, and abnormal laboratory tests (mainly eosinophilia and anemia), which differed between groups. The most frequent diagnoses in HIV+ travelers were malaria (38.8%), newly diagnosed HIV infection (25%), and intestinal parasites (19.4%), while for HIV-travelers the main diagnoses were "healthy" (17.9%), malaria (14%), and intestinal parasites (17.3%). Conclusions: The typical profile of an HIV+ traveler in +REDIVI was that of a VFR traveler who did not seek pre-travel advice and made high-risk trips. This may increase the chance of acquiring travel-related infections which may pose a special risk for HIV-infected travelers. The post-travel visit was a good opportunity for HIV infection screening. (C) 2015 Elsevier Espana, S.L.U. and Sociedad Espanola de Enfermedades Infecciosas y Microbiologia Clinica. All rights reserved.

We present the main steps that will be taken to extract H$��$ emission flux from Javalambre Photometric Local Universe Survey (J-PLUS) photometric data. For galaxies with $z\lesssim0.015$, the H$��$+[NII] emission is covered by the J-PLUS narrow-band filter $F660$. We explore three different methods to extract the H$��$ + [NII] flux from J-PLUS photometric data: a combination of a broad-band and a narrow-band filter ($r'$ and $F660$), two broad-band and a narrow-band one ($r'$, $i'$ and $F660$), and a SED-fitting based method using 8 photometric points. To test these methodologies, we simulated J-PLUS data from a sample of 7511 SDSS spectra with measured H$��$ flux. Based on the same sample, we derive two empirical relations to correct the derived H$��$+[NII] flux from dust extinction and [NII] contamination. We find that the only unbiased method is the SED fitting based one. The combination of two filters underestimates the measurements of the H$��$ + [NII] flux by a 28%, while the three filters method by a 9%. We study the error budget of the SED-fitting based method and find that, in addition to the photometric error, our measurements have a systematic uncertainty of a 4.3%. Several sources contribute to this uncertainty: differences between our measurement procedure and the one used to derive the spectroscopic values, the use of simple stellar populations as templates, and the intrinsic errors of the spectra, which were not taken into account. Apart from that, the empirical corrections for dust extinction and [NII] contamination add an extra uncertainty of 14%. Given the J-PLUS photometric system, the best methodology to extract H$��$ + [NII] flux is the SED-fitting based one. Using this method, we are able to recover reliable H$��$ fluxes for thousands of nearby galaxies in a robust and homogeneous way., 11 pages, 14 figures. Minor changes to match the published version

Background/Objectives Obesity has been linked to morbidity and mortality through increased risk for many chronic diseases. Endothelin (EDN) system has been related to endothelial function but it can be involved in lipid metabolism regulation: Receptor type A (EDNRA) activates lipolysis in adipocytes, the two endothelin receptors mediate arsenic-stimulated adipocyte dysfunction, and endothelin system can regulate adiposity by modulating adiponectin activity in different situations and, therefore, influence obesity development. The aim of the present study was to analyze if single nucleotide polymorphisms (SNPs) in the EDN system could be associated with human obesity. Subjects/Methods We analyzed two samples of general-population-based studies from two different regions of Spain: the VALCAR Study, 468 subjects from the area of Valencia, and the Hortega Study, 1502 subjects from the area of Valladolid. Eighteen SNPs throughout five genes were analyzed using SNPlex. Results We found associations for two polymorphisms of the EDNRB gene which codifies for EDN receptor type B. Genotypes AG and AA of the rs5351 were associated with a lower risk for obesity in the VALCAR sample (p=0.048, OR=0.63) and in the Hortega sample (p=0.001, OR=0.62). Moreover, in the rs3759475 polymorphism, genotypes CT and TT were also associated with lower risk for obesity in the Hortega sample (p=0.0037, OR=0.66) and in the VALCAR sample we found the same tendency (p=0.12, OR=0.70). Furthermore, upon studying the pooled population, we found a stronger association with obesity (p=0.0001, OR=0.61 and p=0.0008, OR=0.66 for rs5351 and rs3759475, respectively). Regarding plasma arsenic levels, we have found a positive association for the two SNPs studied with obesity risk in individuals with higher arsenic levels in plasma: rs5351 (p=0.0054, OR=0.51) and rs3759475 (p=0.009, OR=0.53) Conclusions Our results support the hypothesis that polymorphisms of the EDNRB gene may influence the susceptibility to obesity and can interact with plasma arsenic levels.

Summary: The main objective was to evaluate the association between SNPs and haplotypes of the FABP1-4 genes and type 2 diabetes, as well as its interaction with fat intake, in one general Spanish population. The association was replicated in a second population in which HOMA index was also evaluated. Methods: 1217 unrelated individuals were selected from a population-based study [Hortega study: 605 women; mean age 54 y; 7.8% with type 2 diabetes]. The replication population included 805 subjects from Segovia, a neighboring region of Spain (446 females; mean age 52 y; 10.3% with type 2 diabetes). DM2 mellitus was defined in a similar way in both studies. Fifteen SNPs previously associated with metabolic traits or with potential influence in the gene expression within the FABP1- 4 genes were genotyped with SNPlex and tested. Age, sex and BMI were used as covariates in the logistic regression model. Results:One polymorphism (rs2197076) and two haplotypes of the FABP-1 showed a strong association with the risk of DM2 in the original population. This association was further confirmed in the second population as well as in the pooled sample. None of the other analyzed variants in FABP2, FABP3 and FABP4 genes were associated. There was not a formal interaction between rs2197076 and fat intake. A significant association between the rs2197076 and the haplotypes of the FABP1 and HOMA-IR was also present in the replication population. Conclusions: The study supports the role of common variants of the FABP-1 gene in the development of type 2 diabetes in Caucasians.

The aim of this work is to compare the effectiveness of two psychoeducational interventions for dementia caregivers: a cognitive behavioral one (PCC), aimed at the modification of dysfunctional thoughts about caregiving, and another one consisting in problem solving skills training (PSP) for caregivers, with the aim of modifying the behavioral problems of their relative.Seventy five caregivers were asked to participate in an intervention program, of whom 31 finally completed the study. Both group interventions are compared with a control group (CG). The caregiver groups were randomly assigned to each experimental condition. Pre, post intervention, and follow up assessments of the following variables have been made: depression, perceived stress, frequency of behavioral problems, perceived stress associated with the behavioral problems and dysfunctional thoughts about caregiving.Following the intervention, caregivers in the PCC program show significantly less perceived stress than the other two groups. In the same direction, a trend exists to a significant reduction of the stress associated with the behavioral problems. In the follow up assessment, caregivers of the PCC program significantly report less relative's behavioral problems than the other two groups. Caregivers of the PCC program have less dysfunctional thoughts than the other two groups, differences almost reaching significance.Benefits of a psychoeducational intervention vary as a function of the contents it includes. The importance of intervening on the caregiver dysfunctional thoughts for an adequate coping with caregiving is highlighted.

l. Suelos. Química. Diagramas de estabilidad mineral. Interpretación y aplicaciones en el estudio de los procesos de alteración edáficos. Por P. Díaz del Castillo y J. L. Martín de Vidales.-- Relaciones entre bloques medioambientales y balances de materia para contaminantes metálicos. Por F. Romero, C. Elejalde, l. Gracia y J. M. Díaz.-- Elementos cambiables en suelos ácidos bajo pasto: Estudio comparativo de métodos para la extracción y determinación de Ca, Mg y Al. Por A. J. Hernández, R. González y M. Alcubilla.-- Materia orgánica y elementos traza en las intercalaciones pizarrosas de la «Cuarcita del Criadero». Yacimiento de Almadén (Ciudad Real). Por J. B. Alvarez Martín, J. Monseur Lespagnard, J. Guijarro Galiana y F. Sanz.-- l. Suelos- Biología.-- Contribución al estudio de los suelos y sedimentos de montaña de Galicia y su cronología por análisis polínico. III. Cuenca glaciar del Alto Cenza, Sierra de Queixa (Orense) y discusión general de resultados. Por M. J. Aira Rodríguez y F. Guitián Ojea.-- l. Suelos- Génesis, clasificación y cartografía - Contribución de la mineralogía de la fracción arena al estudio de la edafogénesis en una zona semiárida de la provincia de Valladolid. II. Aplicación de análisis factorial en componentes principales. Datos analíticos. Por M. P. García Rodríguez.-- Contribución de la mineralogía de la fracción arena al estudio de la edafogénesis en una zona semiárida de la provincia de Valladolid. III. Aplicación del análisis factorial en componentes principales. Datos mineralógicos. Por M. P. García Rodríguez.-- Contribución de la mineralogía de la fracción arena al estudio de la edafogénesis en una zona semiárida de la provincia de Valladolid. I. Análisis mineralógico: interpretación general. Por M. P. García Rodríguez. l. Suelos – Fertilidad. Relación entre la fertilidad natural y la mineralogía de algunos suelos sobre materiales volcánicos. Por N. García Calderón, A. Pinilla, T. Aleixandre y N. Aguilera.-- Efecto de la fertilización de la viña con estiércol y K en la zona de Méntrida. Por J. A. Díez. II. Biología Vegetal.- Fisiología - La floración abundante en almendro. Por J. Egea Caballero, L. Egea lbáñez y T. Berenguer Hernández.-- Fisiología de la producción de grano y de proteínas en cultivos de trigo blando (Triticum aestivum L.), Trigo duro (T. turgidum L.) y Triticale (XTriticosecale Wittmack). Por G. Rojo y L. F. García del Moral. II. Biología Vegetal-Agro biología. Un nuevo método para el estudio de las relaciones entre vegetación y geomorfología. Por M. Ruiz y A. Pou.-- Respuesta de la planta de lechuga (Lactuca saliva) a diversos tratamientos de lignito. Por C. Fortun, M. L. Salas y C. Ortega.-- Utilización de los lignitos como enmiendas orgánicas. Por M. L. Salas, C. Fortun y C. Ortega.-- III. Trabajos recapitulativos. Etileno y germinación. Por l. M. Sánchez-Calle.-- IV. Comunicaciones cortas. Variación del pH del sustrato y contenido de diversos nutrientes en explantos de especies leñosas cultivadas «in vitro» (nota previa). Por M. Cantos, J. M. Murillo, A. Troncoso y A. Leva Peer reviewed 2019-08.- CopyBook.- Libnova.- Biblioteca ICA

Journal Article; Research Support, Non-U.S. Gov't; SUMMARY The main objective was to evaluate the association between SNPs and haplotypes of the FABP1-4 genes and type 2 diabetes, as well as its interaction with fat intake, in one general Spanish population. The association was replicated in a second population in which HOMA index was also evaluated. METHODS 1217 unrelated individuals were selected from a population-based study [Hortega study: 605 women; mean age 54 y; 7.8% with type 2 diabetes]. The replication population included 805 subjects from Segovia, a neighboring region of Spain (446 females; mean age 52 y; 10.3% with type 2 diabetes). DM2 mellitus was defined in a similar way in both studies. Fifteen SNPs previously associated with metabolic traits or with potential influence in the gene expression within the FABP1-4 genes were genotyped with SNPlex and tested. Age, sex and BMI were used as covariates in the logistic regression model. RESULTS One polymorphism (rs2197076) and two haplotypes of the FABP-1 showed a strong association with the risk of DM2 in the original population. This association was further confirmed in the second population as well as in the pooled sample. None of the other analyzed variants in FABP2, FABP3 and FABP4 genes were associated. There was not a formal interaction between rs2197076 and fat intake. A significant association between the rs2197076 and the haplotypes of the FABP1 and HOMA-IR was also present in the replication population. CONCLUSIONS The study supports the role of common variants of the FABP-1 gene in the development of type 2 diabetes in Caucasians. Yes