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5. Evolution of Sea Spray Aerosol Particle Phase State Across a Phytoplankton Bloom

Author

Allison Kawasaki, Kathryn J. Mayer, Kimberly A. Prather, P. Tumminello, S. Kruse, Reece C. James, Adam Cooper, Karen Lopo Zepeda, Daniel R. Crocker, Isis Guadalupe-Diaz, J. H. Slade, J. S. Sauer, and Christopher T. Lee

Subjects
Atmospheric Science, Space and Planetary Science, Geochemistry and Petrology, Phase state, Environmental science, Particle, Sea spray, Atmospheric sciences, Algal bloom, Aerosol
Published
2021

6. 6-O-(2-[

Author

Marjorie R, Levinstein, Emilya N, Ventriglia, Juan L, Gomez, Reece C, Budinich, János, Marton, Gjermund, Henriksen, Daniel P, Holt, Robert F, Dannals, Martin G, Pomper, Carlos A, Zarate, Jordi, Bonaventura, and Michael, Michaelides

Abstract

6-O-(2-[Here, we report the first characterization of [We also show that [Taken together with prior findings, our results suggest that [

Published
2022

9. Key directions for research and development of superconducting radio frequency cavities

Author

Belomestnykh, S., Posen, S., Bafia, D., Balachandran, S., Bertucci, M., Burrill, A., Cano, A., Checchin, M., Ciovati, G., Cooley, L. D., Semione, G. Dalla Lana, Delayen, J., Eremeev, G., Furuta, F., Gerigk, F., Giaccone, B., Gonnella, D., Grassellino, A., Gurevich, A., Hillert, W., Iavarone, M., Knobloch, J., Kubo, T., Kwok, W. K., Laxdal, R., Lee, P. J., Liepe, M., Martinello, M., Melnychuk, O. S., Nassiri, A., Netepenko, A., Padamsee, H., Pagani, C., Paparella, R., Pudasaini, U., Reece, C. E., Reschke, D., Romanenko, A., Ross, M., Saito, K., Sauls, J., Seidman, D. N., Solyak, N., Sung, Z., Umemori, K., Valente-Feliciano, A. -M., Delsolaro, W. Venturini, Walker, N., Weise, H., Welp, U., Wenskat, M., Wu, G., Xi, X. X., Yakovlev, V., Yamamoto, A., and Zasadzinski, J.

Subjects
Accelerator Physics (physics.acc-ph), Physics::Accelerator Physics, FOS: Physical sciences, Physics - Accelerator Physics, Accelerators and Storage Rings, physics.acc-ph
Abstract

Radio frequency superconductivity is a cornerstone technology for many future HEP particle accelerators and experiments from colliders to proton drivers for neutrino facilities to searches for dark matter. While the performance of superconducting RF (SRF) cavities has improved significantly over the last decades, and the SRF technology has enabled new applications, the proposed HEP facilities and experiments pose new challenges. To address these challenges, the field continues to generate new ideas and there seems to be a vast room for improvements. In this paper we discuss the key research directions that are aligned with and address the future HEP needs., Comment: contribution to Snowmass 2021

Published
2022
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10. Identifying key risks to the performance of privately protected areas (PPAs) through theory of change (ToC)

Author

Francois P. Retief, Reece C. Alberts, Claudine Roos, Dirk C. Cilliers, and Frances Siebert

Subjects
Environmental Engineering, General Medicine, Management, Monitoring, Policy and Law, Waste Management and Disposal
Abstract

Privately protected areas (PPAs) are internationally considered to be important policy implementation instruments to augment and strengthen protected area networks. However, there has been limited reflection on the performance of PPAs over time. This paper aims to identify key risks to the performance of PPAs as policy implementation instruments through the application of Theory of Change (ToC). Identifying and understanding these risks are important to allow for the evaluation and monitoring of PPA performance. The ToC method was applied to a specific PPA policy instrument namely, private nature reserves (PNRs) in the South African context. The research results produced 29 key assumptions translated into 29 key risks. These risk are critically discussed against existing South African and international literature. To test and refine the risks further it is recommended that they be applied to PPA case studies in different contexts.

Published
2022

11. Nb3Sn multicell cavity coating system at JLAB

Author

Eremeev, G., Clemens, W., Macha, K., Reece, C. E., Valente-Feliciano, A. M., Williams, S., Pudasaini, U., and Kelley, M.

Subjects
Accelerator Physics (physics.acc-ph), FOS: Physical sciences, Physics - Accelerator Physics
Abstract

SRF niobium cavities are the building blocks of modern accelerators for scientific applications. Lower surface resistance, higher fields, and high operating temperatures advance the reach of the future accelerators for scientific discovery as well as potentially enabling cost-effective industrial solutions. We describe the design and performance of an Nb$_{3}$Sn coating system that converts the inner surface of niobium cavities to Nb$_{3}$Sn film. Niobium surface, heated by radiation from the niobium retort, is exposed to Sn and SnCl$_{2}$ vapor during the heat cycle, which results in about 2 $��$m Nb$_{3}$Sn film on the niobium surface. Film composition and structure as well as RF properties with 1-cell R\&D cavities and 5-cell practical accelerator cavities are presented.

Published
2020
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12. Patient and surgeon experience during laser in situ keratomileusis using 2 femtosecond laser systems

Author

Cordelia Chan, Reece C. Hall, Jodhbir S. Mehta, Donald T.H. Tan, and Mohamad Rosman

Subjects
Adult, Male, medicine.medical_specialty, genetic structures, Corneal Stroma, medicine.medical_treatment, Keratomileusis, Laser In Situ, Visual Acuity, Keratomileusis, Refraction, Ocular, Surgical Flaps, law.invention, Clinical study, Young Adult, law, Physicians, Surveys and Questionnaires, Ophthalmology, Myopia, otorhinolaryngologic diseases, medicine, Humans, Prospective Studies, business.industry, LASIK, Patient Preference, Validated questionnaire, Light perception, Laser, eye diseases, Sensory Systems, Surgery, Treatment Outcome, Femtosecond, Female, Lasers, Excimer, Subconjunctival hemorrhage, sense organs, business
Abstract

To describe the subjective experience of patients and surgeons during laser in situ keratomileusis (LASIK) using the Intralase 60 kHz or the Visumax 500 kHz femtosecond laser.Singapore National Eye Centre, Singapore.Prospective randomized clinical study.In myopic patients, LASIK was performed with the corneal flap created using the 60 kHz laser in 1 eye and the 500 kHz laser in the contralateral eye. Postoperatively, patients completed a standardized validated questionnaire about their subjective intraoperative experiences (eg, light perception, pain, fear). Surgeons reported their intraoperative experiences and preferences.Loss of light perception occurred in 50.0% of 60 kHz laser cases and 0% of 500 kHz laser cases during docking and in 63.0% and 0% of cases, respectively, during laser flap creation (P.0001). The mean pain score with the 60 kHz laser was significantly higher during docking (P.0001) but not during laser flap cutting (P = .006). Subconjunctival hemorrhage occurred in 67.4% of eyes with the 60 kHz laser and in 2.2% of eyes with the 500 kHz laser (P.0001). The 500 kHz laser was preferred by 78.3% of patients, while 21.7% preferred the 60 kHz laser (P.0001). The surgeons preferred the 60 kHz laser in 50.0% of cases and the 500 kHz laser in 8.7% (P.0001); 41.3% had no preference.Patients preferred surgery with the 500 kHz laser with no loss of light perception, less pain, less fear, and less subconjunctival hemorrhage. Surgeons preferred the 60 kHz laser.

Published
2014

13. Context-dependent role of Grb7 in HER2+ve and triple-negative breast cancer cell lines

Author

Reece C. C. Lim, Jacqueline A. Wilce, and John T. Price

Subjects
Cancer Research, Cell type, Receptor, ErbB-2, Triple Negative Breast Neoplasms, Context (language use), Biology, Breast cancer, medicine, Humans, skin and connective tissue diseases, Triple-negative breast cancer, Cell Proliferation, Cell growth, Estrogens, Cell migration, medicine.disease, Gene Expression Regulation, Neoplastic, Receptors, Estrogen, Oncology, Cell culture, SKBR3, GRB7 Adaptor Protein, Cancer research, Female, Receptors, Progesterone, Signal Transduction
Abstract

Grb7 is an adapter protein, aberrantly co-overexpressed with HER2 and identified as an independent prognostic marker in breast cancer. It has been established that Grb7 exacerbates the cellular growth and migratory behaviour of HER2+ve breast cancer cells. Less is known about Grb7's role in the context of HER2-ve cells. Here we directly compare the effect of stable Grb7 knockdown in oestrogen sensitive (T47D), HER2+ve (SKBR3) and triple-negative (MDA-MB-468 and MDA-MB-231) breast cancer cell lines on anchorage dependent and independent cell growth, wound healing and chemotaxis. All cell lines showed reduced ability to migrate upon Grb7 knockdown, despite their greatly varied endogenous levels of Grb7. Decreased cell proliferation was not observed in any of the cell lines upon Grb7 knockdown; however, decreased ability to form colonies was observed for all but the oestrogen sensitive cell line, depending upon the stringency of the growth conditions. The data reveal that Grb7 plays an important role in breast cancer progression, beyond the context of HER2+ve cell types.

Published
2014

14. Laser in situ keratomileusis flap measurements: Comparison between observers and between spectral-domain and time-domain anterior segment optical coherence tomography

Author

Hla Myint Htoon, Reece C. Hall, Donald T. Tan, Jodhbir S. Mehta, and Farook K. Mohamed

Subjects
Adult, Male, In situ, Materials science, genetic structures, Corneal Stroma, medicine.medical_treatment, Keratomileusis, Laser In Situ, Keratomileusis, Surgical Flaps, Standard deviation, law.invention, Young Adult, Optics, Optical coherence tomography, law, Myopia, medicine, Humans, Body Weights and Measures, Prospective Studies, Time domain, Observer Variation, medicine.diagnostic_test, business.industry, Reproducibility of Results, LASIK, Repeatability, Middle Aged, Laser, eye diseases, Sensory Systems, Ophthalmology, Female, Lasers, Excimer, Surgery, sense organs, business, Nuclear medicine, Tomography, Optical Coherence
Abstract

Purpose To evaluate the between-observer (interobserver) and between-instrument (intraobserver) variability in flap thickness measurements after laser in situ keratomileusis (LASIK) using spectral-domain and time-domain anterior segment optical coherence tomography (AS-OCT). Setting Singapore National Eye Centre. Design Evaluation of diagnostic test or technology. Methods Two independent masked observers measured flap thickness 1 month after LASIK using spectral-domain (RTVue) or time-domain (Visante) AS-OCT. The measurements were taken at central (0.0 mm), −1.5 mm, and +1.5 mm locations. Measurements were repeated to assess between-instrument variability. Results There was no statistically significant difference in mean flap thickness between the 2 observers at −1.5 mm, 0.0 mm, and +1.5 mm on spectral-domain AS-OCT and at −1.5 mm and +1.5 mm on time-domain AS-OCT ( P P =.0008). There was stronger interobserver correlation for spectral-domain AS-OCT at −1.5 mm ( r = 0.82), 0.0 mm ( r = 0.88), and +1.5 mm ( r = 0.88) than for time-domain AS-OCT ( r = 0.73, r = 0.62, and r = 0.79, respectively). There was no statistically significant difference in between-instrument measurements. There was stronger between-instrument correlation with spectral-domain AS-OCT than with time-domain AS-OCT at all locations. The mean standard deviation (measure of instrument repeatability) for spectral-domain AS-OCT was 4.19 μm. Conclusion Spectral-domain AS-OCT had closer agreement in between-observer and between-instrument measurements than time-domain AS-OCT and provided more consistent measurements of post-LASIK flap thickness. Financial Disclosure No author has a financial or proprietary interest in any material or method mentioned.

Published
2011

15. Comparison of fibrin glue with sutures for pterygium excision surgery with conjunctival autografts

Author

Anthony P Wells, Andrew J Logan, and Reece C Hall

Subjects
Adult, Male, medicine.medical_specialty, Time Factors, Pterygium excision, Fibrin Tissue Adhesive, Pterygium, Transplantation, Autologous, law.invention, Young Adult, Postoperative Complications, Suture (anatomy), Randomized controlled trial, Recurrence, law, Humans, Medicine, Vicryl, GLUE, Fibrin glue, Polyglactin 910, Aged, Pain, Postoperative, Sutures, business.industry, Suture Techniques, Middle Aged, medicine.disease, Surgery, Transplantation, Ophthalmology, Treatment Outcome, surgical procedures, operative, Patient Satisfaction, Anesthesia, Female, Tissue Adhesives, business, Conjunctiva, Follow-Up Studies
Abstract

Purpose: To compare pterygium excision conjunctival autograft surgery using Tisseel fibrin glue versus Vicryl sutures. Method: Prospective randomized clinical trial. Fifty patients were randomized into either sutured graft or glued graft groups. Twenty-five received standard conjunctival autograft sutured with Vicryl and 25 received surgery with the autograft placed with Tisseel fibrin glue. Outcome measures include surgical time, patient discomfort, pathology, complications and recurrence rates at 3, 6 and 12 months. Patients were followed up at days 1, 7, 14, 30, 90, 180 and 365. Results: The mean surgical time for the glue group was significantly shorter at 12 min compared with the suture group at 26 min (P

Published
2009

16. Comparison of Two Clinical Bleb Grading Systems

Author

Reece C Hall, Anthony P Wells, N.N. Ashraff, and Gordon Purdie

Subjects
medicine.medical_specialty, Intraclass correlation, Mitomycin, medicine.medical_treatment, Glaucoma, Trabeculectomy, Diagnostic Techniques, Ophthalmological, Blister, Vascularity, Ophthalmology, medicine, Glaucoma surgery, Humans, Prospective Studies, Grading (education), Prospective cohort study, Reproducibility, business.industry, Reproducibility of Results, Repeatability, medicine.disease, eye diseases, Surgery, Fluorouracil, medicine.symptom, business
Abstract

Purpose To evaluate 2 recently described grading systems for clinical grading of filtering surgery blebs: the Moorfields Bleb Grading System (MBGS) and the Indiana Bleb Appearance Grading Scale (IBAGS). Design Observational comparative study. Participants Twenty-four glaucoma filtering blebs in 24 eyes of 17 patients. Methods Three observers in a prospective agreement study compared MBGS with IBAGS during slit-lamp examination. Main Outcome Measures Comparison analyses were performed, including agreement, repeatability, and intraclass correlation coefficient (ICC). Results A wide range of bleb characteristics was represented in the cohort. Acceptable levels of intrasystem agreement were found in both systems: for IBAGS, overall agreement at the 0.5- and 1.0-unit levels were 80.6% and 97.6%, respectively, and for MBGS, these were 78.4% and 97.4% for morphologic and vascularity indices. Repeatability coefficients ranged from 0.5 to 1.4 for MBGS and 0.8 to 1.2 for IBAGS. The ICC values in the MBGS ranged from 0.18 to 0.72 for single measures and 0.39 to 0.88 for average measures. For IBAGS, the single-measure ICC values were between 0.06 and 0.53, and the average-measure ICC values were between 0.16 and 0.77. The MBGS ICC values for bleb size were higher than for IBAGS. Conclusions Both methods are reproducible clinically and had generally high levels of interobserver agreement. Both have minor deficiencies that should be amenable to improvement. The MBGS performed similarly to the IBAGS for reproducibility, had higher ICC values for morphologic features, and captured extra vascularity data with probable clinical implications.

Published
2006

17. Comparative analysis of two femtosecond LASIK platforms using iTRAQ quantitative proteomics

Author

Cordelia Chan, Mohamad Rosman, Lei Zhou, Sharon D’Souza, Louis Tong, Andrea Petznick, Reece C. Hall, Roger W. Beuerman, Jodhbir S. Mehta, and Siew Kwan Koh

Subjects
Adult, Male, Proteomics, medicine.medical_specialty, genetic structures, medicine.medical_treatment, Quantitative proteomics, Tear proteins, Keratomileusis, Laser In Situ, Cornea, Young Adult, Surgical technology, Ophthalmology, Refractive surgery, medicine, Myopia, Humans, Eye Proteins, business.industry, LASIK, Corneal Topography, eye diseases, Protein markers, Surgery, medicine.anatomical_structure, Gene Expression Regulation, Tears, Female, Lasers, Excimer, sense organs, business, Follow-Up Studies
Abstract

New femtosecond laser platforms may reduce ocular surface interference and LASIK-associated dry eye. This study investigated tear protein profiles in subjects who underwent LASIK using two femtosecond lasers to assess differences in protein expression.This was a randomized interventional clinical trial involving 22 patients who underwent femtosecond laser refractive surgery with a contralateral paired eye design. Corneal flaps of 22 subjects were created by either Visumax or Intralase laser. Tear samples were collected preoperatively, and at 1 week and 3 months postoperatively using Schirmer's strips. Tear protein ratios were calculated relative to preoperative protein levels at baseline. The main outcome measures were the levels of a panel of dry eye protein markers analyzed using isobaric tagging for relative and absolute quantitation (iTRAQ) mass spectrometry.A total of 824 unique proteins were quantifiable. Tear protein ratios were differentially regulated between the eyes treated with different lasers. The secretoglobulins Lipophilin A (1.80-fold) and Lipophilin C (1.77) were significantly upregulated (P0.05) at 1 week postoperatively in Visumax but not in Intralase-treated eyes. At 1 week, orosomucoid1 was upregulated (1.78) in Intralase but not Visumax-treated eyes. In the same eyes, lysozyme, cathepsin B, and lipo-oxygenase were downregulated at 0.44-, 0.64-, and 0.64-folds, respectively. Transglutaminase-2 was downregulated in both groups of eyes.Different laser platforms induce distinct biological responses in the cornea and ocular surface, which manifests as different levels of tear proteins. This study has implications for surgical technology and modulation of wound healing responses. (ClinicalTrials.gov number, NCT01252654.).

Published
2014

18. Comparison of efficacy and safety of laser in situ keratomileusis using 2 femtosecond laser platforms in contralateral eyes

Author

Hla Myint Htoon, Reece C. Hall, Jodhbir S. Mehta, Cordelia Chan, Mohamad Rosman, Donald T.H. Tan, Andy Ang, and Jane Koh

Subjects
Adult, Male, medicine.medical_specialty, Distance visual acuity, genetic structures, media_common.quotation_subject, medicine.medical_treatment, Keratomileusis, Laser In Situ, Visual Acuity, Keratomileusis, Refraction, Ocular, Surgical Flaps, law.invention, Contrast Sensitivity, Young Adult, Postoperative Complications, Double-Blind Method, law, medicine, Myopia, Contrast (vision), Humans, Prospective Studies, Intraoperative Complications, media_common, Efficacy index, Excimer laser, business.industry, LASIK, Laser, eye diseases, Sensory Systems, Surgery, Ophthalmology, Treatment Outcome, Femtosecond, Female, Lasers, Excimer, sense organs, business
Abstract

To compare the efficacy, predictability, and refractive outcomes of laser in situ keratomileusis (LASIK) using 2 femtosecond platforms for flap creation.Multisurgeon single center.Clinical trial.Bilateral femtosecond LASIK was performed using the Wavelight Allegretto Eye-Q 400 Hz excimer laser system. The Visumax femtosecond platform (Group 1) was used to create the LASIK flap in 1 eye, while the Intralase femtosecond platform (Group 2) was used to create the LASIK flap in the contralateral eye. The preoperative, 1-month, and 3-month postoperative visual acuities, refraction, and contrast sensitivity in the 2 groups were compared.The study enrolled 45 patients. Three months after femtosecond LASIK, 79.5% of eyes in Group 1 and 82.1% in Group 2 achieved an uncorrected distance visual acuity of 20/20 (P=.808). The mean efficacy index was 0.97 in Group 1 and 0.98 in Group 2 at 3 months (P=.735); 89.7% of eyes in Group 1 and 84.6% of eyes in Group 2 were within ± 0.50 diopter of emmetropia at 3 months (P=.498). No eye in either group lost more than 2 lines of corrected distance visual acuity. The mean safety index at 3 months was 1.11 in Group 1 and 1.10 in Group 2 (P=.570).The results of LASIK with both femtosecond lasers were similar, and both platforms produced efficacious and predictable LASIK outcomes.No author has a financial or proprietary interest in any material or method mentioned.

Published
2012

19. Photodynamic Therapy with Verteporfin for Corneal Neovascularisation

Author

Graham D. Barrett, Chris J Barry, Ian J. Constable, and Reece C Hall

Subjects
Difficult problem, medicine.medical_specialty, genetic structures, business.industry, medicine.medical_treatment, Photodynamic therapy, Corneal neovascularisation, medicine.disease, Verteporfin, eye diseases, Neovascularization, Treatment modality, Ophthalmology, Corneal neovascularization, medicine, sense organs, Lipid keratopathy, medicine.symptom, business, medicine.drug
Abstract

Corneal neovascularization can be a difficult problem to treat. The authors describe a patient with lipid keratopathy secondary to corneal neovascularization treated with photodynamic therapy. Six months following treatment the neovascularization has not returned and the lipid keratopathy has not increased in size. No significant side effects from the treatment occurred. Photodynamic therapy with Verteporfin was a useful treatment modality in this case of corneal neovascularization with associated lipid keratopathy.

Published
2009

20. Abstract 729: Acquired resistance to Hsp90-inhibitors and cancer progression

Author

Reece C. C. Lim, Ryan C. Chai, Michelle M. Kouspou, Benjamin J. Lang, Jessica L. Vieusseux, John T. Price, and Chau H. Nguyen

Subjects
Cancer Research, Cancer, Bone metastasis, Biology, Geldanamycin, medicine.disease, Radicicol, Metastasis, chemistry.chemical_compound, medicine.anatomical_structure, Oncology, chemistry, Osteoclast, Heat shock protein, Immunology, Cancer cell, Cancer research, medicine
Abstract

Heat shock protein 90 (HSP90) is a molecular chaperone required for the stability and function of many proteins. The chaperoning of mutated and over-expressed oncoproteins by HSP90 enhances survival, growth and invasive potential of cancer cells. Many HSP90 inhibitors, including the benzoquinone ansamycin 17-allylamino-17-demethoxygeldanamycin (17-AAG), are currently in clinical evaluation. However the mechanisms and implications of acquired resistance to this class of drug remain largely unexplored. We have generated isogenic human breast cancer cell lines that are resistant to 17-AAG by continued culturing in the compound. High level of resistance was maintained in the 17-AAG resistant cells after cessation of treatment. Cross resistance to other benzoquinone ansamycins such as geldanamycin and 17-DMAG was observed, as well as to compounds structurally unrelated to the benzoquinones such as radicicol, VER50589 and CCT018159. Gene expression profiling and western blot analyses revealed that bone marrow stromal cell antigen 2 (BST2), previously linked to increased bone metastasis, is elevated significantly in the resistant cells. An inverse correlation between the expression of the enzyme NAD(P)H/quinone oxidoreductase 1 (NQO1) and resistance to 17-AAG was also observed. The resistant cells demonstrated significant increase in chemotactic migration and accelerated wound closure. This was coupled by a decrease in growth both in anchorage-dependent and -independent conditions. In vivo study using xenograft mouse model showed decreased mammary tumour formation by the resistant cells. Decreased metastasis of the resistant cells to the lungs was observed following intracardiac inoculation. However, x-ray analysis revealed that nude mice inoculated with resistant cells had enhanced hindlimb bone lesions compared to the parental group. In addition, 17-AAG was also shown to increase the formation of bone resorbing osteoclasts in vitro. Pharmacological inhibition of the transcription factor HSF1 using quercetin and KNK437 suppressed 17-AAG-induced stress response and 17-AAG-enhanced osteoclast formation. These results indicate that resistance to Hsp90 inhibition is accompanied by changes in cancer cell biology that leads to decreased primary tumour formation and lower metastatic tumour burden in vivo. However, severity of bone lesion generated by the resistant cells is greater. 17-AAG also enhances osteoclast formation through a mechanism dependent on HSF1-mediated stress response. Findings from this study furthers our understanding of Hsp90 inhibition on cancer progression and increases our understanding of the potential or lack of, clinical efficacy of Hsp90-directed therapies. Citation Format: {Authors}. {Abstract title} [abstract]. In: Proceedings of the 102nd Annual Meeting of the American Association for Cancer Research; 2011 Apr 2-6; Orlando, FL. Philadelphia (PA): AACR; Cancer Res 2011;71(8 Suppl):Abstract nr 729. doi:10.1158/1538-7445.AM2011-729

Published
2011

21. Central retinal vein occlusion associated with liquorice ingestion

Author

Reece C Hall and Richard Clemett

Subjects
Ophthalmology, medicine.medical_specialty, Blood pressure, Central retinal vein occlusion, biology, business.industry, Medicine, Glycyrrhiza, Ingestion, business, medicine.disease, biology.organism_classification
Published
2004

23. Static pre-load effect on knee extensor isokinetic concentric and eccentric performance

Author

Matthew C. Morrissey, Reece C. Jensen, Carlton Laursen, and Bryan Warren

Subjects
Orthodontics, medicine.medical_specialty, Biomechanics, Repeated measures design, Physical Therapy, Sports Therapy and Rehabilitation, Isometric exercise, Concentric, Preload, Physical therapy, medicine, Eccentric, Torque, Orthopedics and Sports Medicine, medicine.symptom, Mathematics, Muscle contraction
Abstract

The effect of two static pre-load levels on isokinetic concentric (CON) and eccentric (ECC) performance of the knee extensors at 90°-s−1 was evaluated in 35 healthy subjects. The low pre-load level was 50 N, and the high level was 75% of a maximal voluntary isometric contraction, performed at the start angles of 100 degrees (CON) and 30 degrees (ECC) of knee flexion. A two-way ANOVA with two repeated measures (load and angle) and a Newman-Keuls post hoc analysis were performed to compare the interaction of pre-load and angle at every 5 degrees in the ROM. The differences in average torque, peak torque, and peak torque angle between the pre-load levels were also analyzed with repeated-measures Mests. The high pre-load condition had a significant increase in torque at 99, 95, 90, and 85 degrees concentrically and 31, 35, 40, 45, and 50 degrees eccentrically. In comparing the two pre-load conditions over the whole torque curve, there was a significant difference in average torque values of both CON and ECC, no significant difference in peak torque in either contraction, and a significant shift in peak torque angle with CON contractions only.

Published
1991

27. Detector concepts

Author

Aarons, G., Abe, T., Abernathy, J., Ablikim, M., Abramowicz, H., Adey, D., Adloff, C., Adolphsen, C., Afanaciev, K., Agapov, I., Ahn, J. -K, Aihara, H., Akemoto, M., Del Carmenalabau, M., Albert, J., Albrecht, H., Albrecht, M., Alesini, D., Alexander, G., Alexander, J., Allison, W., Amann, J., Amirikas, R., An, Q., Anami, S., Ananthanarayan, B., Anderson, T., Andricek, L., Anduze, M., Anerella, M., Anfimov, N., Angal-Kalinin, D., Antipov, S., Antoine, C., Aoki, M., Aoza, A., Aplin, S., Appleby, R., Arai, Y., Araki, S., Arkan, T., Arnold, N., Arnold, R., Arnowitt, R., Artru, X., Arya, K., Aryshev, A., Asakawa, E., Asiri, F., Asner, D., Atac, M., Atoian, G., Attié, D., Augustin, J. -E, Augustine, D. B., Ayres, B., Aziz, T., Baars, D., Badaud, F., Baddams, N., Bagger, J., Bai, S., Bailey, D., Bailey, I. R., Baker, D., Balalykin, N. I., Balbuena, J. P., Baldy, J. -L, Ball, M., Ballestrero, A., Ballin, J., Baltay, C., Bambade, P., Ban, S., Band, H., Bane, K., Banerjee, B., Barbanotti, S., Barbareschi, D., Barbaro-Galtieri, A., Barber, D. P., Barbi, M., Bardin, D. Y., Barish, B., Barklow, T. L., Barlow, R., Barnes, V. E., Barone, M., Bartels, C., Bartsch, V., Basu, R., Battaglia, M., Batygin, Y., Baudot, J., Baur, U., Baynham, D. E., Beard, C., Bebek, C., Bechtle, P., Becker, U. J., Bedeschi, F., Bedjidian, M., Behera, P., Behnke, T., Bellantoni, L., Bellerive, A., Bellomo, P., Bentson, L. D., Benyamna, M., Bergauer, T., Berger, E., Bergholz, M., Beri, S., Berndt, M., Bernreuther, W., Bertolini, A., Besancon, M., Besson, A., Beteille, A., Bettoni, S., Beyer, M., Bhandari, R. K., Bharadwaj, V., Bhatnagar, V., Bhattacharya, S., Bhattacharyya, G., Bhattacherjee, B., Bhuyan, R., Bi, X. -J, Biagini, M., Bialowons, W., Biebel, O., Bieler, T., Bierwagen, J., Birch, A., Bisset, M., Biswal, S. S., Blackmore, V., Blair, G., Blanchard, G., Blazey, G., Blue, A., Blümlein, J., Boffo, C., Bohn, C., Boiko, V. I., Boisvert, V., Bondarchuk, E. N., Boni, R., Bonvicini, G., Boogert, S., Boonekamp, M., Boorman, G., Borras, K., Bortoletto, D., Bosco, A., Bosio, C., Bosland, P., Bosotti, A., Boudry, V., Boumediene, D. -E, Bouquet, B., Bourov, S., Bowden, G., Bower, G., Boyarski, A., Bozovic-Jelisavcic, I., Bozzi, C., Brachmann, A., Bradshaw, T. W., Brandt, A., Brasser, H. P., Brau, B., Brau, J. E., Breidenbach, M., Bricker, S., Brient, J. -C, Brock, I., Brodsky, S., Brooksby, C., Broome, T. A., Brown, D., Brownell, J. H., Bruchon, M., Brueck, H., Brummitt, A. J., Brun, N., Buchholz, P., Budagov, Y. A., Bulgheroni, A., Bulyak, E., Bungau, A., Bürger, J., Burke, D., Burkhart, C., Burrows, P., Burt, G., Burton, D., Büsser, K., Butler, J., Butterworth, J., Buzulutskov, A., Cabruja, E., Caccia, M., Cai, Y., Calcaterra, A., Caliier, S., Camporesi, T., Cao, J. -J, Cao, J. 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29. German Professoriate under Nazism: A Failure of Totalitarian Aspirations

Author

Reece C. Kelly

Subjects
History, Economic growth, media_common.quotation_subject, Opposition (politics), Nazism, Dictatorship, language.human_language, Education, German, Politics, Scholarship, Law, Political science, language, Nazi Germany, Ideology, media_common
Abstract

THE YEAR 1984 brought much reflection in the popular media on just how far we have become clasped in the totalitarian grip of "big brother." That question quite aside, Orwell's dreaded date should also be a time to examine to what degree the two large dictatorships of his time-the Soviet Union and Nazi Germany-were really in the "total" control of an Orwellian "Party." Though Orwell as a journalist had little to say about the schools and much to say about the press and television serving the totalitarian party, few of his readers, then or now, would fail to reflect on what role schooling from kindergarten to university would play in such a society as Orwell feared. We should share his fear, yet a closer examination of Nazi Germany, particularly its universities, may give some reason for hope too. For it is questionable that the German universities and the ministry of education which administered them ever came to be Orwell's "Ministry of Truth," faithfully and effectively serving the totalitarian party in creating the totalitarian society. Such an examination needs to question or add to the understandings we have had regarding the German universities and particularly the professors, and the degree of influence the Nazi party had over them. These understandings until recently have lacked perspective. Most research focused on the ideological and institutional susceptibilities of German professors and students to the Nazi take-over. Scholarship has analyzed primarily the early months of the regime and has contributed little to our knowledge of the universities during the decade after 1933, except for the students, regarding which several good studies for the whole period exist.' Where the professors have been the concern, writers primarily have sought to explain how the Nazis, with hardly a ripple of opposition, were able to purge from the universities supposed "racial" and political enemies of Nazism-at least 20 percent of Germany's university teachers.2 Indeed, actually only a few professors voiced opposition, while many others in the first months of the regime rushed to associate themselves with the so-called national revolution

Published
1985

30. Das Dritte Reich

Author

Reece C. Kelly and Klaus Hildebrand

Subjects
Cultural Studies, Arts and Humanities (miscellaneous)
Published
1981

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