Search

Background and rationale: Heart failure (HF), which is an emerging public health issue, adversely affects the strained health system in India. The potential adverse impact of HF on the economic well-being of affected individuals and their families is narrated in various anecdotal reports. Further, HF is known to push the affected individuals and their dependents into poverty. However, there is limited research quantifying how HF impacts the economic well-being of households from the low and middle-income countries. Methods: We describe the methods of a detailed economic impact assessment of HF at the household level in India. The economic impact study in HF is initiated across 20 centres in India. The selected centres represent different regions in India stratified based on the prevailing stage of epidemiological transition levels (ETLs). We will collect data from 1800 patients with acute decompensated HF and within 6-15 months of follow-up from the time of initial admission. The data that we intend to collect will consist of a) household healthcare expenditure including out-of-pocket expenditure, b) financing mechanisms used by households and (c) the impoverishing effects of health expenditures including distress financing and catastrophic health expenditure. Trained staff at each centre will collect relevant data by using a validated and structured interview schedule. The study will have 80% power, after accounting for five percent non-response rate, to test eight percent difference in primary outcome (proportion of families under distress financing) between different ETLs. Impact: The results from the study will help policy makers in understanding the micro-economic impact of HF in India and aid in allocation of appropriate resources for prevention and control of HF.

Background and rationale: Heart failure (HF), which is an emerging public health issue, adversely affects the strained health system in India. The potential adverse impact of HF on the economic well-being of affected individuals and their families is narrated in various anecdotal reports. Further, HF is known to push the affected individuals and their dependents into poverty. However, there is limited research quantifying how HF impacts the economic well-being of households from the low and middle-income countries. Methods: We describe the methods of a detailed economic impact assessment of HF at the household level in India. The economic impact study in HF is initiated across 20 centres in India. The selected centres represent different regions in India stratified based on the prevailing stage of epidemiological transition levels (ETLs). We will collect data from 1800 patients with acute decompensated HF and within 6-15 months of follow-up from the time of initial admission. The data that we intend to collect will consist of a) household healthcare expenditure including out-of-pocket expenditure, b) financing mechanisms used by households and (c) the impoverishing effects of health expenditures including distress financing and catastrophic health expenditure. Trained staff at each centre will collect relevant data by using a validated and structured interview schedule. The study will have 80% power, after accounting for five percent non-response rate, to test eight percent difference in primary outcome (proportion of families under distress financing) between different ETLs. Impact: The results from the study will help policy makers in understanding the micro-economic impact of HF in India and aid in allocation of appropriate resources for prevention and control of HF.

Background and rationale: Heart failure (HF), which is an emerging public health issue, adversely affects the strained health system in India. The potential adverse impact of HF on the economic well-being of affected individuals and their families is narrated in various anecdotal reports. Further, HF is known to push the affected individuals and their dependents into poverty. However, there is limited research quantifying how HF impacts the economic well-being of households from the low and middle-income countries. Methods: We describe the methods of a detailed economic impact assessment of HF at the household level in India. The economic impact study in HF is initiated across 20 centres in India. The selected centres represent different regions in India stratified based on the prevailing stage of epidemiological transition levels (ETLs). We will collect data from 1800 patients with acute decompensated HF and within 6-15 months of follow-up from the time of initial admission. The data that we intend to collect will consist of a) household healthcare expenditure including out-of-pocket expenditure, b) financing mechanisms used by households and (c) the impoverishing effects of health expenditures including distress financing and catastrophic health expenditure. Trained staff at each centre will collect relevant data by using a validated and structured interview schedule. The study will have 80% power, after accounting for five percent non-response rate, to test eight percent difference in primary outcome (proportion of families under distress financing) between different ETLs. Impact: The results from the study will help policy makers in understanding the micro-economic impact of HF in India and aid in allocation of appropriate resources for prevention and control of HF.

Heart failure (HF), which is an emerging public health issue, adversely affects the already strained health system in India. Globally, HF unfavorably impacts the economic well-being of the affected individuals and their families, Further, HF is known to push the affected individuals and their dependents into poverty. However, there is limited research quantifying how HF impacts the economic well-being of households from low and middle-income countries. We describe the methods of a detailed economic impact assessment of HF in India. The economic impact study in HF is initiated across 20 centres in India. The selected centres represent different regions in India stratified based on the prevailing stage of epidemiological transition. We aim to collect data from 1800 patients who were admitted with acute decompensated HF and within 6-15 months of follow-up. The data that we intend to collect will consist of a) household healthcare expenditure including out-of-pocket expenditure, b) financing mechanisms used by households and (c) the impoverishing effects of health expenditures including distress financing and catastrophic health expenditure. The results from the study will help policy makers in understanding the micro-economic impact of HF in India and aid in allocation of appropriate resources for prevention and control of HF.

Background and rationale: Heart failure (HF), which is an emerging public health issue, adversely affects the strained health system in India. The potential adverse impact of HF on the economic well-being of affected individuals and their families is narrated in various anecdotal reports. Further, HF is known to push the affected individuals and their dependents into poverty. However, there is limited research quantifying how HF impacts the economic well-being of households from the low and middle-income countries. Methods: We describe the methods of a detailed economic impact assessment of HF at the household level in India. The economic impact study in HF is initiated across 20 centres in India. The selected centres represent different regions in India stratified based on the prevailing stage of epidemiological transition levels (ETLs). We will collect data from 1800 patients with acute decompensated HF and within 6-15 months of follow-up from the time of initial admission. The data that we intend to collect will consist of a) household healthcare expenditure including out-of-pocket expenditure, b) financing mechanisms used by households and (c) the impoverishing effects of health expenditures including distress financing and catastrophic health expenditure. Trained staff at each centre will collect relevant data by using a validated and structured interview schedule. The study will have 80% power, after accounting for five percent non-response rate, to test eight percent difference in primary outcome (proportion of families under distress financing) between different ETLs. Impact: The results from the study will help policy makers in understanding the micro-economic impact of HF in India and aid in allocation of appropriate resources for prevention and control of HF.

Background and rationale: Heart failure (HF), which is an emerging public health issue, adversely affects the strained health system in India. The potential adverse impact of HF on the economic well-being of affected individuals and their families is narrated in various anecdotal reports. Further, HF is known to push the affected individuals and their dependents into poverty. However, there is limited research quantifying how HF impacts the economic well-being of households from the low and middle-income countries. Methods: We describe the methods of a detailed economic impact assessment of HF at the household level in India. The economic impact study in HF is initiated across 20 centres in India. The selected centres represent different regions in India stratified based on the prevailing stage of epidemiological transition levels (ETLs). We will collect data from 1800 patients with acute decompensated HF and within 6-15 months of follow-up from the time of initial admission. The data that we intend to collect will consist of a) household healthcare expenditure including out-of-pocket expenditure, b) financing mechanisms used by households and (c) the impoverishing effects of health expenditures including distress financing and catastrophic health expenditure. Trained staff at each centre will collect relevant data by using a validated and structured interview schedule. The study will have 80% power, after accounting for five percent non-response rate, to test eight percent difference in primary outcome (proportion of families under distress financing) between different ETLs. Impact: The results from the study will help policy makers in understanding the micro-economic impact of HF in India and aid in allocation of appropriate resources for prevention and control of HF.

Background and rationale: Heart failure (HF), which is an emerging public health issue, adversely affects the strained health system in India. The potential adverse impact of HF on the economic well-being of affected individuals and their families is narrated in various anecdotal reports. Further, HF is known to push the affected individuals and their dependents into poverty. However, there is limited research quantifying how HF impacts the economic well-being of households from the low and middle-income countries. Methods: We describe the methods of a detailed economic impact assessment of HF at the household level in India. The economic impact study in HF is initiated across 20 centres in India. The selected centres represent different regions in India stratified based on the prevailing stage of epidemiological transition levels (ETLs). We will collect data from 1800 patients with acute decompensated HF and within 6-15 months of follow-up from the time of initial admission. The data that we intend to collect will consist of a) household healthcare expenditure including out-of-pocket expenditure, b) financing mechanisms used by households and (c) the impoverishing effects of health expenditures including distress financing and catastrophic health expenditure. Trained staff at each centre will collect relevant data by using a validated and structured interview schedule. The study will have 80% power, after accounting for five percent non-response rate, to test eight percent difference in primary outcome (proportion of families under distress financing) between different ETLs. Impact: The results from the study will help policy makers in understanding the micro-economic impact of HF in India and aid in allocation of appropriate resources for prevention and control of HF.

Figure S1: IRM acquisition curves reveal the presence of soft magnetic mineral saturated between 100 and 300 mT. A few samples, reveal a dominant high coercivity anti-ferromagnetic signal; whereas the remaining samples' IRM curves indicate the occurrence of a low coercivity mineral, perhaps magnetite and/or titano-magnetite.

A new simple and sensitive method for the extraction and spectrophotometric determination of selenium(IV) is described. Selenium(IV) is reacted with J acid (6-ANSA) to form a butanol extractable complex with maximum absorbance of 520 nm. Beer's law is obeyed in the range of 0.03-0.3 mg/l. of selenium. Molar absorptivity and Sandell's sensitivity are found to be 18.5 +/- (0.1) x 10(3) l. mol(-1). cm(-1) and 0.004 microg/cm(2), respectively. The analytical parameters were optimized and the method applied for the determination of selenium in polluted water, soil, dust, hair and plant materials. The method is compared with other reported methods and found to be superior to many of the reported methods.