14 results on '"R. J. Ramamurthi"'
Search Results
2. Laparoscopic versus ultrasound-guided visualization of transversus abdominis plane blocks
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R. J. Ramamurthi, Michelle Gibson, John R Austin, Ban C. H. Tsui, Stephanie D. Chao, Jordan S. Taylor, and Modupeola Diyaolu
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Pacu ,Plane (Unicode) ,law.invention ,03 medical and health sciences ,0302 clinical medicine ,Randomized controlled trial ,Block (programming) ,law ,030225 pediatrics ,Humans ,Medicine ,Prospective Studies ,Transversus abdominis ,Child ,Ultrasonography, Interventional ,Abdominal Muscles ,Pain, Postoperative ,biology ,business.industry ,Nerve Block ,General Medicine ,biology.organism_classification ,Ultrasound guided ,Analgesics, Opioid ,Pediatric patient ,030220 oncology & carcinogenesis ,Anesthesia ,Pediatrics, Perinatology and Child Health ,Laparoscopy ,Surgery ,business ,NARCOTIC USE - Abstract
Ultrasound-guided (US) transversus abdominis plane (TAP) block is commonly utilized as part of a multi-modal approach for postoperative pain management. This study seeks to determine whether laparoscopic-guided TAP blocks are as effective as US-guided TAP blocks among pediatric patients.In this prospective, randomized controlled trial, pediatric patients undergoing laparoscopic procedures were randomly assigned to one of two treatment arms: US-guided TAP block (US-arm) or laparoscopic-guided TAP block (LAP-arm). Primary outcome was PACU pain scores. Secondary outcomes included PACU opioid consumption, block completion time and block accuracy.Twenty-five patients were enrolled in each arm. In the LAP-arm, 59% of blocks were in the transversus abdominis plane compared to 74% of TAP blocks in the US-arm (p = 0.18). Blocks were completed faster in the LAP-arm (2.1 ± 1.9 vs. 7.9 ± 3.4 min, p0.001). The average highest PACU pain score was 3.4 ± 3.1 for the LAP-arm and 4.3 ± 3.8 for the US-arm (p = 0.37). Overall PACU pain scores and opioid consumption were similar between the groups (1.2 ± 1.3 vs. 1.6 ± 1.6, p = 0.24; 2.2 ± 5.8 vs. 0.9 ± 1.4MME, p = 0.26).Laparoscopic TAP blocks have equivalent efficacy in post-operative pain scores, narcotic use, and tissue plane accuracy as compared to US-guided TAP blocks. They are also completed faster and may result in less operating room and general anesthetic time for the pediatric patient.
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- 2021
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3. Variation in pediatric local anesthetic dosing for peripheral nerve blocks: an analysis from the Pediatric Regional Anesthesia Network (PRAN)
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Adrian T. Bosenberg, Sean H. Flack, Matthew Hoyt, Michael D. Herrick, R. J. Ramamurthi, David Polaner, Andreas H. Taenzer, Benjamin J. Walker, and Andrew D Franklin
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Bupivacaine ,Local culture ,Ropivacaine ,Local anesthetic ,medicine.drug_class ,business.industry ,General Medicine ,03 medical and health sciences ,0302 clinical medicine ,Anesthesiology and Pain Medicine ,030202 anesthesiology ,Regional anesthesia ,Peripheral nerve ,Anesthesia ,Cohort ,medicine ,030212 general & internal medicine ,Dosing ,business ,medicine.drug - Abstract
BackgroundVariation of local anesthetic dosing has been reported for adult peripheral nerve blocks (PNBs) and infant caudal blocks. As higher doses of local anesthetics (LA) are potentially associated with increased risk of complications (eg, local anesthetic systemic toxicity), it is important to understand the source of LA dose variation. Using the Pediatric Regional Anesthesia Network (PRAN) database, we aimed to determine if variation in dosing exists in pediatric single-injection PNBs, and what factors influence that variation.The primary aim of this study was to determine the factors associated with dosing for the 10 most commonly performed PNBs, with the secondary aim of exploring possible factors for variation such as number of blocks performed versus geographic location.MethodsThe PRAN database was used to determine the 10 most common pediatric PNBs, excluding neuraxial regional anesthetics. The 10 most common pediatric PNBs in the PRAN database were analyzed for variation of LA dose and causes for variation.ResultsIn a cohort of 34 514 children receiving PNBs, the mean age was 10.38 (+/-5.23) years, average weight was 44.88 (+/-26.66) kg and 61.8% were men. The mean bupivacaine equivalent (BE) dose was 0.86 (+/-0.5) mg kg−1 and ropivacaine was used in 65.4% of blocks. Dose decreases with age (estimate −0.016 (−0.017, –0.015; pConclusionsConsiderable variation in dosing exists in all age groups and in all block types. The most impactful driver of local anesthetic dose is the institution where the block was performed, indicating the dosing of a potentially lethal drug is more based on local culture than on evidence.
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- 2020
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4. The Effect of Novel Decision Support Tools on Technical and Non-Technical Performance of Teams in Managing Emergencies
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Scott C, Watkins, Getulio R, de Oliveira Filho, Cory M, Furse, Matthew K, Muffly, R J, Ramamurthi, Amanda T, Redding, Birgit, Maass, and Matthew D, McEvoy
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Patient Care Team ,Communication ,Humans ,Clinical Competence ,Emergencies - Abstract
Cognitive aids have been shown to facilitate adherence to evidence-based guidelines and improve technical performance of teams when managing simulated critical events. Few studies have explored the effect of cognitive aids on non-technical skills, such as teamwork and communication. The current study sought to explore the effects of different decision support tools (DST), a type of cognitive aid, on the technical and non-technical performance of teams. The current study represents a randomized, blinded, control trial of the effects of three versions of an electronic DST on team performance during multiple simulations of perioperative emergencies. The DSTs included a version with only technical information, a version with only non-technical information and a version with both technical and non-technical information. The technical performance of teams was improved when they used the technical DST and the combined technical and non-technical DST when compared to memory alone. The technical performance of teams was significantly worse when using the non-technical DST. All three versions of the DST had a negligible effect on the non-technical performance of teams. The technical performance of teams in the current study was affected by different versions of a DST, yet there was no effect on the teams' non-technical performance. The use of a DST, including those that focused on non-technical information, did not impact the non-technical performance of the teams.
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- 2021
5. Expert Consensus Statement on the Perioperative Management of Adult Patients Undergoing Head and Neck Surgery and Free Tissue Reconstruction From the Society for Head and Neck Anesthesia
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David W. Healy, Benjamin H. Cloyd, Adam I. Levine, R. J. Ramamurthi, Matthew E. Spector, Samuel A. Schechtman, Davide Cattano, Arpan Mehta, Michael F. Aziz, Laura F. Cavallone, Michael Brenner, Joshua H. Atkins, Basem Abdelmalak, Tracey Straker, Amit Saxena, and Edward J. Damrose
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Blood management ,Quality management ,Consensus ,medicine.medical_treatment ,MEDLINE ,Perioperative Care ,03 medical and health sciences ,0302 clinical medicine ,030202 anesthesiology ,medicine ,Humans ,Anesthesia ,Head and neck ,Expert Testimony ,Societies, Medical ,Statement (computer science) ,Adult patients ,business.industry ,Perioperative ,Plastic Surgery Procedures ,Anesthesiologists ,Anesthesiology and Pain Medicine ,Airway management ,business ,Head ,030217 neurology & neurosurgery ,Neck - Abstract
The perioperative care of adult patients undergoing free tissue transfer during head and neck surgical (microvascular) reconstruction is inconsistent across practitioners and institutions. The executive board of the Society for Head and Neck Anesthesia (SHANA) nominated specialized anesthesiologists and head and neck surgeons to an expert group, to develop expert consensus statements. The group conducted an extensive review of the literature to identify evidence and gaps and to prioritize quality improvement opportunities. This report of expert consensus statements aims to improve and standardize perioperative care in this setting. The Modified Delphi method was used to evaluate the degree of agreement with draft consensus statements. Additional discussion and collaboration was performed via video conference and electronic communication to refine expert opinions and to achieve consensus on key statements. Thirty-one statements were initially formulated, 14 statements met criteria for consensus, 9 were near consensus, and 8 did not reach criteria for consensus. The expert statements reaching consensus described considerations for preoperative assessment and optimization, airway management, perioperative monitoring, fluid management, blood management, tracheal extubation, and postoperative care. This group also examined the role for vasopressors, communication, and other quality improvement efforts. This report provides the priorities and perspectives of a group of clinical experts to help guide perioperative care and provides actionable guidance for and opportunities for improvement in the care of patients undergoing free tissue transfer for head and neck reconstruction. The lack of consensus for some areas likely reflects differing clinical experiences and a limited available evidence base.
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- 2021
6. Tools for Assessing the Performance of Pediatric Perioperative Teams During Simulated Crises: A Psychometric Analysis of Clinician Raters' Scores
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Cory M. Furse, Scott C Watkins, Birgit Maass, Amanda T. Redding, R. J. Ramamurthi, Matthew K Muffly, Getúlio Rodrigues de Oliveira Filho, and Matthew D. McEvoy
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medicine.medical_specialty ,Psychometrics ,Epidemiology ,education ,MEDLINE ,Medicine (miscellaneous) ,Education ,03 medical and health sciences ,0302 clinical medicine ,030202 anesthesiology ,Multidisciplinary approach ,medicine ,Humans ,Medical physics ,030212 general & internal medicine ,Child ,Reliability (statistics) ,Patient Care Team ,Reproducibility of Results ,Perioperative ,Checklist ,Inter-rater reliability ,Technical performance ,Modeling and Simulation ,Clinical Competence ,Emergencies ,Psychology - Abstract
Introduction The pediatric perioperative setting is a dynamic clinical environment where multidisciplinary interprofessional teams interact to deliver complex care to patients. This environment requires clinical teams to possess high levels of complex technical and nontechnical skills. For perioperative teams to identify and maintain clinical competency, well-developed and easy-to-use measures of competency are needed. Methods Tools for measuring the technical and nontechnical performance of perioperative teams were developed and/or identified, and a group of raters were trained to use the instruments. The trained raters used the tools to assess pediatric teams managing simulated emergencies. A psychometric analysis of the trained raters' scores using the different instruments was performed and the agreement between the trained raters' scores and a reference score was determined. Results Five raters were trained and scored 96 recordings of perioperative teams managing simulated emergencies. Scores from both technical skills assessment tools demonstrated significant reliability within and between ratings with the scenario-specific performance checklist tool demonstrating greater interrater agreement than scores from the global rating scale. Scores from both technical skills assessment tools correlated well with the other and with the reference standard scores. Scores from the Team Emergency Assessment Measure nontechnical assessment tool were more reliable within and between raters and correlated better with the reference standard than scores from the BARS tool. Conclusions The clinicians trained in this study were able to use the technical performance assessment tools with reliable results that correlated well with reference scores. There was more variability between the raters' scores and less correlation with the reference standard when the raters used the nontechnical assessment tools. The global rating scale used in this study was able to measure the performance of teams across a variety of scenarios and may be generalizable for assessing teams in other clinical scenarios. The Team Emergency Assessment Measure tool demonstrated reliable measures when used to assess interprofessional perioperative teams in this study.
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- 2021
7. Early experience with PECS 1 block for Port-a-Cath insertion or removal in children at a single institution
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Ban C. H. Tsui, R. J. Ramamurthi, and Farrukh Munshey
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medicine.medical_specialty ,Catheterization, Central Venous ,Adolescent ,Treatment outcome ,Anesthesia, General ,03 medical and health sciences ,0302 clinical medicine ,Port (medical) ,Catheters, Indwelling ,030202 anesthesiology ,Block (telecommunications) ,Medicine ,Humans ,030212 general & internal medicine ,Single institution ,Anesthetics, Local ,Child ,Pain Measurement ,Retrospective Studies ,Pain, Postoperative ,Thoracic Nerves ,business.industry ,General surgery ,Infant ,Nerve Block ,Length of Stay ,Anesthesiology and Pain Medicine ,Postoperative diagnosis ,Treatment Outcome ,Anesthesia ,Child, Preschool ,business ,Vascular Access Devices - Published
- 2018
8. The Role of Sugammadex in Symptomatic Transient Neonatal Myasthenia Gravis: A Case Report
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R. J. Ramamurthi and Jamie E. Rubin
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Male ,medicine.medical_treatment ,Pyloromyotomy ,Pyloric stenosis ,Sugammadex ,03 medical and health sciences ,0302 clinical medicine ,Myasthenia Gravis, Neonatal ,030202 anesthesiology ,medicine ,Humans ,Transient neonatal myasthenia ,030212 general & internal medicine ,Androstanols ,Rocuronium ,Neuromuscular Blockade ,business.industry ,Infant, Newborn ,General Medicine ,medicine.disease ,Myasthenia gravis ,Muscle relaxation ,Treatment Outcome ,Anesthesia ,business ,medicine.drug ,gamma-Cyclodextrins - Abstract
We describe the case of a 3-week-old boy with pyloric stenosis who presented for laparoscopic pyloromyotomy in the setting of symptomatic transient neonatal myasthenia gravis. The patient received muscle relaxation with rocuronium, and neuromuscular blockade was successfully reversed with sugammadex with recovery guided by train-of-four monitoring. He was extubated uneventfully without complications. Because sugammadex binds directly to rocuronium rather than interfering with acetylcholine metabolism, it might provide a good option for reversal of neuromuscular blockade in transient neonatal myasthenia gravis.
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- 2017
9. Local anesthetic pharmacology in pediatric anesthesia
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Elliot J. Krane and R. J. Ramamurthi
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Young child ,business.industry ,Local anesthetic ,medicine.drug_class ,Neuraxial blockade ,Pharmacology ,Anesthesiology and Pain Medicine ,Topical anesthesia ,Anesthetic ,Medicine ,Hemodynamic stability ,business ,Pediatric anesthesia ,medicine.drug - Abstract
In the last 25 years there has been an increase in the use of regional blocks in children. This is due to several converging factors: a better knowledge of the pharmacology of local anesthetic agents in the child, the availability of equipment adapted for children’s anatomy, the recognition of the remarkable hemodynamic stability of the young child during an neuraxial block, as well as the recognition of the need to treat pain not just in the operative period, but in the postoperative period of time as well. The safety of performing regional anesthetic blocks in children depends on the practitioner’s recognition of three important differences between adults and children: (1) their frequent inability to allow the performance of a regional anesthetic block unless under general anesthesia (which is a subject of controversy that is beyond the scope of this review), (2) the anatomic differences between adults and children, and (3) the pharmacologic/pharmacodynamic differences between adults and children. The purpose of this review is to examine the pharmacology of the local anesthetic agents commonly used in children.
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- 2007
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10. Clonidine for the prevention of emergence agitation in young children: efficacy and recovery profile
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Alan R. Tait, Terri Voepel-Lewis, Constance Burke, Shobha Malviya, and R. J. Ramamurthi
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Male ,Methyl Ethers ,medicine.medical_specialty ,Anesthesia, General ,Placebo ,Clonidine ,Sevoflurane ,law.invention ,Postoperative Complications ,Randomized controlled trial ,law ,medicine ,Humans ,Child ,Psychomotor Agitation ,Isoflurane ,business.industry ,Surgery ,Acetaminophen ,Ketorolac ,Anesthesiology and Pain Medicine ,El Niño ,Child, Preschool ,Anesthesia ,Anesthetics, Inhalation ,Injections, Intravenous ,Pediatrics, Perinatology and Child Health ,Female ,Laser Therapy ,Minor Surgical Procedures ,Sleep Stages ,Otologic Surgical Procedures ,business ,Adrenergic alpha-Agonists ,medicine.drug - Abstract
Summary Background: Emergence agitation (EA) is a common postoperative problem in young children who have received sevoflurane and isoflurane for general anesthesia. This randomized, double-blinded study evaluated the efficacy of intraoperative clonidine in reducing EA, and describes its recovery profile. Methods: With Institutional Review Board approval and informed consent, children undergoing brief, minimally painful procedures were studied. All children received preemptive analgesia with acetaminophen and ketorolac, sevoflurane for induction, and isoflurane for maintenance of anesthesia. Children received either 2 lgAEkg )1 clonidine or placebo intravenously (i.v.) following induction of anesthesia. Children were observed postoperatively for behavior and side effects, and their parents were telephoned the next day to determine postdischarge recovery characteristics. Results: One hundred and twenty children were included in this study: 59 of whom received clonidine, and 61 placebo; 41% of those in the placebo group exhibited moderate–severe EA compared with only 22% of those in the clonidine group (P < 0.03). Compared with those who received placebo, children who received clonidine awakened more slowly (22 min vs 14 min), had a longer postanesthesia care unit stay (57 min vs 46 min), and experienced sleepiness more frequently after discharge (75% vs 39%; all comparisons significant at P < 0.03). There were no adverse cardiorespiratory events in either group. Conclusions: Findings demonstrate that i.v. clonidine administered after induction of anesthesia significantly reduces the incidence of EA in young children, but is associated with sleepiness postoperatively.
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- 2006
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11. Improving electrical safety for patients with Epidermolysis bullosa
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R. J. Ramamurthi, Alice A. Edler, and Glenn A. Valenzuela
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medicine.medical_specialty ,Electric Wiring ,business.industry ,MEDLINE ,Equipment Design ,Surgical procedures ,Skin Care ,medicine.disease ,Dermatology ,Electrocardiography ,Anesthesiology and Pain Medicine ,Surgical Procedures, Operative ,Pediatrics, Perinatology and Child Health ,medicine ,Humans ,Epidermolysis bullosa ,Child ,Epidermolysis Bullosa ,business - Published
- 2008
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12. The use of dexmedetomidine during laryngoscopy, bronchoscopy, and tracheal extubation following tracheal reconstruction
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Jeannie L. Seybold, R. J. Ramamurthi, and Gregory B. Hammer
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Male ,Rigid bronchoscopy ,medicine.medical_specialty ,Laryngoscopy ,Deep anesthesia ,Bronchoscopy ,Tracheal extubation ,medicine ,Humans ,Hypnotics and Sedatives ,Dexmedetomidine ,Propofol ,medicine.diagnostic_test ,business.industry ,respiratory system ,Surgery ,Trachea ,Anesthesiology and Pain Medicine ,Child, Preschool ,Anesthesia ,Pediatrics, Perinatology and Child Health ,Female ,business ,Adrenergic alpha-Agonists ,medicine.drug - Abstract
Summary We report the use of dexmedetomidine for laryngoscopy, rigid bronchoscopy, and tracheal extubation in the operating room in two children who had undergone tracheal reconstruction 1 week previously. Dexmedetomidine in combination with propofol provided appropriately deep anesthesia during these brief but stimulating procedures without cardiovascular or respiratory depression.
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- 2007
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13. Regional Anesthesia
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Elliot J. Krane, Artee Gandhi, and R. J. Ramamurthi
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- 2008
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14. Acute gastric distension: a lesson from the classics
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A Tatman and R. J. Ramamurthi
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medicine.medical_specialty ,General Veterinary ,business.industry ,Gastric distension ,Stomach Volvulus ,Pneumothorax ,Tension pneumothorax ,Hernia, Diaphragmatic, Traumatic ,Surgery ,Treatment Outcome ,Child, Preschool ,medicine ,Drainage ,Humans ,Tube (fluid conveyance) ,Female ,medicine.symptom ,business ,Respiratory Insufficiency ,Intubation, Gastrointestinal - Abstract
Acute gastrothorax may masquerade as a tension pneumothorax. Once the diagnosis is suspected, a nasogastric tube should be passed to release the gastric distension and confirm the diagnosis (Fein et al, 1993). This article describes a case where, despite having made the correct diagnosis, the authors were unable to pass a nasogastric tube in a child who was rapidly deteriorating.
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- 2001
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