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Additional file 1: Supplementary Table 1. Clinical characteristics of HNSC patients. Supplementary Table 2. Correlation between overall survival and multivariable characteristics in TCGA patients. Supplementary Table 3. KEGG and GO term correlated with IL17A expression (Top 5). Supplementary Table 4. Correlation analysis between IL17A and relate genes markers of immune cells in HNSC. A TCGA. B GEPIA. Supplementary Table 5. Correlation analysis between IL17A and relate genes top 20. Supplementary Table 6. The genes expression between normal and tumor tissues. A Unpaired samples. Tumor=502, Normal=44. B Paired samples. N=44.

Additional file 2: Figure 1. The expression of IL17A between normal and HNSC tumor tissues(A). The correlations between the levels of IL17A expression and overall survival in HNSCC patients were verified in GEPIA (B) and UCSC Xena (C) online database. Figure 2. Pathway enrichment results for differentially expressed genes between high and low expression of IL17A in HNSC patients from KEGG and GO analysis (A, B). Figure 3. Kaplan Meier survival curves (disease specific survival) comparing the high and low expression of the IL17A correlated 12 genes in HNSC patients (A-L).