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There are different thermal perception models linked to a mathematical thermophysiological human model, with which the thermal sensation under stationary and/or dynamic conditions can be evaluated. Each of these perception and thermophysiological models have their own field of application. Stolwijk developed a thermophysiological human model without an associated thermal perception model, which today is still the basis for other mathematical thermophysiological models. Fiala developed the FPC model, also based on the Stolwijk model, and is one of the latest developments in the field of thermophysiological human models. In the FPC model, an equation is included with which the thermal sensation under stationary and dynamic conditions can be assessed; the so-called Dynamic Thermal Sensation (DTS). The DTS equation is, however, specifically developed for use in combination with the FPC model. In contrast to the Stolwijk model, the source code of the computer programs of the later developed thermophysiological human models is not freely available, which limits the use and applicability of the models in practice. It is precise because of the availability of the source code that the Stolwijk model is still used in industry and the research world. The question, therefore, arises: ‘To what extent can a human transient thermal sensation equation be derived, combined with the Stolwijk model, in a similar way to that used for the DTS equation in the FPC model?’.

Compared with the general population, older adults with immune senescence and individuals who are immunocompromised (IC) due to disease or immunosuppressive therapy are at increased risk for herpes zoster (HZ) and its associated complications, which can be debilitating and life-threatening. Vaccination can be an effective strategy against HZ and studies have shown that HZ vaccination in IC individuals can elicit immune responses and provide protection from infection. Recently, the first approvals have been granted in the United States and the European Union for the recombinant HZ vaccine (RZV) in adults ≥ 18 years of age at risk of HZ due to immunodeficiency or immunosuppression. Existing systematic reviews have highlighted the risks for HZ in limited immunocompromising conditions and have only examined clinical data for RZV. This review details the risks and burden of HZ in a broad range of clinically relevant IC populations and summarizes key efficacy and safety data for RZV and live HZ vaccine in these individuals. Research has shown IC individuals can benefit from HZ vaccination; however, these insights have yet to be fully incorporated into vaccination guidelines and clinical care. Clinicians should consider HZ vaccination in eligible at-risk populations to protect against HZ and its associated complications and thereby, reduce the burden that HZ poses on the healthcare system. Electronic health records and linked personal health records could be used to identify and contact patients eligible for HZ vaccination and provide clinical decision support-generated alerts for missing or delayed vaccinations. This review will help clinicians identify eligible IC individuals who may benefit from HZ vaccination. A video abstract linked to this article is available on Figshare https://doi.org/10.6084/m9.figshare.21517605.

BACKGROUND: Many occupations require workers to stand for prolonged periods, which can cause discomfort, pain and even injures. Some supermarkets in life provide a foot pad for checkout staff to let them stand on it at work, thereby reducing standing fatigue caused by standing for a long time. The inclined platform is the same as the foot pad mentioned above. That is, the staff stepped on it and relieved standing fatigue to a certain extent. OBJECTIVE: The study aims to analyze how the standing angle affects fatigue among prolonged standing workers and tries to find an inclined platform with a specific angle to reduce standing fatigue. METHODS: This experiment studied fatigue of the inclined platforms with different angles on prolonged standing workers, eight participants were selected to participate in the test. The plantar pressures and sEMG (Surface Electromyography) were used to collect the physiological information change of prolonged standing participants in the lower limb and waist. The visual analogue scale was used as a subjective method to measure the psychological fatigue. RESULTS AND CONCLUSION: The study highlights the relationship between standing angle and lower limb fatigue. The inclination of the standing platform has different effects on the participants under different time conditions. When participants stand on inclined platforms at 0°, 5° and 10°, the iEMG (Integrated Electromyography) values of the gastrointestinal muscle were not significantly different until the third sampling point (40 minutes). After that self-regulation of lower limb muscles is better when standing on an inclined platform between 5° and 10°, it has a certain effect on alleviating lower limb fatigue. This knowledge is crucial for the design of the inclined working platforms fitting the needs of prolonged standing workers.

(Dis)comfort research that has no information on behaviour of the participants can be considered as incomplete, as major influencing factors could be missed. For (dis)comfort research it is important to capture factors such as context, task/activity, posture, movement, (distracting) stimuli and time, as these factors have influence on the experienced (dis)comfort. Recording the behaviour allows for better evaluation of and comparison between studies, contributing to an increase of scientific knowledge on (dis)comfort.

After decades of research and development, haptic feedback is increasingly appearing in consumer products. While the prevalence of haptic feedback is increasing, the integration rarely offers increased fidelity to previous generations. We argue this is because of the tremendous complexity of successful haptic design engineering, but critically, also because of information saturation. With novel cutaneous feedback technologies and companies emerging almost daily, the multi-disciplinary nature of haptics and the marketing-driven terminology used to stand out in a crowded market makes it challenging to select and integrate actuators correctly. To manage this complexity and facilitate the interdisciplinary exchange of user requirements and material affordances, we introduce a novel classification criterion for haptic actuators focused on the bandwidth and fidelity of potential effects. We introduce vocabulary for describing the precise experience the actuators and corresponding systems should deliver. Lastly, we summarize currently commercially available cutaneous-based haptic technology. In the nearby future, the same criterion and language can also prove valuable for steering technology development of new and improved actuators and enabling novice and experienced practitioners to understand and integrate cutaneous feedback in their products.

The purpose of this study is to research if a headrest benefits the comfort of the passenger and lowers muscle activity in the neck when sitting in a reclined (slouched) posture while watching in flight entertainment (IFE) in an aircraft business class seat. No significant differences in muscle activity in the musculus sternocleidomastoid and musculus trapezius pars descendant were found between the conditions with headrest and without headrest. A significant difference in expected comfort rating was found. Subjects indicated they expect to experience more comfort with a headrest when watching IFE for a duration of two movies during a long-haul flight. This study also found a significant difference in posture. In the condition without headrest the head was more upright compared to the condition with headrest. The lack of significant difference in muscle activity and the significant difference in posture may indicate that humans tend to look for a head position that is neutral, in the sense of minimal muscle effort. This study shows that the use of a headrest may benefit the comfort experience of the passenger during flight. However, further research is necessary on the design of the headrest and the long-term effects of head support on comfort, discomfort, muscle activity and fatigue for watching IFE in a slouched posture.

The purpose of this study is to construct an aircraft seat discomfort scale and verify the evidence of its validity and reliability. We developed a questionnaire and presented it to 1500 Brazilian passengers at an airport. The data analysis included: 1) factor analysis; 2) the analysis of the items to be used in the scale created using Item Response Theory. The scale covered all levels, from "without discomfort" to "maximum discomfort". At the level of minimal, a passenger feels that the aircraft seat is cramped and has little space. Discomfort tends to increase when passengers are unable to perform desired activities (eg: reading, sleeping), which causes irritation and disappointment. The maximum discomfort level occurs when noise disrupts activities and an aircraft seat is considered hard. The scale developed presented indications that it is reliable and valid, proving to be a useful tool for identifying levels of discomfort in aircraft seats.

Interferences during the boarding procedure are one of the main reasons of delay and increased turnaround time, becoming a relevant problem for airlines. Observations of the boarding process and questionnaires inside the aircraft revealed three main bottlenecks during the boarding process: (1) Hand luggage: Storage space is not sufficient and/or not used efficiently; (2) Preparation: Passengers are not well prepared for the boarding process; and (3) Communication: Audio announcements are unclear and unfocused. By translating these bottlenecks as possibilities for improvement, solutions were designed for the airport and aircraft interiors to reduce boarding time and improve the passenger boarding experience. Concepts ranged from an app to scan your hand luggage at home and make a reservation for overhead bin space; to a redesigned waiting area to help passengers prepare for boarding; to new boarding methods and redesigned aircraft seats. In this paper, several design concepts are presented in more detail.

Background The adjuvanted recombinant zoster vaccine (RZV) has demonstrated >90% efficacy against herpes zoster in adults ≥50 years of age and 68% efficacy in autologous hematopoietic stem cell transplant recipients ≥18 years of age. We report the immunogenicity and safety of RZV administered to patients with solid tumors (STs) before or at the start of a chemotherapy cycle. Method In this phase 2/3 observer-blind, multicenter study (NCT01798056), patients with STs who were ≥18 years of age were randomized (1:1) to receive 2 doses of RZV or placebo 1-2 months apart and stratified (4:1) according to the timing of the first dose with respect to the start of a chemotherapy cycle (first vaccination 8-30 days before the start or at the start [±1 day] of a chemotherapy cycle). Anti-glycoprotein E (gE) antibody concentrations, gE-specific CD4+ T cell frequencies, and vaccine response rates (VRRs) were assessed 1 month after dose 1 and 1 and 12 months after dose 2. Reactogenicity and safety were assessed in the total vaccinated cohort through 12 months after dose 2. Results There were 232 participants in the total vaccinated cohort, 185 participants in the according-to-protocol cohort for humoral immunogenicity, and 58 participants in the according-to-protocol cohort for cell-mediated immunogenicity. Postvaccination anti-gE antibody concentrations, gE-specific CD4+ T cell frequencies and VRRs were higher in RZV recipients than in placebo recipients. Solicited adverse events (AEs) were more frequent among RZV recipients than placebo recipients. Incidence of unsolicited AEs, serious AEs, fatalities, and potential immune-mediated diseases were similar between RZV and placebo recipients. Conclusion RZV was immunogenic in patients with STs receiving immunosuppressive chemotherapies. Humoral and cell-mediated immune responses persisted 1 year after vaccination. No safety concerns were identified.

Immunocompromised (IC) persons are at increased risk for herpes zoster (HZ) and its complications, mainly due to impairment of cell-mediated immunity (CMI). The adjuvanted recombinant zoster vaccine (RZV) demonstrated efficacy against HZ in autologous hematopoietic stem cell transplant (auto-HSCT) recipients and hematologic malignancy (HM) patients. We review immune responses to RZV in 5 adult IC populations, 4 of which were receiving multiple, concomitant immunosuppressive medications: auto-HSCT and renal transplant recipients, HM and solid tumor patients, and human immunodeficiency virus-infected adults. Although administered in most cases when immunosuppression was near its maximum, including concomitantly with chemotherapy cycles, RZV induced robust and persistent humoral and, more importantly, CMI responses in all 5 IC populations. Based on the overall clinical data generated in older adults and IC individuals, RZV is expected to provide benefit in a broad adult population at risk for HZ.

For designing large-scale products like an airplane, engaging end-users in the concept phase is difficult. However, early user evaluation is important to choose the path which fits the user’s needs best. In particular, comfort-related assessments are difficult to conduct with digital models that are shown on a desktop PC application. Digital Human Modelling (DHM) plays a role in postural comfort analysis, while the subjective comfort feedback still largely relied on consulting with end-users. This paper applies a human-centered design process and analyses the advantages and disadvantages of using VR prototypes for involving users during concept design. This study focused on using VR prototypes for concept selection and verification based on comfort assessment with potential end-users. The design process started with an online questionnaire for identifying the quality of the design elements (Step 1 online study). Then, alternative concepts were implemented in VR, and users evaluated these concepts via a VR headset (Step 2 Selection study). Finally, the research team redesigned the final concept and assessed it with potential users via a VR headset (Step 3 Experience study). Every design element contributed positively to the long-haul flight comfort, especially tap-basin height, storage, and facilities. The male and female participants had different preferences on posture, lighting, storage, and facilities. The final prototype showed a significantly higher comfort rate than the original prototypes. The first-person immersion in VR headsets helps to identify the nuances between concepts, thus supports better decision-making via collecting richer and more reliable user feedback to make faster and more satisfying improvements.

During recent decades, the educational outcomes of the children of immigrants have been extensively studied, with a growing emphasis on the heterogeneity of the so-called second generation. Yet, the impact of host country citizenship on children's educational outcomes has only received limited attention so far, although children of immigrants do not get automatic birthright citizenship in most European countries. Focusing on the Netherlands, this paper compares educational trajectories among citizen and non-citizen children of immigrants. Register data and sequence analysis are used to map and cluster the trajectories of a full cohort of second-generation students from the start of secondary school. We apply a variant of optimal matching focusing on sequences of transitions, which enables us to uncover different patterns of (im)mobility within a stratified school system better than the standard approach. Multinomial logistic regressions show that students who acquire Dutch citizenship are significantly more likely to follow upward trajectories, taking advantage of the system's flexibility and “back doors”. Conversely, not having Dutch citizenship is associated with a higher risk of dropout and school interruptions. These findings are in line with our theoretical expectation that, during the naturalisation process, parents acquire or further develop important resources for navigating a complex educational system such as the Dutch one.

First Published May 3, 2021 Whereas the so-called ‘citizenship premium’ in the labour market has been widely studied, we know little about how naturalisation affects immigrants’ lives beyond work and income. Focusing on the Netherlands, this paper analyses the relationship between citizenship acquisition and immigrant residential mobility, in particular the propensity of immigrants to move away from areas with high concentrations of migrants. We draw on register data from Statistics Netherlands (N = 234,912). We argue that possessing Dutch citizenship reduces spatial stratification by diminishing the risk of housing market discrimination, thereby facilitating mobility outside of migrant-concentrated areas. Our findings show that naturalised immigrants are 50% more likely to move out of concentrated neighbourhoods, all else constant. The effect of naturalisation is especially relevant for renting without housing benefits and for home ownership, and for mid-risk immigrants who earn around the median income and hold permanent jobs, whose applications face strong scrutiny from landlords, rental agencies and mortgage lenders.

A proper seat is crucial not only for preventing health issues but also for the (dis)comfort perception. In the design of a seat, the seat pan’s geometric shape, either in or under the cushion, plays a vital role as it constrains the deformation of the foam it supports. The contact area and pressure distributions between the foam and the human body, closely associated with (dis)comfort, are influenced by those constrained deformations. In this paper, using a comparative study, the aim is to determine if opportunely shaped seat pans are better than a standard flat pan regarding postural comfort and pressure distribution. Two cushions with the same type of foam but two different seat pans were used in the comparison. The first seat pan is the standard one used in current aircraft seats and the second is a shaped seat pan, which was designed following the mean buttock-thigh shape of an international population (including P5 females and P95 males). Twenty-two international participants (11 males and 11 females, with BMI between 16 and 30) took part in the blind experiment. Results indicated that the cushion with shaped seat pan performed better as it led to less postural comfort, a larger contact area and more uniform pressure distribution. Also, 64% of participants favored the cushion with the shaped seat pan as they felt it was more comfortable and suitable for the buttock shape.

BACKGROUND: Scents may influence the perceived comfort of an environment. There are only a few studies conducted on the relationship between scent and comfort in aircraft cabin. OBJECTIVES: The goal of this research is to explore whether relationships between scents and perceived comfort can be found for passengers in an aircraft cabin. METHODS: 276 participants joined an experiment in a Boeing 737 fuselage. The participants were divided into nine groups and each joined a session for 60 minutes with the exposure to different scents. The effect of the odor was measured by a set of questionnaires at the beginning and at the end of the session. Results of questionnaires were analyzed regarding the effects on the completion time, of the type of scents, of the intensity of the scent and on gender. RESULTS: Significant differences were found at the beginning and at the end of the experiment regarding comfort and emotion, but sometimes no relations could be established. The influence of different scents on comfort/discomfort varied and changed over time. However, in all scenarios, participant’ scores on emotion decreased. Additionally, the added scents influenced the linearity between the changes in comfort and discomfort. CONCLUSIONS: Smell could influence the perceived comfort/discomfort of aircraft passengers over time, and different types of smells have different effects on passengers. The preferences on scents are diverse, which highlights the need for personalization in aircraft cabin design.

Soteria is a patient transporting drone, which is part of a living lab setting for Future Mobility, which Embraer is developing. It has been designed in conjunction with the Talaria propulsion system, an autonomous and modular eVTOL flight package. The idea is that during disaster scenarios, Soteria is summoned by first responders to the scene after which a noncritical patient is loaded from the field into the carrier. Soteria then autonomously and independently ferries the patient safely to the closest hospital, where they are unloaded by medical personnel. It is important that handlings are fast and that the patient will fit in the system. Therefore, Soteria was ergonomically tested. The interior of the carrier, the interior layout, and human-machine interface were evaluated with a 1:1 model and compared with guidelines found in the literature. Based on that improvements were made and presented for future design iterations.

This study aims to collect data on the activities, postures, dis(comfort), and needs of train passengers. Observations in the trains and questionnaires completed by train passengers were used. The online questionnaire was completed using the smartphone of the passengers during the train trip. The most often observed activity of the passengers was using a smartphone while travelling. They used a smartphone to listen to music, chat or type, look at a video or picture, and to read. Most passengers reported that they hold a smartphone with both hands and used a smartphone with the right hand also. The thigh support and the armrests of the seat showed the lowest comfort and certainly have room for improvement. Future research could be considered to design the seat to increase passenger comfort while using a smartphone.

BACKGROUND: The Human-Centered Design methodology advocates VR prototyping, as an effective tool to evaluate concepts in a cost-efficient, time-saving way. It is the question of whether it works in the development of a product intended to increase privacy while flying. OBJECTIVE: The current study aims at the application of virtual reality on the evaluation of a new privacy bubble called PRIVA for the passenger cabin. METHODS: An interactive VR was created and aligned with the HTC VIVE headset. 40 participants took part in the experiment as well as in the post-experiment survey. RESULTS: The concept was in overall, desirable as it was perceived to be more private, comfortable, satisfactory, effective, and appealing to participants compared to the current seat experiences. It was also perceived as more satisfactory with regards to the activities. CONCLUSIONS: The VR was effective, although there are limitations, the product seems promising and should be developed further.

This study investigates the tactile perceived seat-human interaction of four types of BMW 5-series seats with the same foam properties and contours but different seat cover and seat suspension properties; 38 healthy subjects participated in an experiment rating and ranking the tactile perceived properties of the seats while blindfolded. A discomfort test, a seat characterizing rating on a scale of word pairs, and the overall experience of the seats were examined in four different sitting positions. The results of the experiment were related with the outcome of an objective measurement method: a pressure measurement mat and the measurement tool of Wegner et al. [19]. The study showed that the perception of the surface while interacting with the seat is independent from the sitting position. In contrast, the perception of the hardness and the elasticity of the seat is position-dependent. The results of the seat characterization are in line with the results of the measurement tool of Wegner et al. [19]. Further research is needed to investigate the mutual interdependence of the various measurement points of the measurement tool and to improve the prediction accuracy of the seat characteristics.

AIMS AND OBJECTIVES: To study practice in consciousness assessment among neuroscience nurses in Europe.BACKGROUND: Over the years, several instruments have been developed to assess the level of consciousness for patients with brain injury. It is unclear which instrument is being used by nurses in Europe and how they are trained to use these tools adequately.DESIGN/METHODS: A cross-sectional questionnaire, created by the European Association of Neuroscience Nurses Research Committee, was sent to neuroscience nurses in 13 European countries. The countries participated in 2016 with a response period of 3 months for each country.RESULTS: A total of 331 questionnaires were completed by nurses in 11 different countries. Assessment of consciousness was part of the daily routine for a majority of bedside nurses (95%), with an estimated median frequency of six times per shift. The majority uses a standardised instrument, and the Glasgow Coma Scale is the most common. Most participants assess consciousness primarily for clinical decision-making and report both total scores and subscores. The majority was formally trained or educated in use of the instrument, but methods of training were divers. Besides the estimated frequency of assessments and training, no significant difference was found between bedside nurses and other nurse positions, educational level or kind of institution.CONCLUSION: Our study shows that consciousness assessment is part of the daily routine for most nurses working in neurology/neurosurgery/neurorehabilitation wards in Europe. The greatest variation existed in training methods for the use of the instruments, and we recommend standardised practice in the use of assessment scales.RELEVANCE TO CLINICAL PRACTICE: In clinical practice, both managers and staff nurses should focus on formalised training in the use of assessment tools, to ensure reliability and reproducibility. This may also increase the professionalism in the neuroscience nurses' role and performance.

The study of ergonomics and (dis)comfort is a major topic of interest to scientific literature since the introduction of ISO 11228. Over the past 30 years, researchers have attempted to understand the mechanisms underlying perceptions of (dis)comfort for a seated subject. Three main factors are recognized as paramount for the comfort performance of a seat: human body posture, pressure at interface, and load distribution on the contact area; this study investigates the relationships between them and examines their significance for (dis)comfort perception. Physiological factors are known to play a role in (dis)comfort perception, and we consider these as a consequence of the three main parameters above. An explanation is given for this hypothesis. Experimental tests were conducted using a school chair with a rigid seat pan and no armrests for reducing the number of factors of influence. Conclusions show the levels of correlation between acquired information and perceived (dis)comfort.

There is certainly room for economy-class travelers to make their trips more pleasant. A travel pillow might improve comfort. In this study, the comfort expectations and experience of travel pillows were examined. Comparing these 2 aspects indicated that it is not always possible to predict the comfort experience associated with a product based on a picture, and that there is a discrepancy between expected and experienced comfort. Experienced comfort is highest for travel pillows that restrict head movements in all directions in order to maintain a neutral posture. The results of this study also support earlier studies that suggested that discomfort experience can be predicted by observing the number of participants’ in-seat movements; more movements result in higher experienced discomfort.

The notion that naturalisation matters for the economic integration of immigrants is well established in the literature, but why and to whom that is, remains surprisingly ambiguous. The citizenship premium is traditionally assumed to result from increased labour market access and positive signalling towards employers, but these mechanisms fail to explain increased earnings derived from paid employment, which has been the predominant focus in most studies. We argue that naturalisation needs to be understood in the context of the life course, as immigrants anticipate rewards and opportunities of citizenship acquisition by investing in their human capital development. Insofar as naturalisation subsequently leads to higher earnings, we expect that the citizenship premium mostly reflects better employment opportunities rather than access to better paying jobs. To test these assumptions, we use high-quality register data from Statistics Netherlands, covering the period 1999–2011. These data contain almost all registered foreign-born individuals in The Netherlands (N = 74,531) and allow us to track immigrant cohorts over time. Results show that naturalisation confers a one-time boost in earnings after naturalisation, but particularly for migrants from economically less developed countries and unemployed migrants. Furthermore, earnings develop faster leading up to naturalisation than afterwards, consistent with the notion of anticipation. The relevance of citizenship for employed immigrants in part results from an increase in working hours, but is not explained by variation in labour market sectors. We conclude that citizenship matters in terms of earnings from labour, but that its impact is not universal and manifests predominantly leading up to naturalisation.

Today, there is a significant amount of research projects focusing on human health and well-being and the connection between the environment and human psychological responses. A holistic approach to integrating control room communications with comfortable interiors is emerging. This paper discusses the socio-cultural aspects of comfort and the sensory communication aspects of environmental comfort design for future control room interiors.

In this paper adaptive customization by color changing LEDs is investigated. Two forms of customization are studied: one system reacts on the color of subjects’ clothes and one system was influenced by a color blending App. Both are built up in a real car. The emotional responses were recorded before and after the test with 70 subjects. Emotions as attraction, hope and joy were found as reactions and 58.6% preferred this approach of steering the interior lighting. Half of the sample preferred the color mixing and half the automatic color detection system showing that there are two clear interaction preferences. The expectations recorded prior to the test influenced the level of experience massively and also interfered with the subjects’ emotions.

Before fatigue caused by the driving task becomes a safety threat, it already has a negative effect on well-being. Therefore, it is desirable to intervene in an early stage of the fatiguing process to decrease the perceived load from a monotonous driving task and to create a more pleasurable driving experience. Enhancing driver vigilance could also create a competitive advantage for the car manufacturer. This paper reviews the existing body of knowledge concerning driver fatigue theories and countermeasures against driver fatigue. Current (automotive) features concerning fatigue are also evaluated. A fatigue countermeasure system should measure and/or predict fatigue, intervene with a stimulus and subsequently restore performance and alertness. A distinction can be made between physical and cognitive fatigue. Physical fatigue results mainly from static sitting issues. This type of fatigue can be countered with micro-movements and the stimulation of postural change. Cognitive fatigue can be further divided into task-related and sleep-related fatigue. Fatigue resulting from task overload can be countered with automation and assist systems. Fatigue from task underload can be countered with a variety of stimulation. Sleep-related fatigue is considered intervention resistant by some researchers, although it also seems to be possible to manipulate the circadian rhythm with blue light.

Comfort experiences are not caused by a single factor, but are the result of diverse components such as postures, cognitive- and emotional experiences, as well as a person’s activity. The present empirical study investigated the experienced comfort of car passengers in the rear seat. We varied typical car passengers’ activities such as listening to music, working, and looking out the window. Dependent variables were the passenger’s comfort rating, his emotional valence- and arousal-related experience, his heart rate, and his seating position. The results (N = 23/16) showed that music positively influences comfort experiences. Moreover, correlation analysis between the dependent variables showed that comfort was significantly correlated only to the positive emotional valence component, and not to more physiological components such as emotional arousal, heart rate or seating position. The results suggest that car designers can improve the comfort of rear passengers by focussing on music and emotion design in contrast to the more conventional approach of physical ergonomics.

The percentage of passengers that prefer travelling in groups is increasing. In most vehicles, passengers sit side by side and need to turn their body to be engaged in the conversation with their fellow travellers. However, rotating the body could lead to discomfort which influences conversation quality. The aim of this research is to study the effect of seat configuration on the (dis)comfort experience, conversation quality and posture. Experiments in which participants were asked to talk to each other while sitting at the same distance (1 m) were conducted in four seating arrangements (with seat-belts on), where the angle between the forward directions of two seats were positioned at 0° (side by side), 22.5°, 90° and 120° (almost opposite each other), respectively. Optical tracking has been deployed and the collected data were processed with MatLab

This paper gives an overview of the relevance of the comfort concept, its definitions, boundary conditions, and stakeholders. Current comfort theories are presented and reflected on, both in their applicability and testing methodology. Questionnaires commonly used to study comfort and discomfort are also reviewed. An example of a comfort lab is introduced in its functionality and tools, which can be useful as a benchmark for others studying comfort.

Purpose The purpose of this study is to examine the differences in pressure sensitivity for areas of the human body in contact with the seat pan and backrest of a vehicle seat. These could provide a theoretical base for adapting the softness of the foam or the flexibility components used in seat design. Methods Sensitivity was recorded at 32 points touching the seat pan and backrest by pushing a cylinder with a diameter of 20 mm into the seat until the participant reported that they were no longer comfortable. The force at which discomfort was reported was recorded using an advanced force gauge. Results and conclusions The area of the body having contact with the front of the seat pan was more sensitive than the rest of those parts touching the seat pan. The area of the seat touching the shoulders was significantly more sensitive than the area in between the shoulders and lower down the back. Translating these findings directly into seat design should be done with care. Tests are still needed to confirm the assumed relationship between sensitivity and foam softness. Further information is also needed regarding the complete use of a seat, including analysis of vibrations while driving and comfort during ingress and egress.

In recent years, methods that allow for an objective evaluation of perceived comfort, in terms of postural, physiological, cognitive and environmental comfort, have received a great deal of attention from researchers. This paper focuses on one of the factors that influences physiological comfort perception: the temperature difference between users and the objects with which they interact. The first aim is to create a measuring system that does not affect the perceived comfort during the temperatures' acquisition. The main aim is to evaluate how the temperature at the human-mattress interface can affect the level of perceived comfort. A foam mattress has been used for testing in order to take into account the entire back part of the human body. The temperature at the interface was registered by fourteen 100 Ohm Platinum RTDs (Resistance Temperature Detectors) placed on the mattress under the trunk, the shoulders, the buttocks, the legs, the thighs, the arms and the forearms of the test subject. 29 subjects participated in a comfort test in a humidity controlled environment. The test protocol involved: dress-code, anthropometric-based positioning on mattress, environment temperature measuring and an acclimatization time before the test. At the end of each test, each of the test subject's thermal sensations and the level of comfort perception were evaluated using the ASHRAE (American Society of Heating, Refrigerating and Air-Conditioning Engineers) scale. The data analyses concerned, in the first instance, correlations between the temperature at the interface and comfort levels of the different parts of the body. Then the same analyses were performed independently of the body parts being considered. The results demonstrated that there was no strong correlation among the studied variables and that the total increase of temperature at interface is associated with a reduction in comfort.

Contains fulltext : 177318.pdf (Publisher’s version ) (Open Access) The Nociception Coma Scale is a nociception behaviour observation tool, developed specifically for patients with disorders of consciousness (DOC) due to (acquired) brain injury. Over the years, the clinimetric properties of the NCS and its revised version (NCS-R) have been assessed, but no formal summary of these properties has been made. Therefore, we performed a systematic review on the clinimetric properties (i.e. reliability, validity, responsiveness and interpretability) of the NCS(-R). We systematically searched CENTRAL, CINAHL, Embase, PsycInfo and Web of Science until August 2015. Two reviewers independently selected the clinimetric studies and extracted data with a structured form. Included studies were appraised on quality with the COSMIN checklist. Eight studies were found eligible and were appraised with the COSMIN checklist. Although nearly all studies lacked sample size calculation, and were executed by the same group of authors, the methodological quality ranged from fair to excellent. Important aspects of reliability, construct validity and responsiveness have been studied in depth and with sufficient methodological quality. The overview of clinimetric properties in this study shows that the NCS and NCS-R are both valid and useful instruments to assess nociceptive behaviour in DOC patients. The studies provide guidance for the choice in NCS-R cut-off value for possible pain treatment and cautions awareness of interprofessional differences in NCS-R measurements. SIGNIFICANCE: This systematic review provides a structured overview of the clinimetric properties of the Nociception Coma Scale (-Revised) and provides insights for a solid evidence-based nociception behaviour assessment and treatment plan.

The impact of alternate routes of vaccine administration, subcutaneous (SC) or intramuscular (IM), on the safety and immunogenicity of herpes zoster subunit candidate vaccine (HZ/su) was assessed in Japanese adults aged ≥ 50 y. During this phase III open-label study, 60 subjects were randomized (1:1) to receive HZ/su through SC or IM routes in a 0, 2 month schedule. Vaccine response rates (VRRs) and geometric mean concentrations (GMCs) of varicella zoster virus glycoprotein E (gE)-specific antibodies were determined by ELISA. Solicited and unsolicited symptoms were recorded for 7 and 30 d after each vaccination and graded 1–3 in severity. Serious adverse events (SAEs) were recorded throughout the study. At one month post-dose 2, VRRs were 100% (95% Confidence Interval (CI): 88.1–100) in both groups; anti-gE antibody GMCs were 44126.1 mIU/ml (95% CI: 36326.1–53601.0) and 45521.5 mIU/ml (95% CI; 37549.5–55185.9) in the SC and IM groups, respectively. Injection site reactions (pain, swelling and redness) were common, and observed more frequently following SC administration. Grade 3 redness and swelling were more frequently observed after SC administration. Fatigue and headache were the most frequently reported general symptoms for both routes of administration. Ten and 7 unsolicited AEs were reported in the SC and IM group, respectively. Two unsolicited AEs (1 in SC; 1 in IM) were considered related to vaccination by the investigator. Three non-fatal SAEs considered unrelated to vaccination were reported during the study. Administration of the HZ/su vaccine candidate resulted in a substantial immune response that was comparable between SC and IM subjects, but local reactogenicity may be greater for SC.

Background Aircraft passenger comfort experience was previously defined based on its underlying thematic components representing passengers' perception of the environmental elements and their link to their concerns. Objective This paper aims to 1) identify aircraft passengers' attitudes towards their personal and shared space in the cabin environment during the flight which are linked to their comfort experience and 2) highlight passenger concerns associated with those attitudes. Method A sample involving 16 participants was conducted, collecting full accounts of their real-time flight experiences onboard commercial aircrafts, using questionnaires. Results Four types of attitudes were identified in reaction to participants' personal and shared space during the flight. Those were described as adjust, avoid, approach, and shield. Passengers' concerns associated with those attitudes were respectively: control, privacy, connectedness and tolerance. Conclusions It is concluded that passenger comfort can be improved once the identified concerns and attitudes are addressed in the design of the aircraft seat and interior. Design recommendations are provided accordingly.

Within this special issue, different aspects of the environment are studied: aspects that are distant from the human body, close to the body and touching the human body. Consequently, different human senses are involved in these studies as well as the different consequences and effects on the brain and human behaviour. This special issue also highlights many remaining questions about the effects and relationships between environments and human beings and the need for more studies and research. In particular, future studies are needed that address long-term effects and the effects of the combinations of elements which provide comfort or discomfort.

BACKGROUND The original Stolwijk model is not equipped with clothing, thermal sensation, comfort indices, individual characteristics and performance loss models. OBJECTIVE This study attempts to modify the model to include clothing, thermal sensation as well as the calculation of the percentage of dissatisfied as a result of general discomfort. The model is useful for the evaluation of thermal comfort in the built environment by professionals. METHODS Methods described in literature with regard of clothing, the research of Fiala as well as some in the literature recommended and validated adjustments, to improve the simulation of the skin temperature per body segment, are implemented in the here assembled Stolwijk computer model. Finally, for verification of the above adjustments, the model was compared with experiments conducted in the field of thermal sensation at various levels of temperature change. RESULTS By improving the simulation of the skin temperature per body segment and by adding clothing and thermal sensation, suitable for the assessment of steady state and transient thermal conditions, and fixed with this the percentage of dissatisfied, the scope of the Stolwijk model has become larger than it was before. CONCLUSION On the basis of the calculations and the experimental results, it was concluded that the adjusted Stolwijk model was suitable for the simulation of the thermal sensation under steady state and transient thermal conditions.

Background Passive posture variation in vehicles could enable variation in pressure distribution and muscle activity to counter physical fatigue from static seating resulting in more comfort. The difference in posture, however, should not lead to perceived discomfort and aspects of driving should be considered such as operating the steering wheel, pedals and vision in the mirrors. Objective This study sets out to find out how much postural variation occurs during the driving task and how sensitive is the human body to these changes. Methods The first experiment was user evaluation and assessed how and when the changes in seat configuration were noticeable to the human body. The second experiment evaluated the influence of varying inclination of the backrest and the seat pan by the rating of typical aspects of driving. Results The differences in seat configuration during experiment 1, were so small that there was no consistency in the ratings for the same configuration. The most critical feature that restrains the posture is the location of the rear view mirror. Conclusions The range-of-motion is defined as -1° to +1° for the seat pan and 0° to +1.5° for the backrest based on the results of experiment 2 because of the restraints of the driving task.

BACKGROUND Designers develop their basic competences during their design education and these competences are later amplified and refined during their professional career. Therefore, one could expect that the design processes of professionals and of student designers are conducted differently, and that these processes consist of different components (steps, actions, methods, tools, etc. used in the design process). OBJECTIVE The differences and similarities between the design processes of design students and professionals were studied. In addition the effect of the designers experience on the design process is studied. METHODS The design processes of seating products of 19 professional designers, 15 master students and 16 bachelor students were compared in order to understand the differences in the components they apply in their design process. RESULTS The results showed significant differences between professional designers and design students for eight out of fifteen of the components. The components for which differences were found were applied more frequently by professionals than by students. For six of the components significant positive correlations were found with the designer's experience. CONCLUSIONS There are significant differences between the design processes of design students as well as similarities. The differences amongst others related to the designers' experience.

Evidence Based Practice leeft: ruim 2850 verpleegkundigen deden mee aan Nursings EBP Kennistest. In dit artikel vind je de resultaten, en de uitleg bij tien stellingen. Opvallend is de gemiddelde score van 60 procent. Veel verpleegkundigen doen dus graag mee met EBP, maar kunnen ze echt feiten van fabels onderscheiden?

Most research on product comfort focuses exclusively on the use of the evaluated product (e.g., Kyung, Nussbaum, & Babski-Reeves, 2008; Harih & Dolšak (2013). We sought to investigate the influence of a sitting precondition on ratings for first impression of comfort, short-term comfort, and discomfort of a product. The aim was to assess if and how sensations experienced prior to product use affected product evaluation. Therefore, a vehicle seat was evaluated with two preconditions in a within-subjects design. The comfort model of Vink and Hallbeck was extended according to the findings of this study.

To save fuel costs, lightweight designs and materials are preferred for aircraft interiors. One of the challenges for aircraft seats is to reduce weight without compromising passenger comfort, or perhaps even while increasing comfort. This case study describes three different projects on lightweight designs for aircraft seats, using three-dimensional (3D) scanning methods (Franz, Kamp, Durt, Kilincsoy, Bubb, & Vink, 2011) to determine the ideal seat contour following the human body. The first project on upright sitting in an economy aircraft seat (Hiemstra-van Mastrigt, 2015) set out to collect imprints of the human body in a vacuum mattress by using a handheld 3D scanner to scan the body imprints and obtain a 3D surface. Subsequently, the different scans were superimposed in such a way that differences between the scans were minimized. Based on this “ideal curvature,” an adjustable seat pan concept was developed (Kuday, 2018). A similar 3D scanning method was applied in two other projects: first, developing a prototype for passengers sleeping sideways in a premium economy class aircraft seat (Lam et al., 2014) and, second, a human contour-based business class seating concept (Smulders et al., 2016). This case study concludes with advantages and recommendations for applying 3D scanning in similar projects.

In this paper a measurement tool is described and tested to evaluate the characteristics of different elements of a seat. Many studies report a relationship between discomfort and pressure distribution, but it is unknown what exactly is happening in the interaction. The purpose of this study is to present a measuring device, which records the comfort relevant seat parameters pressure and elongation while loading a seat. The results of the study, including the repeatability, reproducibility and detectability show that the measurement method is appropriate for our purpose, although the reproducibility has to be improved by operator experience or by a more intuitive assembling of the measurement setup. An application example illustrates that the interaction of the seat components highly affect the resulting comfort relevant parameters. The question is whether this objectively recorded differences are also experienced by seat occupants, which is interesting to study in future research.

This study investigates the tactile perceived influence of seat covers. Two identical BMW 3-Series seats are used, one with a leather cover and one with a fabric cover. Thirty healthy subjects participated in an experiment rating the tactile perceived properties of the seats while blindfolded. A discomfort test, a word pair rating and the overall experience of the seats were examined. The study has shown that not only the foam properties and the contour of the seat influences the seat characterisation but also the seat cover material. The leather and the fabric seats were characterised different, but the pressure distribution did not show so much differences. Furthermore, the perceived differentiation of the seats are distinctive for the seat pan and for the backrest. Therefore, further research is needed to investigate other characteristics of the seat like shear force related to various cover properties in combination with different seat components and contour combinations.