1. Effect of Respiratory Impairment on the Outcomes of Primary Percutaneous Coronary Intervention in Patients With ST-Segment Elevation Myocardial Infarction and Coronavirus Disease-2019 (COVID-19)
- Author
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Lara Faggi, Michele Senni, Giulio Guagliumi, Luigi Fiocca, Paolo Canova, Irene Pescetelli, Angelina Vassileva, Dario Pellegrini, Pellegrini, D, Fiocca, L, Pescetelli, I, Canova, P, Vassileva, A, Faggi, L, Senni, M, and Guagliumi, G
- Subjects
Male ,medicine.medical_specialty ,Time Factors ,medicine.medical_treatment ,Acute myocardial infarction ,030204 cardiovascular system & hematology ,Coronary revascularization ,Risk Assessment ,Percutaneous coronary intervention ,03 medical and health sciences ,0302 clinical medicine ,Risk Factors ,Cause of Death ,Internal medicine ,SARS-COV2 ,medicine ,Humans ,Hospital Mortality ,Prospective Studies ,030212 general & internal medicine ,Myocardial infarction ,Lung ,Aged ,Cause of death ,Aged, 80 and over ,Ejection fraction ,business.industry ,Respiration ,COVID-19 ,General Medicine ,Middle Aged ,medicine.disease ,Thrombosis ,Treatment Outcome ,Respiratory failure ,Conventional PCI ,Cardiology ,ST Elevation Myocardial Infarction ,Female ,Acute coronary syndrome ,Respiratory Insufficiency ,Cardiology and Cardiovascular Medicine ,business ,TIMI - Abstract
Background: Coronavirus Disease-2019 (COVID-19) may impair outcomes of patients with ST-segment elevation myocardial infarction (STEMI). The extent of this phenomenon and its mechanisms are unclear. Methods and Results: This study prospectively included 50 consecutive STEMI patients admitted to our center for primary percutaneous coronary intervention (PCI) at the peak of the Italian COVID-19 outbreak. At admission, a COVID-19 test was positive in 24 patients (48%), negative in 26 (52%). The primary endpoint was in-hospital all-cause mortality. Upon admission, COVID-19 subjects had lower PO2/FiO2 (169 [100–425] vs. 390 [302–477], P
- Published
- 2021
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