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BACKGROUND The Korea National Cancer Screening Program currently provides screening for colorectal cancer (CRC) for adults older than 50 years with no upper age limit. In general, people are likely to only pay attention to the benefits of cancer screening and to neglect its risks. Most consider the benefits of cancer screening as being far greater than the risks and are unaware that any potential benefits and harms can vary with age. AIM To report acceptance of an upper age limit for CRC screening and factors associated therewith among cancer-free individuals in Korea. METHODS The present study analyzed data from the Korea National Cancer Screening Survey 2017, a nationally representative random sample of 4500 Korean individuals targeted for screening for the five most common types of cancer. A total of 1922 participants were included in the final analysis. The baseline characteristics of the study population are presented as unweighted numbers and weighted proportions. Both univariate and multivariate logistic regression models were developed to examine factors related with acceptance of an upper age limit for CRC screening; subgroup analysis was also applied. RESULTS About 80% (1554/1922) of the respondents agreed that CRC screening should not be offered for individuals older than 80 years. Specifically, those who had never been screened for CRC had the highest acceptance rate (91%). Overall, screening history for CRC [screened by both fecal occult blood test and colonoscopy, adjusted odds ratio (aOR) = 0.33, 95%CI: 0.22-0.50] and other cancers (aOR = 0.55, 95%CI: 0.34-0.87), as well as a family history of cancer (aOR = 0.66, 95%CI: 0.50-0.87), were negatively associated with acceptance of an upper age limit for CRC screening. In contrast, metropolitan residents (aOR = 1.86, 95%CI: 1.29-2.68) and people who exercised regularly (aOR = 1.42, 95%CI: 1.07-1.89) were more likely to accept an upper age limit. After subgrouping, we found gender, marital status, and lifetime smoking history among never-screened individuals and residential region, family history of cancer, and physical activity among never-screened individuals to be associated with acceptance of an upper age limit. CONCLUSION This study describes acceptance of an upper age limit for CRC screening and factors associated with it, and provides perspectives that should be considered, in addition to scientific evidence, when developing population-based cancer screening policies and programs.

Objetivo: Evaluar la adhesión terapéutica al TARGA de los pacientes reclusos con VIH y su relación con diferentes tipos de variables. Material y Método: Estudio longitudinal, realizado en el Centro Penitenciario de Hombres de Barcelona. Se utilizaron las bases de datos del centro, una entrevista semiestructurada, que valoraba variables sociodemográficas, penales/penitenciarias, clínicas y características del tratamiento, así como cuestionarios sobre creencias y estados emocionales. También se evaluó la adhesión al inicio del estudio, a los tres y a los seis meses. Resultados: Los internos presentaron un bajo apoyo social; un acuerdo medio respecto de los cuidados recibidos por el personal médico y sanitario; consideraron la complejidad del tratamiento como alta y concedieron una moderada relevancia a los efectos secundarios; presentaron un elevado acuerdo respecto a los beneficios que les podían reportar seguir el tratamiento, una percepción moderada sobre la severidad de la enfermedad y manifestaron una elevada autoeficacia en el seguimiento del tratamiento. Respecto a las variables emocionales mostraron una baja tensión, depresión, cólera y fatiga. La adhesión a los antirretrovirales desde el inicio al final del estudio no ha variado a lo largo del estudio. Las variables socio-cognitivas que correlacionaron con la adhesión en los diferentes momentos del estudio son la autoeficacia, los beneficios percibidos, la complejidad del tratamiento y los efectos secundarios. Los estados emocionales que correlacionaban con la adhesión eran la depresión y la fatiga. Discusión: La relación entre autoeficacia y adhesión es un resultado repetido en los estudios sobre la predicción de la adhesión al TARGA. Las relaciones de la fatiga y de la tristeza/depresión con la adhesión son del tipo esperado Objective: to assess therapeutic adherence to HAART amongst HIV positive inmates and its likely relationship with sets of different variables. Materials and Methods: longitudinal study carried out at the Men's Prison of Barcelona (Centro Penitenciario de Hombres de Barcelona). The prison data base, a semi-structured interview assessing socio-penal, demographic and clinical variables as well as treatment characteristics, and questionnaires on beliefs and emotional states were used. Adherence at the beginning of the study, and then after three and six months was also assessed. Results: inmates presented with low levels of social support, and showed moderate agreement regarding care received from medical and health personnel. They considered the level of treatment complexity to be high and gave moderate relevance to treatment side effects. They presented high agreement with the potential benefits of continuing with the treatment and showed moderate perception of the severity of the illness. They also showed high levels of self efficacy where treatment monitoring was concerned. The emotional variables showed low blood pressure, depression, anger and fatigue. Adherence to antiretroviral treatment did not vary throughout the study period. Socio-cognitive variables that correlated with adherence at different times of the study were self efficacy, perceived benefits, treatment complexity and side effects. Emotional states that correlated with adherence were depression and fatigue. Discussion: the relationship between self efficacy and adherence is frequently mentioned in studies on the prediction of HAART adherence. The relationship between the two factors of fatigue and sadness/depression and adherence was expected