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BACKGROUND: Sharing of knowledge and positive workplace behavior by employees are perquisites for the success of every organization. The present study realized the significance of knowledge sharing and positive behavior in a country like India where high-power distance culture is prevalent. OBJECTIVE: The present research aimed to investigate the influence of abusive supervision on knowledge hiding and employee organizational deviance. In addition mediating roles negative affectivity and employee silence were alsotested. METHODS: Data was gathered from 420 employees working in a service organization in India. SPSS vs. 23 and Amos vs. 24 were used for data analysis purposes. The techniques of SEM were applied to test the proposed hypotheses in the present research. RESULTS: The study found the positive and significant influence of abusive supervision on knowledge hiding, but the insignificant influence of abusive supervision on employee organizational deviance. The results also reflected the full mediating role of negative affectivity but the partial intervening or mediating role of employee silence between the relationships of abusive supervision with knowledge hiding and employees’ organizational deviance. CONCLUSION: The study suggested the management introduce various measures to reduce abusive supervision leading to negative consequences.

A novel organic acid-modified starch and carboxymethyl cellulose (CMC) based films plasticized with glycerol were prepared from unconventional tikhur starch (Curcuma angustifolia) by solution casting. Wet milling was used in the laboratory to extract starch from the tikhur rhizome. Carboxymethyl cellulose, at a concentration of (0.2 g−1 starch dry basis) was blended with the starch to improve its film-forming properties. Three different treatments with varying organic acids (lactic, citric, and acetic acid) with a concentration of 5% w/w of starch (2 ppm) in a film-forming solution were given. The effect of organic acid incorporation on the antibacterial, morphological, structural, thermal, and crystalline properties of developed films was studied. The minimum inhibitory concentration values of the three organic acids against gram-negative (E. coli) and gram-positive (S. aureus) bacteria were measured using the tube dilution method. The MIC results revealed that lactic acid and citric acid are effective against both gram-negative and gram-positive bacteria, while acetic acid showed more effectiveness against gram-negative bacteria (E. coli). MBC results revealed that organic acids have potent bactericidal activity. Citric acid resulted in higher inhibition for gram-positive bacteria (S. aureus) compared to gram-negative bacteria (E. coli.). While acetic acid showed higher inhibition for E. coli. than S. aureus. Lactic acid displayed similar inhibition against both S. aureus and E. coli. Among different organic acids, lactic acid incorporation resulted in a more homogeneous, transparent, and thermally stable film. As evidenced by the micrographs, the lactic acid incorporation resulted in a compact film structure without any visible cracks. While X-ray diffraction showed an increase in crystalline properties due to organic acid modification. In this study, it was indicated that modification with organic acids (polycarboxylic acids) effectively improved the overall properties of developed films depending on the type of organic acid used. The developed films have the potential to replace harmful synthetic films in food packaging.

BACKGROUND: Given the growing issues in environmental management, there is a need to respond to this increasing pressure by implementing the strategy of sustainability like green human resource management. OBJECTIVE: The study focuses on examining the influence of practicing green human resource management activities on environmental performance. The research also explores the interplay of Green HRM, green innovation, and service leadership in influencing environmental performance. METHODS: The technique of SEM analysis was applied to examine the direct and indirect effects. The data was captured from 328 employees of the Indian IT sector. RESULTS: The findings indicated the positive and significant mediating role of green innovation (product and process) between Green HRM and Environmental performance. Servant leadership also moderates their relationship thereby strengthening the positive influence of Green HRM on environmental performance. CONCLUSIONS: The large industries need to upgrade their system to GHRM for embedding green values, culture, and attitudes in the organization. Hiring the employees with environmental consciousness, training, and rewarding them for the promotion of an environmentally friendly culture promote green innovation. These practices with green innovation and servant leadership ensure that green initiatives are instilled in employees for the responsible behavior for positive environmental performance, which is a global need.

PurposeIn this paper, temperature distribution and fin efficiency in a moving porous fin have been discussed. The heat transfer equation is formulated by using Darcy's model. Heat transfer coefficient and thermal conductivity vary with temperature. The surface emissivity of the fin varies with temperature as well as with wavelength. Thermal conductivity is taken as a linear and quadratic form of temperature. The entire analysis of the paper is presented in non-dimensional form.Design/methodology/approachIn this study, a new mathematical model is investigated. The novelty of this model is surface emissivity which is considered temperature and wavelength dependent. Another interesting point is the addition of porous material. The Legendre wavelet collocation method has been used to solve the nonlinear heat transfer equation. Numerical simulations are carried out in MATLAB software.FindingsAn attempt has been made to discuss temperature distribution in the presence of porosity and wavelength-temperature-dependent surface emissivity. The effect of various parameters on temperature has been discussed, including thermal conductivity, emissivity, convection-radiation, Peclet number, sink temperature, exponent “n” and porosity. Fin efficiency is also calculated for some parameters. According to the study, heat transfer rate increases with higher radiation-convection, emissivity, wavelength and porosity parameters.Originality/valueThe numerical results are carried out by using the Legendre wavelet collocation method, which has been compared with exact results in a particular case and found to be in good agreement. The percent error is calculated to find the error between the current method and the exact result. A comparison of the obtained results with the previous data is presented to validate the numerical results.

Background: Varying types of malocclusions may have an effect on the morphology and position of the condyle in the glenoid fossa.Aim: This retrospective study aims to evaluate and compare the three-dimensional position and morphology of the condyle in the glenoid fossa in Angle’s Class I, Class II division I, Class II division II and Class III malocclusions using cone-beam computed tomography panoramic reconstructions.Material and Method: Pre-treatment CBCT scans of 40 subjects (17-30 years) with 10 subjects in each of the study groups as per Angle’s malocclusion were obtained. The CBCT images of all subjects were evaluated and compared following parameters, i.e., differences in anterior joint space, posterior joint space, superior joint space, anteroposterior and mediolateral width of the condyle, condylar height, and the vertical distance of the geometric center of the condyle from the mid-sagittal plane.Result: Statistical analysis revealed all parameters were statistically similar for all the malocclusion groups except the anterior and the superior joint space. The latter two parameters were significantly smaller in subjects with class III malocclusion compared to class I (p

Background: Improvements in dental health, function, beauty, and self-esteem are widely acknowledged advantages of orthodontic treatment. An economic evaluation of orthodontic treatment forms the basis for decision-making planning and management of dental care. Aim: This study aims to estimate the perception of patients seeking orthodontic treatment categorized according to age, education, and family income and to identify barriers that prevent them from considering treatment. Methodology: Proforma was sent to dental colleges and specific clinics from metro, urban and rural areas across India. 500 patients seeking orthodontic treatment took part in the survey. Data was collected and analyzed statistically. Results: Cost was the main factor, which patients felt was responsible for not completing treatment or preventing them to consider the treatment. All patients felt that a good smile should be included in the Right to Health by Government and steps should be taken to make this treatment accessible for all.

Introduction: Birth of a child is a special moment of joy for the parents but the first few minutes after birth are full of concern and rapid physiological adaptation. Most babies go through the transition successfully as a matter of routine, however, 10% of babies who do not start breathing immediately and need special care to initiate breathing. Aims & Objectives: The aim of the study was to assess the knowledge and practices among nursing students. The conceptual framework of the study was based on CIPP (context, input, process and product) model by Stufflebeam. Methodology & Theoretical Orientation: The research approach adopted for the study was quasi-experimental and design was non-equivalent control group pretest-posttest design. The study was at College and Institute of Nursing, Ambala, Haryana. A total of 64 BSc third year nursing students who were in the age group of 19-24 years selected by simple random technique and conveniently assigned into CT (n=32) and VAT (n=32) group. The tool used for the study consisted of structured performa regarding sample characteristics, structured questionnaire and structured observational checklist to assess the knowledge and practices of students. Data collection was done in January 2017. Descriptive and inferential statistics were used to analyze the data. Findings: The major findings revealed that within the groups the post test scores were significantly higher than the pre-test scores in both the groups whereas, in comparison, the mean post-test knowledge score of CT group (21.50±3.09) was nearly equal to the mean post-test score of VAT group (21.16±4.07) and mean post-test practice score of CT group (32.47±5.14) was slightly higher than the mean post-test score of VAT group (29.61±6.46) but computed ‘t’ value of mean post-test knowledge and practice score of both CT and VAT group (0.38, 1.90) were found to be statistically non-significant at 0.05 level of significance. Conclusion & Significance: Both CT and VAT were found to be equally effective in improving knowledge and practices of nursing students regarding neonatal ET intubation. So, VAT can be combined with CT to enhance better learning and skill development of nursing students. Keywords: Conventional Teaching, Video Assisted Teaching, Neonate, Endotracheal Intubation, Knowledge, Practice.

Antimicrobial resistance (AMR) is one of the leading global health issues that demand urgent attention. Very soon the world will have to bear the consequences of increased drug resistance if new anti-infectives are not pumped into the clinical pipeline in a short period. This presses on the need for novel chemical entities, and the marine environment is one such hotspot to look for. The Ocean harbours a variety of organisms, of which from this aspect, “Sponges (Phylum Porifera)” are of particular interest. To tackle the stresses faced due to their sessile and filter-feeding lifestyle, sponges produce various bioactive compounds, which can be tapped for human use. The sponges harbour several microorganisms of different types and in most cases; the microbial symbionts are the actual producers of the bioactive compounds. This review describes the alarming need for the development of new antimicrobials and how marine sponges can contribute to this. Selected antimicrobial compounds from the marine sponges and their associated bacteria have been described. Additionally, measures to tackle the supply problem have been covered, which is the primary obstacle in marine natural product drug discovery.

Background: Preoperative education is to not only prepare the child for their surgery, but also to reduce the risk of post-operative complications from occurring. Objectives: To Assess and compare the post operative outcomes of the children undergoing surgery after administration of predesigned instructions in comparison and experimental group, and to find out the association of post operative outcomes with selected variables in comparison and experimental group. Design: Quasi-Experimental research design “Non equivalent control group post test - only design was used. Participants: Data was collected from 30 caregivers of children undergoing surgery (15 in each group) by convenience sampling technique. Setting: Pediatric Surgical ward of Maharishi Markandeshwar Institute of Medical Sciences and Research Hospital, Mullana, Ambala, Haryana. Respiratory assessment scale & wound assessment scale were used to collect data. Result: The mean post operative respiratory score of children was comparatively less in the experimental group (day 1- 6.47±0.91 & day 4 - 6.40 ±0.63) as compared to the comparison group (day 1- 6.93±1.58 & day 4 - 6.47 ±0.74) and the mean wound status score in experimental group (day 3- 7.80±1.52) whereas in comparison group (day 3 - 8.20±2.21) was found to be non significant at 0.05 level of significance. Significant association of post operative respiratory status and wound status of children with selected demographic variables. Conclusion: Predesigned Instructions were effective for Caregivers of Children Undergoing Surgery in improving post operative outcomes of children and caregivers.

Mycobacterial pathogens including Non-tuberculous mycobacteria (NTM) and M. tuberculosis (Mtb), are pathogens of significant worldwide interest owing to inherent drug resistance to a wide variety of FDA-approved drugs as well as causing a broad range of serious infections. Identifying new antibiotics active against mycobacterial pathogens is an urgent unmet need, especially those antibiotics that can bypass existing resistance mechanisms. In this study, we demonstrate that Gepotidacin, a first-in-class triazaacenapthylene topoisomerase inhibitor, shows potent activity against Mtb and M. fortuitum as well as against other NTMs species, including fluoroquinolone-resistant M. abscessus. Furthermore, Gepotidacin exhibits concentration-dependent bactericidal activity against various mycobacterial pathogens, synergizes with several drugs utilized for their treatment, and reduces bacterial load in macrophages in the intracellular killing assay comparable to amikacin. Additionally, M. fortuitum ATCC 6841 was unable to generate resistance to Gepotidacin in vitro. When tested in a murine neutropenic M. fortuitum infection model, Gepotidacin caused a significant reduction in bacterial load in various organs at 10 fold lower concentration than amikacin. Taken together, Gepotidacin possesses a potentially new mechanism of action that enables it to escape existing resistance mechanisms. Thus, it can be projected as a potent novel lead for the treatment of mycobacterial infections, particularly for NTM, where present therapeutic interventions are very limited.

When dynamic nature, autonomous, self- configured types nodes are combined together and make contact with each other for the purpose of communication and data sharing; these types of forms networks are known as a mobile ad hoc network. The nodes don't restrict themselves due to physical barrier. They move into any location, place and communicate with the other nodes within their communication range. There is no fixed location of nodes. The dynamic nature of MANET makes it vulnerable to different type of attack. We are considering the wormhole attack which affects the network by transferring the data from one location to another location using a long range tunnel. In this paper, we are evaluating the performance of the proposed scheme with existing schemes such as RTT1, RTT2, DelPHI. The performance of the proposed scheme is measured in terms of throughput, packet delivery ratio, packet loss, average E2E delay and jitter.

A honey-pot is a type of toolkit used to deceive attackers, designed to detect an attacker attempting to compromise the production systems of any institute/organization. If designed and deployed correctly, a honeypot can act as an advance surveillance device and well as a threat intelligence gathering device. It is used to analyse the behavioural signature of the intruders trying to attack a system and to provide informational insights into potential system loop-holes.

Sustainability is the important issue for most of the organisation for reaping the benefit of triple bottom line and competitive advantage. Green human resource management is one of the ways to attain the sustainability which also helps in attracting and retaining the young talent towards the organisation. The purpose of the present research is to study the concept of Green HRM with various dimensions and to investigate the mostly researched domain related to Green HRM. The study discussed the key and major focus areas in the literature in the context of GHRM as per the author's view to accomplish the stated objectives. The results of the study showed the manufacturing domain has been focused by most of the studies due to the direct consumption of natural resources more in this sector. Further, originality or practicality of the research lies as this research would be helpful to the HR practitioners to focus only on key areas to implement the concept of GHRM well in their respective organizations to formulate the competitive strategy to add value to their respective organizations.

Image Enhancement is used as a preprocessing step in many computer vision applications. It provides enhanced input for other computerized image processing methods. Many preprocessing techniques can be applied to images depending on the application domain. In this paper we are proposing an image enhancement technique for color images that can be used as preprocessing step in many computer vision applications. It can also be used as a data augmentation technique in object detection. Luminance component of images is sometimes not captured by cameras and displayed by monitors properly. To remove this drawback of devices we have used gamma encoding. Four different values of gamma are evaluated depending on the quality of images. Image is then converted into YUV Color space. Y component represents the luminance. U and V components represent color. After that Contrast Limited Adaptive Histogram Equalization is applied to the Y component to improve the contrast of the image. The results are compared with the state-of-the-art methods on the basis of Peak Signal to noise Ratio (PSNR) and Mean Square Error (MSE). Quantitative results show that proposed algorithm results in improved value of PSNR and decreased value of MSE as compared to existing methods. Qualitative comparison is also done and results show improvement over the existing techniques.

Dentistry, in all its neoteric era revolves around the techniques and procedures that are advantageous and patient friendly. Such a research led to the institution of light amplification and stimulated emission of radiation technique, both in medicine and dentistry. Lasers are currently being followed in all the specialties including orthodontics, wherein it has dramatically decreased the treatment timings, resulting in better outcomes along with pain reduction procedures, greater patient satisfaction and a superior practice. Keywords: Light amplification and stimulated emission of radiation (LASER), Orthodontics, Dentistry, LLLT, Accelerated tooth movement, Crown lengthening, Micro-etching of enamel.

Electronic cigarettes also known as e-cigarettes, which deliver a vaporised smoke of nicotine and promise less toxicants than conventional cigarette smoke. However, studies suggest e-cigarettes are not completely harmless but are less dangerous than traditional cigarettes. The promise of help in smoking cessation effectiveness is still unproven and requires further evidence and studies. There are ongoing studies on deleterious oral and systemic health effects. Because of the rising popularity of vaping, it is absolutely vital that dental professionals must stay informed to provide patients truthful information as new data emerge. Keywords: Ecigarette, Vaping, Smoke, Cigarette, Oral health, Effect.

We proposed gas sensor based on a simple configuration of a quad-band metamaterial absorber (MMA), the unit cell of the proposed sensor is designed with three metallic rods placed inside a square metallic ring, on the top of a grounded dielectric substrate. The proposed sensor has a sensitivity 170GHz/RIU.

The Building’s material embodied energy plays major role in Carbon Emissions at its production stage. Assessment of Carbon emissions at initial stages for a high performance commercial building is overlooked and the building life cycle has not found an eminent place in the country mandatory norms. An early LCA can be instrumental in taking key decisions in design and material choice to lower building Carbon emissions. This paper aims at comprehensively evaluating and analyzing a fully glazed Certified high performance Office building in Gurgaon, Haryana. Process based Life Cycle Assessment of Building Envelope and Structure for Embodied energy and Carbon emissions is done by applying recently published Indian Database. The Building is modelled using Autodesk Revit Architecture for Bill of quantities extraction. Thereafter, LCA is done in tabular format as per Global standards for two cases, Base case with conventional material and As-built case with used material. Major reductions in emissions are due to Building Envelope material and not Structure. Concrete and Steel are major contributors. Fly Ash block and Gypsum plaster play major role in carbon emission reduction whereas double glazing, Aluminum and ACP contribute towards increasing emissions. Analysis done at early stages can be beneficial in exploring more design optimized techniques that are less Carbon intensive.

We 3D-print a nanofin-supported waveguide bridging two cores at the fiber tip and further coupled to a printed ring resonator. The resonance wavelength shift is probed from the fiber’s distal end, shifting by 47 pm/°K.

Klebsiella pneumoniae (K. pneumoniae) colonizes the human gut and is a causative factor of pyogenic liver abscess (PLA). Retrospective studies conducted on K. pneumoniae PLA patients revealed subsequent CRC development in later years of their life with increasing prevalence of these strains harbouring polyketide synthase (PKS) genes. To our knowledge there are no known studies directly implicating K. pneumoniae with CRC to date. Our aims are to characterize K. pneumoniae isolates from CRC patients and investigate its effects on cell proliferation in vitro. K. pneumoniae isolates were characterized by screening virulence genes including polyketide synthase (PKS), biofilm assay, antibiotic susceptibility, and string test to determine hypervirulent (hvKp) strains. Solubilised antigens of selected K. pneumoniae isolates were co-cultured with primary colon cell lines and CRC cell lines (Stage I-IV) for 48 h. The enhancement of proliferation was measured through MTT and ECIS assay. Twenty-five percent of K. pneumoniae isolates were PKS-positive out of which 50% were hvKp strains. The majority of the isolates were from the more virulent serotype of K1 (30%) and K2 (50%). PKS-positive K. pneumoniae isolates did not possess genes to confer carbapenem resistance but instead were more highly associated with siderophore genes (aerobactin, enterobactin, and yersiniabactin) and allantoin metabolism genes (allS, allS2). Cell proliferation in primary colon, SW1116 (Stage I), and SW480 (Stage II) CRC cell lines were enhanced when co-cultured with PKS-positive K. pneumoniae antigens. ECIS revealed enhanced cell proliferation upon recurrent antigen exposure. This demonstrates the possible role that PKS-positive K. pneumoniae has in exacerbating CRC progression.

Deep learning has been a game changer in the field of object detection in the last decade. But all the deep learning models for computer vision depend upon large amount of data for consistent results. For real life problems especially for medical imaging, availability of enough amounts of data is not always possible. Data augmentation is a collection of techniques that can be used to extend the dataset size and improve the quality of images in the dataset by a required amount. Logically it is used to make the deep learning model independent of the counterfeit features of the data space. In this paper a comprehensive review of data augmentation techniques for object detection is done. Problem of class imbalance is also outlined with possible solutions. In addition to train time augmentation techniques an overview of test time augmentations is also presented.

Proper diet and nutrition are important factors which influence the general health, growth and tissue tolerance of orthodontic patients on many levels.While orthodontist will rarely see frank manifestations of nutritional deficiencies, it should be recognized that suboptimal levels of certain nutrients are common and have an effect on the biological response of the tissues influenced by orthodontic treatment. Orthodontic treatment involves the use of attachments and forces element that can negatively affect the dietary intake compromising the nutrition of the patient. On the other hand for effective orthodontic treatment a balanced diet is required. Thus it becomes a vicious cycle. Most orthodontic patients are in the growing age. Balanced diet is essential for them. However some food in its hard and crunchy form may be avoidable during orthodontic treatment. Therefore alternate methods of intake of such food item is essential. This article highlights the importance of dietary considerations for orthodontic treatment and also how the patient can alter their dietary habits without compromising on nutrition. Keywords: Diet, Food, Orthodontic patients, Nutrition, Fruits.

C-reactive protein (CRP) is an acute-phase protein belongs to pentraxins family with a feature of ve identical globular subunits. Two different isoforms i.e. pentameric CRP (pCRP) and monomeric CRP (mCRP) have different key role in regulation. The key biological function of CRP is host defense using classical complement pathway against bacterial infection and involved in removal of apoptotic and necrotic cells. Although CRP is mainly associated with inammation in bacterial infection such as tuberculosis or Pneumococcus infection, however it is also presence in atherosclerosis, cardiovascular disease (CVD) and in various cancers which make it good candidate for prognostic study in different clinical conditions.

The identification of a fuzzy model is a complex and nonlinear problem. This can be formulated as a search and optimisation problem and many computing approaches are available in the literature to solve this problem. This research paper is focused on using a new nature inspired approach for fuzzy modeling based on Bat Algorithm which is derived from the behaviour of micro-bats to search for their prey. The bat algorithm approach has been implemented and validated successfully on a rapid battery charger fuzzy controller problem. Currently, the key requirement is real-time solutions to complex problems at a blazing speed. Bat algorithm evolved the optimised fuzzy model within a few seconds as compared to other approaches.

Background: Neonatal period, the first 28 days of life is most vulnerable and crucial time for babies, whose birth weight is less than 2.5 kg. Developmental supportive care is an integrated approach for these babies. The main objectives of the study were to assess and compare neonatal outcomes (physiological, comfort behavior) of LBW Babies before and after implementation of Developmental Supportive Care Bundle in experimental and comparison group and to determine the association of neonatal outcomes of LBW Babies with their selected demographic variables in experimental and comparison group. Methodology: Quasi-Experimental research design (Non- Equivalent Control Group Pretest Posttest Design) was used. Data was collected from 30 Low Birth Weight Babies (15 in each group) by convenience sampling technique in NICU of MMIMS&R of Ambala, Haryana. Pre assessment – temperature and pain assessment done before intervention in both group. After that intervention given in only experimental group and post test done on 2 to 5 days. On day 4, the mean post implementation score (36.60) of temperature was found significantly (p=.01*) higher in experimental group. On day 2 to 5, the mean post implementation score (6.80, 6.40, 6.47 and 6.47) of comfort behavior was found to be significantly (p=.006*, .001*, .005* and .002* respectively) higher in experimental group. Conclusions: The findings of the study concluded that Developmental Supportive Care Bundle (DSCB) was effective in improving neonatal outcomes (temperature and comfort behavior) of Low Birth Weight babies.

Tuberculosis (TB) is a potentially fatal contagious disease and is a second leading infectious cause of death in the world. Osteoarticular TB is treated using standard regimen of 1st and 2nd line anti-tubercular drugs (ATDs) for extensive period of 8-20 months. These drugs are commonly administered in high doses by oral route or by intravenous route, because of their compromised bioavailability. The common drawbacks associated with conventional therapy are poor patient compliance due to long treatment period, frequent and high dosing, and toxicity. This aspect marks for the need of formulations to eliminate these drawbacks. MTB is an intracellular pathogen of mononuclear phagocyte. This attribute makes nanotherapeutics an ideal approach for MTB treatment as macrophages capture nano forms. Polymeric nanoparticles are removed from the body by opsonization and phagocytosis, which forms an ideal strategy to target macrophage containing mycobacteria. To further improve targetability, the nanoparticles are conjugated with ligand, which serves as an easy substrate for the receptors present on the macrophage surface. The purpose of present work was to develop intra-articular injectable in situ gelling system containing polymeric nanoparticles, which would have promising advantages over conventional method of treatment. The rationale behind formulating nanoparticle incorporated in situ gel-based system was to ensure localization of the formulation in intra-articular cavity along with sustained release and conjugation of nanoparticles with mannose as ligand to improve uptake by macrophages. Rifampicin standard ATD was formulated into chitosan nanoparticles. Chitosan with 85% degree of deacetylation (DDA) and sodium tripolyphosphate (TPP) as the crosslinking agent was used for preparing nanoparticles. The percent entrapment was found to be about 71%. The prepared nanoparticles were conjugated with mannose. Conjugation of ligand was ascertained by performing Fourier transformed infrared spectroscopy. The particle size was found to be in the range of 130-140 nm and zeta potential of 38.5 mV. Additionally, we performed scanning electron microscopy to characterize the surface morphology of ligand-conjugated nanoparticles. The conjugated chitosan nanoparticles were incorporated into in situ gelling system comprising Poloxamer 407 and HPMC K4M. The gelling system was evaluated for viscosity, gelling characteristics, and syringeability. The drug release from conjugated nanoparticles incorporated in in situ gel was found to be about 70.3% at the end of 40 h in simulated synovial fluid following zero-order release kinetics. Based on the initial encouraging results obtained, the nanoparticles are being envisaged for ex vivo cellular uptake study using TB-infected macrophages.

Background: The pandemic of COVID-19 has been spreading around the world very rapidly and has took aterrible shape. The one of the better ways to deal with this terrible pandemic is to have thorough knowledgeabout it and act consequently.Objectives: The present study aim at assessing and comparing the knowledge of Students about COVID 19and its hasty expansion.Material and Methods: Descriptive cross-sectional research design was adopted for the study. Data usingonline structured knowledge questionnaire was collected from 316 participants which was selected usingconvenient sampling technique from selected University of Ambala. The data was collected from studentsof Nursing, Physiotherapy and IT department.Results: The mean age of participants among Nursing was 21.75 + 1.77, 23.43 + 2.62 among physiotherapywhereas 23.22+ 2.28 among IT department. In relations to Gender it was found that most (76 %) of theparticipants were female and only 24 percent were male among Nursing, 66 percent’s participants werefemale, and 34 percent were male among physiotherapy while 56 percent were female and 44 percentwere male in the IT department. 47 percent participants from the Nursing, 40 percent participants fromphysiotherapy and 20 percent participants form IT were having good knowledge. The knowledge scoreamong Nursing Participants ranged from 17 to 46, 15 to 47 among Physiotherapy whereas it was 17 to 47among IT participants. The mean knowledge score of the Nursing participants was 33.84 + 5. 48, 32.91+6.67among physiotherapy and it was 31.63+5.98 among IT. Repeated measure ANOVA was calculated whichshows a statically significant difference (F=1.07, p=0.00) among three groupsConclusion: The study concluded that continuing teaching experience is required to the students regardingpreventive measures as well as change in the treatment regimen

The current novel coronavirus and the disease it causes, Covid-19 is one of the most unpredictable global public health crises in recent times. The pandemic situation worldwide has made everyone to take unprecedented roles in intensifying online learning and upgrading educational strategies to make students aware of this disease. The objective of the present study was to assess and compare the effectiveness of virtual learning program on the knowledge of Students regarding Covid-19 amid its rapid upsurges. Quantitative Approach with Quasi-experimental (One group pre-test post-test design) was used. Convenient sampling technique was used to collect the sample size of 370 participants from selected colleges of Ambala, Haryana. The data was collected through the Structured Knowledge Questionnaire using Google forms. The Questionnaire comprised of 35 items covering different domains of COVID-19. Pre-test was conducted to assess the prior knowledge of students regarding COVID-19. Virtual learning (synchronous) was conducted on Day 2, using Google classroom. The post-test was conducted on Day-10 using same tool to assess the effectiveness of Virtual learning. The mean post-test knowledge score 24.02 was higher than mean pre-test knowledge score, i.e., 20.87 with a mean difference of 3.15. The t-value of 1.64 (p. 0.04) shows a statistically significant difference in the knowledge scores of the students before and after implementation of Virtual learning on COVID-19. There was a significant association (7.01, p-value 0.05) found between gender and level of knowledge. The study concluded that the virtual learning was effective in improving the knowledge of students regarding COVID-19.

During the period of COVID-19 Lock-down the e-learning became very popular by dependency of both teachers as well as the learners to avoid interruptions in their academic progress In a view to assess the effectiveness and evaluate the adaptation of the students towards e-learning, a survey was conducted among the nursing students in the form of feedback The feedback was mainly focused on the student’s interest, and the efforts taken by teachers in regard to class time and pace, organization and preparations of class, and fair assessment opportunities provided by teachers etc The survey results were computed through Microsoft excel analysis based on the central tendencies, reveals that the Most of students “Agree”, maximum have “Strongly Agree” and very few students have “Disagree” to the approaches and efforts of the teachers taken during e-learning It was concluded from study that majority of the students had strongly agree that faculty organized and prepared well for every class and faculty were encouraged in discussions and responded to questions © 2020, Institute of Medico-Legal Publications All rights reserved

When it comes to computer vision, the most challenging and crucial field is Face recognition with latest technology system. There are plenty of research articles available, and had done lot of research in this domain to achieve the stability, but due to the timely Changes new challenges has been occurred with time and the research started towards to resolve the problem. As we have analyzed due to the certain changes of time and structure of face has reshaped with the effect of aging. So, various authors has discussed the face recognition without aging affect in plenty of articles, but all have some problems and low accuracy to identify the face. This research also describes face recognition with different face features like structure, shape, texture, size and many more. In this paper, we mainly considers two domains, face recognition and Age Invariant. The aim of this research is to include the face recognition work which does not achieved by previous researchers that does not discussed the significant methods, such as: Feature based, Appearance based and soft computing based method. To evaluate our technique, we used a large dataset known as Cross-Age Celebrity Dataset (CACD). This dataset contains more than 2000 Celebrities having 160,000 Images with age ranging from 16 to 62. We have used 1000 Images as input dataset for training and model evaluation. We proposed the Auto-encoder denoising deep neural Network, which extracts the 1000 features from image, and achieved 99.8% Accuracy.

Steroid cell tumours of the ovary are uncommon sex-hormone-secreting tumours characterized by steroid cell proliferation. The incidence of steroid cell tumour of the ovary is only 0.5% of all ovarian tumours. Here, we present a case of a 59-year-old post-hysterectomy patient who presented with complaints of excessive hair growth, hoarseness of voice and male pattern baldness for 1 year. Transvaginal ultrasonography revealed a well-defined solid 4 × 3 cm hypoechoic lesion, and there was increased heterogeneous vascularity on colour doppler suggestive of neoplastic solid mass lesion of the right ovary. A blood examination showed total serum testosterone of 76 ng/dL, DHEAS—310 ug/dL, and 17-OH progesterone—1025 ng/dL. Her haemoglobin in the preoperative period was 18 gm/dL, though erythropoietin levels were normal. The patient was found positive for JAK2 gene mutation, which is strongly associated with polycythaemia vera. Laparotomy followed by bilateral salpingo-oophorectomy and frozen section was planned. Since frozen section was positive for malignancy in right ovarian mass, omentectomy, bilateral pelvic and para-aortic lymphadenectomy with multiple peritoneal biopsies were performed. The result of histopathology confirmed the diagnosis of steroid cell tumour, probably Leydig cell tumour. A blood examination after a month revealed a marked decline in serum testosterone, i.e. 4.9 ng/dL, DHEAS—15.3 ug/dL, and 17-OH progesterone—0.13 ng/dL.

Single-mode polymer optical waveguides with air cladding, supported only by a narrow fin, were designed and fabricated by direct laser writing technique. The waveguides offer low bending losses and high confinement with increasing core diameter.

The present study aims to investigate the relationship between varying dimensions of self-regulation and the two components of metacognition. Metacognition and self-regulation should be explored as a serious issue in the educational context as both aim at helping learners to think about their own learning more explicitly. The sample for this study comprised 400 adolescents studying in class +1 and +2, exclusively drawn from the Government Senior Secondary Schools of rural and urban areas of Ludhiana and Moga districts of Punjab. The subjects were randomly selected and equally distributed over gender (males=200 and females=200) and locale (urban=200 and rural =200). Metacognitive Awareness Inventory (Schraw and Dennison, 1994) and Self-Regulation Questionnaire (Brown et al., 1999) were used to assessthe metacognition and self-regulation of adolescents, respectively. Irrespective of gender and locale, the results of Pearson Correlation analysis revealed a significant positive correlation between overall self-regulation and the components of metacognition (Knowledge about Cognition and Regulation of Cognition) as well as overall metacognition. Similar results were also observed in case of female respondents as well as the rural respondents, where a significant positive correlation was found between self-regulation and metacognition.

The 2016 Global Burden of Disease report by WHO revealed that diseases of the gastrointestinal tract (GIT) had one of the highest incidence rates worldwide. The plethora of factors that contribute to the development of GIT-related illnesses can be divided into genetic, environmental and lifestyle factors. Apart from that, the role that infectious agents play in the development of GIT diseases has piqued the interest of researchers worldwide. The human gut harbors approximately 1014 bacteria in it with increasing concentration toward the lower GIT. Among the various microbiota that colonize the human gut, Gram-negative bacteria have been most notoriously linked to GIT-related diseases such as inflammatory bowel disease (IBD) including Crohn's disease and ulcerative colitis and colorectal cancer (CRC). Some of the notable culprits that have been attributed to these diseases are Bacteroides fragilis, Fusobacterium nucleatum, Escherichia coli and Helicobacter pylori. However, studies in recent years are beginning to recognize a new player, Klebsiella pneumoniae (K. pneumoniae) in the causation and progression of GIT diseases. Once synonymous with infections and diseases of the upper respiratory tract, K. pneumoniae has now emerged as one of the pathogens commonly isolated from patients with GIT diseases. However, extensive studies attributing K. pneumoniae to GIT diseases, particularly that of CRC are scanty. Therefore, this review intends to shed light on the association of K. pneumoniae in gastrointestinal diseases such as Crohn's disease, ulcerative colitis as well as CRC.

We present a novel design of an optical switch based on grating-assisted non-linear directional coupler (GANDC) which consists of two non-identical waveguides, with a periodic refractive index perturbation in between the waveguides, along the direction of propagation. The proposed design of the optical switch reduces the critical power by a factor ~25, as compared to the conventional non-linear directional coupler-based switch, with potential applications in photonics.

Wastewater flowing in streams and nallahs across India carries several trace metals, including metalloid arsenic (As), which are considered serious environmental contaminants due to their toxicity, and recalcitrant nature. In this study, we determined the phytoremediation of As by Eichhornia crassipes (Mart.) Solms either alone or in association with plant growth-promoting rhizobacteria. Pseudomonas and Azotobacter inoculation to E. crassipes resulted in enhanced As removal compared to uninoculated control. Co-inoculation with a consortium of Pseudomonas, Azotobacter, Azospirillum, Actinomyces, and Bacillus resulted in a higher As (p < 0.05) phytoaccumulation efficiency. P. aeruginosa strain jogii was found particularly effective in augmenting As removal by E. crassipes. Our findings indicate that the synergistic association of E. crassipes and various rhizobacteria is an effective strategy to enhance removal of As and thus may be utilized as an efficient biological alternative for the removal of this metalloid from wastewaters.

The glasses of series xTiO2-xCeO2-(30-x) PbO-(70-x) B2O3 where 2 ≤x ≤ 10 mol% were made using conventional melt-quench method and X-ray diffraction technique has been used to ascertain the amorphous nature of these glasses. The analysis of the compositional dependence of the physical parameters like density, molar volume and oxygen packing density along with the elastic parameters (Young's modulus, shear modulus, Vickers hardness number) of the studied glasses has been done. Infrared (IR) spectra revealed BO3 and BO4 units as main glass forming groups in these glasses but at higher concentrations of TiO2, Ti3+ and Ti4+ ions get significantly incorporated in glass matrix thereby creating TiO4 and TiO6 structural units. Optical spectral studies indicated that the band gap energy values decreased with increasing TiO2 content and these glasses had good UV-blocking efficiency which could be exploited for their use as transparent UV shielding materials. The radiation shielding parameters such as Half Value Layer, Linear Attenuation Coefficient, Exposure Buildup Factor, Mean Free Path including thermal and fast neutron cross section were deduced which indicated that the attenuation performance of these glasses improved with the addition of TiO2. Lower values of Exposure Buildup Factor and higher values of thermal and fast neutron removal cross section reflect the proficient shielding ability of these glasses.

FNDR-20081 [4-{4-[5-(4-Isopropyl-phenyl)- [1,2,4]oxadiazol-3-ylmethyl]-piperazin-1-yl}-7-pyridin-3-yl-quinoline] is a novel, first in class anti-tubercular pre-clinical candidate against sensitive and drug-resistant Mycobacterium tuberculosis (Mtb). In-vitro combination studies of FNDR-20081 with first- and second-line drugs exhibited no antagonism, suggesting its compatibility for developing new combination-regimens. FNDR-20081, which is non-toxic with no CYP3A4 liability, demonstrated exposure-dependent killing of replicating-Mtb, as well as the non-replicating-Mtb, and efficacy in a mouse model of infection. Whole genome sequencing (WGS) of FNDR-20081 resistant mutants revealed the identification of pleotropic targets: marR (Rv0678), a regulator of MmpL5, a transporter/efflux pump mechanism for drug resistance; and Rv3683, a putative metalloprotease potentially involved in peptidoglycan biosynthesis. In summary, FNDR-20081 is a promising first in class compound with the potential to form a new combination regimen for MDR-TB treatment.