Chen, Jin, Li, Zihua, Zhang, Yudian, Zhang, Xu, Zhang, Shujie, Liu, Zonghan, Yuan, Huimei, Pang, Xiangsheng, Liu, Yaxuan, Tao, Wuchen, Chen, Xiaoping, Zhang, Peng, and Chen, Guo-Qiang
Additional file 1: Fig. S1. Protein expression of the protein homeostasis signaling pathway by western blot in soleus muscles of the hindlimb unloading model mice, fully uncropped and unprocessed images for Fbx32 (MAFbx), GAPDH, LC3B and GAPDH blot are listed. Fig. S2. Shows the definition of "3HB-regulated genes" (related to Fig. 3). Fig. S3. Shows principal component analysis (PCA) of whole transcriptome data and KEGG pathway of “3HB-regulated genes”, the transcript abundance changes of selected genes (in FPKM) and the results of real-time PCR analysis for Atg9, Vps13d, and Chac1 are also listed. Fig. S4. Shows protein expression of the Akt/FoxO3a and mTOR/4E-BP1 pathways by western blot in soleus muscles of the hindlimb unloading model mice, fully uncropped and unprocessed images for each blot are listed. Fig. S5. Shows relative abundance changes of glycine, neurotransmitters and metabolites of glycolysis and TCA cycle. Fig. S6. Shows the blood glucose and blood ketones in the HU model mice.