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The flash glucose monitoring (FGM) system FreeStyle Libre is a device that measures interstitial glucose in a very simple way and indicates direction and speed of glucose change. This allows persons with diabetes to prevent hypoglycemic and hyperglycemic events. Scientific evidence indicates that the system can improve glycemic control and quality of life. To obtain the maximum benefit, it is necessary to properly handle glucose values and trends. Due to the generalization of the system use, the purpose of the document is to provide recommendations for the optimal use of the device, not only in the management of glucose values and trends but also in the prevention of hypoglycemia, actuation in exercise, special situations, and retrospective analysis of the glucose data, among others.

Se ha desarrollado un algoritrr)o de programación matemática para el dimensionamiento óptimo de estructuras articuladas isostáticas. El algoritmo propuesto se caracteriza por: a) No requerir que la función objetivo o las ecuaciones de restricción sean derivables. b) Utilizan métodos de optimización unidimensionales para pasar de una solución dada a otra mejor, c) Introducir procedimientos aleatorios para obtener información que conduce a una solución mejor. Estas características lo hacen especialmente indicado para funciones no explícitas, costosas en su evaluación y con gran cantidad de mínimos relativos. Se ilustra el método con dos ejemplos de diseño óptimo de estructuras articuladas estáticamente determinadas An algorithm of mathematical programmation for the optimum dis'fgn of iso-static articúlate structures has been developed. The characteristics of the proposed algorithm are: a) It not requires that the objective function or the restriction equations be derivable. b) They use unidimensional methods of unidimensional optimization ío pass over from a g/Ven so/ut/on to a better one. c) To introduce contingent procedures to obtain Information which leads to a better solution. Those characteristics make it specially recommended for non-explicit functions, costly in its evaluation with a great deal of relative mínimums. The method is explained by two exampies of óptima! design of statiscally determined articulated structures