1. Spectrum of Frontotemporal Lobar Degeneration on 18F-FDG PET/CT Scan
- Author
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Ethel Shangne Belho, Harsh Mahajan, Vanshika Gupta, Ritu Verma, Rajeev Kumar Ranjan, and Nikhil Seniaray
- Subjects
Male ,Pathology ,medicine.medical_specialty ,Degenerative Disorder ,Degeneration (medical) ,Motor symptoms ,030218 nuclear medicine & medical imaging ,Progressive supranuclear palsy ,Primary progressive aphasia ,03 medical and health sciences ,0302 clinical medicine ,Fluorodeoxyglucose F18 ,Positron Emission Tomography Computed Tomography ,mental disorders ,medicine ,Humans ,Radiology, Nuclear Medicine and imaging ,business.industry ,General Medicine ,Frontotemporal lobar degeneration ,Middle Aged ,respiratory system ,medicine.disease ,nervous system diseases ,Gliosis ,030220 oncology & carcinogenesis ,Female ,Fdg pet ct ,Frontotemporal Lobar Degeneration ,medicine.symptom ,business - Abstract
FTLD (Frontotemporal lobar degeneration) is a clinically and pathologically heterogeneous group of degenerative disorders, characterized by predominantly asymmetric degeneration of frontal and temporal lobes with selective neuronal loss and gliosis. The disease presents with variable degrees of impairment in behavior, language, executive control, and motor symptoms with progressive loss of cognition. On the basis of presenting clinical symptoms, FTLD is further divided into behavioral variant, nonfluent/agrammatic variant primary progressive aphasia (PPA), semantic variant PPA, logopenic variant PPA, progressive supranuclear palsy, and corticobasal ganglionic degeneration. Here we illustrate the utility of FDG PET with statistical parametric analysis for evaluation of these patients.
- Published
- 2020