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With the development of deep learning and the progress of natural language processing technology, as well as the continuous disclosure of judicial data such as judicial documents, legal intelligence has gradually become a research hot spot. The crime classification task is an important branch of text classification, which can help people related to the law to improve their work efficiency. However, in the actual research, the sample data is small and the distribution of crime categories is not balanced. To solve these two problems, BERT was used as the encoder to solve the problem of small data volume, and attribute extraction network was added to solve the problem of unbalanced distribution. Finally, the accuracy of 90.35% on small sample data set could be achieved, and F1 value was 67.62, which was close to the best model performance under sufficient data. Finally, a text enhancement method based on back-translation technology is proposed. Different models are used to conduct experiments. Finally, it is found that LSTM model is improved to some extent, but BERT is not improved to some extent.

Additional file 1.

Additional file 1. SPIRIT 2013 Checklist: Recommended items to address in a clinical trial protocol and related documents.

In this paper, the spacecraft close-range safe proximity problem is investigated. In the presence of a “chief” spacecraft, a Multi-Equal-Collision-Probability-Curve (MECPC) method is developed. The influence of the chief spacecraft with a convex polygon shape is considered and the chief spacecraft is divided into several small components. Each component generates a corresponding separate repulsive force and the superposition of these forces is regarded as the ultimate avoidance force. As a result, the proposed MECPC method not only improves the system robustness against control and navigation uncertainties but is also analytically validated in collision avoidance. The MECPC method solves the safe proximity problem in the presence of a convex polygon shape. In addition, an Improved Linear Quadratic Regulator (ILQR) is designed to track the expected trajectory. Numerical simulations are performed in a close-range operation environment to verify the effectiveness of the proposed MECPC method.

Additional file 1. SPIRIT 2013 Checklist: Recommended items to address in a clinical trial protocol and related documents.

The three death cases of falciparum malaria in Wenzhou City were all imported from Africa. One patient died on 10 January 2007 because of severe clinical symptoms after hospitalization. The second case was initially misdiagnosed as influenza in primary health and medical institution. The patient's condition quickly worsened and died of Plasmodium falciparum infection on 5 March 2011. The third patient belonged to "non-identity" person, and there were no detailed information and epidemiological history on admission, which resulted in the delayed diagnosis, disease exacerbation and death. In conclusion, the health education should be provided to the people who return from Africa and also to medical workers in order to reduce the mortality of falciparum malaria.

To analyze the characteristics of malaria prevalence in Wenzhou City, so as to provide the evidence for improving the comprehensive control of malaria.The epidemiological data of malaria cases in Wenzhou City in 2015 were collected and analyzed with the descriptive epidemiological methods.Totally 24 imported malaria cases were reported in Wenzhou City in 2015 with the incidence of 0.26 per 100 000 and no case was dead.Malaria epidemic situation in Wenzhou City is relatively stable and no local malaria cases were reported in 2015. However, the control work of imported malaria should be strengthened.

The rapidly increasing use of engineered nanoparticles (NPs) in consumer products inevitably leads to their greater presence in wastewater treatment plants. In this study, the effects of zinc oxide nanoparticles (ZnO-NPs) on system performance and bacterial community dynamics of biological wastewater treatment in a lab-scale sequencing batch reactor were evaluated, along with their fate within the system. It was found that ZnO-NPs caused poor settleability of the activated sludge and a significant decrease in the removal of nitrogen and phosphorus over time. Denaturing gradient gel electrophoresis analysis revealed that the bacterial community in the activated sludge became less diverse after exposure to ZnO-NPs. In addition, the production of extracellular polymeric substances (EPS) increased, with the EPS forming a tight matrix to protect the cells from the NPs. The NPs were removed very effectively from wastewater, mainly via sorption to the sludge.

SPIRIT 2013. (DOC 124 kb)

Objective To study the effect of Shengmai San ( Pulse-activating Powder) in protecting myocardium in the rat of the type 2 diabetic cardiomyopathy (DCM) model. Methods The DCM rat model was established by combination of insulin resistance induced by a high-fat diet with intraperitoneal injection of high dose streptozotocin (50 mg/kg). And these rat models were randomly divided into three groups: a normal group ( n =12, one of them died), a model group ( n =15) and a Shengmai San group (treatment group, n =15). The damage of the myocardium was assessed by electrocardiogram at the twelfth week after modeling, and the blood glucose, cholesterol and triglyceride levels were determined; the content of the left cardiac ventricle myocardial collagen was quantified by Masson staining test; the level of myocardial cell apoptosis was detected with TUNEL apoptosis detection kit; the damage extent of the myocardial sub-cellular structures was observed by electron microscopy; the expression levels of cardiac TSP-1 (Thrombospondin-1), TGF-β1 (Transforming Growth Ffactor-β) and TRB-3 (Tribbles homolog 3) proteins were detected by immunohistochemical method; the expression levels of cardiac TSP-1, A-TGF-β1 and L-TGF-β1 proteins were detected by Western blotting; and the expression levels of TSP-1 and TRB-3 mRNAs were detected by real-time quantitative PCR. Results Compared with the control group, the blood glucose, cholesterol, triglycerides levels in both the model groups and the Shengmai San group were significantly decreased; the myocardial tissue was less damaged and the collagen content was reduced in the Shengmai San group; the myocardial sub-cellular structure was injured to a lesser extent; the expression levels of myocardial TSP-1, TGF-β1, TRB-3, and TSP-1, A-TGF-β1, L-TGF-β1 and chymase were decreased, and the expression levels of TSP-1 mRNA and TRB-3 mRNA were decreased in both the model groups and the Shengmai San group (the latter was better),. Conclusion Shengmai San can inhibit myocardial fibrosis in the rat of diabetic cardiomyopathy, and significantly delay the formation of diabetic cardiomyopathy in hyperglycemia rats through multiple pathways.

Uncoupling proteins (UCPs) are a proton transporter family located in the mitochondrial inner membrane. Thus far, five molecules (UCP1-UCP5) have been identified as members of the UCP family. Recently, UCPs have attracted considerable interest in research on energy metabolism and obesity. However, to date, no study has focused on a comprehensive and systematic evaluation of the tissue-specific distribution of UCPs in obese individuals. Our study presents evidence of differential tissue expression profiles of five isoforms of UCPs in normal and diet-induced obese (DIO) rats using real-time polymerase chain reaction (PCR) analysis. The results clearly show that the tissue-specific expression patterns of individual isoforms between DIO and normal rats are quite distinct, which suggests a close relationship between the alterations in UCP expression and dietary obesity.

A multi-character recognition method based on hidden Markov model (HMM) was presented. The method can reduce the calculation load of correlation and improve recognition accuracy compared with single-character recognition in video. The characteristics used for recognizing include the shape character, the color character, the texture character and so on. Even our human being generally uses these characteristics to recognize objects in practice. A recognition experiment of 17 fishes was carried out in the paper. The experimental results demonstrate the high veracity of the multi-character recognition algorithm. Together with the tracking process, it can handle dynamic objects, so the multi-character recognition is more like the human recognition, and has great application value.

Based on 2501 clinical cases of type 2 diabetes, the pathogenesis of type 2 diabetes was studied using the latent structural model, and the symptoms–pathogenesis relationship was established. The results show that the latent structure model, which is nonlinear, may serve as a good tool for investigating the nonlinear and complex traditional Chinese medicine symptoms.

We develop an approach to homogenize three-dimensional periodic solid–solid elastic composites with cubic lattice at low frequencies, by using plane wave expansion and perturbation theory with respect to the long wavelength limit. Based on the fact that the two shear waves propagating along lattice axis are degenerated, we derive formulae for effective velocities parallel and normal to the lattice axis, from which three independent effective elastic moduli are calculated, respectively. Theoretical results, which take into account the multiple scattering and the structure of the periodic medium, are in good agreement with the previous isotropic theory at high-symmetry directions.

Effective velocities of elastic waves propagating in two-dimensional phononic crystal at low frequencies are analysed theoretically, and exact analytical formulas for effective velocities of elastic waves are derived according to the method presented by Krokhin et al. [Phys. Rev. Lett. 91 (2003) 264302]. Numerical calculations for phononic crystals consisted of array of Pb cylinders embedded in epoxy show that the composites have distinct anisotropy at low filling fraction. The anisotropy increases as the filling fraction increases, while as the filling fraction closes to the limitation, the anisotropy decreases.

Adaptive evolutions to high-altitude adaptation have been intensively studied in mammals. However, considering the additional vertebrate groups, new perception regarding selection challenged by high-altitude stress on mitochondrial genome can be gained. To test this hypothesis, we compiled and analyzed the mitochondrial genomes of 5 alpine pheasants and 12 low-altitude species in Phasianidae. The results that evolutionary rates of ATP6 and ND6 showing significant fluctuation among branches when involved with five alpine pheasants revealed both genes might have implications with adapting to highland environment. The radical physico-chemical property changes identified by the modified MM01 model, including composition (C) and equilibrium constant (ionization of COOH) (Pk′) in ATP6 and beta-structure tendencies (Pβ), Pk′, and long-range non-bonded energy (El) in ND6, suggested that minor overall adjustments in size, protein conformation and relative orientation of reaction interfaces have been optimized to provide the ideal environments for electron transfer, proton translocation and generation of adenosine triphosphate (ATP). Additionally, three unique substitution sites were identified under selection in ND6, which could be potentially important adaptive changes contributing to cellular energy production. Our findings suggested that adaptive evolution may occur in alpine pheasants, which are an important complement to the knowledge of genetic mechanisms against the high-altitude environment in non-mammal animals.

The development of the Internet is a process from closed door to opening-up, and has been experiencing the stages of access first, content-based, application-oriented to service-oriented. This paper first expounded the development of the Internet open platform, then analyzed the value of the B to C shopping website open platform, and finally discusses the associate strategy with merchants of the B to C shopping website after opening its platform.

In this paper, we interpret the fundamental geometric invariants in a new framework: geometric algebra (GA). The study of such geometric invariance is a field of active research. The homogeneous model (Grassmann model) is selected for different kinds of geometric invariants, including Euclidean invariants, Projective invariants etc. GA focuses on the subspace of a vector space as elements of computation. Linear transformation can be extended to the subspace structure. The paper compares the meaning of invariants using the new model with that using the traditional one. This work shows that geometric algebra is a very elegant language for expressing geometric objects.

With the rapid development of Chinese e-commerce, comparison-shopping services have drawn wide attention and come into use in an all-round way. From the perspective of comparison-shopping services, this article discussed the rise and development of comparison-shopping search engines. It presented several constructive proposals on technical strategy and service innovation based on the analysis of the present situation in China, which might provide reference for the improvement of the quality of China's comparison-shopping services.

The quantitative relationships between the parameters of fracture mechanics and acoustic emission (AE) are investigated using two typical carbon fiber reinforced thermosoftening plastics (CFRTP) with evident differences in AE characteristics when undergoing monotonous tensile deformation. It is shown that the relation between cumulative AE events and the stress intensity factor does not hold well for the experimental results. The reason for this is that there exists a wide distribution of AE signal levels in composites. Therefore, a formula for the cumulative AE energy E and the stress intensity factor K is proposed as E = CK m . This gives a good result for the experiments in tensile deformation. Since the AE signal attenuation affects the cumulative AE energy, it is discussed for the proposed formula. It is found that the attenuation of AE signals has an influence on the coefficient C but not on the exponent m.

With the development of network technology, the application of integration systems are becoming more and more widely, as the data of integration system come from various data sources, which delay the user's response time. To address the issues of the performance in such systems, we introduce semantic caching mechanism in this paper. In addition, the key technology of semantic cache is discussed in details.

In this paper, we studied some new technologies and solutions for remote digital home control system. Although many solutions for remote digital home control system are being developed, few can be applied to real life because of different standard protocol. Each organization emphasizes on different area. Thus, we present a web server based remote control system to connect internet and isolated intelligent home control system, which can be widely used by common families. The web server is more flexible, reliable, and easy maintenance. Field Programming Gate Array (FPGA) is applied in our system as the core controller. This makes the system more efficiency and faster to achieve real-time control. Detailed implementation for client, web server and hardware design is presented in this paper. The experimental result shows users can not only control home appliances such as air conditioner, video camera and lighting ect., but also check their status in real-time from anywhere through our system.

Short Message Service (SMS) has become a widely used communication way for mobile phone users where Global System for Mobile communications (GSM) covered. Although the GSM and SMS technology are successful and mature, there is a lot of limitations existed such as GSM module can not be operated by multi-thread program. In this paper, an optimal SMS is proposed and used in remote controlling and monitoring system on Google Earth (GE). Using optimal SMS and COM API provided by GE, users can control GE to fly to anywhere and the state of the D-Link camera by short messages. Besides that, a voice guiding system(VGS) based on Microsoft speech SDK 5.1 is added to make voice introduction for the place.

Virtual community performs more and more important role for online users. Many tools for virtual community design, implementation and management have been developed, such as Virtual Reality (VR). On the other hand, few popular technologies have received frequent usage because of cost and time consuming. In this study, a platform for building virtual community more easily and quickly is proposed, which is called E-Life Platform (ELP) in our paper. ELP is based on Google Earth (GE) which provides high resolution global geographic information. The architecture of ELP system based on SketchUp is discussed in this paper. The detailed implementation of ELP is presented. Moreover, how to build a virtual community by using ELP is also described in this paper. Experimental results have shown the efficiency and low cost of ELP system.

A new system for constructing virtual community integrated GE and multi-applications is introduced in this paper. Although GE provides a good platform of 3D space for virtual community, only 3D scene is not enough. How to embed the interesting web-applications into GE to construct the large virtual community is studied. A system combines the e-commerce, 3D objects, entertainment and sight-seeing with GE is also implemented. The architecture of virtual community system and detailed design is illustrated. Both ecommerce and entertainment such as online game, blog, chatting and video on demand are implemented based on the COM API provided by GE. The experimental indicates have shown that the system is more flexible and easier to satisfy users' requirement compared with the most of virtual community.

A new PCR based method was developed to detect deleted mitochondrial DNA (mtDNA). Peripheral blood cell DNA was obtained from a victim who was accidently exposed to a 60Co radiation source in 1990. Using the DNA as template, first PCR was performed to generate multiple products including true deletions and artifacts. The full length product was recovered and used as template of secondary PCR. The suspicious deletion product of mtDNA could be confirmed only if it was yielded by first PCR. Using either original primers or their nested primers, the suspicious deletion product was amplified and authenticated as a true deletion product. The template was recovered and determined to be a deletion by sequencing directly. The results show that a new mtDNA deletion, which spans 889 bp from nt 11688 to nt 12576, was detected in the peripheral blood cells of the victim. It indicates that this new PCR-based method was more efficient at detecting small populations of mtDNA deletion than other routine methods. MtDNA deletion was found in the victim, suggesting the relationship between the deletion and phenotypes of the disease.

National Institutes of Health (U.S.) (EB-002804), National Institutes of Health (U.S.) (EB-002026)