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2 results on '"Newton-Bishop, J.A."'

1. The emergence of networks in human genome epidemiology - Challenges and opportunities

Author

Georgia Salanti, Patricia A. Buffler, Teri A. Manolio, André G. Uitterlinden, Molly S. Bray, Ross Duncan, Marta Gwinn, Nicholas J. Wareham, Mia Hashibe, Paolo Vineis, Marjo-Riitta Järvelin, Melissa L. Bondy, Muin J. Khoury, John P. A. Ioannidis, Julian Little, Daniela Seminara, David J. Hunter, Nelleke A. Gruis, Paul Brenchley, George Davey Smith, Elio Riboli, Thomas R. O'Brien, Paolo Boffetta, John Danesh, Julian P T Higgins, Deborah M. Winn, Emanuela Taioli, Nic Timpson, Beatrice Malmer, Siobhan M. Dolan, Anand P. Chokkalingam, Juan P. Casas, Jonine L. Bernstein, Julia Newton-Bishop, Ron Zimmern, Demetrius M. Maraganore, Internal Medicine, Seminara, D., Khoury, M.J., O'Brien, T.R., Manolio, T., Gwinn, M.L., Little, J., Higgins, J.P.T., Bernstein, J.L., Boffetta, P., Bondy, M., Bray, M.S., Brenchley, P.E., Buffler, P.A., Casas, J.P., Chokkalingam, A.P., Danesh, J., Smith, G.D., Dolan, S., Duncan, R., Gruis, N.A., Hashibe, M., Hunter, D., Jarvelin, M.-R., Malmer, B., Maraganore, D.M., Newton-Bishop, J.A., Riboli, E., Salanti, G., Taioli, E., Timpson, N., Uitterlinden, A.G., Vineis, P., Wareham, N., Winn, D.M., Zimmern, R., and Ioannidis, J.P.A.

Subjects
Information Services, Information Services/*organization & administration/standards/trends, Internet, medicine.medical_specialty, Hardware_MEMORYSTRUCTURES, Knowledge management, Human genome, Genome, Human, Epidemiology, business.industry, Public health, MEDLINE, Epidemiologic Methods, Resource (project management), Genetic epidemiology, Global network, Humans, Medicine, The Internet, business
Abstract

The Human Genome Epidemiology Network (HuGENet) recently launched a global network of consortia working on human genome epidemiology. This Network of Investigator Networks aims to create a resource to share information, offer methodologic support, generate inclusive overviews of studies conducted in specific fields, and to facilitate rapid confirmation of findings. In October 2005, HuGENet brought together representatives from established and emerging networks in order to share their experiences at a workshop in Cambridge, United Kingdom. In advance of the meeting, a qualitative questionnaire was distributed to workshop participants. The questionnaire elicited information on experiences and practices in building and maintaining consortia. This chapter reports on the numerous challenges and their possible solutions as identified by the workshop participants, as well as new opportunities offered by the network approach to genetic and genomic epidemiology.

Published
2007

2. A network of investigator networks in human genome epidemiology

Author

Thomas R. O'Brien, Paolo Boffetta, Georgia Salanti, Elio Riboli, Paolo Vineis, Julian Little, Emanuela Taioli, John Danesh, Julian P T Higgins, Muin J. Khoury, Deborah M. Winn, Daniela Seminara, Julia A. Newton Bishop, Demetrius M. Maraganore, Siobhan M. Dolan, John P. A. Ioannidis, Peter D. Inskip, André G. Uitterlinden, Marjo-Riitta Järvelin, Gloria M. Petersen, David J. Hunter, Jonine L. Bernstein, Patricia Hartge, Ioannidis, J.P.A., Bernstein, J., Boffetta, P., Danesh, J., Dolan, S., Hartge, P., Hunter, D., Inskip, P., Jarvelin, M.-R., Little, J., Maraganore, D.M., Newton Bishop, J.A., O'Brien, T.R., Petersen, G., Riboli, E., Seminara, D., Taioli, E., Uitterlinden, A.G., Vineis, P., Winn, D.M., Salanti, G., Higgins, J.P.T., Khoury, M.J., and Internal Medicine

Subjects
Standardization, Epidemiology, business.industry, Sound design, Genetic Diseases, Inborn, Data science, Field (computer science), Task (project management), Resource (project management), Investigator networks in human genome epidemiology, Meta-Analysis as Topic, Human Genome Project, Databases, Genetic, Medicine, Genetic Diseases, Inborn/*genetics, Humans, Multicenter Studies as Topic, Registries, business, Epidemiologic Methods
Abstract

The task of identifying genetic determinants for complex, multigenetic diseases is hampered by small studies, publication and reporting biases, and lack of common standards worldwide. The authors propose the creation of a network of networks that include groups of investigators collecting data for human genome epidemiology research. Twenty-three networks of investigators addressing specific diseases or research topics and representing several hundreds of teams have already joined this initiative. For each field, the authors are currently creating a core registry of teams already participating in the respective network. A wider international registry will include all other teams also working in the same field. Independent investigators are invited to join the registries and existing networks and to join forces in creating additional ones as needed. The network of networks aims to register these networks, teams, and investigators; be a resource for information about or connections to the many networks; offer methodological support; promote sound design and standardization of analytical practices; generate inclusive overviews of fields at large; facilitate rapid confirmation of findings; and avoid duplication of effort. Copyright © 2005 by the Johns Hopkins Bloomberg School of Public Health All rights reserved.

Published
2005
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