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1. Manoela N. Morais 1. is a graduate student in the department of finance at Pace University in New York. (mm78341n{at}pace.edu) 2. Matthew R. Morey 1. is professor in the department of finance at Pace University in New York. (mmorey{at}pace.edu) 1. To order reprints of this article, please contact David Rowe at d.rowe{at}pageantmedia.com or 646-891-2157. The file drawer problem is a publication bias where journal editors are much more likely to accept empirical papers with statistically significant results than those with statistically nonsignificant results. As a result, papers that have nonsignificant results are not published and relegated to the file drawer, never to be seen by others. In a previous paper, Morey and Yadav (2018), examined the file drawer problem in finance journals and found evidence that strongly suggests that such a publication bias exists in finance journals. In this follow-up study, we examine the prevalence of the file drawer problem at finance conferences. As such we are the first article in finance that we know of to attempt such an analysis. To do this, we examine every single empirical paper presented at the annual Financial Management Association (FMA) conference from 2014–2018. In an examination of 3,425 empirical papers, we found less than one-half of one percent of these papers had statistically nonsignificant results. These results suggest that there is also a significant file drawer problem at finance conferences. TOPIC: [Statistical methods][1] Key Findings [1]: https://www.iijournals.com/topic/statistical-methods

This paper describes a real case study combining two different approaches to optimize the logistics performance in a rent-a-car company, leading to the improvement of the vehicle delivery process, reducing the transport costs, and subsequently increasing the customer's satisfaction. The first approach involves the shortest path determination, using the Dijkstra algorithm applied to a parking lot layout using two scenarios named general and specific approaches, whose result was compared to the solution obtained by the application of the Floyd-Warshall algorithm. The second is related to the maximum flow determination by applying and comparing the Ford-Fulkerson and the Goldberg algorithms considering an operational bottleneck due to the seasonality and oscillatory nature of demands. Both approaches were simulated in MATLAB and analysed as a global decision support model.

Poster presentation at the V International Conference on Analytical Proteomics (ICAP 2017).

Manage the company process faster as possible and in the automated way has been one of the biggest challenges of the 21st century. Companies are constantly looking for the improvement of its processes in order to achieve a competitive advantage in the market and the reduction of internal costs. This challenge is particularly strong in government companies providing utility services to the population. The company Cagece (one basic sanitation company of the Brazilian government) know this problem and the difficulties it generated. In this paper, we present in a systematic way, a little about the problem, the suggested solution, and the results collected through the relationship disciplines of Software Engineering and BPM in order to show the innovation applied and to guide companies that search improvements in their processes.

As abóboras (Cucurbita spp, Cucurbitaceae) são muito utilizadas na alimentação humana devido seu elevado valor nutricional, porém nem todas as suas partes são aproveitadas, como as sementes. São utilizadas há muito tempo na medicina popular como vermífugo. Fatores como propriedades nutricionais, sabor agradável ao paladar, fácil acesso e baixo custo são alguns fatores que contribuem para que sementes de abóbora façam parte da alimentação diária da população seja ela na forma de complemento ou como snacks. Pensando nisso verificou-se a composição química e nutricional da semente de abóbora (Cucurbita spp) comercializadas salgadas, para comprovar dados da literatura em relação aos seus efeitos, e a quantidade de sódio presente. O elevado teor de fibras encontrado (29,01g±0,28) sugere a eficácia das sementes de abóbora na ação hipoglicemiante e laxativa e o baixo teor de carboidratos (5,36g) sugere seu consumo como benéfico para diabéticos, visto que necessitam de dietas com baixos teores de carboidratos. No entanto, por serem estas comercializadas salgadas, seu consumo deve ser de forma moderada uma vez que uma porção perfaza 23% do valor diário permitido de sódio.

The Solid Waste National Policy (SWNP) established by Law No. 12.305/2010 and regulated by Federal Decree No. 7404/2010 indicates advances in solid waste management in Brazil. The main one is the implementation of shared responsibility for the life cycle of products, operationalized through the Reverse Logistics system. This system seeks the restitution of solid waste to the business sector for reusing in the production chain or for environmentally appropriate disposal. The challenge and successful implementation of the SWNP requires the government’s strategic vision and a change in the behaviour of the Brazilian population. This process needs to be built through social debate and engagement of all stakeholders, from the social and economic inclusion of waste pickers in the recycling chain to the real commitment of entrepreneurs, transforming degrading jobs in entrepreneurship, combined with innovation. Despite the fact that the SWNP and other regulatory instruments generically indicate a stimulus to the incorporation of non-virgin raw materials in the production process of Electrical and Electronic Equipment (EEE), no concrete step in this direction has been found yet. The complex nature of the productive chain of electrical and electronic products gives an indication of the interlinked network of inter-relationships of the industrial system involved in it, once it depends on the integration of several industries. In this context, it is important to structure a management model for the reuse of industrial waste, based on the creation of a network – 5Rs Network – that allows to Reduce, Redesign, Recycle, Reuse and Repurpose the waste generated throughout the production cycle of the EEE in the country. This paper reveals which industrial sectors are related to the EEE

Primary spinal glioblastoma (GBM) is a rare disease, with an aggressive course and a poor prognosis. We report a case of a 19-year-old male with a 4-week history of progressive weakness in both lower limbs, which progressed to paraparesis with a left predominance and difficulty in initiating urination over a week. Spine magnetic resonance imaging (MRI) showed an intramedullary expansile mass localised between T6 and T11. We performed a laminotomy and laminoplasty between T6 and T11 and the tumour was partially removed. Histopathological study was compatible with GBM. The patient was administered focal spine radiotherapy with chemotherapy with temozolamide. Serial MRI performed after the initial surgery demonstrated enlargement of the enhancing mass from T3 to T12 and subarachnoid metastatic deposits in C2 and C4, the pituitary stalk, inter-peduncular cistern, left superior cerebellar peduncle and hydrocephalus. We review the literature with regard to the disease and treatment options, and report the unique features of this case. Primary spinal GBM is an extremely rare entity with a poor prognosis and a short survival time. An aggressive management of the different complications as they arise and improvement of current modes of treatment and new treatment options are required to improve survival and ensure better quality of life.

The reproductive effects of the coadministration of di-2-(ethylhexyl) phthalate (DEHP) and di-butyl phthalate (DBP) were studied in both foetal and adult male rat offspring exposed in utero. Pregnant Wistar rats were treated by oral gavage from gestation day 13 to 21 with vehicle control, 150 mg DEHP/kg body weight (bw)/day, 100 mg DBP/kg bw/ or a combination of the two compounds (DEHP 150 + DBP 100 mg/kg bw/day). An additional group of dams received 500 mg DBP/kg bw/day. A significant decrease in foetal testicular testosterone levels was observed in animals exposed to 500 mg DBP/kg/day or the phthalate mixture. Similarly, histological analysis of the foetal testis revealed that the coadministration of DEHP and DBP was able to increase the diameter of seminiferous cords and induce gonocyte multinucleation at doses that individually had no significant effects on these variables. However, in the phthalate mixture group, no significant changes were observed in anogenital distance and nipple retention, variables that are used to indicate possible anti-androgenic effects. Also, the adult endpoints investigated, that included reproductive organ weights and the number of spermatids per testis, were unaffected by any treatment regimen. Overall, coadministration of DEHP and DBP in utero significantly reduced testicular testosterone levels and resulted in misshapen seminiferous cords and gonocyte multinucleation in rat foetal testis. Our results also confirm that these foetal endpoints seem to be the most sensitive markers of prenatal phthalate exposure.

Gliosarcomas are rare tumours of the central nervous system, with a well-known capacity for metastasis. When they metastasise, the dissemination occurs more frequently via the haematogenous route to extraneural sites. Metastasis-spread through the cerebrospinal fluid is extremely rare. We present the case of a 58-year-old man who underwent a gross total resection of a lesion in the left temporal lobe. The histological findings revealed a gliosarcoma and the patient received radiotherapy followed by chemotherapy. Seven months after surgery, while the patient remained neurologically intact, brain and spinal cord MRI revealed tumour recurrence and neuroaxis metastases through the traffic routes of the cerebrospinal fluid. The patient died 8 months after the diagnosis. A PubMed search regarding metastatic gliosarcoma up to June 2015 was also carried out. To the best of our knowledge, this is the first case report of gliosarcoma metastases to the brain and spinal cord leptomeninges.

Background: Cavernous malformations (CMs) confined to the cranial nerves (CN) are extremely rare lesions. Case Description: The authors report 2 cases of CMs, one involving the trigeminal nerve presenting with a 3 years history of a refractory right trigeminal neuralgia that was microsurgically resected by a retromastoid approach with resolution of the neuralgia; and another CM involving the chiasma with an abrupt onset of vision loss with acute intralesional bleeding that was removed through a right pterional approach with vision improvement. Conclusion: Surgical resection is recommended in the context of progressive significant neurological deficit, emergency decompression as a result of recent hemorrhage for symptomatic relief or increase in size on serial magnetic resonance imaging (MRI).

Alkaline reflux gastritis is a clinical syndrome that results from a mucosal injury by duodenal contents. In this study, the amount of duodenogastric reflux was assessed in patients who previously underwent proximal gastric vagotomy (PGV group; n = 11) and PGV plus duodenoplasty (PGV+D group; n = 10) as a treatment for duodenal ulcer. The control group (A) consisted of 11 healthy volunteers without endoscopic abnormalities. A quantitative index of duodenogastric reflux was obtained in each case by determining the percentage of the injected dose of 99mTechnetium-DISIDA that was recovered by continuous aspiration of gastric juice in fasting subjects. In the PGV group, the percentage of administered 99mTechnetium-DISIDA recovered from the stomach (median: 0.69%; range: 0.09%-3.61%) did not differ significantly (P0.05) from that of the PGV+D group (median: 0.49%; range: 0.09%-3.91%) and from that of the A group (median: 1.47%; range: 0.22%-3.01%). The results show that proximal gastric vagotomy plus duodenoplasty did not increase duodenogastric reflux.

A comparative study on the gestational, neonatal, and perinatal death rates between September 1979-August 1980 and September 1980-August 1981 at the University Hospital, Federal University of Santa Maria was conducted. A significant difference was found between these 2 periods with regard to gestational and perinatal death rates. There were more deaths, gestational and neonatal, in fetuses less thann 38 weeks gestation. The majority of neonatal deaths occurred within 72 hours after birth (75.0%). Apgar scores of 7 at the 1st and 5th minutes were registered for 70.3 and 59.5% of the infants, respectively. Autopsy was not performed in the 1st study period while 70.0% of the cases in the 2nd period were examined postmortem. The number of perinatal deaths from those among the previous controls was significantly lower than from those patients otherwise treated. The increase in the number of outpatient cases, the adoption of new routines, as well as the reformulation of existing ones, the purchase of equipment to better evaluate fetal well-being, as well as other changes during the 2nd phase, are responsible for the lowering of perinatal mortality. (author's modified)