1. Helicobacter pylori infection does not protect against eosinophilic esophagitis: results from a large multicenter case-control study
- Author
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Molina-Infante, Javier, Gutierrez-Junquera, Carolina, Savarino, Edoardo, Penagini, Roberto, Modolell, Ines, Bartolo, Ottavia, Prieto-García, Alicia, Mauro, Aurelio, Alcedo, Javier, Perelló, Antonia, Guarner-Argente, Carlos, Alcaide, Noelia, Vegas, Ana M., Barros-García, Patricia, Murzi-Pulgar, Marianette, Perona, Monica, Gisbert, Javier P., Lucendo, Alfredo J., de Bortoli, Nicola, Costa, Valeria A., Dominguez-Jimenez, Jose Luis, Garcia-Romero, Ruth, Jimeno, Cristina, Marabotto, Elisa, Pajares-Diaz, Jose Antonio, Perez-Aisa, Angeles, Tolone, Salvatore, Ortiz, Vicente, Zerbib, Frank, Galera, Ana Pilar, Molina-Infante, Javier, Gutierrez-Junquera, Carolina, Savarino, Edoardo, Penagini, Roberto, Modolell, Ine, Bartolo, Ottavia, Prieto-García, Alicia, Mauro, Aurelio, Alcedo, Javier, Perelló, Antonia, Guarner-Argente, Carlo, Alcaide, Noelia, Vegas, Ana M., Barros-García, Patricia, Murzi-Pulgar, Marianette, Perona, Monica, Gisbert, Javier P., Lucendo, Alfredo J., de Bortoli, Nicola, Costa, Valeria A., Dominguez-Jimenez, Jose Lui, Garcia-Romero, Ruth, Jimeno, Cristina, Marabotto, Elisa, Pajares-Diaz, Jose Antonio, Perez-Aisa, Angele, Tolone, Salvatore, Ortiz, Vicente, Zerbib, Frank, and Galera, Ana Pilar
- Subjects
Adult ,Male ,medicine.medical_specialty ,Adolescent ,Colombia ,Gastroenterology ,Hepatology ,Serology ,Helicobacter Infections ,Atopy ,03 medical and health sciences ,Young Adult ,0302 clinical medicine ,Internal medicine ,Prevalence ,Medicine ,Humans ,Prospective Studies ,Prospective cohort study ,Eosinophilic esophagitis ,Child ,Asthma ,Aged ,biology ,Helicobacter pylori ,business.industry ,Case-control study ,Age Factors ,Odds ratio ,Eosinophilic Esophagitis ,Middle Aged ,medicine.disease ,biology.organism_classification ,Italy ,Spain ,030220 oncology & carcinogenesis ,Case-Control Studies ,030211 gastroenterology & hepatology ,Female ,France ,business - Abstract
Objectives: Rising trends in eosinophilic esophagitis (EoE) have been repeatedly linked to declining Helicobacter pylori (H. pylori) infection, mostly in retrospective studies. We aimed to prospectively evaluate this inverse association. Methods: Prospective case-control study conducted in 23 centers. Children and adults naïve to eradication therapy for H. pylori were included. Cases were EoE patients, whereas controls were defined by esophageal symptoms and
- Published
- 2017