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1. Redo isolated tricuspid valve surgery: prediction of in-hospital mortality using the TRI-SCORE

Author

Dreyfus, J, Bohbot, Y., Coisne, A, Lavie-Badie, Y, Riant, E, Modine, T, Le Tourneau, T, Tribouilloy, Christophe, Donal, E, Habib, G, Selton-Suty, C, Iung, B, Obadia, J, Audureau, E, Messika-Zeitoun, D, Centre cardiologique du Nord (CCN), CHU Amiens-Picardie, Mécanismes physiopathologiques et conséquences des calcifications vasculaires - UR UPJV 7517 (MP3CV), Université de Picardie Jules Verne (UPJV)-CHU Amiens-Picardie, CHU Lille, CHU Bordeaux [Bordeaux], European Infective Endocarditis Registry (Euro-Endo), Microbes évolution phylogénie et infections (MEPHI), Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS), Département de Cardiologie [Hôpital de la Timone - APHM], Assistance Publique - Hôpitaux de Marseille (APHM)- Hôpital de la Timone [CHU - APHM] (TIMONE), Service de Cardiologie [CHRU Nancy], Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy), Service de cardiologie [CHU Bichat], AP-HP - Hôpital Bichat - Claude Bernard [Paris], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Université Paris Diderot, Sorbonne Paris Cité, Hôpital Henri Mondor, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Henri Mondor-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12), Laboratoire d'Investigation Clinique (LIC), Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12), and University of Ottawa [Ottawa]

Subjects
Cardiology and Cardiovascular Medicine, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
Abstract

Background Redo isolated tricuspid valve surgery (ITVS) is rarely performed. The TRI-SCORE reliably predicts in-hospital mortality after ITVS on native valve but has not been tested in the setting of redo interventions. Purpose We aimed to compare the predictive value of the TRI-SCORE to other surgical risk scores for redo ITVS. Methods Using a mandatory administrative database, we identified all consecutive adult patients who underwent a redo ITVS at 12 French tertiary centers between 2007 and 2017. Baseline characteristics and outcomes were collected from chart review and the TRI-SCORE, Logistic EuroSCORE, EuroSCORE II and STS were calculated. Results We identified 70 patients who underwent a redo ITVS (mean age 54±15 years, 63% female). Prior intervention was a repair in 51% and a replacement in 49%. A tricuspid valve replacement was performed in all patients. In-hospital mortality was 10%. The TRI-SCORE was the only risk score associated with in-hospital mortality (p=0.01). Area under the receiver operating characteristic curve for the TRI-SCORE was 0.83, much higher than with logistic EuroSCORE (0.58), EuroSCORE II (0.61) or STS (0.59). The table presents the observed and predicted values of in-hospital mortality according to TRI-SCORE categories. Conclusion The TRI-SCORE accurately predicted in-hospital mortality after redo isolated tricuspid valve surgery and may guide the clinical decision-making process especially as transcatheter therapies are emerging. Funding Acknowledgement Type of funding sources: None.

Published
2022
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2. Predictors of Outcomes Following Transcatheter Edge-to-Edge Mitral Valve Repair

Author

Ben-Shoshan J, Overtchook P, Buithieu J, Mousavi N, Martucci G, Spaziano M, de Varennes B, Lachapelle K, Brophy J, Modine T, Baumbach A, Maisano F, Prendergast B, Tamburino C, Windecker S, Piazza N, Ben-Shoshan, J, Overtchook, P, Buithieu, J, Mousavi, N, Martucci, G, Spaziano, M, de Varennes, B, Lachapelle, K, Brophy, J, Modine, T, Baumbach, A, Maisano, F, Prendergast, B, Tamburino, C, Windecker, S, and Piazza, N

Published
2020

3. Predictors of Left Ventricular Outflow Tract Obstruction After Transcatheter Mitral Valve Replacement

Author

Yoon SH, Bleiziffer S, Latib A, Eschenbach L, Ancona M, Vincent F, Kim WK, Unbehaum A, Asami M, Dhoble A, Silaschi M, Frangieh AH, Veulemans V, Tang GHL, Kuwata S, Rampat R, Schmidt T, Patel AJ, Nicz PFG, Nombela-Franco L, Kini A, Kitamura M, Sharma R, Chakravarty T, Hildick-Smith D, Arnold M, de Brito FS, Jr., Jensen C, Jung C, Jilaihawi H, Smalling RW, Maisano F, Kasel AM, Treede H, Kempfert J, Pilgrim T, Kar S, Bapat V, Whisenant BK, Van Belle E, Delgado V, Modine T, Bax JJ, Makkar RR, Yoon, Sh, Bleiziffer, S, Latib, A, Eschenbach, L, Ancona, M, Vincent, F, Kim, Wk, Unbehaum, A, Asami, M, Dhoble, A, Silaschi, M, Frangieh, Ah, Veulemans, V, Tang, Ghl, Kuwata, S, Rampat, R, Schmidt, T, Patel, Aj, Nicz, Pfg, Nombela-Franco, L, Kini, A, Kitamura, M, Sharma, R, Chakravarty, T, Hildick-Smith, D, Arnold, M, de Brito, F, J, R., Jensen, C, Jung, C, Jilaihawi, H, Smalling, Rw, Maisano, F, Kasel, Am, Treede, H, Kempfert, J, Pilgrim, T, Kar, S, Bapat, V, Whisenant, Bk, Van Belle, E, Delgado, V, Modine, T, Bax, Jj, and Makkar, Rr

Published
2019

4. Outcomes of transcatheter mitral valve replacement for degenerated bioprostheses, failed annuloplasty rings, and mitral annular calcification

Author

Yoon SH, Whisenant BK, Bleiziffer S, Delgado V, Dhoble A, Schofer N, Eschenbach L, Bansal E, Murdoch DJ, Ancona M, Schmidt T, Yzeiraj E, Vincent F, Niikura H, Kim WK, Asami M, Unbehaun A, Hirji S, Fujita B, Silaschi M, Tang GHL, Kuwata S, Wong SC, Frangieh AH, Barker CM, Davies JE, Lauten A, Deuschl F, Nombela-Franco L, Rampat R, Nicz PFG, Masson JB, Wijeysundera HC, Sievert H, Blackman DJ, Gutierrez-Ibanes E, Sugiyama D, Chakravarty T, Hildick-Smith D, de Brito FS, Jr., Jensen C, Jung C, Smalling RW, Arnold M, Redwood S, Kasel AM, Maisano F, Treede H, Ensminger SM, Kar S, Kaneko T, Pilgrim T, Sorajja P, Van Belle E, Prendergast BD, Bapat V, Modine T, Schofer J, Frerker C, Kempfert J, Attizzani GF, Latib A, Schaefer U, Webb JG, Bax JJ, Makkar RR, Yoon, Sh, Whisenant, Bk, Bleiziffer, S, Delgado, V, Dhoble, A, Schofer, N, Eschenbach, L, Bansal, E, Murdoch, Dj, Ancona, M, Schmidt, T, Yzeiraj, E, Vincent, F, Niikura, H, Kim, Wk, Asami, M, Unbehaun, A, Hirji, S, Fujita, B, Silaschi, M, Tang, Ghl, Kuwata, S, Wong, Sc, Frangieh, Ah, Barker, Cm, Davies, Je, Lauten, A, Deuschl, F, Nombela-Franco, L, Rampat, R, Nicz, Pfg, Masson, Jb, Wijeysundera, Hc, Sievert, H, Blackman, Dj, Gutierrez-Ibanes, E, Sugiyama, D, Chakravarty, T, Hildick-Smith, D, de Brito, F, J, R., Jensen, C, Jung, C, Smalling, Rw, Arnold, M, Redwood, S, Kasel, Am, Maisano, F, Treede, H, Ensminger, Sm, Kar, S, Kaneko, T, Pilgrim, T, Sorajja, P, Van Belle, E, Prendergast, Bd, Bapat, V, Modine, T, Schofer, J, Frerker, C, Kempfert, J, Attizzani, Gf, Latib, A, Schaefer, U, Webb, Jg, Bax, Jj, and Makkar, Rr

Published
2019

7. Reply to the Editor

Author

Fayad, G., Modine, T., and Warembourg, H.

Subjects
Pulmonary and Respiratory Medicine, stomatognathic system, Surgery, Cardiology and Cardiovascular Medicine
Published
2005
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8. Transcatheter aortic valve replacement in obese patients: procedural vascular complications with the trans-femoral and trans-carotid access routes

Author

Alberto Alperi, Angela McInerney, Thomas Modine, Chekrallah Chamandi, Jose D Tafur-Soto, Marco Barbanti, Diego Lopez, Francisco Campelo-Parada, Asim N Cheema, Stefan Toggweiler, Francesco Saia, Ignacio Amat-Santos, Juan F Oteo, Viçent Serra, Maciej Dabrowski, Ramzi Abi-Akar, Natalia Giraldo Echavarria, Roberto Valvo, Javier Lopez-Pais, Anthony Matta, Mobeena Arif, Federico Moccetti, Miriam Compagnone, Siamak Mohammadi, Luis Nombela-Franco, Josep Rodés-Cabau, Institut Català de la Salut, [Alperi A] Quebec Heart & Lung Institute, Laval University, Quebec City, Canada. [McInerney A] Cardiovascular Institute, Hospital Clinico San Carlos, Madrid, Spain. [Modine T] Centre Hospitalier Universitaire de Lille, Lille, France. [Chamandi C] Hôpital européen Georges-Pompidou, Paris, France. [Tafur-Soto JD] The Ochsner Clinical School, Ochsner Medical Center, New Orleans, LA, USA. [Barbanti M] Ferrarotto Hospital, University of Catania, Catania, Italy. [Serra V] Vall d’Hebron Hospital Universitari, Barcelona, Spain, and Vall d'Hebron Barcelona Hospital Campus

Subjects
Pulmonary and Respiratory Medicine, Time Factors, intervenciones quirúrgicas::procedimientos quirúrgicos cardiovasculares::procedimientos quirúrgicos cardíacos::implantación de prótesis valvulares cardíacas::sustitución valvular aórtica con catéter [TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS], Pathological Conditions, Signs and Symptoms::Signs and Symptoms::Body Weight::Overweight::Obesity [DISEASES], Aortic Valve Stenosis, Otros calificadores::Otros calificadores::/efectos adversos [Otros calificadores], Persones obeses, Femoral Artery, Transcatheter Aortic Valve Replacement, enfermedades cardiovasculares::enfermedades cardíacas::enfermedades de las válvulas cardíacas::estenosis de la válvula aórtica [ENFERMEDADES], Treatment Outcome, Risk Factors, Aortic Valve, Vàlvula aòrtica - Estenosi - Cirurgia, Cateterisme cardíac - Complicacions, Other subheadings::Other subheadings::/adverse effects [Other subheadings], Surgical Procedures, Operative::Cardiovascular Surgical Procedures::Cardiac Surgical Procedures::Heart Valve Prosthesis Implantation::Transcatheter Aortic Valve Replacement [ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT], Humans, Surgery, afecciones patológicas, signos y síntomas::signos y síntomas::peso corporal::sobrepeso::obesidad [ENFERMEDADES], Obesity, Cardiovascular Diseases::Heart Diseases::Heart Valve Diseases::Aortic Valve Stenosis [DISEASES], Cardiology and Cardiovascular Medicine, Retrospective Studies
Abstract

OBJECTIVES Obesity may increase the risk of vascular complications in transfemoral (TF) transcatheter aortic valve replacement (TAVR) procedures. The transcarotid (TC) approach has recently emerged as an alternative access in TAVR. We sought to compare vascular complications and early clinical outcomes in obese patients undergoing TAVR either by TF or TC vascular access. METHODS Multicentre registry including obese patients undergoing TF- or TC-TAVR in 15 tertiary centres. All patients received newer-generation transcatheter heart valves. For patients exhibiting unfavourable ileo-femoral anatomic characteristics, the TC approach was favoured in 3 centres with experience with it. A propensity score analysis was performed for overcoming unbalanced baseline covariates. The primary end point was the occurrence of in-hospital vascular complications (Valve Academic Research Consortium-2 criteria). RESULTS A total of 539 patients were included, 454 (84.2%) and 85 (15.8%) had a TF and TC access, respectively. In the propensity-adjusted cohort (TF: 442 patients; TC: 85 patients), both baseline and procedural valve-related characteristics were well-balanced between groups. A significant decrease in vascular complications was observed in the TC group (3.5% vs 12% in the TF group, odds ratio: 0.26, 95% CI: 0.07–0.95, P = 0.037). There were no statistically significant differences between groups regarding in-hospital mortality (TC: 2.8%, TF: 1.5%), stroke (TC: 1.2%, TF: 0.4%) and life-threatening/major bleeding events (TC: 2.8%, TF: 3.8%). CONCLUSIONS In patients with obesity undergoing TAVR with newer-generation devices, the TC access was associated with a lower rate of vascular complications. Larger randomized studies are warranted to further assess the better approach for TAVR in obese patients.

Published
2021
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9. Transcatheter heart valve interventions: where are we? Where are we going?

Author

Cherif Sahyoun, Michael Haude, Helmut Baumgartner, Elena Andreassi Marinelli, Erika Saillant, Alec Vahanian, Martin Thoenes, Simon Redwood, Olaf Wendler, Jasmine Lennartz, Victoria Delgado, Marion Tschernich, Olivier Gerard, Evelyn Julia Zemke, Bernard Prendergast, Matthew Leafstedt, Karen Thomitzek, Markus Mueller, Bernard Iung, Lars Søndergaard, Thomas Modine, Jeroen J. Bax, Olaf Rörick, Francesco Maisano, Anders Himmelmann, Prendergast, Bd, Baumgartner, H, Delgado, V, Gerard, O, Haude, M, Himmelmann, A, Iung, B, Leafstedt, M, Lennartz, J, Maisano, F, Marinelli, Ea, Modine, T, Mueller, M, Redwood, Sr, Rorick, O, Sahyoun, C, Saillant, E, Sondergaard, L, Thoenes, M, Thomitzek, K, Tschernich, M, Vahanian, A, Wendler, O, Zemke, Ej, and Bax, Jj

Subjects
Aortic valve, medicine.medical_specialty, Psychological intervention, Heart Valve Diseases, Regurgitation (circulation), 030204 cardiovascular system & hematology, Prosthesis Design, Transcatheter Aortic Valve Replacement, 03 medical and health sciences, 0302 clinical medicine, Bicuspid aortic valve, Mitral valve, Tricuspid valve, medicine, Humans, Heart valve, Intensive care medicine, Heart Valve Prosthesis Implantation, business.industry, valvular heart disease, Heart valve disease, 030229 sport sciences, medicine.disease, Heart Valves, Progression-Free Survival, medicine.anatomical_structure, Heart Valve Prosthesis, cardiovascular system, Cardiology and Cardiovascular Medicine, business
Abstract

Transcatheter heart valve interventions have transformed the outcomes of patients with valvular heart disease (VHD) who are unfavourable candidates for surgery. Technological advances have allowed extension of these interventions to younger or lower risk patients and those with other forms of VHD and may in the future permit earlier treatment of VHD in less symptomatic patients or those with moderate disease. The balance of risks and benefits is likely to differ between lower and higher risk patients, and more evidence is needed to evaluate the net benefit of transcatheter technology in these groups. As academic researchers, clinicians, industry, and patient stakeholders collaborate to research these broader indications for transcatheter valve interventions, it is essential to address (i) device durability and deliverability, (ii) specific anatomical needs (e.g. bicuspid aortic valves, aortic regurgitation, mitral and tricuspid valve disease), (iii) operator training, and (iv) the reinforced importance of the multidisciplinary Heart Team.

Published
2018

10. Predictors of 1-Year Mortality After Transcatheter Aortic Valve Implantation in Patients With and Without Advanced Chronic Kidney Disease

Author

Yusuke Watanabe, Thierry Lefèvre, Nicolas Debry, Pablo Codner, Marco Barbanti, Kentaro Hayashida, Georg Nickenig, Fabien Praz, Israel M. Barbash, Johan Bosmans, Giuseppe Gargiulo, Alon Barsheshet, Amer Masalha, Jan Malte Sinning, Darren Mylotte, Ran Kornowski, Amos Levi, Thomas Modine, Stephan Windecker, Levi, A., Codner, P., Masalha, A., Gargiulo, G., Praz, F., Hayashida, K., Watanabe, Y., Mylotte, D., Debry, N., Barbanti, M., Lefevre, T., Modine, T., Bosmans, J., Windecker, S., Barbash, I., Sinning, J. -M., Nickenig, G., Barsheshet, A., and Kornowski, R.

Subjects
Male, Time Factors, medicine.medical_treatment, 030204 cardiovascular system & hematology, urologic and male genital diseases, Severity of Illness Index, Ventricular Dysfunction, Left, 0302 clinical medicine, Risk Factors, Cause of Death, 030212 general & internal medicine, 610 Medicine & health, Aged, 80 and over, Ejection fraction, Atrial fibrillation, Stroke volume, Prognosis, female genital diseases and pregnancy complications, Europe, Survival Rate, Cardiology, Female, Cardiology and Cardiovascular Medicine, Human, Glomerular Filtration Rate, medicine.medical_specialty, Time Factor, Prognosi, Renal function, Follow-Up Studie, Transcatheter Aortic Valve Replacement, 03 medical and health sciences, Internal medicine, Severity of illness, medicine, Animals, Humans, Renal replacement therapy, Renal Insufficiency, Chronic, business.industry, Animal, Risk Factor, Stroke Volume, Odds ratio, Aortic Valve Stenosis, medicine.disease, Aortic Valve Stenosi, Human medicine, business, Kidney disease, Follow-Up Studies
Abstract

Advanced chronic kidney disease (CKD) is an independent predictor of mortality in patients undergoing transcatheter aortic valve implantation (TAVI). We aimed to identify predictors of 1-year mortality in patients after TAVI stratified by the presence or absence of advanced CKD (defined as estimated glomerular filtration rate

Published
2017

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